Database Query Results : , , TumCD

TumCD, Tumor Cell Death: Click to Expand ⟱
Source:
Type:
Tumor Cell Death
Scientific Papers found: Click to Expand⟱
2325- 2DG,    Research Progress of Warburg Effect in Hepatocellular Carcinoma
- Review, Var, NA
HK2↓, Glycolysis↓, PKM2↓, LDHA↓, TumCD↑, ChemoSen↑, eff↑,
2638- Api,    Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death
- in-vitro, lymphoma, PEL
TumCD↑, TumAuto↑, ROS↓, P53↑, Catalase↑, STAT3↓,
2635- Api,  CUR,    Synergistic Effect of Apigenin and Curcumin on Apoptosis, Paraptosis and Autophagy-related Cell Death in HeLa Cells
- in-vitro, Cerv, HeLa
TumCD↑, eff↑, TumAuto↑, ER Stress↑, Paraptosis↑, GRP78/BiP↓, Dose↝,
2003- Ash,    Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells
- in-vitro, Pca, PC3 - in-vitro, Pca, DU145 - in-vitro, Nor, TIG-1 - in-vitro, PC, LNCaP
TumCD↑, selectivity↑, cFos↑, ROS↑, *ROS∅, HSP70/HSPA5↑, Apoptosis↑, ER Stress↑, TumCCA↑,
3160- Ash,    Withaferin A: A Pleiotropic Anticancer Agent from the Indian Medicinal Plant Withania somnifera (L.) Dunal
- Review, Var, NA
TumCCA↑, H3↑, P21↑, cycA1↓, CycB↓, cycE↓, CDC2↓, CHK1↓, Chk2↓, p38↑, MAPK↑, E6↓, E7↓, P53↑, Akt↓, FOXO3↑, ROS↑, γH2AX↑, MMP↓, mitResp↓, eff↑, TumCD↑, Mcl-1↓, ER Stress↑, ATF4↑, ATF3↑, CHOP↑, NOTCH↓, NF-kB↓, Bcl-2↓, STAT3↓, CDK1↓, β-catenin/ZEB1↓, N-cadherin↓, EMT↓, Cyt‑c↑, eff↑, CDK4↓, p‑RB1↓, PARP↑, cl‑Casp3↑, cl‑Casp9↑, NRF2↑, ER-α36↓, LDHA↓, lipid-P↑, AP-1↓, COX2↓, RenoP↑, PDGFR-BB↓, SIRT3↑, MMP2↓, MMP9↓, NADPH↑, NQO1↑, GSR↑, HO-1↑, *SOD2↑, *Prx↑, *Casp3?, eff↑, Snail↓, Slug↓, Vim↓, CSCs↓, HEY1↓, MMPs↓, VEGF↓, uPA↓, *toxicity↓, CDK2↓, CDK4↓, HSP90↓,
1523- Ba,    Baicalein induces human osteosarcoma cell line MG-63 apoptosis via ROS-induced BNIP3 expression
- in-vitro, OS, MG63 - in-vitro, Nor, hFOB1.19
TumCD↑, Apoptosis↑, ROS↑, eff↓, Casp3↑, Bcl-2↓, selectivity↑, Cyt‑c↑, LDH?, BNIP3?, BAX↑,
2023- BBR,    Berberine Induces Caspase-Independent Cell Death in Colon Tumor Cells through Activation of Apoptosis-Inducing Factor
- in-vitro, Colon, NA - in-vitro, Nor, YAMC
TumCD↑, *toxicity↓, selectivity↑, ROS↑, *ROS∅, MMP↓, *MMP∅, PARP↑, BioAv↝,
2680- BBR,  PDT,    Photodynamic therapy-triggered nuclear translocation of berberine from mitochondria leads to liver cancer cell death
- in-vitro, Liver, HUH7
TumCD↑, ROS↑, TumCCA↑, ER Stress↑,
2716- BetA,    Cellular and molecular mechanisms underlying the potential of betulinic acid in cancer prevention and treatment
- Review, Var, NA
AntiCan↑, TumCD↑, TumCCA↑, ROS↑, NF-kB↓, Bcl-2↓, Half-Life↝, GLUT1↓, VEGF↓, PDK1↓,
2719- BetA,    Betulinic Acid Restricts Human Bladder Cancer Cell Proliferation In Vitro by Inducing Caspase-Dependent Cell Death and Cell Cycle Arrest, and Decreasing Metastatic Potential
- in-vitro, CRC, T24 - in-vitro, Bladder, UMUC3 - in-vitro, Bladder, 5637
TumCD↑, Apoptosis↑, TumCCA↑, CycB↓, cycA1↓, CDK2↓, CDC25↓, mtDam↑, BAX↑, cl‑PARP↑, Casp3↑, Casp8↑, Casp9↑, Snail↓, Slug↓, MMP9↓, selectivity↑, MMP↓, ROS∅, TumCMig↓, TumCI↓,
745- Bor,    Investigation of cytotoxic antiproliferative and antiapoptotic effects of nanosized boron phosphate filled sodium alginate composite on glioblastoma cancer cells
- in-vitro, GBM, U87MG - in-vitro, Nor, L929 - in-vitro, GBM, T98G
TumCD↑, *toxicity↓,
1640- CA,  MET,    Caffeic Acid Targets AMPK Signaling and Regulates Tricarboxylic Acid Cycle Anaplerosis while Metformin Downregulates HIF-1α-Induced Glycolytic Enzymes in Human Cervical Squamous Cell Carcinoma Lines
- in-vitro, Cerv, SiHa
GLS↓, NADPH↓, ROS↑, TumCD↑, AMPK↑, Hif1a↓, GLUT1↓, GLUT3↓, HK2↓, PFK↓, PKM2↓, LDH↓, cMyc↓, BAX↓, cycD1↓, PDH↓, ROS↑, Apoptosis↑, eff↑, ACLY↓, FASN↓, Bcl-2↓, Glycolysis↓,
2791- CHr,    Chrysin attenuates progression of ovarian cancer cells by regulating signaling cascades and mitochondrial dysfunction
- in-vitro, Ovarian, OV90
TumCP↓, TumCD↑, ROS↑, Ca+2↑, MMP↓, MAPK↑, PI3K↑, p‑Akt↑, PCNA↓, p‑p70S6↑, p‑ERK↑, p38↑, JNK↑, DNAdam↑, TumCCA↑, chemoP↑,
1596- Cu,  CDT,    Unveiling the promising anticancer effect of copper-based compounds: a comprehensive review
- Review, NA, NA
TumCD↑, Apoptosis↓, ROS↑, angioG↑, Cupro↑, Paraptosis↑, eff↑, eff↓, selectivity↑, DNAdam↑, eff↑, eff↑, eff↑, eff↑, Fenton↑, H2O2↑, eff↑, eff↑, eff↑, RadioS↑, ChemoSen↑, eff↑, *toxicity↝, other↑, eff↑,
474- CUR,    Modification of radiosensitivity by Curcumin in human pancreatic cancer cell lines
- in-vitro, PC, PANC1 - in-vitro, PC, MIA PaCa-2
TumCD↑, Apoptosis↑, DNAdam↑, γH2AX↑, TumCCA↑,
4456- DFE,    Induction of apoptosis and cell cycle arrest by ethyl acetate fraction of Phoenix dactylifera L. (Ajwa dates) in prostate cancer cells
- in-vitro, Pca, PC3
TumCD↑, MMP↓, mt-ROS↑, Apoptosis↑, TumCCA↑,
1847- dietFMD,  VitC,    Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers
- in-vitro, PC, PANC1
TumCG↓, ChemoSen↑, eff↑, HO-1↓, Ferritin↓, Iron↑, ROS↑, TumCD↑, IGF-1↓, eff↓, eff↓,
1863- dietFMD,  Chemo,    Effect of fasting on cancer: A narrative review of scientific evidence
- Review, Var, NA
eff↑, ChemoSideEff↓, ChemoSen↑, Insulin↓, HDAC↓, IGF-1↓, STAT5↓, BG↓, MAPK↓, HO-1↓, ATG3↑, Beclin-1↑, p62↑, SIRT1↑, LAMP2↑, OXPHOS↑, ROS↑, P53↑, DNAdam↑, TumCD↑, ATP↑, Treg lymp↓, M2 MC↓, CD8+↑, Glycolysis↓, GutMicro↑, GutMicro↑, Warburg↓, Dose↝,
2497- Fenb,    In vitro anti-tubulin effects of mebendazole and fenbendazole on canine glioma cells
- in-vitro, GBM, NA
Dose?, selectivity↑, TumCD↑, α-tubulin↓,
2849- FIS,    Activation of reactive oxygen species/AMP activated protein kinase signaling mediates fisetin-induced apoptosis in multiple myeloma U266 cells
- in-vitro, Melanoma, U266
TumCD↑, TumCCA↑, Casp3↑, Bcl-2↓, Mcl-1↓, BAX↑, BIM↑, BAD↑, AMPK↑, ACC↑, p‑Akt↓, p‑mTOR↓, ROS↑, eff↓,
2518- H2,    Hydrogen Therapy Reverses Cancer-Associated Fibroblasts Phenotypes and Remodels Stromal Microenvironment to Stimulate Systematic Anti-Tumor Immunity
- in-vitro, BC, 4T1 - in-vitro, Nor, 3T3
TumCD↑, CD4+↑, ROS↓,
2073- HNK,    Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo
- in-vitro, OS, U2OS - in-vivo, NA, NA
TumCD↑, TumAuto↑, Apoptosis↑, TumCCA↑, GRP78/BiP↑, ROS↑, eff↓, p‑ERK↑, selectivity↑, Ca+2↑, MMP↓, Casp3↑, Casp9↑, cl‑PARP↑, Bcl-2↓, Bcl-xL↓, survivin↓, LC3B-II↑, ATG5↑, TumVol↓, TumW↓, ER Stress↑,
869- Lae,    Recent updates and future perspectives about amygdalin as a potential anticancer agent: A review
TumCD↑,
2923- LT,    Luteolin induces apoptosis through endoplasmic reticulum stress and mitochondrial dysfunction in Neuro-2a mouse neuroblastoma cells
- in-vitro, NA, NA
Apoptosis↑, TumCD↑, Casp12↑, Casp9↑, Casp3↑, ER Stress↑, CHOP↑, GRP78/BiP↑, GRP94↑, cl‑ATF6↑, p‑eIF2α↑, MMP↓, JNK↓, p38↑, ERK↑, Cyt‑c↑,
2546- M-Blu,  SDT,    The sonodynamic antitumor effect of methylene blue on sarcoma180 cells in vitro
- in-vitro, sarcoma, S180
TumCD↑,
1785- MEL,    Antitumoral melatonin-loaded nanostructured lipid carriers
- in-vitro, Var, NA
selectivity↑, TumCD↑,
995- MEL,    Melatonin Treatment Triggers Metabolic and Intracellular pH Imbalance in Glioblastoma
- vitro+vivo, GBM, NA
LDHA↓, MCT4↓, lactateProd↓, i-pH↓, ROS↑, ATP↓, TumCD↑, TumCCA↑, PDH↓, Glycolysis↓, GlucoseCon↓, TumCG↓,
2235- MF,    Increase of intracellular Ca2+ concentration in Listeria monocytogenes under pulsed magnetic field
- in-vitro, Inf, NA
Ca+2↑, TumCD↑,
523- MF,  MTX,    Extremely low-frequency magnetic fields significantly enhance the cytotoxicity of methotrexate and can reduce migration of cancer cell lines via transiently induced plasma membrane damage
- in-vitro, AML, THP1 - in-vitro, NA, PC12 - in-vivo, Cerv, HeLa
H2O2↑, TumCD↑, CellMemb↑, eff↑,
533- MF,    Effects of extremely low-frequency magnetic fields on human MDA-MB-231 breast cancer cells: proteomic characterization
- in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
TumCD↑, necrosis↑, mt-ROS↑, other↑, *STAT3↓, STAT3↑,
3492- MFrot,  Chemo,  MF,    Synergistic Effect of Chemotherapy and Magnetomechanical Actuation of Fe-Cr-Nb-B Magnetic Particles on Cancer Cells
eff↑, TumCD↑,
3493- MFrot,  MF,    Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes
- in-vivo, GBM, NA
TumCD↑, MMP↓, Cyt‑c↑, Apoptosis↑, OS↑, DNAdam↑,
3494- MFrot,  MF,    Magnetically switchable mechano-chemotherapy for enhancing the death of tumour cells by overcoming drug-resistance
- in-vitro, Var, NA
eff↑, TumCD↑,
184- MFrot,  MF,    Rotating Magnetic Fields Inhibit Mitochondrial Respiration, Promote Oxidative Stress and Produce Loss of Mitochondrial Integrity in Cancer Cells
- in-vitro, GBM, GBM
ROS↑, mitResp↓, mtDam↑, Dose↝, MMP?, OCR↓, mt-H2O2↑, eff↓, SDH↓, Thiols↓, GSH↓, TumCD↑, Casp3↑, Casp7↑, MPT↑, Cyt‑c↑, selectivity↑, GSH/GSSG↓,
186- MFrot,  MF,    Selective induction of rapid cytotoxic effect in glioblastoma cells by oscillating magnetic fields
- in-vitro, GBM, GBM - in-vitro, Lung, NA
mt-ROS↑, Casp3↑, selectivity↑, TumCD↑,
595- MFrot,  VitC,  MF,    The Effect of Alternating Magnetic Field Exposure and Vitamin C on Cancer Cells
- in-vitro, PC, MIA PaCa-2 - in-vitro, CRC, SW-620 - in-vitro, NA, HT1080 - in-vitro, Pca, PC3 - in-vitro, OS, U2OS - in-vitro, BC, MCF-7 - in-vitro, Nor, CCD-18Co
TumCD↑, eff↑, *TumCG∅,
2258- MFrot,  MF,    EXTH-68. ONCOMAGNETIC TREATMENT SELECTIVELY KILLS GLIOMA CANCER CELLS BY INDUCING OXIDATIVE STRESS AND DNA DAMAGE
- in-vitro, GBM, GBM - in-vitro, Nor, SVGp12
TumVol↓, OS↑, γH2AX↑, DNAdam↑, selectivity↑, ROS↑, TumCD↑, eff↑, eff↓,
2039- PB,    TXNIP mediates the differential responses of A549 cells to sodium butyrate and sodium 4‐phenylbutyrate treatment
- in-vitro, Lung, A549 - in-vitro, Nor, HEK293
TXNIP↑, Casp3↑, Casp7↑, mt-ROS↑, GlucoseCon↓, TumCP↓, TumCD↑, IGF-2↑, HDAC↓, ROS⇅,
2078- PB,    Butyrate-induced apoptosis in HCT116 colorectal cancer cells includes induction of a cell stress response
- in-vitro, CRC, HCT116
p38↑, ER Stress↑, Casp3↑, Casp7↑, TumCD↑, Apoptosis↑, TumCP↑, HSP27↓,
1765- PG,    Enhanced cell death effects of MAP kinase inhibitors in propyl gallate-treated lung cancer cells are related to increased ROS levels and GSH depletion
- in-vitro, Lung, A549 - in-vitro, Lung, Calu-6
TumCD↑, MMP↓, ROS↑, GSH↓, Dose∅, eff↑,
2943- PL,    Piperlongumine Inhibits Thioredoxin Reductase 1 by Targeting Selenocysteine Residues and Sensitizes Cancer Cells to Erastin
- in-vitro, CRC, HCT116 - in-vitro, Lung, A549 - in-vitro, BC, MCF-7
TrxR1?, TumCD↑, ROS↑, GSH↓, eff↑,
3381- QC,    Quercetin induces cell death in cervical cancer by reducing O-GlcNAcylation of adenosine monophosphate-activated protein kinase
- in-vitro, Cerv, HeLa
SREBP1↓, TumCP↓, TumCD↑, AMPK↑, SREBP1↓, FASN↓, ACC↓,
3378- QC,    CK2 and PI3K are direct molecular targets of quercetin in chronic lymphocytic leukaemia
- in-vitro, AML, NA
CK2↓, PI3K↓, TumCD↑, Akt↓, Mcl-1↓, PTEN↑,
884- RES,  PTS,    Resveratrol and Pterostilbene Exhibit Anticancer Properties Involving the Downregulation of HPV Oncoprotein E6 in Cervical Cancer Cells
- in-vitro, Cerv, HeLa
TumCD↑, TumCCA↑, E6↓, Casp3↑, P53↑,
323- Sal,  SNP,    Combination of salinomycin and silver nanoparticles enhances apoptosis and autophagy in human ovarian cancer cells: an effective anticancer therapy
- in-vitro, BC, MDA-MB-231 - in-vitro, Ovarian, A2780S
TumCD↑, LDH↓, MDA↑, SOD↓, ROS↑, GSH↓, Catalase↓, MMP↓, P53↑, P21↑, BAX↑, Bcl-2↓, Casp3↑, Casp9↑, Apoptosis↑, TumAuto↑,
1732- SFN,    Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells
- in-vitro, BC, MCF-7 - in-vitro, BC, SUM159 - in-vivo, NA, NA
TumCD↑, CSCs↓, Wnt↓, β-catenin/ZEB1↓, *BioAv↑, angioG↓, VEGF↓, Hif1a↓, MMP2↓, MMP9↓, Casp3↑, *Half-Life∅,
3323- SIL,    Anticancer therapeutic potential of silibinin: current trends, scope and relevance
- Review, Var, NA
Inflam↓, angioG↓, antiOx↑, TumMeta↓, TumCP↓, TumCCA↑, TumCD↑, α-SMA↓, p‑Akt↓, p‑STAT3↓, COX2↓, IL6↓, MMP2↓, HIF-1↓, Snail↓, Slug↓, Zeb1↓, NF-kB↓, p‑EGFR↓, JAK2↓, PI3K↓, PD-L1↓, VEGF↓, CDK4↓, CDK2↓, cycD1↓, E2Fs↓,
2227- SK,    Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species
- in-vitro, GC, BGC-823 - in-vitro, GC, SGC-7901 - in-vitro, Nor, GES-1
selectivity↑, TumCP↓, TumCD↑, ROS↑, MMP↓, Casp↑, Cyt‑c↑, Endon↑, AIF↑, eff↓, ChemoSen↑, TumCCA↑, GSH/GSSG↓, lipid-P↑,
338- SNP,    Biogenic silver nanoparticles: In vitro and in vivo antitumor activity in bladder cancer
- vitro+vivo, Bladder, 5637
TumCD↑, Apoptosis↑, TumCMig↓, TumCP↓,
339- SNP,    Cancer cell specific cytotoxic potential of the silver nanoparticles synthesized using the endophytic fungus, Penicillium citrinum CGJ-C2
- in-vitro, BC, MCF-7 - in-vitro, Melanoma, A431 - in-vitro, HCC, HepG2
TumCD↑,
340- SNP,    Screening bioactivities of Caesalpinia pulcherrima L. swartz and cytotoxicity of extract synthesized silver nanoparticles on HCT116 cell line
- in-vitro, CRC, HCT116
TumCD↑,
341- SNP,    Bioprospecting a native silver-resistant Bacillus safensis strain for green synthesis and subsequent antibacterial and anticancer activities of silver nanoparticles
- in-vitro, Liver, HepG2
TumCD↑, ROS↑,
352- SNP,    Synthesis of silver nanoparticles (Ag NPs) for anticancer activities (MCF 7 breast and A549 lung cell lines) of the crude extract of Syzygium aromaticum
- in-vitro, BC, MCF-7
TumCD↑,
354- SNP,    Silver nanoparticles induce SH-SY5Y cell apoptosis via endoplasmic reticulum- and mitochondrial pathways that lengthen endoplasmic reticulum-mitochondria contact sites and alter inositol-3-phosphate receptor function
- in-vitro, neuroblastoma, SH-SY5Y
TumCD↑, ER Stress↑, GRP78/BiP↑, p‑PERK↑, CHOP↑, Ca+2↑, XBP-1↑, p‑IRE1↑,
364- SNP,    Differential Action of Silver Nanoparticles on ABCB1 (MDR1) and ABCC1 (MRP1) Activity in Mammalian Cell Lines
- in-vitro, Lung, A549 - in-vitro, Hepat, HepG2 - in-vitro, CRC, SW-620
TumCD↑,
365- SNP,    Silver nanoparticles affect glucose metabolism in hepatoma cells through production of reactive oxygen species
- in-vitro, Hepat, HepG2
ROS↑, GlucoseCon↓, TumCD↑, NRF2↓,
4379- SNP,    Exposure to silver nanoparticles induces size- and dose-dependent oxidative stress and cytotoxicity in human colon carcinoma cells
- in-vitro, CRC, LoVo
eff↑, TumCD↑, ROS↑, Bacteria↓,
4374- SNP,    Enhancing antitumor activity of silver nanoparticles by modification with cell-penetrating peptides
- in-vitro, BC, MCF-7
eff↑, TumCD↑,
4373- SNP,    In vitro toxicity of silver nanoparticles at noncytotoxic doses to HepG2 human hepatoma cells
- in-vitro, Liver, HepG2
TumCD↑,
4372- SNP,    Negligible particle-specific toxicity mechanism of silver nanoparticles: the role of Ag+ ion release in the cytosol
- in-vitro, Cerv, HeLa - in-vitro, Lung, A549
TumCD↑,
4402- SNP,    Enhancement of Triple-Negative Breast Cancer-Specific Induction of Cell Death by Silver Nanoparticles by Combined Treatment with Proteotoxic Stress Response Inhibitors
- in-vitro, BC, BT549 - in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
TumCD↑, selectivity↑, *toxicity↝, Dose↝, OS↑,
4406- SNP,    Silver nanoparticles achieve cytotoxicity against breast cancer by regulating long-chain noncoding RNA XLOC_006390-mediated pathway
- in-vitro, BC, MCF-7 - in-vitro, BC, T47D - in-vitro, BC, MDA-MB-231
TumCD↑, other↓, P53↑, TumCCA↑, Apoptosis↑, ChemoSen↑, tumCV↓, γH2AX↑, SOX4↓,
4364- SNP,    Selective cytotoxicity of green synthesized silver nanoparticles against the MCF-7 tumor cell line and their enhanced antioxidant and antimicrobial properties
- in-vitro, BC, MCF-7
TumCD↑, selectivity↑, *antiOx↑, *Inflam↓, AntiTum↑, ROS↑,
4361- SNP,  GoldNP,    Biocompatible silver, gold and silver/gold alloy nanoparticles for enhanced cancer therapy: in vitro and in vivo perspectives
- in-vivo, Liver, HepG2
TumCD↑, TumVol↓, *toxicity↝, hepatoP↑,
4358- SNP,  HPT,  Rad,    Silver nanocrystals mediated combination therapy of radiation with magnetic hyperthermia on glioma cells
- in-vitro, GBM, U251
RadioS↑, eff↑, TumCD↑,
4430- SNP,    Evaluation of the Genotoxic and Oxidative Damage Potential of Silver Nanoparticles in Human NCM460 and HCT116 Cells
- in-vitro, Colon, HCT116 - in-vitro, Nor, NCM460
*Bacteria↓, ROS↑, p‑p38↑, BAX↑, Bcl-2↓, BAX↑, P21↑, TumCD↑, toxicity↝,
4439- SNP,    Anticancer Potential of Green Synthesized Silver Nanoparticles Using Extract of Nepeta deflersiana against Human Cervical Cancer Cells (HeLA)
- in-vitro, Cerv, HeLa
ROS↑, lipid-P↑, MMP↓, GSH↓, TumCCA↑, Apoptosis↑, Necroptosis↑, TumCD↑, Dose↝,
2093- TQ,    Regulation of NF-κB Expression by Thymoquinone; A Role in Regulating Pro-Inflammatory Cytokines and Programmed Cell Death in Hepatic Cancer Cells
- in-vitro, Liver, HepG2 - in-vitro, Nor, NA
TumCD↑, selectivity↑, Casp3↑, DLC1↑, NF-kB↑, LDH↑, *toxicity↓,
4468- VitC,  Se,    Selenium modulates cancer cell response to pharmacologic ascorbate
- in-vivo, GBM, U87MG - in-vitro, CRC, HCT116
eff↓, TumCD↑, ChemoSen↑, ROS⇅, DNAdam↑, PARP↑, NAD↓, Glycolysis↓, Fenton↑, lipid-P↑, eff↓, H2O2↑, other↝,
1819- VitC,  VitK3,    The association of vitamins C and K3 kills cancer cells mainly by autoschizis, a novel form of cell death. Basis for their potential use as coadjuvants in anticancer therapy
- Review, Var, NA
Dose?, TumCD↑, selectivity↑, H2O2↑, ROS↑, DNAdam↑,
3136- VitC,    Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer
- in-vitro, Colon, SW48 - in-vitro, Colon, LoVo
ERK↓, p‑PKM2↓, GLUT1↓, Warburg↓, TumCD↑, eff↑, ROS↓, cMyc↓,
628- VitC,  Mg,    Enhanced Anticancer Effect of Adding Magnesium to Vitamin C Therapy: Inhibition of Hormetic Response by SVCT-2 Activation
- in-vivo, Colon, CT26 - in-vitro, NA, MCF-7 - in-vitro, NA, SkBr3
AntiCan↑, SVCT-2↝, TumCD↑, ROS↑, P21↑, proCasp3↑, TumVol↓, DNAdam↑, NAD↓,
600- VitC,  VitK3,    Serum markers variation consistent with autoschizis induced by ascorbic acid-menadione in patients with prostate cancer
- in-vitro, NA, NA
autoS↑, TumCD↑,
611- VitC,    Characterization of a new malignant human T-cell line (PFI-285) sensitive to ascorbic acid
- in-vitro, NA, NA
TumCD↑,
1835- VitK3,  VitC,    Potential therapeutic application of the association of vitamins C and K3 in cancer treatment
- Review, Var, NA
ROS↑, TumCD↑, TumCG↓, OS↑,
1760- WBV,    Molecular jackhammers eradicate cancer cells by vibronic-driven action
- in-vitro, Melanoma, NA
TumCD↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 76

Results for Effect on Cancer/Diseased Cells:
ACC↓,1,   ACC↑,1,   ACLY↓,1,   AIF↑,1,   Akt↓,2,   p‑Akt↓,2,   p‑Akt↑,1,   AMPK↑,3,   angioG↓,2,   angioG↑,1,   AntiCan↑,2,   antiOx↑,1,   AntiTum↑,1,   AP-1↓,1,   Apoptosis↓,1,   Apoptosis↑,14,   ATF3↑,1,   ATF4↑,1,   cl‑ATF6↑,1,   ATG3↑,1,   ATG5↑,1,   ATP↓,1,   ATP↑,1,   autoS↑,1,   Bacteria↓,1,   BAD↑,1,   BAX↓,1,   BAX↑,6,   Bcl-2↓,8,   Bcl-xL↓,1,   Beclin-1↑,1,   BG↓,1,   BIM↑,1,   BioAv↝,1,   BNIP3?,1,   Ca+2↑,4,   Casp↑,1,   Casp12↑,1,   Casp3↑,13,   cl‑Casp3↑,1,   proCasp3↑,1,   Casp7↑,3,   Casp8↑,1,   Casp9↑,4,   cl‑Casp9↑,1,   Catalase↓,1,   Catalase↑,1,   CD4+↑,1,   CD8+↑,1,   CDC2↓,1,   CDC25↓,1,   CDK1↓,1,   CDK2↓,3,   CDK4↓,3,   CellMemb↑,1,   cFos↑,1,   chemoP↑,1,   ChemoSen↑,7,   ChemoSideEff↓,1,   CHK1↓,1,   Chk2↓,1,   CHOP↑,3,   CK2↓,1,   cMyc↓,2,   COX2↓,2,   CSCs↓,2,   Cupro↑,1,   cycA1↓,2,   CycB↓,2,   cycD1↓,2,   cycE↓,1,   Cyt‑c↑,6,   DLC1↑,1,   DNAdam↑,9,   Dose?,2,   Dose↝,5,   Dose∅,1,   E2Fs↓,1,   E6↓,2,   E7↓,1,   eff↓,11,   eff↑,29,   p‑EGFR↓,1,   p‑eIF2α↑,1,   EMT↓,1,   Endon↑,1,   ER Stress↑,8,   ER-α36↓,1,   ERK↓,1,   ERK↑,1,   p‑ERK↑,2,   FASN↓,2,   Fenton↑,2,   Ferritin↓,1,   FOXO3↑,1,   GLS↓,1,   GlucoseCon↓,3,   GLUT1↓,3,   GLUT3↓,1,   Glycolysis↓,5,   GRP78/BiP↓,1,   GRP78/BiP↑,3,   GRP94↑,1,   GSH↓,5,   GSH/GSSG↓,2,   GSR↑,1,   GutMicro↑,2,   H2O2↑,4,   mt-H2O2↑,1,   H3↑,1,   Half-Life↝,1,   HDAC↓,2,   hepatoP↑,1,   HEY1↓,1,   HIF-1↓,1,   Hif1a↓,2,   HK2↓,2,   HO-1↓,2,   HO-1↑,1,   HSP27↓,1,   HSP70/HSPA5↑,1,   HSP90↓,1,   IGF-1↓,2,   IGF-2↑,1,   IL6↓,1,   Inflam↓,1,   Insulin↓,1,   p‑IRE1↑,1,   Iron↑,1,   JAK2↓,1,   JNK↓,1,   JNK↑,1,   lactateProd↓,1,   LAMP2↑,1,   LC3B-II↑,1,   LDH?,1,   LDH↓,2,   LDH↑,1,   LDHA↓,3,   lipid-P↑,4,   M2 MC↓,1,   MAPK↓,1,   MAPK↑,2,   Mcl-1↓,3,   MCT4↓,1,   MDA↑,1,   mitResp↓,2,   MMP?,1,   MMP↓,12,   MMP2↓,3,   MMP9↓,3,   MMPs↓,1,   MPT↑,1,   mtDam↑,2,   p‑mTOR↓,1,   N-cadherin↓,1,   NAD↓,2,   NADPH↓,1,   NADPH↑,1,   Necroptosis↑,1,   necrosis↑,1,   NF-kB↓,3,   NF-kB↑,1,   NOTCH↓,1,   NQO1↑,1,   NRF2↓,1,   NRF2↑,1,   OCR↓,1,   OS↑,4,   other↓,1,   other↑,2,   other↝,1,   OXPHOS↑,1,   P21↑,4,   p38↑,4,   p‑p38↑,1,   P53↑,6,   p62↑,1,   p‑p70S6↑,1,   Paraptosis↑,2,   PARP↑,3,   cl‑PARP↑,2,   PCNA↓,1,   PD-L1↓,1,   PDGFR-BB↓,1,   PDH↓,2,   PDK1↓,1,   p‑PERK↑,1,   PFK↓,1,   i-pH↓,1,   PI3K↓,2,   PI3K↑,1,   PKM2↓,2,   p‑PKM2↓,1,   PTEN↑,1,   RadioS↑,2,   p‑RB1↓,1,   RenoP↑,1,   ROS↓,3,   ROS↑,30,   ROS⇅,2,   ROS∅,1,   mt-ROS↑,4,   SDH↓,1,   selectivity↑,16,   SIRT1↑,1,   SIRT3↑,1,   Slug↓,3,   Snail↓,3,   SOD↓,1,   SOX4↓,1,   SREBP1↓,2,   STAT3↓,2,   STAT3↑,1,   p‑STAT3↓,1,   STAT5↓,1,   survivin↓,1,   SVCT-2↝,1,   Thiols↓,1,   toxicity↝,1,   Treg lymp↓,1,   TrxR1?,1,   TumAuto↑,4,   TumCCA↑,16,   TumCD↑,76,   TumCG↓,3,   TumCI↓,1,   TumCMig↓,2,   TumCP↓,6,   TumCP↑,1,   tumCV↓,1,   TumMeta↓,1,   TumVol↓,4,   TumW↓,1,   TXNIP↑,1,   uPA↓,1,   VEGF↓,4,   Vim↓,1,   Warburg↓,2,   Wnt↓,1,   XBP-1↑,1,   Zeb1↓,1,   α-SMA↓,1,   α-tubulin↓,1,   β-catenin/ZEB1↓,2,   γH2AX↑,4,  
Total Targets: 246

Results for Effect on Normal Cells:
antiOx↑,1,   Bacteria↓,1,   BioAv↑,1,   Casp3?,1,   Half-Life∅,1,   Inflam↓,1,   MMP∅,1,   Prx↑,1,   ROS∅,2,   SOD2↑,1,   STAT3↓,1,   toxicity↓,4,   toxicity↝,3,   TumCG∅,1,  
Total Targets: 14

Scientific Paper Hit Count for: TumCD, Tumor Cell Death
20 Silver-NanoParticles
10 Magnetic Fields
9 Vitamin C (Ascorbic Acid)
7 Magnetic Field Rotating
3 VitK3,menadione
2 Apigenin (mainly Parsley)
2 Curcumin
2 Ashwagandha
2 Berberine
2 Betulinic acid
2 diet FMD Fasting Mimicking Diet
2 Chemotherapy
2 Melatonin
2 Phenylbutyrate
2 Quercetin
1 2-DeoxyGlucose
1 Baicalein
1 Photodynamic Therapy
1 Boron
1 Caffeic acid
1 Metformin
1 Chrysin
1 Copper and Cu NanoParticlex
1 chemodynamic therapy
1 Date Fruit Extract
1 Fenbendazole
1 Fisetin
1 Hydrogen Gas
1 Honokiol
1 Laetrile B17 Amygdalin
1 Luteolin
1 Methylene blue
1 SonoDynamic Therapy UltraSound
1 methotrexate
1 Propyl gallate
1 Piperlongumine
1 Resveratrol
1 Pterostilbene
1 salinomycin
1 Sulforaphane (mainly Broccoli)
1 Silymarin (Milk Thistle) silibinin
1 Shikonin
1 Gold NanoParticles
1 Hyperthermia
1 Radiotherapy/Radiation
1 Thymoquinone
1 Selenium
1 Magnesium
1 Whole Body Vibration
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:619  State#:0  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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