cognitive Cancer Research Results

cognitive, cognitive: Click to Expand ⟱
Source:
Type:
Cognitive


Scientific Papers found: Click to Expand⟱
6864- ,    Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment
- Trial, AD, NA
*Risk↑, *cognitive↝,
4051- ,    Long-term association of food and nutrient intakes with cognitive and functional decline: a 13-year follow-up study of elderly French women
- Study, AD, NA
*cognitive↑, *neuroP↑, *other↝, *other⇅,
4039- ,    Association of vitamin B12 deficiency in a dementia cohort with hippocampal atrophy on MRI
- Study, AD, NA
*cognitive↑, *memory↑, *Mood↑,
5303- 5-HTP,    cognitive-support-spore-study/">5-HTP shows early promise for cognitive support and in seniors: Singapore study
- Trial, AD, NA
*cognitive↑, *Dose↝, *5HT↑,
5297- 5-HTP,    Targeting 5-HT Is a Potential Therapeutic Strategy for Neurodegenerative Diseases
- in-vivo, AD, NA - in-vivo, Park, NA
*other↝, *cognitive↑, *memory↑, *Ach↑,
5292- 5-HTP,    Past, present, and future of serotonin-targeting therapeutics for Alzheimer’s disease: Perspectives from DNA methylation
- Review, AD, NA
*other↝, *cognitive↝,
5288- 5-HTP,    The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
- Trial, AD, NA
*5HT↑, *cognitive↑, *BBB↑, *Mood↑,
5306- 5-HTP,    Tryptophan-enriched diet or 5-hydroxytryptophan supplementation given in a randomized controlled trial impacts social cognition on a neural and behavioral level
- Trial, AD, NA
*cognitive↑, *Dose↝,
3940- 5HT,    Role of serotonin in Alzheimer's disease: a new therapeutic target?
- Review, AD, NA
*cognitive↑,
3941- 5HT,  dietMed,  VitB12,  FA,  VitC  Nutrition strategies that improve cognitive function
- Review, AD, NA
*other↑, *other↓, *cognitive↑, *eff↑, *eff↑,
3970- ACNs,    Anthocyanin-rich blueberry extracts and anthocyanin metabolite protocatechuic acid promote autophagy-lysosomal pathway and alleviate neurons damage in in vivo and in vitro models of Alzheimer's disease
- in-vivo, AD, NA
*cognitive↑, *LDH↓, *ROS↓, *neuroP↑,
3968- ACNs,    Enhanced Neuronal Activation with Blueberry Supplementation in Mild Cognitive Impairment
- Human, AD, NA
*BOLD↑, *cognitive?, *eff↑,
3969- ACNs,    Blueberry Supplementation in Midlife for Dementia Risk Reduction
- Human, AD, NA
*memory↑, *cognitive↑, *ROS↓,
3971- ACNs,    Blueberry Supplementation Improves Memory in Older Adults
- Human, AD, NA
*antiOx↑, *Inflam↓, *memory↑, *neuroP↑, *cognitive↑, *Mood↑, *glucose↓,
3972- ACNs,    Recent Research on the Health Benefits of Blueberries and Their Anthocyanins
- Review, AD, NA - Review, Park, NA
*cardioP↑, *neuroP↑, *Inflam↓, *antiOx↓, *GutMicro↑, *Half-Life↑, *LDL↓, *adiP↓, *HDL↑, *CRP↓, *IL1β↓, *Risk↓, *Risk↓, *cognitive↑, *memory↑, *other↑, *BOLD↑, *NO↓, *MDA↓, *GSH↑, *VitC↑, *SOD↑, *GPx↑, *eff↓, *eff↓, *eff↓, *eff↝, *Risk↓,
3865- ACNs,    Consumption of anthocyanin-rich cherry juice for 12 weeks improves memory and cognition in older adults with mild-to-moderate dementia
- Human, AD, NA
*memory↑, *BP↓, *cognitive↑,
3864- ACNs,    Anthocyanins Potentially Contribute to Defense against Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *Aβ↓, *ROS↓, *cognitive↑, *APP↓, *BBB↑, *Ca+2↓, *ATP↑, *BACE/β-secretase↓, *p‑NF-kB↓, *TNF-α↓, *iNOS↓,
4163- ACNs,  Flav,    Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor
- in-vivo, AD, NA
memory↑, *BDNF↑, *cognitive↑,
5355- AL,    Mini-review: The health benefits and applications of allicin
- Review, Var, NA
*BioAv↑, *cardioP↑, *hepatoP↑, *RenoP↑, *Half-Life↝, *BioAv↓, *neuroP↑, *cognitive↑, *ROS↓, *lipid-P↓, *DNArepair↑, *ChemoSen↑,
6763- AL,    Revealing the Therapeutic Uses of Garlic (Allium sativum) and Its Potential for Drug Discovery
- Review, Nor, NA
*Inflam↓, *AntiBio↑, *AntiDiabetic↑, *hepatoP↑, *antiOx↑, *AntiFungal↑, *Wound Healing↑, *other↑, *BP↓, *LDL↓, *AntiAg↑, *cognitive↑, *memory↑, Risk↑, *COX1↓, *TXA2↓,
236- AL,    Allicin: Chemistry and Biological Properties
- Analysis, NA, NA
GSH↓, Bacteria↓, LDL↓, ROS↑, NRF2↑, cognitive↑, memory↑, BP↓, RNS↓,
2558- AL,    Allicin, an Antioxidant and Neuroprotective Agent, Ameliorates Cognitive Impairment
- Review, AD, NA
*AntiCan↑, *antiOx↑, *cardioP↑, *neuroP↑, cognitive↑, *ROS↓, *NOX↓, *TLR4↓, *NF-kB↓, *JNK↓, *AntiAg↑, *H2S↑, *BP↓, Telomerase↓, *Insulin↑, BioAv↝, *GSH↑, *Catalase↑,
2657- AL,    Allicin pharmacology: Common molecular mechanisms against neuroinflammation and cardiovascular diseases
- Review, CardioV, NA - Review, AD, NA
*Inflam↓, *antiOx↑, *neuroP↑, *cardioP↑, *AntiTum↑, *mtDam↑, *HSP70/HSPA5↑, *NRF2↑, *RAAS↓, *cognitive↑, *SOD↑, *ROS↓, *NRF2↑, *ER Stress↓, *neuroP↑, *memory↑, *TBARS↓, *MPO↓, *SOD↑, *GSH↑, *iNOS↓, *p‑eNOS↑, *HO-1↑,
2660- AL,    Allicin: A review of its important pharmacological activities
- Review, AD, NA - Review, Var, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2/PTGS2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2/KDR/Flk1↓, p‑FAK↓,
3269- ALA,    Sulfur-containing therapeutics in the treatment of Alzheimer’s disease
- NA, AD, NA
*AChE↓, *GlucoseCon↑, *ACC↑, *GSH↑, *Aβ↓, *Catalase↑, *GSR↑, *GSTs↑, *NADPH↑, *NQO1↑, *iNOS↓, *NF-kB↓, *lipid-P↓, *BBB↑, *memory↑, *cognitive↑, *antiOx↑, *Inflam↓,
3270- ALA,    Alpha-lipoic acid as a new treatment option for Alzheimer's disease--a 48 months follow-up analysis
- Trial, AD, NA
*cognitive↑, *other↝, *neuroP↑, *IronCh↑, *ROS↓, *GSH↑,
3271- ALA,    Decrypting the potential role of α-lipoic acid in Alzheimer's disease
- Review, AD, NA
*antiOx↑, *memory↑, *neuroP↑, *Inflam↓, *IronCh↑, *NRF2↑, *BBB↑, *GlucoseCon↑, *Ach↑, *ROS↓, *p‑tau↓, *Aβ↓, *cognitive↑, *Hif1a↑, *Ca+2↓, *GLUT3↑, *GLUT4↑, *HO-1↑, *VEGF↑, *PDKs↓, *PDH↑, *VCAM-1↓, *GSH↑, *NRF2↑, *hepatoP↑, *ChAT↑,
3272- ALA,    Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
- Review, AD, NA
*antiOx↑, *glucose↑, *eNOS↑, *NRF2↑, *MMP9↓, *VCAM-1↓, *NF-kB↓, *cardioP↑, *cognitive↑, *eff↓, *BBB↑, *IronCh↑, *GSH↑, *PKCδ↑, *ERK↑, *p38↑, *MAPK↑, *PI3K↑, *Akt↑, *PTEN↓, *AMPK↑, *GLUT4↑, *GLUT1↑, *Inflam↓,
3438- ALA,    The Potent Antioxidant Alpha Lipoic Acid
- Review, NA, NA - Review, AD, NA
*antiOx↑, *cardioP↑, *cognitive↑, *AntiAge↑, *Inflam↓, *AntiCan↑, *neuroP↑, *IronCh↑, *ROS↑, *Weight↓, *Ach↑, *ROS↓, *GSH↑, *lipid-P↓, *memory↑, *NRF2↑, *ChAT↑, *GlucoseCon↑, *Acetyl-CoA↑,
3443- ALA,    Molecular and Therapeutic Insights of Alpha-Lipoic Acid as a Potential Molecule for Disease Prevention
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *IronCh↑, *cognitive↑, *cardioP↓, AntiCan↑, *neuroP↑, *Inflam↓, *BioAv↓, *AntiAge↑, *Half-Life↓, *BioAv↝, other↝, EGFR↓, Akt↓, ROS↓, TumCCA↑, p27/CDKN1B↑, PDH↑, Glycolysis↓, ROS↑, *eff↑, *memory↑, *motorD↑, *GutMicro↑,
3444- ALA,    Alpha-Lipoic Acid Nootropic Review: Benefits, Use, Dosage & Side Effects
- Review, NA, NA
*BBB↑, *cognitive↑, *neuroP↑, *antiOx↑,
3447- ALA,    Redox Active α-Lipoic Acid Differentially Improves Mitochondrial Dysfunction in a Cellular Model of Alzheimer and Its Control Cells
- in-vitro, AD, SH-SY5Y
*ATP↑, *MMP↑, *ROS↓, *GlucoseCon↑, *GSH↑, *neuroP↑, *cognitive↑, *Ach↑, *Inflam↓, *Aβ↓, OXPHOS↓,
3551- ALA,    Alpha lipoic acid treatment in late middle age improves cognitive function: Proteomic analysis of the protective mechanisms in the hippocampus
- in-vivo, AD, NA
*cognitive↑, *Apoptosis↓, *Inflam↓, *antiOx↑, *BioAv↝, *neuroP↑,
3539- ALA,    Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
- Review, AD, NA
*ROS↓, *IronCh↑, *GSH↑, *antiOx↑, *NRF2↑, *MMP9↓, *VCAM-1↓, *NF-kB↓, *cognitive↑, *Inflam↓, *BioAv↝, *BioAv↝, *BBB↑, *H2O2∅, *neuroP↑, *PKCδ↑, *ERK↑, *MAPK↑, *PI3K↑, *Akt↑, *PTEN↓, *AMPK↑, *GLUT4↑, *GlucoseCon↑, *BP↝, *eff↑, *ICAM-1↓, *VCAM-1↓, *Dose↝,
3543- ALA,    The Effect of Lipoic Acid Therapy on Cognitive Functioning in Patients with Alzheimer's Disease
- Study, AD, NA
*cognitive↑, *antiOx↑, *Inflam↓, *neuroP↑, *Ach↑, *ROS↓, *GlucoseCon↑, *lipid-P↓, *GSH↑, *Acetyl-CoA↑,
3552- ALA,    The dietary fatty acids α-linolenic acid (ALA) and linoleic acid (LA) selectively inhibit microglial nitric oxide production
- in-vitro, AD, BV2
*NO↓, *cognitive↑,
3550- ALA,    Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease?
- Review, AD, NA
*antiOx↑, *Inflam↓, *PGE2↓, *COX2/PTGS2↓, *iNOS↓, *TNF-α↓, *IL1β↓, *IL6↓, *BioAv↓, *Ach↑, *ROS↓, *cognitive↑, *neuroP↑, *BBB↑, *Half-Life↓, *BioAv↑, *Casp3↓, *Casp9↓, *ChAT↑, *cognitive↑, *eff↑, *cAMP↑, *IL2↓, *INF-γ↓, *TNF-α↓, *SIRT1↑, *SOD↑, *GPx↑, *MDA↓, *NRF2↑,
3549- ALA,    Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia
- Review, AD, NA
*Inflam↓, *other↝, *other↝, *neuroP↑, *BioAv↝, *adiP↑, *BBB↑, *Casp6↓, *Casp9↓, *TNF-α↓, *IL6↓, *IL1β↓, *ROS↓, *NO↓, *iNOS↓, *COX2/PTGS2↓, *JNK↓, *p‑NF-kB↓, *Aβ↓, *BP↓, *memory↑, *cAMP↑, *ERK↑, *Akt↑, cognitive?,
3547- ALA,    Potential Therapeutic Effects of Lipoic Acid on Memory Deficits Related to Aging and Neurodegeneration
- Review, AD, NA - Review, Park, NA
*memory↑, *neuroP↑, *motorD↑, *VitC↑, *VitE↑, *GSH↑, *SOD↑, *Catalase↑, *GPx↑, *5HT↑, *lipid-P↓, *IronCh↑, *AChE↓, *Inflam↓, *GlucoseCon↑, *GLUT3↑, *GLUT4↑, NF-kB↓, *IGF-1↑, *IL1β↓, *TNF-α↓, *cognitive↑, *ChAT↑, *HO-1↑, *NQO1↑,
3546- ALA,    Cognitive and Mood Effect of Alpha-Lipoic Acid Supplementation in a Nonclinical Elder Sample: An Open-Label Pilot Study
- Study, AD, NA
*antiOx↑, *ROS↓, *cognitive∅, *lipid-P↓, *memory↑, *ChAT↑, *Acetyl-CoA↑, *Aβ↓, *BioAv↑, *BBB↑, *toxicity∅,
3545- ALA,    Potential therapeutic effects of alpha lipoic acid in memory disorders
- Review, AD, NA
*neuroP↑, *Inflam↓, *VCAM-1↓, *5HT↑, *memory↑, *BioAv↝, *Half-Life↓, *NF-kB↓, *antiOx↑, *IronCh↑, *ROS↓, *ATP↑, *ChAT↑, *Ach↑, *cognitive↑, *lipid-P↓, *VitC↑, *VitE↑, *GSH↑, *SOD↑, *Catalase↑, *GPx↑, *Aβ↓,
3544- ALA,    Alpha lipoic acid for dementia
- Review, AD, NA
*antiOx↑, *BBB↑, *VitC↑, *VitE↑, *GSH↑, *IronCh↑, *neuroP↑, *NO↓, *cognitive↑, *AntiAge↑, *memory↑, *ROS↓,
4282- ALA,    Effect of add-on alpha lipoic acid on psychopathology in patients with treatment-resistant schizophrenia: a pilot randomized double-blind placebo-controlled trial
- Trial, NA, NA
*antiOx↑, *Inflam↓, *lipid-P↓, *adiP↑, *cognitive∅, *BDNF↑,
3974- ALC,    Carnitine
- Review, AD, NA
*Dose↝, *cognitive↑,
3975- ALC,    Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease
- Trial, AD, NA
*cognitive↑,
3976- ALC,    Acetyl-L-carnitine for dementia
- Review, AD, NA
*cognitive↝, *Mood↝,
5262- aLinA,    The Role of Alpha-Linolenic Acid and Other Polyunsaturated Fatty Acids in Mental Health: A Narrative Review
- Review, AD, NA
*neuroP↑, *Risk↓, *cognitive↑, *Inflam↓, *antiOx↑, *BDNF↑,
4124- Alum,    The potential influence of silica present in drinking water on Alzheimer's disease and associated disorders
- Review, AD, NA
*cognitive↓,
4130- Alum,    Silica and aluminum in drinking water and cognitive impairment in the elderly
- Study, AD, NA
*cognitive↓,
4132- Alum,    Relation between aluminum concentrations in drinking water and Alzheimer's disease: an 8-year follow-up study
- Study, AD, NA
*Risk↑, *cognitive↓, *BioAv↑,

Showing Research Papers: 1 to 50 of 649
Page 1 of 13 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 649

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

3-NT↓, 1,   AcOH↑, 1,   AIF1/Iba-1↓, 1,   AKR1B1/ALR2↑, 1,   AKR1B10↝, 1,   AKR1C3/17β-HSD5/PGF Synthase↑, 1,   AntiBio↑, 7,   APOE4↓, 1,   autophagy↓, 1,   autophagy↝, 1,   Aβ42↓, 7,   Buty↑, 1,   compII↑, 1,   cough?, 1,   DA↑, 1,   END↑, 1,   FNDC5↑, 1,   GFAP↓, 4,   HRV↑, 1,   Ingr↝, 3,   IRes↑, 1,   Learn?, 1,   Learn↑, 14,   LPAR1/EDG2↑, 1,   MEF2D↑, 1,   NA↝, 1,   NeuroI↓, 7,   PSEN1/PS1↑, 1,   rHR↓, 1,   RT↓, 1,   SCFAs↑, 1,   SNAP25↑, 2,   SoreThr?, 1,   Stress↓, 2,   Stroke↓, 8,   Stroke↑, 1,   SYN1↑, 1,   SYP↑, 1,   SYT1↑, 1,   Tinn↓, 1,   TMAO↑, 4,   TREM2↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 3,   antiOx?, 1,   antiOx↓, 6,   antiOx↑, 146,   mt-antiOx↑, 1,   ARE↑, 3,   Bil↑, 1,   Catalase↓, 2,   Catalase↑, 51,   Copper↓, 1,   Fenton↓, 1,   Ferroptosis↓, 4,   GCLC↑, 1,   GCLM↑, 1,   GPx↓, 1,   GPx↑, 35,   GPx1↑, 2,   GPx4↑, 3,   GSH↑, 66,   GSR↓, 2,   GSR↑, 7,   GSSG↓, 1,   GSTs↓, 1,   GSTs↑, 8,   H2O2↓, 4,   H2O2∅, 1,   HDL↑, 5,   HNE↓, 1,   HNE↑, 1,   HO-1↓, 2,   HO-1↑, 42,   HO-2↓, 1,   Iron↓, 3,   Keap1↓, 1,   Keap1↝, 1,   lipid-P↓, 64,   MDA↓, 52,   MDA↑, 2,   MFN1↝, 1,   MFN2↑, 1,   MFN2↝, 1,   MPO↓, 5,   MPOD↑, 3,   NADH↓, 1,   NQO1↑, 13,   NRF2↓, 4,   NRF2↑, 75,   OXPHOS↑, 1,   PARK2↑, 1,   Prx↓, 1,   Prx↑, 1,   RNS↓, 3,   ROS?, 1,   ROS↓, 222,   ROS↑, 3,   mt-ROS?, 1,   mt-ROS↓, 4,   SAM-e↓, 2,   SAM-e↑, 1,   SIRT3↑, 4,   SOD↓, 2,   SOD↑, 76,   SOD1↑, 3,   SOD2↑, 2,   TAC↑, 8,   TBARS↓, 4,   Thiols↑, 2,   TOS↓, 1,   Trx↑, 1,   Trx1↑, 1,   TrxR↑, 2,   VDAC1↓, 1,   VitC↑, 6,   VitE↑, 3,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↑, 1,   FTL↓, 1,   IronCh↑, 17,   TfR1/CD71↓, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↓, 2,   ATP↑, 20,   ATP↝, 1,   compIII↑, 1,   DRP1/DNM1L↓, 1,   p‑DRP1/DNM1L↝, 1,   FIS1↓, 2,   Insulin↓, 1,   Insulin↑, 2,   mitResp↑, 3,   MMP↑, 16,   mtDam↓, 12,   mtDam↑, 1,   OCR↑, 2,   PGC-1α↑, 9,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 2,   Ac-histone H3↑, 1,   ACC↓, 1,   ACC↑, 1,   Acetyl-CoA↑, 3,   adiP↓, 1,   adiP↑, 3,   AKT1↓, 1,   ALAT?, 1,   ALAT↓, 11,   ALAT∅, 1,   AMPK↑, 17,   p‑AMPK↑, 2,   cAMP↑, 3,   cMyc↓, 1,   CREB↓, 1,   CREB↑, 16,   p‑CREB↑, 4,   CYP3A2↓, 2,   DHA↑, 2,   ECAR↓, 1,   FAO↓, 1,   FASN↓, 1,   FGF21↑, 2,   G6PD↑, 1,   glucose↓, 5,   glucose↑, 1,   GlucoseCon↑, 12,   GlutMet↑, 1,   Glycolysis↓, 2,   Glycolysis↑, 1,   H2S↑, 3,   HK2↑, 1,   KeyT↑, 4,   LDH↓, 11,   LDH↑, 1,   LDL↓, 18,   lipidLev↓, 1,   NAD↑, 2,   NAD↝, 1,   NADPH↓, 3,   NADPH↑, 3,   PDH↑, 1,   PDKs↓, 1,   PFK↓, 1,   PFK↑, 1,   PKM2↑, 1,   PONs↑, 1,   PPARα↑, 6,   PPARγ↓, 1,   PPARγ↑, 10,   SIRT1↑, 15,   SIRT1∅, 1,   SREBP1/SREBF1↓, 2,  

Cell Death(tgid=5) ⓘ

Akt↓, 5,   Akt↑, 25,   p‑Akt↓, 4,   p‑Akt↑, 7,   APAF1↓, 1,   Apoptosis↓, 31,   BAD↓, 1,   BAX↓, 11,   BAX↑, 1,   Bax:Bcl2↓, 5,   Bcl-2↓, 1,   Bcl-2↑, 12,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 20,   Casp3↑, 1,   cl‑Casp3↓, 4,   Casp6↓, 1,   Casp9↓, 7,   Casp9↑, 1,   cl‑Casp9↓, 1,   Cyt‑c↓, 2,   Cyt‑c↑, 1,   Fas↓, 1,   Ferroptosis↓, 4,   GranB/GZMB↓, 1,   iNOS↓, 30,   iNOS↑, 1,   JNK↓, 11,   JNK↑, 1,   p‑JNK↓, 4,   MAPK↓, 13,   MAPK↑, 5,   p‑MAPK↓, 1,   necrosis↓, 1,   p38↓, 4,   p38↑, 1,   p‑p38↓, 4,   RKIP↑, 1,   TRPV1↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 1,   TRPV3↑, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach?, 1,   Ach↑, 30,   cJun↓, 1,   H3↑, 1,   H4↑, 1,   HATs↓, 1,   other?, 2,   other↓, 22,   other↑, 42,   other⇅, 1,   other↝, 45,   other∅, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 4,   eIF2α↓, 2,   p‑eIF2α↓, 1,   ER Stress↓, 11,   ER Stress↑, 1,   GRP78/BiP↓, 5,   GRP78/BiP↑, 1,   HSF1↑, 2,   HSP70/HSPA5↑, 6,   HSP90↓, 1,   HSP90↑, 2,   HSPs↝, 1,   IRE1↓, 2,   PERK↓, 3,   p‑PERK↓, 1,   UPR↑, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 3,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B↑, 1,   LC3II↓, 1,   LC3II↑, 2,   MitoP↑, 1,   p62↓, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 7,   DNArepair↑, 1,   DNMT1↓, 1,   DNMT3A↓, 1,   DNMT3A↑, 1,   p16↓, 1,   P53↓, 3,   PARP1↓, 1,   SIRT6↑, 1,   TP53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   P21↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

cFos↑, 1,   Choline↑, 3,   Diff↑, 1,   EP2↑, 1,   ERK↓, 5,   ERK↑, 9,   p‑ERK↓, 1,   p‑ERK↑, 4,   FGF↑, 1,   FOXO↑, 1,   FOXO3↑, 3,   GH↑, 1,   GSK‐3β↓, 19,   GSK‐3β↑, 3,   GSK‐3β↝, 1,   p‑GSK‐3β↓, 1,   p‑GSK‐3β↑, 3,   HDAC↓, 1,   HDAC↑, 1,   HDAC1↓, 2,   HDAC2↓, 2,   HDAC3↓, 2,   IGF-1↓, 1,   IGF-1↑, 1,   Jun↓, 1,   Mst1↓, 1,   mTOR↓, 9,   mTOR↑, 3,   p‑mTOR↓, 2,   p‑mTOR↑, 1,   Nestin↑, 1,   neuroG↑, 8,   NOTCH1↑, 2,   P70S6K↓, 1,   PI3K↓, 4,   PI3K↑, 17,   p‑PI3K↓, 2,   PTEN↓, 4,   PTEN↑, 1,   p‑PTEN↓, 1,   SOX2↑, 2,   STAT↓, 1,   STAT3↓, 2,   p‑STAT3↓, 1,   TRPM7↓, 2,   TumCG↓, 1,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 8,   AntiAg↓, 1,   AntiAg↑, 11,   AP-1↓, 5,   APP↓, 19,   cl‑APP↑, 1,   ARG1/2↑, 1,   Ca+2↓, 14,   Ca+2↑, 2,   Ca+2↝, 2,   cal2↓, 1,   Cartilage↑, 1,   CD31/PECAM-1↑, 2,   CDK5↓, 3,   CLDN1↓, 1,   Ki-67↓, 1,   Ki-67↑, 2,   LRP1↑, 3,   MMP-10↓, 1,   MMP-10↝, 1,   MMP1↓, 1,   MMP2↓, 2,   MMP2↑, 1,   MMP3↓, 2,   MMP9↓, 12,   MMPs↓, 2,   MUC1↑, 1,   N-cadherin↑, 2,   NFAT↓, 1,   PKA↑, 3,   PKCδ↓, 1,   PKCδ↑, 4,   p‑PKCδ↑, 1,   PTP1B↓, 1,   RAGE↓, 2,   ROCK1↓, 1,   serineP↓, 1,   p‑SMAD2↓, 1,   SPARC↓, 1,   p‑T-cadherin↓, 1,   TGF-β↓, 3,   TGF-β↑, 2,   TGF-β1↑, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TJ↓, 1,   TJ↑, 1,   TJ↝, 1,   TumCI↓, 1,   TumCP↓, 1,   TumMeta↓, 1,   TXNIP↓, 1,   VCAM-1↓, 8,   Vim↓, 1,   ZO-1↓, 2,   β-catenin/ZEB1↑, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 2,   ATF4↓, 3,   ATF4↑, 1,   Endoglin↑, 1,   eNOS↑, 1,   p‑eNOS↑, 2,   Hif1a↓, 1,   Hif1a↑, 1,   NO↓, 29,   NO↑, 4,   TXA2↓, 1,   VEGF↓, 1,   VEGF↑, 7,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   BBB?, 2,   BBB↓, 1,   BBB↑, 75,   BBB↝, 5,   BBB∅, 2,   GastroP↑, 3,   GLUT1↑, 2,   GLUT3↑, 2,   GLUT4↑, 5,   IBI↑, 3,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX1↓, 4,   COX2/PTGS2?, 1,   COX2/PTGS2↓, 44,   COX2/PTGS2↑, 1,   CRP↓, 8,   ICAM-1↓, 4,   IFN-γ↓, 2,   IFN-γ↑, 2,   p‑IKKα↓, 2,   IL1↓, 3,   IL10↓, 3,   IL10↑, 10,   IL12↓, 2,   IL18↓, 1,   IL1β↓, 56,   IL1β↑, 2,   IL2↓, 6,   IL22↓, 1,   IL33↓, 1,   IL4↓, 5,   IL4↑, 2,   IL6↓, 52,   IL6↑, 2,   IL8↓, 5,   Imm↑, 9,   INF-γ↓, 3,   Inflam?, 1,   Inflam↓, 207,   Inflam↑, 2,   Inflam∅, 1,   IκB↓, 1,   p‑IκB↓, 1,   LPS↓, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 5,   MCP1/CCL2↝, 1,   MIP‑1α/CCL3↓, 1,   MIP2↓, 1,   MyD88↓, 3,   NF-kB↓, 64,   NF-kB↑, 1,   p‑NF-kB↓, 4,   NK cell↑, 1,   p‑p65↓, 1,   PGE2↓, 15,   RANTES↓, 1,   TLR1↓, 1,   TLR2↓, 4,   TLR3↓, 1,   TLR4↓, 12,   TLR4↑, 1,   TNF-α↓, 85,   TRIF↓, 2,   VitD↑, 2,  

Cellular Microenvironment(tgid=17) ⓘ

NOX↓, 3,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 12,   AChE↓, 81,   AChE↝, 2,   AChE∅, 4,   ADAM10↑, 6,   BChE↓, 12,   BDNF↓, 1,   BDNF↑, 83,   BDNF∅, 2,   BrainVol↑, 2,   BrainVol↝, 1,   BrainVol∅, 3,   ChAT↑, 14,   GABA↓, 2,   GABA↑, 4,   MAOA↓, 5,   MAOA↝, 1,   monoA↑, 1,   NGF↑, 7,   PSD95?, 1,   PSD95↑, 11,   tau?, 1,   tau↓, 33,   p‑tau↓, 48,   TrkB↑, 8,   TrkB↝, 1,  

Protein Aggregation(tgid=19) ⓘ

AEP↓, 1,   AGEs↓, 3,   Aβ?, 1,   Aβ↓, 171,   Aβ↑, 2,   Aβ∅, 4,   BACE/β-secretase↓, 39,   BACE/β-secretase↑, 2,   BACE/β-secretase↝, 1,   IDE↑, 3,   MAOB↓, 3,   NEP↑, 1,   NLRP3↓, 17,   NLRP3↑, 1,   PP2A↑, 3,   β-Amyloid↓, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

cortisol↓, 1,   ER(estro)↓, 1,   ER(estro)↑, 1,   ERβ/ESR2↑, 1,   RAAS↓, 1,   testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 22,   BioAv↑, 59,   BioAv⇅, 1,   BioAv↝, 28,   BioEnh↑, 2,   ChemoSen↑, 2,   DDS↑, 1,   Dose?, 3,   Dose↓, 3,   Dose↑, 8,   Dose⇅, 1,   Dose↝, 116,   eff↓, 6,   eff↑, 96,   eff↝, 7,   eff∅, 1,   Half-Life?, 1,   Half-Life↓, 8,   Half-Life↑, 5,   Half-Life↝, 13,   P450↓, 1,   P450↑, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT?, 1,   ALAT↓, 11,   ALAT∅, 1,   ALP↓, 1,   AST↓, 12,   AST∅, 1,   BG↓, 1,   Bil↑, 1,   BloodF↑, 4,   BMD↑, 4,   BMPs↑, 1,   BP↓, 23,   BP↝, 1,   BP∅, 2,   Calcium↑, 2,   Calcium↝, 2,   creat↓, 3,   CRP↓, 8,   Ferritin↑, 1,   GutMicro↑, 25,   Hcy/homoC↓, 19,   Hcy/homoC↝, 2,   HER2/EBBR2↓, 1,   hs-CRP↓, 1,   IL6↓, 52,   IL6↑, 2,   Ki-67↓, 1,   Ki-67↑, 2,   LDH↓, 11,   LDH↑, 1,   Mag↑, 2,   NOS2↓, 1,   RAGE↓, 2,   TP53↑, 1,   Urea↓, 1,   VitD↑, 2,  

Functional Outcomes(tgid=23) ⓘ

Anger↓, 1,   AntiAge↑, 9,   antiAll↑, 1,   AntiArt↑, 3,   AntiCan↑, 10,   AntiDiabetic↑, 13,   AntiMyl↑, 1,   antiPs↑, 3,   AntiTum↑, 1,   BOLD↑, 2,   cardioP↓, 1,   cardioP↑, 48,   chemoP↑, 5,   chemoPv↑, 3,   ChemoSideEff↓, 1,   cognitive?, 3,   cognitive↓, 16,   cognitive↑, 589,   cognitive↝, 9,   cognitive?, 1,   cognitive∅, 27,   fatigue↓, 1,   hepatoP↑, 26,   memory?, 2,   memory↓, 2,   memory↑, 231,   memory∅, 4,   Mood↑, 20,   Mood↝, 1,   motorD↓, 1,   motorD↑, 30,   neuroP?, 1,   neuroP↓, 1,   neuroP↑, 259,   neuroP↝, 1,   Obesity↓, 10,   OS↑, 11,   Pain↓, 5,   QoL?, 1,   QoL↑, 4,   QoL∅, 1,   radioP↑, 3,   RenoP↑, 8,   Risk↓, 37,   Risk↑, 6,   Risk↝, 1,   Risk∅, 1,   Sleep↑, 9,   STEP↓, 1,   Strength↑, 5,   toxicity↓, 29,   toxicity↑, 2,   toxicity↝, 4,   toxicity∅, 9,   Weight↓, 3,   Weight↝, 1,   Weight∅, 1,   Wound Healing↑, 6,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 3,   AntiViral↑, 6,   Bacteria↓, 3,   Diar↓, 1,   Inf↓, 1,   IRF3↓, 3,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

CA↑, 1,   Catechins↑, 1,   FA↑, 1,   GA↑, 1,   Phen↑, 1,   QC↑, 1,  
Total Targets: 647

Scientific Paper Hit Count for: cognitive, cognitive
32 Folic Acid, Vit B9
29 Vitamin B12
24 Magnetic Fields
21 Hydrogen Gas
19 Alpha-Lipoic-Acid
15 Vitamin B6,pyridoxine
15 Curcumin
13 beta-carotene(VitA)
13 Lutein
13 Choline
13 Phosphatidylserine
12 Zeaxanthin
12 Urolithin
11 Exercise
11 Centella asiatica / Gotu kola → asiaticoside
11 Ginkgo biloba-EGb 761
11 Thymoquinone
10 Bacopa monnieri
10 Chlorogenic acid
10 Crocetin
10 Quercetin
9 Anthocyanins
9 Aromatherapy
9 Vitamin E
9 Resveratrol
9 MCToil
9 Vitamin D3
8 Berberine
8 Lycopene
8 Selenium NanoParticles
8 Huperzine A/Huperzia serrata
8 Ferulic acid
8 Ginseng
7 flavonoids
7 Ashwagandha(Withaferin A)
7 Mung Bean Sprouts
7 Silicic Acid
7 Magnetic Field Rotating
7 Rosmarinic acid
7 Salvia officinalis
6 Allicin (mainly Garlic)
6 Gamma-aminobutyric acid
6 Luteolin
6 Mushroom Lion’s Mane
6 EMF
6 Sulforaphane (mainly Broccoli)
6 Silymarin (Milk Thistle) silibinin
5 5-Hydroxytryptophan
5 Vitamin C (Ascorbic Acid)
5 Aluminum
5 Vitamin B3,Niacin
5 Caffeic acid
5 Carvacrol
5 Carnosine
5 EGCG (Epigallocatechin Gallate)
5 Ginkgo biloba
5 HydroxyTyrosol
5 Magnesium
5 Rutin
5 Taurine
5 Vitamin K2
4 Acetyl-l-carnitine
4 Docosahexaenoic Acid
4 Emodin
4 Ginkgolide B
4 isoquercitrin
4 Licochalcone A
4 Spermidine
4 Vitamin B1/Thiamine
3 Baicalein
3 Boron
3 Boswellia (frankincense)
3 Capsaicin
3 Chocolate
3 Cinnamon
3 Coenzyme Q10
3 Galantamine
3 diet Short Term Fasting
3 Flickering Light Stimulation
3 Shilajit/Fulvic Acid
3 Honokiol
3 Hormone replacement therapy
3 Oleuropein
3 Isoliquiritigenin
3 isoorientin
3 Magnolol
3 Moringa oleifera
3 nicotinamide adenine dinucleotide
3 Piperine
3 Pterostilbene
3 Radio Frequency
2 Serotonin, 5-hydroxytryptamine
2 alpha Linolenic acid
2 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
2 Apigenin (mainly Parsley)
2 Artemisinin
2 Betulinic acid
2 Carnosic acid
2 Caffeine
2 chitosan
2 Lecithin
2 Chrysin
2 Chyawanprash
2 Ellagic acid
2 Protocatechuic acid
2 Angelica archangelica / Garden Angelica
2 Fisetin
2 Bifidobacterium animalis subsp. lactis GCL2505
2 Radiotherapy/Radiation
2 isoflavones
2 Potassium
2 Kaempferol
2 Licorice
2 Lactoferrin/Talactoferrin
2 Marjoram (Origanum majorana)
2 Propolis -bee glue
2 Phenolic Acids
2 Shikonin
2 Ursolic acid
1 dietMediterranean
1 Baicalin
1 Beta-Caryophyllene
1 borneol
1 α-Bisabolol / Chamomile oil
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Cichoric acid / Chicoric acid
1 Rivastigmine
1 Date Fruit Extract
1 diet Fermented Foods
1 diet Methionine-Restricted Diet
1 Eurycomanone
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Formononetin
1 Genistein (soy isoflavone)
1 Graviola
1 hydrogen sulfide
1 Helleborus niger extracts – Christmas Rose
1 Isobavachalcone
1 Inulin Prebiotic
1 Isovitexin
1 SDG/lignans
1 Linalool
1 Methylene blue
1 Melatonin
1 Myricetin
1 Naringin
1 Olive Oil
1 Phenylbutyrate
1 Hydroxycinnamic-acid
1 Piperlongumine
1 Sinapic acid
1 S-adenosyl-L-methionine
1 Selenium
1 Metformin
1 Sesame seeds and Oil
1 Shankhpushpi
1 Chemotherapy
1 Thymol-Thymus vulgaris
1 Vitamin A, Retinoic Acid
1 probiotics
1 Vitexin
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:557  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page