condition found tbRes List
Aβ, Aβ aggregation: Click to Expand ⟱
Source:
Type:
Beta-Amyloid (Aβ): In Alzheimer’s disease, Aβ peptides tend to misfold and aggregate into oligomers and fibrils.
Scientific Papers found: Click to Expand⟱
3440- ALA,    Protective effects of alpha lipoic acid (ALA) are mediated by hormetic mechanisms
- Review, AD, NA
*ROS↓, *neuroP↑, *Aβ↓, *cardioP?,
3447- ALA,    Redox Active α-Lipoic Acid Differentially Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer and Its Control Cells
- in-vitro, AD, SH-SY5Y
*ATP↑, *MMP↑, *ROS↓, *GlucoseCon↑, *GSH↑, *neuroP↑, *cognitive↑, *Ach↑, *Inflam↓, *Aβ↓, OXPHOS↓,
3545- ALA,    Potential therapeutic effects of alpha lipoic acid in memory disorders
- Review, AD, NA
*neuroP↑, *Inflam↓, *VCAM-1↓, *5HT↑, *memory↑, *BioAv↝, *Half-Life↓, *NF-kB↓, *antiOx↑, *IronCh↑, *ROS↓, *ATP↑, *ChAT↑, *Ach↑, *cognitive↑, *lipid-P↓, *VitC↑, *VitE↑, *GSH↑, *SOD↑, *Catalase↑, *GPx↑, *Aβ↓,
3271- ALA,    Decrypting the potential role of α-lipoic acid in Alzheimer's disease
- Review, AD, NA
*antiOx↑, *memory↑, *neuroP↑, *Inflam↓, *IronCh↑, *NRF2↑, *BBB↑, *GlucoseCon↑, *Ach↑, *ROS↓, *p‑tau↓, *Aβ↓, *cognitive↑, *Hif1a↑, *Ca+2↓, *GLUT3↑, *GLUT4↑, *HO-1↑, *VEGF↑, *PDKs↓, *PDH↑, *VCAM-1↓, *GSH↑, *NRF2↑, *hepatoP↑, *ChAT↑,
3269- ALA,    Sulfur-containing therapeutics in the treatment of Alzheimer’s disease
- NA, AD, NA
*AChE↓, *GlucoseCon↑, *ACC↑, *GSH↑, *Aβ↓, *Catalase↑, *GSR↑, *GSTs↑, *NADPH↑, *NQO1↑, *iNOS↓, *NF-kB↓, *lipid-P↓, *BBB↑, *memory↑, *cognitive↑, *antiOx↑, *Inflam↓,
3549- ALA,    Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia
- Review, AD, NA
*Inflam↓, *other↝, *other↝, *neuroP↑, *BioAv↝, *adiP↑, *BBB↑, *Casp6↓, *Casp9↓, *TNF-α↓, *IL6↓, *IL1β↓, *ROS↓, *NO↓, *iNOS↓, *COX2↓, *JNK↓, *p‑NF-kB↓, *Aβ↓, *BP↓, *memory↑, *cAMP↑, *ERK↑, *Akt↑, cognitive?,
3546- ALA,    Cognitive and Mood Effect of Alpha-Lipoic Acid Supplementation in a Nonclinical Elder Sample: An Open-Label Pilot Study
- Study, AD, NA
*antiOx↑, *ROS↓, *cognitive∅, *lipid-P↓, *memory↑, *ChAT↑, *Acetyl-CoA↑, *Aβ↓, *BioAv↑, *BBB↑, *toxicity∅,
760- Bor,    Therapeutic Efficacy of Boric Acid Treatment on Brain Tissue and Cognitive Functions in Rats with Experimental Alzheimer’s Disease
- in-vivo, AD, NA
*memory↑, *ROS↓, *GSH↑, *Aβ↓, *Inflam↓, *MMP↑, *lipid-P↓, *Ca+2↓, *cognitive↑, *TOS↓,
2816- CUR,    NEUROPROTECTIVE EFFECTS OF CURCUMIN
- Review, AD, NA - Review, Park, NA
*neuroP↑, *Inflam↓, *antiOx↑, *BioAv↓, *AP-1↓, *NF-kB↓, *HATs↓, *HDAC↑, Dose↑, *ROS↓, *cognitive↑, *Aβ↓,
3576- CUR,    Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer's Disease
- Review, AD, NA
*Inflam↓, *antiOx↑, *memory↑, *Aβ↓, *BBB↑, *cognitive↑, *tau↓, *LDL↓, *AChE↓, *IL1β↓, *IronCh↑, *neuroP↑, *BioAv↝, *PI3K↑, *Akt↑, *NRF2↑, *HO-1↑, *Ferritin↑, *HO-2↓, *ROS↓, *Ach↑, *GSH↑, *Bcl-2↑, *ChAT↑,
3575- CUR,    The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
- in-vivo, AD, NA
*antiOx↓, *ROS↓, *IL1β↓, *Aβ↓, *Inflam↓, *toxicity↓,
3574- CUR,    The effect of curcumin (turmeric) on Alzheimer's disease: An overview
- Review, AD, NA
*antiOx↑, *Inflam↓, *lipid-P↓, *cognitive↑, *memory↑, *Aβ↓, *COX2↓, *ROS↓, *AP-1↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *SOD↑, *GSH↑, *HO-1↑, *IronCh↑, *BioAv↓, *Half-Life↝, *Dose↝, *BBB↑, *BioAv↑, *toxicity∅, *eff↑,
3232- EGCG,    (−)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer׳s disease model mice by upregulating neprilysin expression
- in-vivo, AD, NA
HDAC1↓, *HDAC1↓, *Aβ↓, *cognitive↑,
3237- EGCG,    (-)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer's disease model mice by upregulating neprilysin expression
- in-vivo, AD, NA
*HDAC↓, *Aβ↓, cognitive↑,
2861- FIS,    The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
- Review, Nor, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *ROS↓, *neuroP↑, *NO↑, BioAv↝, *BBB↑, *toxicity↑, *eff↑, *GSH↑, *SOD↑, *Aβ↓, *12LOX↓, *COX2↓, *Catalase↑, *Inflam↓, *TNF-α↓, *IL6↑, *lipid-P↓, NF-kB↓, IL1β↓, NRF2↑, HO-1↑, GSTs↑, cognitive↑,
2894- HNK,    Pharmacological features, health benefits and clinical implications of honokiol
- Review, Var, NA - Review, AD, NA
*BioAv↓, *neuroP↑, *BBB↑, *ROS↓, *Keap1↑, *NRF2↑, *Casp3↓, *SIRT3↑, *Rho↓, *ERK↓, *NF-kB↓, angioG↓, RAS↓, PI3K↓, Akt↓, mTOR↓, *memory↑, *Aβ↓, *PPARγ↑, *PGC-1α↑, NF-kB↓, Hif1a↓, VEGF↓, HO-1↓, Foxm1↓, p27↑, P21↑, CDK2↓, CDK4↓, CDK6↓, cycD1↓, Twist↓, MMP2↓, Rho↑, ROCK1↑, TumCMig↓, cFLIP↓, BMPs↑, OCR↑, ECAR↓, *AntiAg↑, *cardioP↑, *antiOx↑, *ROS↓, P-gp↓,
2869- HNK,    Nature's neuroprotector: Honokiol and its promise for Alzheimer's and Parkinson's
- Review, AD, NA - Review, Park, NA
*neuroP↑, *Inflam↓, *motorD↑, *Aβ↓, *p‑tau↓, *cognitive↑, *memory↑, *ERK↑, *p‑Akt↑, *PPARγ↑, *PGC-1α↑, *MMP↑, *mt-ROS↓, *SIRT3↑, *IL1β↓, *TNF-α↓, *GRP78/BiP↓, *CHOP↓, *NF-kB↓, *GSK‐3β↓, *β-catenin/ZEB1↑, *Ca+2↓, *AChE↓, *SOD↑, *Catalase↑, *GPx↑,
2916- LT,    Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies
- Review, Var, NA - Review, AD, NA - Review, Park, NA
proCasp9↓, CDC2↓, CycB↓, Casp9↑, Casp3↑, Cyt‑c↑, cycA1↑, CDK2↓, APAF1↑, TumCCA↑, P53↑, BAX↑, VEGF↓, Bcl-2↓, Apoptosis↑, p‑Akt↓, p‑EGFR↓, p‑ERK↓, p‑STAT3↓, cardioP↑, Catalase↓, SOD↓, *BioAv↓, *antiOx↓, *ROS↓, *NO↓, *GSTs↑, *GSR↑, *SOD↑, *Catalase↑, *lipid-P↓, PI3K↓, Akt↓, CDK2↓, BNIP3↑, hTERT↓, DR5↑, Beclin-1↑, TNF-α↓, NF-kB↓, IL1↓, IL6↓, EMT↓, FAK↓, E-cadherin↑, MDM2↓, NOTCH↓, MAPK↑, Vim↓, N-cadherin↓, Snail↓, MMP2↓, Twist↓, MMP9↓, ROS↑, MMP↓, *AChE↓, *MMP↑, *Aβ↓, *neuroP↑, Trx1↑, ROS↓, *NRF2↑, NRF2↓, *BBB↑, ChemoSen↑, GutMicro↑,
3532- Lyco,    Lycopene alleviates oxidative stress via the PI3K/Akt/Nrf2pathway in a cell model of Alzheimer’s disease
- in-vitro, AD, NA
*ROS↓, *PI3K↑, *Akt↑, *NRF2↑, *antiOx↑, *Aβ↓, *Apoptosis↓, *neuroP↑,
3489- MFrot,    Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer's disease mice.
- in-vivo, AD, NA
*Aβ↓, *motorD↑, *cognitive↑, *memory↑, *ROS↓,
3488- MFrot,    Rotating magnetic field improves cognitive and memory impairments in APP/PS1 mice by activating autophagy and inhibiting the PI3K/AKT/mTOR signaling pathway
- in-vivo, AD, NA
*cognitive↑, *memory↑, *neuroP↑, *Aβ↓, *PI3K↓, *Akt↓, *mTOR↓,
2963- PL,    Piperlongumine activates Sirtuin1 and improves cognitive function in a murine model of Alzheimer’s disease
- in-vitro, AD, HEK293
*SIRT1↑, *cognitive↑, *Aβ↓, *Inflam↓, *neuroP↑, memory↑, Dose↓, NAD↑,
3343- QC,    Quercetin, a Flavonoid with Great Pharmacological Capacity
- Review, Var, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *angioG↓, *Inflam↓, *BioAv↓, *Half-Life↑, *GSH↑, *SOD↑, *Catalase↑, *Nrf1↑, *BP↓, *cardioP↑, *IL10↓, *TNF-α↓, *Aβ↓, *GSK‐3β↓, *tau↓, *neuroP↑, *Pain↓, *COX2↓, *NRF2↑, *HO-1↑, *IL1β↓, *IL17↓, *MCP1↓, PKCδ↓, ERK↓, BAX↓, cMyc↓, KRAS↓, ROS↓, selectivity↑, tumCV↓, Apoptosis↑, TumCCA↑, eff↑, P-gp↓, eff↑, eff↑, eff↑, eff↑, CycB↓, CDK1↓, CDK4↓, CDK2↓, TOP2↓, Cyt‑c↑, cl‑PARP↑, MMP↓, HSP70/HSPA5↓, HSP90↓, MDM2↓, RAS↓, eff↑,
3380- QC,    Quercetin as a JAK–STAT inhibitor: a potential role in solid tumors and neurodegenerative diseases
- Review, Var, NA - Review, Park, NA - Review, AD, NA
JAK↓, STAT↓, Inflam↓, NO↓, COX2↓, CRP↓, selectivity↑, *neuroP↑, STAT3↓, cycD1↓, MMP2↓, STAT4↓, JAK2↓, TumCP↓, Diff↓, *eff↑, *IL6↓, *TNF-α↓, *IL1β↓, *Aβ↓,
3374- QC,    Therapeutic effects of quercetin in oral cancer therapy: a systematic review of preclinical evidence focused on oxidative damage, apoptosis and anti-metastasis
- Review, Oral, NA - Review, AD, NA
α-SMA↓, α-SMA↑, TumCP↓, tumCV↓, TumVol↓, TumCI↓, TumMeta↓, TumCMig↓, ROS↑, Apoptosis↑, BioAv↓, *neuroP↑, *antiOx↑, *Inflam↓, *Aβ↓, *cardioP↑, MMP↓, Cyt‑c↑, MMP2↓, MMP9↓, EMT↓, MMPs↓, Twist↓, Slug↓, Ca+2↑, AIF↑, Endon↑, P-gp↓, LDH↑, HK2↓, PKA↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, GRP78/BiP↑, Casp12↑, CHOP↑,
3336- QC,    Neuroprotective Effects of Quercetin in Alzheimer’s Disease
- Review, AD, NA
*neuroP↑, *lipid-P↓, *antiOx↑, *Aβ↓, *Inflam↓, *BBB↓, *NF-kB↓, *iNOS↓, *memory↑, *cognitive↑, *AChE↓, *MMP↑, *ROS↓, *ATP↑, *AMPK↑, *NADPH↓, *p‑tau↓,
3080- RES,    Resveratrol: A miraculous natural compound for diseases treatment
- Review, Var, NA
SIRT1↑, ROCK1↓, AMPK↑, *lipid-P↓, Aβ↓, COX2↓, angioG↓, Hif1a↓, VEGF↓,
3057- RES,    The therapeutic effect of resveratrol: Focusing on the Nrf2 signaling pathway
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*NRF2↑, *Keap1↓, *ROS↓, *Apoptosis↓, *Inflam↓, *antiOx↑, *hepatoP↑, *neuroP↑, *cardioP↑, *RenoP↑, *AntiCan↑, *memory↑, *SOD↑, *GPx↑, *Catalase↑, *MDA↓, *NRF2↑, *HO-1↑, *ROS↓, *Aβ↓, *iNOS↓, *COX2↓, *GSH↑, *HO-1⇅, *SIRT1↑,
3100- RES,    Neuroprotective effects of resveratrol in Alzheimer disease pathology
- Review, AD, NA
*neuroP↑, *BioAv↓, *Half-Life↓, *BioAv↑, *BBB↑, *NRF2↑, *BioAv↓, *BioAv↑, *SIRT1↑, *cognitive↑, *lipid-P↓, *HO-1↑, *SOD↑, *GSH↑, *GPx↑, *G6PD↑, *PPARγ↑, *AMPK↑, *Aβ↓,
3490- RF,    Multidimensional insights into the repeated electromagnetic field stimulation and biosystems interaction in aging and age-related diseases
- Review, AD, NA - Review, Park, NA
*OS↑, *memory↑, *cognitive↑, *memory↑, *Aβ↓, *eff↑, *HSF1↑, *HSP70/HSPA5↑,
3461- RF,    Electromagnetic Field Stimulation Therapy for Alzheimer’s Disease
- Review, AD, NA
*Aβ↓, *HSF1↑, *ROS↓, *Inflam↓, *cognitive↑, *memory↑, *eff↑,
3028- RosA,    Network pharmacology mechanism of Rosmarinus officinalis L.(Rosemary) to improve cell viability and reduces apoptosis in treating Alzheimer’s disease
- in-vitro, AD, HT22 - in-vivo, NA, NA
*Aβ↓, *Apoptosis↓, *antiOx↓, *neuroP↑, *eff↑, *IGF-1↑, *MMP9↑, *Src↓, *MAPK↓, *MMP↑,
3003- RosA,    Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
- Review, Var, NA - Review, AD, NA - Review, Park, NA
*Inflam↓, *antiOx↑, *neuroP↑, *IL6↓, *IL1β↓, *NF-kB↓, *PGE2↓, *COX2↓, *MMP↑, *memory↑, *ROS↓, *Aβ↓, *HMGB1↓, TumCG↓, MARK4↓, Zeb1↓, MDM2↓, BNIP3↑, ASC↑, NLRP3↓, PI3K↓, Akt↓, Casp1↓, E-cadherin↑, STAT3↓, TLR4↓, MMP↓, ICAM-1↓, AMPK↓, IL6↑, MMP2↓, Warburg↓, Bcl-xL↓, Bcl-2↓, TumCCA↑, EMT↓, TumMeta↓, mTOR↓, HSP27↓, Casp3↑, GlucoseCon↓, lactateProd↓, VEGF↓, p‑p65↓, GIT1↓, Foxm1↓, cycD1↓, CDK4↓, MMP9↓, HDAC2↓,
3321- SIL,    Silymarin (Milk thistle)
- Review, AD, NA
*neuroP↝, *Dose↝, *Half-Life?, *BioAv↝, *cognitive↑, *Aβ↓, *Inflam↓, *OS↑, *memory↑,
3320- SIL,    Neuroprotective Potential of Silymarin against CNS Disorders: Insight into the Pathways and Molecular Mechanisms of Action
- Review, AD, NA
*hepatoP↑, *neuroP↑, *ROS↓, *β-Amyloid↓, *Inflam↓, *Aβ↓, *NF-kB↓, *TNF-α↓, *TNF-β↓, *iNOS↓, *NO↓, *COX2↓,
3319- SIL,    Silymarin and neurodegenerative diseases: Therapeutic potential and basic molecular mechanisms
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *ROS↓, *Inflam↓, *Apoptosis↓, *BBB?, *tau↓, *NF-kB↓, *IL1β↓, *TNF-α↓, *IL4↓, *MAPK↓, *memory↑, *cognitive↑, *Aβ↓, *ROS↓, *lipid-P↓, *GSH↑, *MDA↓, *SOD↑, *Catalase↑, *AChE↓, *BChE↓, *p‑ERK↓, *p‑JNK↓, *p‑p38↓, *GutMicro↑, *COX2↓, *iNOS↓, *TLR4↓, *neuroP↑, *Strength↑, *AMPK↑, *MMP↑, *necrosis↓, *NRF2↑, *HO-1↑,
3555- TQ,    Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta1-42 infused rat model
- in-vivo, AD, NA
*memory↑, *BAX↓, *Aβ↓, *p‑tau↓, *AChE↓, *p‑Akt↓, *Ach↑, *Inflam↓,
3556- TQ,    Thymoquinone alleviates the experimentally induced Alzheimer’s disease inflammation by modulation of TLRs signaling
- in-vivo, AD, NA
*Inflam↓, *memory↑, *cognitive↑, *Aβ↑, *TNF-α↓, *IL1β↓, *TLR2↓, *NF-kB↓, *IRF3↓, TLR4↓, MyD88↓, TRIF↓,
3571- TQ,    The Role of Thymoquinone in Inflammatory Response in Chronic Diseases
- Review, Var, NA - Review, Stroke, NA
*BioAv↓, *BioAv↑, *Inflam↓, *antiOx↑, *ROS↓, *GSH↑, *GSTs↑, *MPO↓, *NF-kB↓, *COX2↓, *IL1β↓, *TNF-α↓, *IFN-γ↓, *IL6↓, *cardioP↑, *lipid-P↓, *TAC↑, *RenoP↑, Apoptosis↑, TumCCA↑, TumCP↓, TumCMig↓, angioG↓, TNF-α↓, NF-kB↓, ROS↑, EMT↓, *Aβ↓, *p‑tau↓, *BACE↓, *TLR2↓, *TLR4↓, *MyD88↓, *IRF3↓, *eff↑, eff↑, DNAdam↑, *iNOS↓,
3570- TQ,    Thymoquinone alleviates the experimentally induced Alzheimer's disease inflammation by modulation of TLRs signaling
- in-vivo, AD, NA
*Inflam↓, *Aβ↓, *TNF-α↓, *IL1β↓, *TLR2↓, *IRF3↓, *TLR4↓, *memory↑, *NF-kB↓, *MyD88↓, *TRIF↓, *BBB↑, *cognitive↑,
3565- TQ,    Thymoquinone as a potential therapeutic for Alzheimer’s disease in transgenic Drosophila melanogaster model
*cognitive↑, *ROS↓, *SOD↑, *AChE↝, *Aβ↓,
3564- TQ,    The Potential Neuroprotective Effect of Thymoquinone on Scopolamine-Induced In Vivo Alzheimer's Disease-like Condition: Mechanistic Insights
- in-vivo, AD, NA
*Inflam↓, *AntiCan↑, *antiOx↑, *neuroP↑, *cognitive↑, *Aβ↓, *PPARγ↑, *NF-kB↓, *p‑tau↓, *MMP↑, *memory↑, *NF-kB↓, *ROS↓,
3557- TQ,    Thymoquinone protects against lipopolysaccharides-induced neurodegeneration and Alzheimer-like model in mice.
- in-vivo, AD, NA
*Inflam↓, *antiOx↑, *cognitive↑, *TNF-α↓, *IL1β↓, *AChE↓, *IL10↑, *ChAT↑, *Aβ↓,
3559- TQ,    Molecular signaling pathway targeted therapeutic potential of thymoquinone in Alzheimer’s disease
- Review, AD, NA - Review, Var, NA
*antiOx↑, *Inflam↑, *AChE↓, AntiCan↑, *cardioP↑, *RenoP↑, *neuroP↑, *hepatoP↑, TumCG↓, Apoptosis↑, PI3K↓, Akt↑, TumCCA↑, angioG↓, *NF-kB↓, *TLR2↓, *TLR4↓, *MyD88↓, *TRIF↓, *IRF3↓, *IL1β↓, *IL6↓, *IL12↓, *NRF2↑, *COX2↓, *VEGF↓, *MMP9↓, *cMyc↓, *cycD1↓, *TumCP↓, *TumCI↓, *MDA↓, *TGF-β↓, *CRP↓, *Casp3↓, *GSH↑, *IL10↑, *iNOS↑, *lipid-P↓, *SOD↑, *H2O2↓, *ROS↓, *LDH↓, *Catalase↑, *GPx↑, *AChE↓, *cognitive↑, *MAPK↑, *JNK↑, *BAX↓, *memory↑, *Aβ↓, *MMP↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 44

Results for Effect on Cancer/Diseased Cells:
AIF↑,1,   Akt↓,3,   Akt↑,1,   p‑Akt↓,1,   AMPK↓,1,   AMPK↑,1,   angioG↓,4,   AntiCan↑,1,   APAF1↑,1,   Apoptosis↑,5,   ASC↑,1,   Aβ↓,1,   BAX↓,1,   BAX↑,1,   Bcl-2↓,2,   Bcl-xL↓,1,   Beclin-1↑,1,   BioAv↓,1,   BioAv↝,1,   BMPs↑,1,   BNIP3↑,2,   Ca+2↑,1,   cardioP↑,1,   Casp1↓,1,   Casp12↑,1,   Casp3↑,2,   Casp9↑,1,   proCasp9↓,1,   Catalase↓,1,   CDC2↓,1,   CDK1↓,1,   CDK2↓,4,   CDK4↓,3,   CDK6↓,1,   cFLIP↓,1,   ChemoSen↑,1,   CHOP↑,1,   cMyc↓,1,   cognitive?,1,   cognitive↑,2,   COX2↓,2,   CRP↓,1,   cycA1↑,1,   CycB↓,2,   cycD1↓,3,   Cyt‑c↑,3,   Diff↓,1,   DNAdam↑,1,   Dose↓,1,   Dose↑,1,   DR5↑,1,   E-cadherin↑,2,   ECAR↓,1,   eff↑,7,   p‑EGFR↓,1,   EMT↓,4,   Endon↑,1,   ERK↓,1,   p‑ERK↓,1,   FAK↓,1,   Foxm1↓,2,   GIT1↓,1,   GlucoseCon↓,2,   Glycolysis↓,1,   GRP78/BiP↑,1,   GSTs↑,1,   GutMicro↑,1,   HDAC1↓,1,   HDAC2↓,1,   Hif1a↓,2,   HK2↓,1,   HO-1↓,1,   HO-1↑,1,   HSP27↓,1,   HSP70/HSPA5↓,1,   HSP90↓,1,   hTERT↓,1,   ICAM-1↓,1,   IL1↓,1,   IL1β↓,1,   IL6↓,1,   IL6↑,1,   Inflam↓,1,   JAK↓,1,   JAK2↓,1,   KRAS↓,1,   lactateProd↓,2,   LDH↑,1,   MAPK↑,1,   MARK4↓,1,   MDM2↓,3,   memory↑,1,   MMP↓,4,   MMP2↓,5,   MMP9↓,3,   MMPs↓,1,   mTOR↓,2,   MyD88↓,1,   N-cadherin↓,1,   NAD↑,1,   NF-kB↓,4,   NLRP3↓,1,   NO↓,1,   NOTCH↓,1,   NRF2↓,1,   NRF2↑,1,   OCR↑,1,   OXPHOS↓,1,   P-gp↓,3,   P21↑,1,   p27↑,1,   P53↑,1,   p‑p65↓,1,   cl‑PARP↑,1,   PI3K↓,4,   PKA↓,1,   PKCδ↓,1,   RAS↓,2,   Rho↑,1,   ROCK1↓,1,   ROCK1↑,1,   ROS↓,2,   ROS↑,3,   selectivity↑,2,   SIRT1↑,1,   Slug↓,1,   Snail↓,1,   SOD↓,1,   STAT↓,1,   STAT3↓,2,   p‑STAT3↓,1,   STAT4↓,1,   TLR4↓,2,   TNF-α↓,2,   TOP2↓,1,   TRIF↓,1,   Trx1↑,1,   TumCCA↑,5,   TumCG↓,2,   TumCI↓,1,   TumCMig↓,3,   TumCP↓,3,   tumCV↓,2,   TumMeta↓,2,   TumVol↓,1,   Twist↓,3,   VEGF↓,4,   Vim↓,1,   Warburg↓,1,   Zeb1↓,1,   α-SMA↓,1,   α-SMA↑,1,  
Total Targets: 152

Results for Effect on Normal Cells:
12LOX↓,1,   5HT↑,1,   ACC↑,1,   Acetyl-CoA↑,1,   Ach↑,5,   AChE↓,10,   AChE↝,1,   adiP↑,1,   Akt↓,1,   Akt↑,3,   p‑Akt↓,1,   p‑Akt↑,1,   AMPK↑,3,   angioG↓,1,   AntiAg↑,1,   AntiCan↑,2,   antiOx↓,3,   antiOx↑,19,   AP-1↓,2,   Apoptosis↓,4,   ATP↑,3,   Aβ↓,42,   Aβ↑,1,   BACE↓,1,   BAX↓,2,   BBB?,1,   BBB↓,1,   BBB↑,11,   BChE↓,1,   Bcl-2↑,1,   BioAv↓,8,   BioAv↑,5,   BioAv↝,4,   BP↓,2,   Ca+2↓,3,   cAMP↑,1,   cardioP?,1,   cardioP↑,6,   Casp3↓,2,   Casp6↓,1,   Casp9↓,1,   Catalase↑,9,   ChAT↑,5,   CHOP↓,1,   cMyc↓,1,   cognitive↑,25,   cognitive∅,1,   COX2↓,10,   CRP↓,1,   cycD1↓,1,   Dose↝,2,   eff↑,7,   ERK↓,1,   ERK↑,2,   p‑ERK↓,1,   Ferritin↑,1,   G6PD↑,1,   GlucoseCon↑,3,   GLUT3↑,1,   GLUT4↑,1,   GPx↑,5,   GRP78/BiP↓,1,   GSH↑,14,   GSK‐3β↓,2,   GSR↑,2,   GSTs↑,3,   GutMicro↑,1,   H2O2↓,1,   Half-Life?,1,   Half-Life↓,2,   Half-Life↑,1,   Half-Life↝,1,   HATs↓,1,   HDAC↓,1,   HDAC↑,1,   HDAC1↓,1,   hepatoP↑,4,   Hif1a↑,1,   HMGB1↓,1,   HO-1↑,7,   HO-1⇅,1,   HO-2↓,1,   HSF1↑,2,   HSP70/HSPA5↑,1,   IFN-γ↓,1,   IGF-1↑,1,   IL10↓,1,   IL10↑,2,   IL12↓,1,   IL17↓,1,   IL1β↓,14,   IL4↓,1,   IL6↓,5,   IL6↑,1,   Inflam↓,28,   Inflam↑,1,   iNOS↓,7,   iNOS↑,1,   IRF3↓,4,   IronCh↑,4,   JNK↓,1,   JNK↑,1,   p‑JNK↓,1,   Keap1↓,1,   Keap1↑,1,   LDH↓,1,   LDL↓,1,   lipid-P↓,13,   MAPK↓,2,   MAPK↑,1,   MCP1↓,1,   MDA↓,3,   memory↑,25,   MMP↑,10,   MMP9↓,1,   MMP9↑,1,   motorD↑,2,   MPO↓,1,   mTOR↓,1,   MyD88↓,3,   NADPH↓,1,   NADPH↑,1,   necrosis↓,1,   neuroP↑,27,   neuroP↝,1,   NF-kB↓,16,   p‑NF-kB↓,1,   NO↓,3,   NO↑,1,   NQO1↑,1,   Nrf1↑,1,   NRF2↑,12,   OS↑,2,   other↝,2,   p‑p38↓,1,   Pain↓,1,   PDH↑,1,   PDKs↓,1,   PGC-1α↑,2,   PGE2↓,1,   PI3K↓,1,   PI3K↑,2,   PPARγ↑,4,   RenoP↑,3,   Rho↓,1,   ROS↓,30,   mt-ROS↓,1,   SIRT1↑,3,   SIRT3↑,2,   SOD↑,11,   Src↓,1,   Strength↑,1,   TAC↑,1,   tau↓,3,   p‑tau↓,6,   TGF-β↓,1,   TLR2↓,4,   TLR4↓,4,   TNF-α↓,12,   TNF-β↓,1,   TOS↓,1,   toxicity↓,1,   toxicity↑,1,   toxicity∅,2,   TRIF↓,2,   TumCI↓,1,   TumCP↓,1,   VCAM-1↓,2,   VEGF↓,1,   VEGF↑,1,   VitC↑,1,   VitE↑,1,   β-Amyloid↓,1,   β-catenin/ZEB1↑,1,  
Total Targets: 174

Scientific Paper Hit Count for: Aβ, Aβ aggregation
8 Thymoquinone
7 Alpha-Lipoic-Acid
4 Curcumin
4 Quercetin
3 Resveratrol
3 Silymarin (Milk Thistle) silibinin
2 EGCG (Epigallocatechin Gallate)
2 Honokiol
2 Magnetic Field Rotating
2 Radio Frequency
2 Rosmarinic acid
1 Boron
1 Fisetin
1 Luteolin
1 Lycopene
1 Piperlongumine
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1333  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page