Database Query Results : , , ATP

ATP, Adenosine triphosphate: Click to Expand ⟱
Source:
Type:
Adenosine triphosphate (ATP) is the source of energy for use and storage at the cellular level.
Cellular ATP levels are critical for cell survival, and several reports have shown that reductions in cellular ATP levels can lead to apoptosis and other types of cell death in cancer cells, depending on the level of depletion.
Adenosine triphosphate (ATP) is one of the main biochemical components of the tumor microenvironment (TME), where it can promote tumor progression or tumor suppression depending on its concentration and on the specific ecto-nucleotidases and receptors expressed by immune and cancer cells.

Cancer cells, unlike normal cells, derive as much as 60% of their ATP from glycolysis via the “Warburg effect”, and the remaining 40% is derived from mitochondrial oxidative phosphorylation.


Scientific Papers found: Click to Expand⟱
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑,
681- EGCG,    Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models
- vitro+vivo, BC, NA
Casp3↑, Casp8↑, Casp9↑, TumAuto↑, Beclin-1↝, ATG5↝, GlucoseCon↓, lactateProd↓, ATP↝, HK2↓, LDHA↓, Hif1a↓, GLUT1↓, TumVol↓, VEGF↓,
889- QC,    The multifaceted role of quercetin derived from its mitochondrial mechanism
- vitro+vivo, Var, NA
MMP↓, ATP↝, OXPHOS↝, ROS↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Results for Effect on Cancer/Diseased Cells:
angioG↓,1,   AntiCan↑,1,   Apoptosis↑,1,   ATG5↝,1,   ATP↝,2,   Beclin-1↝,1,   Casp3↑,1,   Casp8↑,1,   Casp9↑,1,   Cyc↓,1,   GlucoseCon↓,1,   GLUT1↓,1,   HDAC↓,1,   HIF-1↓,1,   Hif1a↓,1,   HK2↓,1,   IGF-1↓,1,   lactateProd↓,1,   LDHA↓,1,   MMP↓,1,   OXPHOS↝,1,   PSA↓,1,   Risk↓,1,   ROS↑,1,   TumAuto↑,1,   TumCMig↓,1,   TumVol↓,2,   VEGF↓,1,  
Total Targets: 28

Results for Effect on Normal Cells:
ATP↝,1,   BMD↑,1,   BMPs↑,1,   Ca+2↝,1,   Calcium↑,1,   Catalase↑,1,   chemoP↑,1,   ChemoSideEff↓,1,   cognitive↑,1,   Dose↑,1,   Dose↝,1,   eff↑,1,   GPx↑,1,   hs-CRP↓,1,   Inflam↓,1,   Mag↑,1,   memory↑,1,   NAD↝,1,   neuroP↑,1,   Risk↓,1,   SAM-e↑,1,   selectivity↑,1,   serineP↓,1,   SOD↑,1,   testos↑,1,   TNF-α↓,1,   VitD↑,1,  
Total Targets: 27

Scientific Paper Hit Count for: ATP, Adenosine triphosphate
1 Boron
1 EGCG (Epigallocatechin Gallate)
1 Quercetin
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:21  State#:0  Dir#:4
wNotes=0 sortOrder:rid,rpid

 

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