Database Query Results : , , AEP

AEP, Asparagine Endopeptidase: Click to Expand ⟱
Source:
Type:
AEP, Asparagine Endopeptidase
-Cleaves APP/Tau into neurotoxic fragments
-upregulated in aging and AD brains
-Cleaves APP and Tau, producing neurotoxic fragments that promote Aβ deposition and Tau aggregation
-AEP inhibitors are being studied as potential neuroprotective agents in AD.
Scientific Papers found: Click to Expand⟱
3835- Moringa,    Moringa Oleifera Alleviates Aβ Burden and Improves Synaptic Plasticity and Cognitive Impairments in APP/PS1 Mice
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *AChE↓, *neuroP↑, *Mood↑, *cognitive↑, *memory↑, *Aβ↓, *BACE↓, *AEP↓, *IDE↑, *NEP↑, *LRP1↑, *PSD95↑, *STEP↓, *APP↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Results for Effect on Normal Cells:
AChE↓,1,   AEP↓,1,   antiOx↑,1,   APP↓,1,   Aβ↓,1,   BACE↓,1,   cognitive↑,1,   IDE↑,1,   Inflam↓,1,   LRP1↑,1,   memory↑,1,   Mood↑,1,   NEP↑,1,   neuroP↑,1,   PSD95↑,1,   STEP↓,1,  
Total Targets: 16

Scientific Paper Hit Count for: AEP, Asparagine Endopeptidase
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1363  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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