Database Query Results : , , MAOA

MAOA, Monoamine Oxidase A: Click to Expand ⟱
Source:
Type: gene/enzyme
Also known as MAO-A, or "Warrior Gene"(associated with increased aggression and impulsivity). This enzyme plays a crucial role in the breakdown of various neurotransmitters, such as serotonin, dopamine, and norepinephrine.
MAOA is commonly overexpressed in prostate cancer, and others.
-MAO-A inhibitors have been proven to be effective antidepressantn
Scientific Papers found: Click to Expand⟱
4280- Api,    Protective effects of apigenin in neurodegeneration: An update on the potential mechanisms
- Review, AD, NA - Review, Park, NA
*neuroP↑, *antiOx↑, *ROS↓, *Inflam↓, *TNF-α↓, *IL1β↓, *PI3K↑, *Akt↑, *BBB↑, *NRF2↑, *SOD↑, *GPx↑, *MAPK↓, *Catalase↑, *HO-1↑, *COX2↓, *PGE2↓, *PPARγ↑, *TLR4↓, *GSK‐3β↓, *Aβ↓, *NLRP3↓, *BDNF↑, *TrkB↑, *GABA↑, *AChE↓, *Ach↑, *5HT↑, *cognitive↑, *MAOA↓,
3684- BBR,    Neuroprotective effects of berberine in animal models of Alzheimer’s disease: a systematic review of pre-clinical studies
- Review, AD, NA
*Inflam↓, *antiOx↓, *AChE↓, *BChE↓, *MAOA↓, *MAOB↓, *lipid-P↓, *GSH↑, *ROS↓, *APP↓, *BACE↓, *p‑tau↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *MAPK↓, *PI3K↓, *Akt↓, *neuroP↑, *memory↑,
3677- BBR,    Berberine: A Potential Multipotent Natural Product to Combat Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *AChE↓, *BChE↓, *MAOA↓, *Aβ↓, *LDL↓, *ROS↓, *RNS↓, *lipid-P↓, *Dose↝, *MAOB↓, *memory↑, *toxicity↓, *BBB↑,
3635- Croc,    A Review of Potential Efficacy of Saffron (Crocus sativus L.) in Cognitive Dysfunction and Seizures
- Review, NA, NA
*memory↑, *cognitive↑, *BioAv↑, *ROS↓, *IL1↓, *TNF-α↓, *NF-kB↓, *neuroP↑, *lipid-P↓, *Thiols↑, *antiOx↑, *AChE↓, *MAOA↝, *SIRT1↑, *PGC-1α↑, *Ach↑,
3637- Croc,    Investigation of the neuroprotective action of saffron (Crocus sativus L.) in aluminum-exposed adult mice through behavioral and neurobiochemical assessment
- NA, AD, NA
*cognitive∅, *MAOA↓, *MDA↓, *GSH↑, *AChE↓,
1616- CUR,  EA,    Kinetics of Inhibition of Monoamine Oxidase Using Curcumin and Ellagic Acid
- in-vitro, Nor, NA
*MAOA↓, *Dose∅, Dose?,
140- CUR,    Curcumin inhibits cancer-associated fibroblast-driven prostate cancer invasion through MAOA/mTOR/HIF-1α signaling
- in-vitro, Pca, PC3
CAFs/TAFs↓, EMT↓, ROS↓, CXCR4↓, IL6↓, MAOA↓, mTOR↓, HIF-1↓,
3943- Shank,    Protective Mechanisms of Nootropic Herb Shankhpushpi (Convolvulus pluricaulis) against Dementia: Network Pharmacology and Computational Approach
- Review, AD, NA
*neuroP↑, *memory↑, *other↝, *AChE↓, *MAOA↓, *MAOB↓, *TrkB↓, *tau↓, *APP↓, *ROS↓, *Mood↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8

Results for Effect on Normal Cells:
5HT↑,1,   Ach↑,2,   AChE↓,6,   Akt↓,1,   Akt↑,1,   antiOx↓,1,   antiOx↑,3,   APP↓,2,   Aβ↓,2,   BACE↓,1,   BBB↑,2,   BChE↓,2,   BDNF↑,1,   BioAv↑,1,   Catalase↑,1,   cognitive↑,2,   cognitive∅,1,   COX2↓,1,   Dose↝,1,   Dose∅,1,   GABA↑,1,   GPx↑,1,   GSH↑,2,   GSK‐3β↓,1,   HO-1↑,1,   IL1↓,1,   IL1β↓,2,   Inflam↓,2,   LDL↓,1,   lipid-P↓,3,   MAOA↓,6,   MAOA↝,1,   MAOB↓,3,   MAPK↓,2,   MDA↓,1,   memory↑,4,   Mood↑,1,   neuroP↑,4,   NF-kB↓,2,   NLRP3↓,1,   NRF2↑,1,   other↝,1,   PGC-1α↑,1,   PGE2↓,1,   PI3K↓,1,   PI3K↑,1,   PPARγ↑,1,   RNS↓,1,   ROS↓,5,   SIRT1↑,1,   SOD↑,1,   tau↓,1,   p‑tau↓,1,   Thiols↑,1,   TLR4↓,1,   TNF-α↓,3,   toxicity↓,1,   TrkB↓,1,   TrkB↑,1,  
Total Targets: 59

Scientific Paper Hit Count for: MAOA, Monoamine Oxidase A
2 Berberine
2 Crocetin
2 Curcumin
1 Apigenin (mainly Parsley)
1 Ellagic acid
1 Shankhpushpi
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:472  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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