Aβ Cancer Research Results

Aβ, Aβ aggregation: Click to Expand ⟱
Source:
Type:
Beta-Amyloid (Aβ): In Alzheimer’s disease, Aβ peptides tend to misfold and aggregate into oligomers and fibrils.
Scientific Papers found: Click to Expand⟱
6461- 1,8-Cin,    1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases
- Review, AD, NA - Review, Var, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *Half-Life↝, *toxicity↓, *PGE2↓, *TNF-α↓, *IL1β↓, *NO↓, *NF-kB↓, *PPARγ↓, COX2/PTGS2↓, *ROS↓, *SOD↑, *Catalase↑, *TAC↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *NADPH↑, *GPx↑, *AntiBio↑, *eff↑, *AntiFungal↑, *AntiViral↑, *TRPA1↑, eff↑, TumCCA↑, ROS↑, MAPK↝, mTOR↝, Apoptosis↑, survivin↓, Akt↓, p38↑, cl‑PARP↑, cl‑Casp3⇅, P53↑, BAX↑, Cyt‑c↑, Casp9↑, Dose↝, *Aβ↓, *tau↓, *GSK‐3β↓, *BACE/β-secretase↓, *cardioP↑, MFN2↑,
7842- AAL,  ISQ,  RT,    Annona atemoya leaf extract ameliorates cognitive impairment in amyloid-β injected Alzheimer's disease-like mouse model
- in-vivo, AD, HT22
*Aβ↓, *ROS↓, *Apoptosis↓, *memory↑, *BDNF↓, *Dose↝, *neuroP↑,
3864- ACNs,    Anthocyanins Potentially Contribute to Defense against Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *Aβ↓, *ROS↓, *cognitive↑, *APP↓, *BBB↑, *Ca+2↓, *ATP↑, *BACE/β-secretase↓, *p‑NF-kB↓, *TNF-α↓, *iNOS↓,
3269- ALA,    Sulfur-containing therapeutics in the treatment of Alzheimer’s disease
- NA, AD, NA
*AChE↓, *GlucoseCon↑, *ACC↑, *GSH↑, *Aβ↓, *Catalase↑, *GSR↑, *GSTs↑, *NADPH↑, *NQO1↑, *iNOS↓, *NF-kB↓, *lipid-P↓, *BBB↑, *memory↑, *cognitive↑, *antiOx↑, *Inflam↓,
3271- ALA,    Decrypting the potential role of α-lipoic acid in Alzheimer's disease
- Review, AD, NA
*antiOx↑, *memory↑, *neuroP↑, *Inflam↓, *IronCh↑, *NRF2↑, *BBB↑, *GlucoseCon↑, *Ach↑, *ROS↓, *p‑tau↓, *Aβ↓, *cognitive↑, *Hif1a↑, *Ca+2↓, *GLUT3↑, *GLUT4↑, *HO-1↑, *VEGF↑, *PDKs↓, *PDH↑, *VCAM-1↓, *GSH↑, *NRF2↑, *hepatoP↑, *ChAT↑,
3440- ALA,    Protective effects of alpha lipoic acid (ALA) are mediated by hormetic mechanisms
- Review, AD, NA
*ROS↓, *neuroP↑, *Aβ↓, *cardioP?,
3447- ALA,    Redox Active α-Lipoic Acid Differentially Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer and Its Control Cells
- in-vitro, AD, SH-SY5Y
*ATP↑, *MMP↑, *ROS↓, *GlucoseCon↑, *GSH↑, *neuroP↑, *cognitive↑, *Ach↑, *Inflam↓, *Aβ↓, OXPHOS↓,
3549- ALA,    Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia
- Review, AD, NA
*Inflam↓, *other↝, *other↝, *neuroP↑, *BioAv↝, *adiP↑, *BBB↑, *Casp6↓, *Casp9↓, *TNF-α↓, *IL6↓, *IL1β↓, *ROS↓, *NO↓, *iNOS↓, *COX2/PTGS2↓, *JNK↓, *p‑NF-kB↓, *Aβ↓, *BP↓, *memory↑, *cAMP↑, *ERK↑, *Akt↑, cognitive?,
3546- ALA,    Cognitive and Mood Effect of Alpha-Lipoic Acid Supplementation in a Nonclinical Elder Sample: An Open-Label Pilot Study
- Study, AD, NA
*antiOx↑, *ROS↓, *cognitive∅, *lipid-P↓, *memory↑, *ChAT↑, *Acetyl-CoA↑, *Aβ↓, *BioAv↑, *BBB↑, *toxicity∅,
3545- ALA,    Potential therapeutic effects of alpha lipoic acid in memory disorders
- Review, AD, NA
*neuroP↑, *Inflam↓, *VCAM-1↓, *5HT↑, *memory↑, *BioAv↝, *Half-Life↓, *NF-kB↓, *antiOx↑, *IronCh↑, *ROS↓, *ATP↑, *ChAT↑, *Ach↑, *cognitive↑, *lipid-P↓, *VitC↑, *VitE↑, *GSH↑, *SOD↑, *Catalase↑, *GPx↑, *Aβ↓,
7396- Amla,    Enhancing cognitive memory function using Phyllanthus emblica polysaccharides via modulating autophagy and reshaping the gut microbiota
- in-vivo, AD, NA
*Inflam↓, *antiOx↓, *GutMicro↑, *cognitive↑, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *IL4↑, *IL10↑, *TAC↑, *ATG5↑, *Beclin-1/ATG6↑, *LC3B↑, *LRP1↑, *BACE/β-secretase↓, *APP↓, *Aβ↓, *tau↓,
3887- Api,    The flavonoid apigenin protects brain neurovascular coupling against amyloid-β₂₅₋₃₅-induced toxicity in mice
- in-vivo, AD, NA
*Inflam↓, *ROS↓, *Aβ↓, *memory↑, *AChE↓, *Ach↑, *Dose↑, *BDNF↑, *TrkB↑, *p‑CREB↑, *BBB↑, *Ca+2?,
3884- Api,    Neuroprotective, Anti-Amyloidogenic and Neurotrophic Effects of Apigenin in an Alzheimer’s Disease Mouse Model
- in-vivo, AD, NA
*memory↑, *Aβ↓, *BACE/β-secretase↓, *antiOx↑, *BDNF↑, *p‑CREB↑, *p‑ERK↑, *ROS↓, *SOD↑, *GPx↑, *neuroP↑,
3882- Api,    Enhancing Amyloid-β Clearance May Improve Brain Function in Alzheimer Disease
- Review, AD, NA
*AQPs↑, *Aβ↓,
4280- Api,    Protective effects of apigenin in neurodegeneration: An update on the potential mechanisms
- Review, AD, NA - Review, Park, NA
*neuroP↑, *antiOx↑, *ROS↓, *Inflam↓, *TNF-α↓, *IL1β↓, *PI3K↑, *Akt↑, *BBB↑, *NRF2↑, *SOD↑, *GPx↑, *MAPK↓, *Catalase↑, *HO-1↑, *COX2/PTGS2↓, *PGE2↓, *PPARγ↑, *TLR4↓, *GSK‐3β↓, *Aβ↓, *NLRP3↓, *BDNF↑, *TrkB↑, *GABA↑, *AChE↓, *Ach↑, *5HT↑, *cognitive↑, *MAOA↓,
3819- Aroma,    Aromatherapy improves cognitive dysfunction in senescence-accelerated mouse prone 8 by reducing the level of amyloid beta and tau phosphorylation
- Human, AD, NA - in-vitro, AD, NA
*cognitive↑, *Dose↝, *Aβ↓, *tau↓, *BDNF↑, *motorD↑,
3675- Ash,    Ashwagandha (Withania somnifera) Reverses β-Amyloid1-42 Induced Toxicity in Human Neuronal Cells: Implications in HIV-Associated Neurocognitive Disorders (HAND)
*memory↑, *neuroP↑, *Aβ↓, *LDH↓, *PPARγ↑, *cognitive↑,
3668- Ash,    Withania somnifera reverses Alzheimer's disease pathology by enhancing low-density lipoprotein receptor-related protein in liver
- NA, AD, NA
*Aβ↓, *cognitive↑,
3687- Ash,    Role of Withaferin A and Its Derivatives in the Management of Alzheimer’s Disease: Recent Trends and Future Perspectives
- Review, AD, NA
*Aβ↓, *tau↓, *HSPs↝, *antiOx↑, *ROS↓, *Inflam↓, *neuroP↑, *cognitive↑, *NF-kB↓, *HO-1↑, *memory↑, *AChE↓, *BChE↓, *ChAT↑, *Ach↑,
3688- Ash,    Withaferin A Suppresses Beta Amyloid in APP Expressing Cells: Studies for Tat and Cocaine Associated Neurological Dysfunctions
- NA, AD, SH-SY5Y
*Aβ↓, *neuroP↑,
4303- Ash,    Ashwagandha (Withania somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review
- Review, AD, NA
*neuroP↑, *Sleep↑, *Inflam↓, *cardioP↑, *cognitive↑, *Aβ↓, *TNF-α↓, *IL1β↓, *IL6↓, *MCP1/CCL2↓, *lipid-P↓, *tau↓, *ROS↓, *BBB↑, *AChE↓, *GSH↑, *GSTs↑, *GSR↑, *GPx↑, *SOD↑, *Catalase↑, ChemoSen↑, *Strength↑,
5425- ASTX,    Multiple roles of fucoxanthin and astaxanthin against Alzheimer's disease: Their pharmacological potential and therapeutic insights
- in-vivo, AD, NA
*neuroP↑, *antiOx↑, *Inflam↑, *AChE↓, *BACE/β-secretase↓, *MAOA↓, *Aβ↓, *memory↑, *MDA↓, *SOD↑, *NRF2↑, *HO-1↑, *NF-kB↓, *GSK‐3β↓, *ChAT↑, *iNOS↓, *ROS↓, *BBB↑,
3833- BBR,    Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer’s Disease
- Review, AD, NA
*cardioP↑, *neuroP↑, *memory↑, *Aβ↓,
3754- BBR,  CUR,  EGCG,  Hup,    Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer’s disease: A review
*AChE↓, *Aβ↓, *LDL↓, *RenoP↑, *BChE↓, *eff↑, *BACE/β-secretase↓, *AChE↓, *eff↑,
3677- BBR,    Berberine: A Potential Multipotent Natural Product to Combat Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *AChE↓, *BChE↓, *MAOA↓, *Aβ↓, *LDL↓, *ROS↓, *RNS↓, *lipid-P↓, *Dose↝, *MAOB↓, *memory↑, *toxicity↓, *BBB↑,
3678- BBR,    Network pharmacology study on the mechanism of berberine in Alzheimer’s disease model
- Review, AD, NA
*APP↓, *PPARγ↑, *NF-kB↓, *Aβ↓, *cognitive↑, *antiOx↑, *Inflam↓, *Apoptosis↓, *BioAv↑, *BioAv↝, *BBB↑, *motorD↑, *NRF2↑, *HO-1↑, *ROS↓, *p‑Akt↑, *p‑ERK↑,
3679- BBR,    Berberine alleviates Alzheimer's disease by activating autophagy and inhibiting ferroptosis through the JNK-p38MAPK signaling pathway
- in-vivo, AD, NA
*Beclin-1/ATG6↑, *LC3B↑, *p62↓, *ROS↓, *lipid-P↓, *MDA↓, *Ferroptosis↓, *TfR1/CD71↓, *FTH1↑, *memory↑, *JNK↓, *p38↓, *Aβ↓, *Inflam↓,
3680- BBR,    Network pharmacology reveals that Berberine may function against Alzheimer’s disease via the AKT signaling pathway
- in-vivo, AD, NA
*Akt↑, *neuroP↑, *p‑ERK↑, *Aβ↓, *Inflam↓, *ROS↓, *BioAv↑, *BBB↑, *Half-Life↝, *memory↑, *cognitive↑, *HSP90↑, *APP↓, *mTOR↓, *P70S6K↓, *CD31/PECAM-1↑, *VEGF↑, *N-cadherin↑, *Apoptosis↓,
3682- BBR,    Berberine Improves Cognitive Impairment by Simultaneously Impacting Cerebral Blood Flow and β-Amyloid Accumulation in an APP/tau/PS1 Mouse Model of Alzheimer’s Disease
- in-vitro, AD, NA
*cognitive↑, *Aβ↓, *Apoptosis↓, *CD31/PECAM-1↑, *VEGF↑, *N-cadherin↑, *angioG↑, *neuroP↑, *p‑tau↓, *antiOx↑, *AChE↓, *MAOB↓, *lipid-P↓,
4300- BBR,    Effect of berberine on cognitive function and β-amyloid precursor protein in Alzheimer’s disease models: a systematic review and meta-analysis
- Review, AD, NA
*APP↓, *cognitive↑, *Aβ↓, *BACE/β-secretase↓, *tau?,
5565- betaCar,    β-Carotene, a Potent Amyloid Aggregation Inhibitor, Promotes Disordered Aβ Fibrillar Structure
- Study, AD, NA
*Risk↓, *memory↑, *Aβ↓,
5560- betaCar,    β-Carotene: A Natural Compound Improves Cognitive Impairment and Oxidative Stress in a Mouse Model of Streptozotocin-Induced Alzheimer's Disease
- in-vivo, AD, NA
*cognitive↑, *AChE↓, *Aβ↓,
4080- betaCar,    Vitamin A and Alzheimer's disease
- Review, AD, NA
*antiOx↑, *cognitive↑, *Aβ↓,
3693- BM,    Bacopa monnieri prevents colchicine-induced dementia by anti-inflammatory action
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *BACE/β-secretase↓, *Inflam↓, *ROS↓, *antiOx↑,
3692- BM,    Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer's disease
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *Aβ↓, *cognitive↑,
5656- BNL,    Role of borneol as enhancer in drug formulation: A review
- Review, Nor, NA - Review, Stroke, NA - Review, AD, NA
*eff↑, BBB↑, ChemoSen↑, *Inflam↓, *NO↓, *TNF-α↓, *IL6↓, *Bacteria↓, *eff↑, *Aβ↓, *SOD↑, *neuroP↑, *EPR↑, toxicity↓, P-gp/ABCB1↓, eff↑, other↝,
5663- BNL,    Osthole/borneol thermosensitive gel via intranasal administration enhances intracerebral bioavailability to improve cognitive impairment in APP/PS1 transgenic mice
- in-vivo, AD, NA
*ZO-1↓, *cl‑Casp3↓, *Bax:Bcl2↓, *MDA↓, *Apoptosis↓, *Aβ↓, *BACE/β-secretase↓, *cognitive↑, *BioAv↑, memory↑, P-gp/ABCB1↓, BioEnh↑,
3785- Bor,    Discovery of boron-containing compounds as Aβ aggregation inhibitors and antioxidants for the treatment of Alzheimer's disease
- Analysis, AD, NA
*Aβ↓, *antiOx↑, *IronCh↑, *PDE4↓,
760- Bor,    Therapeutic Efficacy of Boric Acid Treatment on Brain Tissue and Cognitive Functions in Rats with Experimental Alzheimer’s Disease
- in-vivo, AD, NA
*memory↑, *ROS↓, *GSH↑, *Aβ↓, *Inflam↓, *MMP↑, *lipid-P↓, *Ca+2↓, *cognitive↑, *TOS↓,
4270- Bos,    Boswellic acids ameliorate neurodegeneration induced by AlCl3: the implication of Wnt/β-catenin pathway
- in-vivo, AD, NA
*memory↑, *AChE↓, *Aβ↓, *TNF-α↓, *IL1β↓, *lipid-P↓, *TAC↑, *BDNF↑, *β-catenin/ZEB1↑, *Dose↑,
3866- Bos,    Mechanistic role of boswellic acids in Alzheimer's disease: Emphasis on anti-inflammatory properties
- Review, AD, NA
*neuroP↑, *Inflam↓, *AChE↓, *Ach↑, *NRF2↑, *NF-kB↓, *Aβ↓,
6542- BSB,    Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol
- Review, Var, NA - Review, Park, NA - Review, AD, NA
AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2/PTGS2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE/β-secretase↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2/PTGS2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL6↑, *MMP13↓,
6552- BSB,    Biochemical characterization of chamomile essential oil: Antioxidant, antibacterial, anticancer and neuroprotective activity and potential treatment for Alzheimer's disease
- in-vivo, AD, NA
*TNF-α↓, *Aβ↓, *Casp3↓, *Bcl-2↓, *neuroP↑, *antiOx↑, *Inflam↓, *AntiBio↑, *AChE↓, *BChE↓, Dose↝, Dose↝, Dose↝,
4263- CA,    Neuroprotective Effects of Carnosic Acid: Insight into Its Mechanisms of Action
- Review, AD, NA
*neuroP↑, *ROS↓, *NO↓, *COX2/PTGS2↓, *MAPK↓, *NRF2↑, *GSH↑, *HO-1↑, *5HT↑, *BDNF↑, *PI3K↑, *Akt↑, *NF-kB↑, *BBB↑, *SIRT1↑, *memory↑, *Aβ↓, *NLRP3↓,
7516- CA,    Caffeic Acid, a Polyphenolic Micronutrient Rescues Mice Brains against Aβ-Induced Neurodegeneration and Memory Impairment
- in-vivo, AD, NA
*neuroP↑, *antiOx↑, *memory↑, *Learn↑, *cognitive↑, *ROS↓, *lipid-P↓, *NRF2↑, *HO-1↑, *Aβ↓, *BACE/β-secretase↓,
5756- CA,    Experimental Evidence of Caffeic Acid’s Neuroprotective Activity in Alzheimer’s Disease: In Vitro, In Vivo, and Delivery-Based Insights
- vitro+vivo, AD, NA
*neuroP↑, *antiOx↑, *Inflam↓, *AChE↓, *BChE↓, *cognitive↑, *ROS↓, *Aβ↓, *tau↓, eff↑,
5860- CAP,    Beneficial Effects of Capsaicin in Disorders of the Central Nervous System
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *memory↑, *Pain↓, *TRPV1↑, *Aβ↓, *tau↓, *cognitive↑, *Risk↓, *motorD↓, *ROS↓, *TNF-α↓, *IL1β↓, *eff↑, *Risk↓,
5858- CAP,    Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health
- Review, Nor, NA - Review, AD, NA
*BBB↓, *GutMicro↑, Obesity↓, *Inflam↓, *AntiCan↑, *TRPV1↑, *Ca+2↑, *antiOx↑, *cardioP↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↑, *neuroP↑, Apoptosis↑, p38↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, TRIB3↑, NADH↓, SIRT1↓, TumCG↓, TumCMig↓, TOP1↓, TOP2↓, β-catenin/ZEB1↓, *ROS↓, *Aβ↓,
3854- CAP,    Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice
- in-vivo, AD, NA
*Aβ↓, *cognitive↑, *APP↓, *MMP-10↝, *p‑tau↓, *Inflam↓, *neuroP↑, *Risk↓, *TNF-α↓, *IFN-γ↓, *IL6↓, *PPARα↑,
3855- CAP,    Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice
- in-vivo, AD, NA
*Risk↓, *Aβ↓, *p‑tau↓, *Inflam↓, *neuroP↑, *cognitive↑, *ADAM10↑, *PPARα↑,

Showing Research Papers: 1 to 50 of 343
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 343

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

3MST/MPST↑, 1,   AKR1B1/ALR2↑, 1,   AKR1B10↝, 1,   AKR1C3/17β-HSD5/PGF Synthase↑, 1,   AntiBio↑, 7,   Ast↓, 1,   autophagy↓, 1,   Aβ42↓, 5,   CBS↑, 1,   CHRM1↑, 1,   compII↑, 1,   DA↑, 1,   GFAP↓, 2,   GlyFlow↑, 1,   IRes↓, 1,   IRes↑, 1,   Learn↑, 8,   MEF2D↑, 1,   MGlio↓, 1,   miR-107↑, 1,   NA↝, 1,   NeuroI↓, 8,   NMDAR↑, 1,   RT↓, 1,   SNAP25↑, 1,   Stroke↓, 5,   SYN1↑, 1,   SYT1↑, 1,   TREM2↓, 1,   TRPA1↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 1,   antiOx↓, 4,   antiOx↑, 118,   ARE↑, 2,   ARE↝, 1,   Bil↑, 2,   Catalase↓, 1,   Catalase↑, 41,   Copper↓, 1,   Fenton↓, 2,   Ferroptosis↓, 3,   GCLC↑, 2,   GCLM↑, 2,   GPx↓, 1,   GPx↑, 24,   GPx4↑, 1,   GSH↓, 1,   GSH↑, 41,   GSR↑, 7,   GSSG↓, 2,   GSTs↓, 1,   GSTs↑, 8,   H2O2↓, 5,   HDL↓, 1,   HDL↑, 2,   HNE↓, 2,   HO-1↓, 1,   HO-1↑, 36,   HO-1⇅, 1,   HO-2↓, 1,   hyperG↓, 1,   Iron↓, 1,   Iron↝, 1,   Keap1↓, 2,   Keap1↑, 2,   lipid-P↓, 54,   lipid-P↑, 1,   MDA↓, 36,   MDA↑, 1,   MFN2↑, 1,   MPO↓, 4,   NOX4↓, 1,   NQO1↑, 8,   Nrf1↑, 2,   NRF2↓, 3,   NRF2↑, 51,   NRF2↝, 1,   OXPHOS↑, 1,   PARK2↑, 4,   RNS↓, 1,   ROS?, 1,   ROS↓, 180,   ROS↑, 2,   mt-ROS↓, 2,   SAM-e↓, 1,   selenoP↑, 1,   SIRT3↑, 5,   SOD↓, 1,   SOD↑, 56,   mt-SOD↑, 1,   SOD1↑, 2,   TAC↑, 7,   TBARS↓, 1,   Thiols↑, 1,   TOS↓, 1,   Trx1↑, 2,   TrxR↑, 2,   uricA↓, 1,   VDAC1↓, 1,   VitC↑, 1,   VitE↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↑, 1,   FTH1↑, 1,   IronCh↑, 15,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 18,   mt-ATP↑, 1,   compIII↑, 1,   DRP1/DNM1L↓, 1,   FIS1↓, 2,   mitResp↑, 3,   MMP↓, 2,   MMP↑, 18,   mtDam↓, 5,   PGC-1α↓, 1,   PGC-1α↑, 6,   PINK1↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   Ac-histone H3↑, 1,   ACC↑, 1,   Acetyl-CoA↓, 1,   Acetyl-CoA↑, 2,   adiP↑, 1,   ALAT↓, 5,   AMPK↑, 14,   p‑AMPK↑, 1,   cAMP↑, 3,   cMyc↓, 1,   CREB↓, 1,   CREB↑, 7,   p‑CREB↑, 4,   FAO↑, 1,   G6PD↑, 1,   glucose↓, 2,   glucose↝, 1,   GlucoseCon↑, 6,   Glycolysis↓, 1,   LDH↓, 4,   LDL↓, 11,   NAD↑, 2,   NADPH↓, 2,   NADPH↑, 3,   PDH↑, 1,   PDKs↓, 1,   PPARα↑, 2,   PPARα↝, 1,   PPARγ↓, 2,   PPARγ↑, 14,   SIRT1↓, 1,   SIRT1↑, 13,  

Cell Death(tgid=5) ⓘ

Akt↓, 4,   Akt↑, 13,   Akt↝, 1,   p‑Akt↓, 4,   p‑Akt↑, 3,   Apoptosis↓, 28,   ASK1↓, 1,   BAD↓, 1,   BAX↓, 10,   BAX↑, 2,   Bax:Bcl2↓, 2,   Bax:Bcl2↝, 1,   Bcl-2↓, 4,   Bcl-2↑, 9,   Casp↓, 2,   Casp12↓, 1,   Casp3↓, 16,   Casp3↑, 2,   cl‑Casp3↓, 2,   Casp6↓, 1,   Casp8↓, 1,   Casp9↓, 5,   Casp9↑, 1,   cl‑Casp9↓, 1,   Cyt‑c↓, 3,   Ferroptosis↓, 3,   GranB/GZMB↓, 1,   iNOS↓, 25,   iNOS↑, 1,   JNK↓, 6,   JNK↑, 1,   p‑JNK↓, 4,   MAPK↓, 10,   MAPK↑, 3,   p‑MAPK?, 1,   p‑MAPK↓, 1,   MCT1↓, 1,   necrosis↓, 1,   p38↓, 3,   p‑p38↓, 3,   TRPV1↑, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 22,   AntiThr↑, 1,   cJun↓, 1,   H3↑, 1,   H4↑, 1,   HATs↓, 1,   other?, 1,   other↓, 1,   other↑, 14,   other↝, 13,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 3,   eIF2α↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 7,   GRP78/BiP↓, 4,   GRP78/BiP↑, 1,   HSF1↑, 2,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 5,   HSP90↑, 1,   HSPs↑, 1,   HSPs↝, 1,   IRE1↓, 1,   PERK↓, 1,   UPR↑, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 3,   DYRK1A↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B↑, 2,   LC3II↓, 1,   lysosome↑, 1,   MitoP↑, 5,   p62↓, 3,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 5,   DNMT1↓, 2,   DNMT3A↑, 1,   P53↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

cFos↑, 1,   CHIP↑, 1,   ERK↓, 3,   ERK↑, 6,   p‑ERK↓, 1,   p‑ERK↑, 3,   FGF↑, 1,   FOXO3↑, 2,   GSK‐3β↓, 18,   p‑GSK‐3β↓, 1,   p‑GSK‐3β↑, 1,   HDAC↓, 1,   HDAC↑, 1,   HDAC1↓, 2,   HDAC2↓, 1,   HDAC3↓, 2,   IGF-1↑, 1,   mTOR↓, 10,   mTOR↑, 1,   p‑mTOR↑, 1,   neuroG↑, 6,   P70S6K↓, 1,   PI3K↓, 5,   PI3K↑, 8,   p‑PI3K↓, 1,   PTEN↑, 1,   Src↓, 1,   STAT3↓, 1,   p‑STAT3↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 5,   AntiAg↑, 4,   AP-1↓, 2,   APP↓, 21,   APP∅, 2,   cl‑APP↓, 1,   ARG1/2↑, 1,   Ca+2?, 1,   Ca+2↓, 18,   Ca+2↑, 1,   Ca+2↝, 1,   cal2↓, 1,   Cartilage↑, 1,   CD31/PECAM-1↑, 2,   CDK5↓, 2,   Ki-67↑, 1,   LRP1↑, 3,   MMP-10↓, 1,   MMP-10↝, 1,   MMP1↓, 1,   MMP13↓, 1,   MMP2↑, 1,   MMP9↓, 8,   MMP9↑, 1,   MMPs↓, 2,   MUC1↑, 1,   N-cadherin↑, 2,   PKA↑, 3,   PKCδ↑, 1,   p‑PKCδ↑, 1,   PTP1B↓, 1,   RAGE↓, 2,   Rho↓, 1,   p‑SMAD2↓, 1,   SPARC↓, 1,   p‑T-cadherin↓, 1,   TG2/TGase↓, 1,   TGF-β↓, 3,   TGF-β↑, 1,   TGF-β1↑, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TJ↑, 1,   TRPC1↓, 1,   TumCI↓, 1,   TumCP↓, 1,   TXNIP↓, 2,   Tyro3↓, 1,   VCAM-1↓, 4,   Vim↓, 1,   ZO-1↓, 2,   β-catenin/ZEB1↑, 3,   β-catenin/ZEB1↝, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 1,   ATF4↓, 2,   CLDN5↓, 1,   EPR↑, 1,   Hif1a↓, 1,   Hif1a↑, 1,   NO↓, 16,   NO↑, 2,   VEGF↓, 2,   VEGF↑, 4,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   AQPs↑, 1,   pol-AQPs↑, 1,   BBB?, 1,   BBB↓, 3,   BBB↑, 63,   BBB↝, 3,   BBB∅, 2,   GastroP↑, 4,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↑, 1,   IBI↑, 3,   OCLN↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 3,   COX2/PTGS2↓, 34,   CRP↓, 2,   CTSZ↓, 1,   CTSZ↝, 1,   HMGB1↓, 1,   ICAM-1↓, 2,   IFN-γ↓, 5,   p‑IKKα↓, 1,   IL1↓, 1,   IL10↓, 3,   IL10↑, 9,   IL12↓, 1,   IL17↓, 4,   IL1α↓, 1,   IL1β↓, 49,   IL1β↑, 1,   IL2↓, 3,   IL23↓, 2,   IL33↓, 1,   IL4↓, 2,   IL4↑, 4,   IL6↓, 36,   IL6↑, 2,   IL8↓, 3,   Imm↑, 7,   Imm⇅, 1,   Inflam?, 1,   Inflam↓, 158,   Inflam↑, 1,   Inflam∅, 2,   p‑IκB↓, 1,   LPS↓, 2,   LTA/TNF-β↓, 1,   MCP1/CCL2↓, 6,   MIP‑1α/CCL3↓, 1,   MyD88↓, 4,   NF-kB↓, 53,   NF-kB↑, 1,   p‑NF-kB↓, 3,   p‑p65↓, 2,   PGE2↓, 9,   RANTES↓, 1,   TLR2↓, 4,   TLR3↓, 1,   TLR4↓, 11,   TNF-α↓, 66,   TRIF↓, 2,  

Cellular Microenvironment(tgid=17) ⓘ

NOX↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 7,   AChE↓, 68,   AChE↝, 1,   AChE∅, 1,   ADAM10↑, 5,   ADAM10↝, 1,   BChE↓, 11,   BChE∅, 1,   BDNF↓, 1,   BDNF↑, 36,   BDNF∅, 2,   BrainVol∅, 1,   ChAT↑, 12,   GABA↓, 3,   GABA↑, 3,   GABA↝, 1,   MAOA↓, 6,   MAOA↑, 1,   monoA↑, 2,   NGF↑, 3,   PSD95?, 1,   PSD95↑, 4,   tau?, 1,   tau↓, 33,   p‑tau↓, 60,   TrkB↑, 4,   TrkB↝, 1,  

Protein Aggregation(tgid=19) ⓘ

AEP↓, 1,   AGEs↓, 4,   Aβ?, 1,   Aβ↓, 331,   Aβ↑, 3,   Aβ∅, 6,   BACE/β-secretase↓, 52,   BACE/β-secretase↑, 1,   BACE/β-secretase↝, 1,   IDE↑, 3,   MAOB↓, 3,   NEP↑, 1,   NLRP3↓, 21,   PP2A↑, 5,   XO↓, 2,   β-Amyloid↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

cortisol↓, 1,   ER(estro)↓, 1,   ER(estro)↑, 2,   ERβ/ESR2↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 21,   BioAv↑, 45,   BioAv↝, 13,   ChemoSen↑, 1,   DDS↑, 3,   Dose↓, 2,   Dose↑, 4,   Dose↝, 44,   eff↓, 1,   eff↑, 49,   Half-Life?, 1,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 7,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 5,   Albumin↑, 1,   AST↓, 5,   Bil↑, 2,   BloodF↑, 4,   BMD↑, 2,   BP↓, 6,   BP∅, 1,   Calcium↝, 2,   creat↓, 2,   CRP↓, 2,   Ferritin↑, 1,   GutMicro↑, 24,   Hcy/homoC↓, 3,   HemoG↑, 1,   IL6↓, 36,   IL6↑, 2,   Ki-67↑, 1,   LDH↓, 4,   NOS2↓, 1,   RAGE↓, 2,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 4,   antiAll↑, 1,   AntiArt↑, 3,   AntiCan↑, 9,   AntiDiabetic↑, 8,   antiPs↑, 1,   ANXi↓, 2,   cardioP?, 1,   cardioP↑, 30,   chemoP↑, 1,   cognitive↓, 2,   cognitive↑, 170,   cognitive↝, 1,   cognitive∅, 4,   hepatoP↑, 22,   memory↓, 1,   memory↑, 141,   memory∅, 3,   Mood↑, 5,   motorD↓, 1,   motorD↑, 15,   neuroP↑, 179,   neuroP↝, 1,   Obesity↓, 8,   OS↑, 6,   Pain↓, 3,   PDE4↓, 1,   radioP↑, 4,   RenoP↑, 10,   Risk↓, 12,   Sleep↑, 1,   STEP↓, 1,   Strength↑, 5,   toxicity?, 1,   toxicity↓, 22,   toxicity↑, 1,   toxicity↝, 2,   toxicity∅, 3,   Weight∅, 1,   Wound Healing↑, 4,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 3,   AntiViral↑, 4,   Bacteria↓, 9,   CD8+↑, 1,   IRF3↓, 4,   Sepsis↓, 2,  
Total Targets: 520

Scientific Paper Hit Count for: Aβ, Aβ aggregation
19 Selenium NanoParticles
17 Curcumin
14 Resveratrol
14 Ferulic acid
14 Urolithin
12 Magnetic Fields
9 EGCG (Epigallocatechin Gallate)
9 Emodin
8 Berberine
8 Chlorogenic acid
8 Thymoquinone
7 Alpha-Lipoic-Acid
7 Mung Bean Sprouts
7 Hydrogen Gas
7 Luteolin
7 Quercetin
7 Rosmarinic acid
6 Rutin
6 Folic Acid, Vit B9
6 EMF
5 isoquercitrin
5 Ashwagandha(Withaferin A)
5 Carnosine
5 Crocetin
5 Magnetic Field Rotating
5 Mushroom Lion’s Mane
5 Sulforaphane (mainly Broccoli)
4 Apigenin (mainly Parsley)
4 Capsaicin
4 Cinnamon
4 Ginseng
4 Hyperoside
4 Lycopene
4 Silymarin (Milk Thistle) silibinin
4 Vitamin B1/Thiamine
3 beta-carotene(VitA)
3 Cichoric acid / Chicoric acid
3 Fisetin
3 Flickering Light Stimulation
3 Honokiol
3 HydroxyTyrosol
3 isoorientin
3 Kaempferol
3 Licochalcone A
3 Radio Frequency
3 Vitamin B3,Niacin
3 Vitamin B5,Pantothenic Acid
3 Vitamin D3
3 Vitamin K2
2 Aromatherapy
2 Huperzine A/Huperzia serrata
2 Bacopa monnieri
2 borneol
2 Boron
2 Boswellia (frankincense)
2 α-Bisabolol / Chamomile oil
2 Caffeic acid
2 Centella asiatica / Gotu kola → asiaticoside
2 Choline
2 Echinacea
2 Vitamin E
2 diet Short Term Fasting
2 D-limonene
2 Eugenol
2 Angelica archangelica / Garden Angelica
2 Ginkgo biloba
2 Ginkgetin
2 hydrogen sulfide
2 Isobavachalcone
2 Isovitexin
2 Magnolol
2 MCToil
2 Moringa oleifera
2 chitosan
2 Taurine
1 1,8-Cineole
1 Annona atemoya Leaf Extract
1 Anthocyanins
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Astaxanthin
1 Carnosic acid
1 Celastrol
1 Chrysin
1 Coenzyme Q10
1 Rivastigmine
1 Galantamine
1 Cysteamine
1 Date Fruit Extract
1 diet Fermented Foods
1 Ginkgo biloba-EGb 761
1 Phosphatidylserine
1 flavonoids
1 Exercise
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Iron
1 Gallic acid
1 Ginkgolide B
1 Oleuropein
1 Isoliquiritigenin
1 isoflavones
1 Morin
1 Lutein
1 Zeaxanthin
1 Vitexin
1 Magnesium
1 Methylsulfonylmethane
1 Myricetin
1 Nimbolide
1 Protocatechuic acid
1 Piperine
1 Piperlongumine
1 Salvia officinalis
1 S-adenosyl-L-methionine
1 Carvacrol
1 Sesame seeds and Oil
1 Silicic Acid
1 Spermidine
1 Ursolic acid
1 Vanillic Acid
1 Vitamin A, Retinoic Acid
1 Vitamin B12
1 Vitamin B2,Riboflavin
1 probiotics
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1333  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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