Database Query Results : , , BMPs

BMPs, Bone morphogenetic protein: Click to Expand ⟱
Source:
Type:
BMPs are important cytokines belonging to the Transforming Growth Factor (TGF)-β superfamily. BMP2 is highly overexpressed in human non-small cell lung cancer (NSCLC) and correlates with tumor stage and metastatic burden. BMP-2 level from patients with bone metastasis is significantly higher compared to patients without bone metastasis.
BMPs display significantly higher expression in tumors, which have been used as new biomarkers for the prognosis of cancer patients.
However, some data revealed an opposite role of BMP signaling in tumors. BMP-10 was downregulated in gastric cancer samples. BMP-6 expression was also absent in breast cancer tissues and might suppress breast cancer metastasis.
Scientific Papers found: Click to Expand⟱
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑,
153- CUR,    Curcumin Inhibits Prostate Cancer Bone Metastasis by Up-Regulating Bone Morphogenic Protein-7 in Vivo
- in-vivo, Pca, C4-2B
PSA↓, TGF-β↓, BMPs↑,
2894- HNK,    Pharmacological features, health benefits and clinical implications of honokiol
- Review, Var, NA - Review, AD, NA
*BioAv↓, *neuroP↑, *BBB↑, *ROS↓, *Keap1↑, *NRF2↑, *Casp3↓, *SIRT3↑, *Rho↓, *ERK↓, *NF-kB↓, angioG↓, RAS↓, PI3K↓, Akt↓, mTOR↓, *memory↑, *Aβ↓, *PPARγ↑, *PGC-1α↑, NF-kB↓, Hif1a↓, VEGF↓, HO-1↓, Foxm1↓, p27↑, P21↑, CDK2↓, CDK4↓, CDK6↓, cycD1↓, Twist↓, MMP2↓, Rho↑, ROCK1↑, TumCMig↓, cFLIP↓, BMPs↑, OCR↑, ECAR↓, *AntiAg↑, *cardioP↑, *antiOx↑, *ROS↓, P-gp↓,
2868- HNK,    Honokiol: A review of its pharmacological potential and therapeutic insights
- Review, Var, NA - Review, Sepsis, NA
*P-gp↓, *ROS↓, *TNF-α↓, *IL10↓, *IL6↓, eIF2α↑, CHOP↑, GRP78/BiP↑, BAX↑, cl‑Casp9↑, p‑PERK↑, ER Stress↑, Apoptosis↑, MMPs↓, cFLIP↓, CXCR4↓, Twist↓, HDAC↓, BMPs↑, p‑STAT3↓, mTOR↓, EGFR↓, NF-kB↓, Shh↓, VEGF↓, tumCV↓, TumCMig↓, TumCI↓, ERK↓, Akt↓, Bcl-2↓, Nestin↓, CD133↓, p‑cMET↑, RAS↑, chemoP↑, *NRF2↑, *NADPH↓, *p‑Rac1↓, *ROS↓, *IKKα↑, *NF-kB↓, *COX2↓, *PGE2↓, *Casp3↓, *hepatoP↑, *antiOx↑, *GSH↑, *Catalase↑, *RenoP↑, *ALP↓, *AST↓, *ALAT↓, *neuroP↑, *cardioP↑, *HO-1↑, *Inflam↓,
498- MF,    Stimulation of osteogenic differentiation in human osteoprogenitor cells by pulsed electromagnetic fields: an in vitro study
- in-vitro, NA, NA
Calcium↑, MMP1↑, MMP3↑, BMPs↑,
4149- MF,    Pulsed Electro-Magnetic Field (PEMF) Effect on Bone Healing in Animal Models: A Review of Its Efficacy Related to Different Type of Damage
- Review, NA, NA
*other↑, *BDNF↑, *BMPs↑, *BMD↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6

Results for Effect on Cancer/Diseased Cells:
Akt↓,2,   angioG↓,2,   AntiCan↑,1,   Apoptosis↑,2,   BAX↑,1,   Bcl-2↓,1,   BMPs↑,4,   Calcium↑,1,   cl‑Casp9↑,1,   CD133↓,1,   CDK2↓,1,   CDK4↓,1,   CDK6↓,1,   cFLIP↓,2,   chemoP↑,1,   CHOP↑,1,   p‑cMET↑,1,   CXCR4↓,1,   Cyc↓,1,   cycD1↓,1,   ECAR↓,1,   EGFR↓,1,   eIF2α↑,1,   ER Stress↑,1,   ERK↓,1,   Foxm1↓,1,   GRP78/BiP↑,1,   HDAC↓,2,   HIF-1↓,1,   Hif1a↓,1,   HO-1↓,1,   IGF-1↓,1,   MMP1↑,1,   MMP2↓,1,   MMP3↑,1,   MMPs↓,1,   mTOR↓,2,   Nestin↓,1,   NF-kB↓,2,   OCR↑,1,   P-gp↓,1,   P21↑,1,   p27↑,1,   p‑PERK↑,1,   PI3K↓,1,   PSA↓,2,   RAS↓,1,   RAS↑,1,   Rho↑,1,   Risk↓,1,   ROCK1↑,1,   Shh↓,1,   p‑STAT3↓,1,   TGF-β↓,1,   TumCI↓,1,   TumCMig↓,3,   tumCV↓,1,   TumVol↓,1,   Twist↓,2,   VEGF↓,2,  
Total Targets: 60

Results for Effect on Normal Cells:
ALAT↓,1,   ALP↓,1,   AntiAg↑,1,   antiOx↑,2,   AST↓,1,   ATP↝,1,   Aβ↓,1,   BBB↑,1,   BDNF↑,1,   BioAv↓,1,   BMD↑,2,   BMPs↑,2,   Ca+2↝,1,   Calcium↑,1,   cardioP↑,2,   Casp3↓,2,   Catalase↑,2,   chemoP↑,1,   ChemoSideEff↓,1,   cognitive↑,1,   COX2↓,1,   Dose↑,1,   Dose↝,1,   eff↑,1,   ERK↓,1,   GPx↑,1,   GSH↑,1,   hepatoP↑,1,   HO-1↑,1,   hs-CRP↓,1,   IKKα↑,1,   IL10↓,1,   IL6↓,1,   Inflam↓,2,   Keap1↑,1,   Mag↑,1,   memory↑,2,   NAD↝,1,   NADPH↓,1,   neuroP↑,3,   NF-kB↓,2,   NRF2↑,2,   other↑,1,   P-gp↓,1,   PGC-1α↑,1,   PGE2↓,1,   PPARγ↑,1,   p‑Rac1↓,1,   RenoP↑,1,   Rho↓,1,   Risk↓,1,   ROS↓,4,   SAM-e↑,1,   selectivity↑,1,   serineP↓,1,   SIRT3↑,1,   SOD↑,1,   testos↑,1,   TNF-α↓,2,   VitD↑,1,  
Total Targets: 60

Scientific Paper Hit Count for: BMPs, Bone morphogenetic protein
2 Honokiol
2 Magnetic Fields
1 Boron
1 Curcumin
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:512  State#:0  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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