| Source: CGL-Driver Genes |
| Type: TSG |
| The RB1 gene is a critical tumor suppressor gene that plays a significant role in regulating the cell cycle, thereby preventing uncontrolled cell growth and tumor formation. The RB1 gene encodes the retinoblastoma protein (pRB), which helps control the cell cycle by regulating the transition from the G1 (gap 1) phase to the S (synthesis) phase. When functioning properly, pRB binds to and inhibits transcription factors that promote cell division. The loss of RB1 function is often associated with a more aggressive tumor phenotype and poorer clinical outcomes. |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:1 prod#:% Target#:270 State#:0 Dir#:2
wNotes=0 sortOrder:rid,rpid