Database Query Results : , , IDE

IDE, Insulin-Degrading Enzyme: Click to Expand ⟱
Source:
Type:
IDE, Insulin-Degrading Enzyme
-Reduced IDE activity in AD contributes to Aβ accumulation.
-Enhancing IDE activity or expression may reduce Aβ burden.
Scientific Papers found: Click to Expand⟱
4302- Gins,    Panax ginseng: A modulator of amyloid, tau pathology, and cognitive function in Alzheimer's disease
- Review, AD, NA
*neuroP↑, *Aβ↓, *p‑tau↓, *cognitive↑, *eff↑, *PKA↑, *CREB↑, *BACE↓, *ADAM10↑, *MAPK↑, *ERK↑, *PI3K↑, *Akt↑, *NRF2↑, *PPARγ↓, *IDE↑, *APP↓, *PP2A↑, *memory↑,
3835- Moringa,    Moringa Oleifera Alleviates Aβ Burden and Improves Synaptic Plasticity and Cognitive Impairments in APP/PS1 Mice
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *AChE↓, *neuroP↑, *Mood↑, *cognitive↑, *memory↑, *Aβ↓, *BACE↓, *AEP↓, *IDE↑, *NEP↑, *LRP1↑, *PSD95↑, *STEP↓, *APP↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Results for Effect on Normal Cells:
AChE↓,1,   ADAM10↑,1,   AEP↓,1,   Akt↑,1,   antiOx↑,1,   APP↓,2,   Aβ↓,2,   BACE↓,2,   cognitive↑,2,   CREB↑,1,   eff↑,1,   ERK↑,1,   IDE↑,2,   Inflam↓,1,   LRP1↑,1,   MAPK↑,1,   memory↑,2,   Mood↑,1,   NEP↑,1,   neuroP↑,2,   NRF2↑,1,   PI3K↑,1,   PKA↑,1,   PP2A↑,1,   PPARγ↓,1,   PSD95↑,1,   STEP↓,1,   p‑tau↓,1,  
Total Targets: 28

Scientific Paper Hit Count for: IDE, Insulin-Degrading Enzyme
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1364  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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