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3941- 5HT,  dietMed,  VitB12,  FA,  VitC  Nutrition strategies that improve cognitive function
- Review, AD, NA
*other↑, *other↓, *cognitive↑, *eff↑, *eff↑,
3972- ACNs,    Recent Research on the Health Benefits of Blueberries and Their Anthocyanins
- Review, AD, NA - Review, Park, NA
*cardioP↑, *neuroP↑, *Inflam↓, *antiOx↓, *GutMicro↑, *Half-Life↑, *LDL↓, *adiP↓, *HDL↑, *CRP↓, *IL1β↓, *Risk↓, *Risk↓, *cognitive↑, *memory↑, *other↑, *BOLD↑, *NO↓, *MDA↓, *GSH↑, *VitC↑, *SOD↑, *GPx↑, *eff↓, *eff↓, *eff↓, *eff↝, *Risk↓,
2463- AL,    Garlic as an antithrombotic and antiplatelet aggregation agent
- Review, Nor, NA
AntiAg↑, other↑,
2660- AL,    Allicin: A review of its important pharmacological activities
- Review, AD, NA - Review, Var, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2↓, p‑FAK↓,
2666- AL,    Targeting the Interplay of Autophagy and ROS for Cancer Therapy: An Updated Overview on Phytochemicals
- Review, Var, NA
Inflam↓, AntiCan↑, ROS↑, MAPK↑, JNK↑, TumAuto↑, other↑, Dose↝, MALAT1↓, Wnt↓, β-catenin/ZEB1↓,
3548- ALA,    How Alpha Linolenic Acid May Sustain Blood–Brain Barrier Integrity and Boost Brain Resilience against Alzheimer’s Disease
- Review, AD, NA
*BBB↑, *other↑, *other↑,
4135- Alum,    Aluminum Should Now Be Considered a Primary Etiological Factor in Alzheimer's Disease
- Review, AD, NA
*Risk↑, *cognitive↓, *neuroP↓, *other↑, *other↝,
3822- Aroma,    Aromatherapy in the treatment of Alzheimer's disease: A systematic review
- Review, AD, NA
*cognitive↑, *other↑, *other↓, *BioAv↑, *BBB?,
1473- BCA,  SFN,    An Insight on Synergistic Anti-cancer Efficacy of Biochanin A and Sulforaphane Combination Against Breast Cancer
- in-vitro, BC, MCF-7
eff↑, ROS↑, other↑, ERK↓, Apoptosis↑,
3694- BM,    Use of Bacopa monnieri in the Treatment of Dementia Due to Alzheimer Disease: Systematic Review of Randomized Controlled Trials
- Review, AD, NA
*cognitive∅, *other↑,
3504- Bor,    Boron Contents of German Mineral and Medicinal Waters and Their Bioavailability in Drosophila melanogaster and Humans
- Review, NA, NA
other↑, BioAv↑,
3503- Bor,    Chemical disposition of boron in animals and humans
- Review, NA, NA
*Half-Life↑, *other↑,
3880- Carno,    EFFECT OF ANSERINE/CARNOSINE SUPPLEMENTATION ON THE PREVENTION OF ALZHEIMER'S DISEASE IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT
- Trial, AD, NA
*cognitive↑, *other↑,
3700- Chol,    Eggs and Health Special Issue
- Review, Nor, NA
*other↑, *other↑, *Inflam↓, *ROS↓, *antiOx↑, *Iron↑, *cardioP∅,
1586- Citrate,    Extracellular Citrate Is a Trojan Horse for Cancer Cells
- in-vitro, Liver, HepG2
Dose?, ac‑H4↓, lipidDe↓, ACLY↓, selectivity↑, *ACLY∅, Glycolysis↓, NADH↓, OAA↑, other↑,
3994- CoQ10,  Se,    Coenzyme Q10 Supplementation in Aging and Disease
- Review, AD, NA - Review, Park, NA
*AntiAge↑, *cardioP↑, *Inflam↓, *antiOx↑, *lipid-P↓, *QoL↑, *neuroP↑, *Dose↝, *BP↓, *IGF-1↑, *IGFBP1↑, *eff↑, *LDL↓, *HDL↑, *eff↑, *other↑, *RenoP↑, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *other∅,
4770- CoQ10,  VitK2,    Cancer cell stiffening via CoQ10 and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer
- in-vitro, BC, MDA-MB-231
other↑, *antiOx↑, Risk↓, other↑, TumMeta↓, ECM/TCF↓, Akt2↓, Ferroptosis↑, eff↑,
3627- Croc,    The effects of Crocus sativus (saffron) and its constituents on nervous system: A review
- Review, AD, NA - Review, Stroke, NA
*other↑, *monoA↑, *Aβ↓, *AChE↓, *cognitive↑, *neuroP↑, *lipid-P↓, *SOD↑, *ROS↓, *GPx↑, *MDA↓, *memory↑, *antiOx↑, *Inflam↓, *other↓, *ER Stress↓,
1596- Cu,  CDT,    Unveiling the promising anticancer effect of copper-based compounds: a comprehensive review
- Review, NA, NA
TumCD↑, Apoptosis↓, ROS↑, angioG↑, Cupro↑, Paraptosis↑, eff↑, eff↓, selectivity↑, DNAdam↑, eff↑, eff↑, eff↑, eff↑, Fenton↑, H2O2↑, eff↑, eff↑, eff↑, RadioS↑, ChemoSen↑, eff↑, *toxicity↝, other↑, eff↑,
1570- Cu,    Development of copper nanoparticles and their prospective uses as antioxidants, antimicrobials, anticancer agents in the pharmaceutical sector
- Review, NA, NA
selectivity↑, antiOx↑, ROS↑, eff↑, GSH↓, lipid-P↑, Catalase↓, SOD↓, other↑,
2818- CUR,    Novel Insight to Neuroprotective Potential of Curcumin: A Mechanistic Review of Possible Involvement of Mitochondrial Biogenesis and PI3/Akt/ GSK3 or PI3/Akt/CREB/BDNF Signaling Pathways
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *Apoptosis↓, *cognitive↑, *cardioP↑, other↑, *COX2↓, *IL1β↓, *TNF-α↓, NF-kB↓, *PGE2↓, *iNOS↓, *NO↓, *IL2↓, *IL4↓, *IL6↓, *INF-γ↓, *GSK‐3β↓, *STAT↓, *GSH↑, *MDA↓, *lipid-P↓, *SOD↑, *GPx↑, *Catalase↑, *GSR↓, *LDH↓, *H2O2↓, *Casp3↓, *Casp9↓, *NRF2↑, *AIF↓, *ATP↑,
1872- DCA,    Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment
- in-vitro, Oral, HSC2 - in-vitro, Oral, HSC3
PDKs↓, ROS↑, OCR↑, other↑,
664- EGCG,  SNP,    Epigallocatechin-3-gallate-capped Ag nanoparticles: preparation and characterization
- Analysis, NA, NA
other↑,
678- EGCG,    Cancer Prevention with Green Tea and Its Principal Constituent, EGCG: from Early Investigations to Current Focus on Human Cancer Stem Cells
other↑, TumMeta↓, YMcells↑, CSCs↓,
3222- EGCG,    Epigallocatechin gallate and mitochondria—A story of life and death
- Review, Nor, NA
*lipid-P↓, *SOD↑, *Catalase↑, GPx↑, *GR↑, *GSTs↑, *GSH↑, *SIRT1↑, *PGC1A↑, *other↑,
3226- EGCG,    Epigallocatechin-3-gallate, a green-tea polyphenol, suppresses Rho signaling in TWNT-4 human hepatic stellate cells
- in-vitro, Nor, NA
*Rho↓, other↑,
4141- Ex,    Effects of exercise on brain-derived neurotrophic factor in Alzheimer's disease models: A systematic review and meta-analysis
- Review, AD, NA
*BDNF↑, *other↑, *eff↑,
4138- Ex,    Relationship Between Exercise and Alzheimer’s Disease: A Narrative Literature Review
- Review, AD, NA
*other↑, *Risk↓, *cognitive↑,
4069- FA,    Folate, folic acid and 5-methyltetrahydrofolate are not the same thing
- Review, AD, NA
*other↑, *BioAv↝, *other↝, *eff↑,
3716- FA,    Ferulic Acid as a Protective Antioxidant of Human Intestinal Epithelial Cells
- in-vitro, IBD, NA - in-vivo, NA, NA
*antiOx↑, *Inflam↓, *ER Stress↓, *other↑, *angioG↑, *Hif1a↑, *VEGF↑, *NO↓, *SIRT1↑, *PERK↓, *ATF4↓, *CHOP↓, *GutMicro↑,
4108- FLS,    Improvement of olfactory function in AD mice mediated by immune responses under 40 Hz light flickering
- in-vivo, AD, NA
*other↑,
4029- FulvicA,  Chemo,    Shilajit mitigates chemotherapeutic drug-induced testicular toxicity: Study on testicular germ cell dynamics, steroidogenesis modulation, and Nrf-2/Keap-1 signaling
- in-vivo, Var, NA
*other↑, *PCNA↑, *SOD↑, *lipid-P↓, *NRF2↑, *Keap1↓, *chemoP↑,
1636- GAR,    Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation
- Case Report, Obesity, NA
*Dose∅, *other↑,
1632- GAR,    Garcinia Cambogia, Either Alone or in Combination with Green Tea Causes Moderate to Severe Liver Injury
- Human, LiverDam, NA
HLA↑, other↑,
832- GAR,  Rad,    Garcinol, a Histone Acetyltransferase Inhibitor, Radiosensitizes Cancer Cells by Inhibiting Non-Homologous End Joining
- in-vitro, Lung, A549 - in-vitro, NA, HeLa
HATs↓, other↑,
4002- Gins,    Improvement of cognitive deficit in Alzheimer's disease patients by long term treatment with korean red ginseng
- Trial, AD, NA
*cognitive↑, *other↑,
851- Gra,    Antiproliferation Activity and Apoptotic Mechanism of Soursop (Annona muricata L.) Leaves Extract and Fractions on MCF7 Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vitro, Nor, CV1
Bcl-2↓, Casp9↑, Casp3↑, other↑, *toxicity↓,
846- Gra,    Cytotoxic effect of Annona muricata Linn leaves extract on Capan-1 cells
- in-vitro, NA, Ca9-22
other↑,
853- Gra,  SNP,    Solid lipid nanoparticles of Annona muricata fruit extract: formulation, optimization and in vitro cytotoxicity studies
other↑,
2529- H2,    Guidelines for the selection of hydrogen gas inhalers based on hydrogen explosion accidents
- Analysis, Nor, NA
other↑, eff↝, eff↝, other↝, other↝, other↝, other↝, other↝,
1415- HCA,    Hydroxycitrate delays early mortality in mice and promotes muscle regeneration while inducing a rich hepatic energetic status
- in-vivo, Nor, NA
*OS↑, *toxicity↓, *AST∅, *ALAT∅, *Strength↑, *memory∅, *other↑, *other↑, *other↑,
1634- HCA,    Hydroxycitrate: a potential new therapy for calcium urolithiasis
- Human, Nor, NA
*other↑, *eff↑,
4012- K+,    Abnormal potassium-channel function in platelets in Alzheimer's disease
- in-vivo, AD, NA
*other↑, *other↝,
4009- K+,    Na+ and K+ ion imbalances in Alzheimer’s disease
- Human, AD, NA
*other↝, *other↑,
1272- LA,    Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults
- Trial, Nor, NA
*Pain↓, *other↑,
867- Lae,    Effects of the Gut microbiota on Amygdalin and its use as an anti-cancer therapy: Substantial review on the key components involved in altering dose efficacy and toxicity
- Review, NA, NA
other↑,
861- Lae,  Chit,  SNP,    Synthesis of polygonal chitosan microcapsules for the delivery of amygdalin loaded silver nanoparticles in breast cancer therapy
other↑,
859- Lae,    Vitamin B17 and its Proposed Application in Treating Cancer
- Analysis, NA, NA
other↑,
870- Lae,    Physician Beware: Severe Cyanide Toxicity from Amygdalin Tablets Ingestion
- Case Report, NA, NA
other↑,
1790- LEC,  DHA,    Dietary Crude Lecithin Increases Systemic Availability of Dietary Docosahexaenoic Acid with Combined Intake in Rats
- in-vivo, Nor, NA
*eff↑, other↑,
1794- LEC,    Effects of abomasal infusion of soybean or sunflower lecithin on nutrient digestibility and milk production in lactating dairy cows
- in-vivo, NA, NA
BioAv↑, other↑,
3983- Lut,  Zeax,    The impact of supplemental macular carotenoids in Alzheimer's disease: a randomized clinical trial
- Trial, AD, NA
*other↑, *other↑, *cognitive∅,
3981- Lut,  Zeax,  VitE,    Omega-3 fatty acid, carotenoid and vitamin E supplementation improves working memory in older adults: A randomised clinical trial
- Trial, AD, NA
*memory↑, *other↑, *cognitive↑,
3979- Lut,    Increases in Plasma Lutein through Supplementation Are Correlated with Increases in Physical Activity and Reductions in Sedentary Time in Older Adults
- Trial, AD, NA
*other↑, *QoL↑,
3905- MCT,    Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer's disease. A systematic review and meta-analysis of human studies
- Review, AD, NA
*cognitive↑, *KeyT↑, *eff↑, *other↑, *toxicity↓,
1778- MEL,    Melatonin: a well-documented antioxidant with conditional pro-oxidant actions
- Review, Var, NA - Review, AD, NA
*ROS↓, *antiOx↓, ROS↑, selectivity↑, Dose↑, *mitResp↑, *ATP↑, *ROS↓, eff↑, ROS↑, Dose↑, *toxicity∅, ROS↑, eff↓, ROS↝, Dose↑, other↑,
4355- MF,    Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism
- in-vitro, Nor, C2C12
*mt-OCR↑, *mt-ROS↑, *ECAR↑, *Dose↝, *Ca+2↑, *ATP↑, *other↑, *eff↓, *eff↝,
3476- MF,    Pulsed Electromagnetic Fields Stimulate HIF-1α-Independent VEGF Release in 1321N1 Human Astrocytes Protecting Neuron-like SH-SY5Y Cells from Oxygen-Glucose Deprivation
- in-vitro, Stroke, 1321N1 - in-vitro, Park, NA
*VEGF↑, *eff↑, *neuroP↑, *other↑, *eff↑, *Inflam↓, *Hif1a∅,
3536- MF,    Targeting Mesenchymal Stromal Cells/Pericytes (MSCs) With Pulsed Electromagnetic Field (PEMF) Has the Potential to Treat Rheumatoid Arthritis
- Review, Arthritis, NA - Review, Stroke, NA
*Inflam↓, *Diff↑, *toxicity∅, *other↑, *SOX9↑, *COL2A1↑, *NO↓, *PGE2↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *IL6↓, *IL10↑, *angioG↑, *MSCs↑, *VEGF↑, *TGF-β↑, *angioG↝, *VEGF↓, Ca+2↝,
3474- MF,    Pulsed electromagnetic fields potentiate the paracrine function of mesenchymal stem cells for cartilage regeneration
- in-vitro, Nor, NA
*Inflam↓, *Apoptosis↓, *other↑, *PGE2↓, *COX2↓, *IL6↓, *IL8↓, *cAMP↑, *IL10↑,
3457- MF,    Cellular stress response to extremely low‐frequency electromagnetic fields (ELF‐EMF): An explanation for controversial effects of ELF‐EMF on apoptosis
- Review, Var, NA
Apoptosis↑, H2O2↑, ROS↑, eff↑, eff↑, Ca+2↑, MAPK↑, *Catalase↑, *SOD1↑, *GPx1↑, *GPx4↑, *NRF2↑, TumAuto↑, ER Stress↑, HSPs↑, SIRT3↑, ChemoSen↑, UPR↑, other↑, PI3K↓, JNK↑, p38↑, eff↓, *toxicity?,
3468- MF,    An integrative review of pulsed electromagnetic field therapy (PEMF) and wound healing
- Review, NA, NA
*other↑, *necrosis↓, *IL6↑, *TGF-β↑, *iNOS↑, *MMP2↑, *MCP1↑, *HO-1↑, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *BioAv↑, eff⇅, DNAdam↑, Apoptosis↑, ROS↑, TumCP↓, *ROS↓, *FGF↑,
3469- MF,    Pulsed Electromagnetic Fields (PEMF)—Physiological Response and Its Potential in Trauma Treatment
- Review, NA, NA
*eff↑, *eff↝, *other↑, Ca+2↑, ROS↑, HSP70/HSPA5↑, *NOTCH↑, *HEY1↑, *p38↑, *MAPK↑,
4117- MF,    Pulsed electromagnetic fields improve the healing process of Achilles tendinopathy: a pilot study in a rat model
- in-vivo, NA, NA
*other↑,
4149- MF,    Pulsed Electro-Magnetic Field (PEMF) Effect on Bone Healing in Animal Models: A Review of Its Efficacy Related to Different Type of Damage
- Review, NA, NA
*other↑, *BDNF↑, *BMPs↑, *BMD↑,
486- MF,    mTOR Activation by PI3K/Akt and ERK Signaling in Short ELF-EMF Exposed Human Keratinocytes
- in-vitro, Nor, HaCaT
*mTOR↑, *PI3K↑, *Akt↑, *p‑ERK↑, *other↑, *p‑JNK↑, *p‑P70S6K↑,
527- MF,    Effects of Fifty-Hertz Electromagnetic Fields on Granulocytic Differentiation of ATRA-Treated Acute Promyelocytic Leukemia NB4 Cells
- in-vitro, AML, APL NB4
ROS↑, other↑, p‑ERK↑, TumCP↓,
533- MF,    Effects of extremely low-frequency magnetic fields on human MDA-MB-231 breast cancer cells: proteomic characterization
- in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
TumCD↑, necrosis↑, mt-ROS↑, other↑, *STAT3↓, STAT3↑,
3535- MFrot,  MF,    Pulsed Electromagnetic Field Stimulation in Osteogenesis and Chondrogenesis: Signaling Pathways and Therapeutic Implications
- Review, Nor, NA
*eff↑, *COL2A1↑, *SOX9↑, *Ca+2↑, *FAK↑, *F-actin↑, *Inflam↓, *other↑, *Diff↑, *BMD↑,
2262- MFrot,  MF,    Effects of 0.4 T Rotating Magnetic Field Exposure on Density, Strength, Calcium and Metabolism of Rat Thigh Bones
- in-vivo, ostP, NA
*BMD↑, *eff↓, *ALP↑, *other↑,
788- Mg,    Timeline (Bioavailability) of Magnesium Compounds in Hours: Which Magnesium Compound Works Best?
other↑, other↑,
3807- mushLions,    Searching for a Longevity Food, We Bump into Hericium erinaceus Primordium Rich in Ergothioneine: The “Longevity Vitamin” Improves Locomotor Performances during Aging
*AntiAge↑, *other↑, *NOS2↓, *COX2↓, *P53↑, *neuroP↑,
2931- NAD,    NAD+ Repletion Rescues Female Fertility during Reproductive Aging
- in-vivo, Nor, NA
*eff↑, *SIRT2↑, *other↑, *Dose↝,
1812- Oxy,    Hyperbaric oxygen suppressed tumor progression through the improvement of tumor hypoxia and induction of tumor apoptosis in A549-cell-transferred lung cancer
- in-vitro, Lung, A549 - in-vivo, Lung, NA - in-vitro, NA, BEAS-2B
TumCG↓, CD31↑, P53↓, Dose∅, other↑, Apoptosis↑, Hif1a↑, selectivity↑,
1647- PBG,  CA,    Antioxidant Properties and Phenolic Composition of Greek Propolis Extracts
- Analysis, Nor, NA
Dose?, antiOx↑, other↑,
3595- PI,    Black pepper and health claims: a comprehensive treatise
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *chemoP↑, TumCG↓, *cognitive↑, *MMPs↓, *PGE2↓, *AP-1↓, *5LO↓, *COX1↓, *other↑, *other↑, *other↑, *SOD↑, *Catalase↑, *GSTs↑, *GSR↑, *other↑, *Weight↓, *BioEnh↑, *BioAv↑, *eff↑, *CYP3A2↓, *neuroP↑, *BP↓, *other↑,
4220- PI,    Piperine ameliorated memory impairment and myelin damage in lysolecethin induced hippocampal demyelination
- in-vivo, AD, NA - in-vivo, MS, NA
*memory↑, *iNOS↓, *NRF2↑, *HO-1↑, *TAC↑, *TNF-α↓, *IL1β↓, *NF-kB↓, *IL10↑, *FOXP3↑, *BDNF↑, other↑,
3917- PS,    Phosphatidylserine, inflammation, and central nervous system diseases
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *neuroP↑, *cognitive↑, *Choline↑, *IL1β↓, *IL6↓, *TNF-α↓, *Ach↑, *eff↑, *eff↑, *BioEnh↑, other↑,
3911- PS,  VitE,    Cognitive effects of a dietary supplement made from extract of Bacopa monnieri, astaxanthin, phosphatidylserine, and vitamin E in subjects with mild cognitive impairment: a noncomparative, exploratory clinical study
- Human, AD, NA
*cognitive↑, *other↑,
912- QC,  2DG,    Selected polyphenols potentiate the apoptotic efficacy of glycolytic inhibitors in human acute myeloid leukemia cell lines. Regulation by protein kinase activities
Apoptosis↑, ROS↓, GSH∅, other↑,
909- QC,    Exploring the therapeutic potential of quercetin in cancer treatment: Targeting long non-coding RNAs
- Review, NA, NA
other↓, other↑,
2439- RES,    By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice
- in-vitro, HCC, HCCLM3 - in-vitro, Nor, L02 - in-vitro, HCC, SMMC-7721 cell - in-vitro, HCC, Bel-7402 - in-vitro, HCC, HUH7
HK2↓, ChemoSen↑, other↑, Glycolysis↓, lactateProd↓, TumCP↓, Casp3↑, cl‑PARP↑, PKM2↓,
3099- RES,    Resveratrol and cognitive decline: a clinician perspective
- Review, Nor, NA - NA, AD, NA
*antiOx↑, *ROS↓, *cognitive↑, *neuroP↑, *SIRT1↑, *AMPK↑, *GPx↑, *HO-1↑, *GSK‐3β↑, *COX2↓, *PGE2↓, *NF-kB↓, *NO↓, *Casp3↓, *MMP3↓, *MMP9↓, *MMP↑, *GSH↑, *other↑, *BioAv↑, *memory↑, *GlutMet↑, *BioAv↓, *Half-Life↓, *toxicity∅,
3612- RES,    Resveratrol in Alzheimer's disease: a review of pathophysiology and therapeutic potential
- Review, AD, NA
*other↑, *Aβ↓, *Inflam↓, *NF-kB↓, *neuroP↑, *HO-1↑, *lipid-P↓, *COX2↓, *AMPK↑, *Catalase↑, *SOD↑, *GSR↑, *ROS↓, *MMP9↓, *cognitive↑, *SIRT1↑, *IL1β↓, *IL6↓,
3938- SAMe,    S-adenosyl-L-methionine in the treatment of Alzheimer's disease
- Human, AD, NA
*other↑,
4114- SAMe,    S-Adenosylmethionine (SAMe) for Neuropsychiatric Disorders: A Clinician-Oriented Review of Research
- Review, AD, NA
*Mood↑, *BBB↑, *5HT↑, *p‑tau↓, *Aβ↓, *other↑,
2549- SDT,    Landscape of Cellular Bioeffects Triggered by Ultrasound-Induced Sonoporation
- Review, Var, NA
sonoP↑, tumCV↓, MMP↓, ROS↑, Ca+2↑, eff↝, eff↑, selectivity↑, Half-Life↝, Dose↝, P-gp↓, ER Stress↑, other↑,
4214- Se,    Selenium ameliorates cognitive impairment through activating BDNF/TrkB pathway
- in-vivo, NA, NA
*memory↑, *other↑, *BDNF↑, *TrkB↑,
4728- Se,    Selective Impact of Selenium Compounds on Two Cytokine Storm Players
- NA, Covid, NA
*IL6↓, *TNF-α↓, *NRF2↑, *other↑, *eff↑,
1432- SFN,    Evaluation of biodistribution of sulforaphane after administration of oral broccoli sprout extract in melanoma patients with multiple atypical nevi
- Human, Melanoma, NA
other↑, decorin↑, *toxicity↓, IP-10/CXCL-10↓, MCP1↓, CXCL9↓, MIP-1β↓, IFN-γ↓,
3652- SIL,    Silibinin ameliorates anxiety/depression-like behaviors in amyloid β-treated rats by upregulating BDNF/TrkB pathway and attenuating autophagy in hippocampus
- in-vivo, NA, NA
*hepatoP↑, *other↑,
3291- SIL,    Antioxidant effects and mechanism of silymarin in oxidative stress induced cardiovascular diseases
- Review, Nor, NA
*antiOx↑, *ROS↓, *cardioP↑, *BioAv↓, *Half-Life↝, *other↑, IronCh↑,
4128- Silicon,    Silicon as Versatile Player in Plant and Human Biology: Overlooked and Poorly Understood
- Review, NA, NA
*other↑, *BMD↑, *Dose↝, *cognitive↑, *Dose?,
4126- Silicon,  H2,    Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method
- in-vivo, NA, NA
*creat↓, *ROS↓, *other↑, *MDA↓, *other↑, *Inflam↓,
3040- SK,    Pharmacological Properties of Shikonin – A Review of Literature since 2002
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA
*Half-Life↝, *BioAv↓, *BioAv↑, *BioAv↑, *Inflam↓, *TNF-α↓, *other↑, *MPO↓, *COX2↓, *NF-kB↑, *STAT3↑, *antiOx↑, *ROS↓, *neuroP↑, *SOD↑, *Catalase↑, *GPx↑, *Bcl-2↑, *BAX↓, cardioP↑, AntiCan↑, NF-kB↓, ROS↑, PKM2↓, TumCCA↑, Necroptosis↑, Apoptosis↑, DNAdam↑, MMP↓, Cyt‑c↑, LDH↝,
2007- SK,    Shikonin Directly Targets Mitochondria and Causes Mitochondrial Dysfunction in Cancer Cells
- in-vitro, lymphoma, U937 - in-vitro, BC, MCF-7 - in-vitro, BC, SkBr3 - in-vitro, CRC, HCT116 - in-vitro, OS, U2OS - NA, Nor, RPE-1
tumCV↓, selectivity↑, Dose↝, other↑, MMP↓, ROS↑, DNAdam↑, Ca+2↑, Casp9↑, Cyt‑c↑, *toxicity↓,
356- SNP,  MF,    Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study
- in-vitro, BC, MCF-7 - in-vitro, Bladder, HTB-22
Apoptosis↑, P53↑, iNOS↑, NF-kB↑, Bcl-2↓, ROS↑, SOD↑, TumCCA↑, eff↑, Catalase↑, other↑,
321- SNP,    I-131 doping of silver nanoparticles platform for tumor theranosis guided drug delivery
- in-vivo, NA, NA
other↑,
4562- SNP,  VitC,    Eco-friendly Synthesis of Silver Nanoparticles using Ascorbic Acid and its Optical Characterization
- Study, NA, NA
*other↑, *other↝,
4423- SNP,    Pongamia pinnata seed extract-mediated green synthesis of silver nanoparticle loaded nanogel for estimation of their antipsoriatic properties
- in-vivo, PSA, NA
*eff↑, *other↑,
4381- SNP,    Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells
- in-vitro, Liver, HepG2
eff↓, ROS↑, other↑,
4405- SNP,    Silver nanoparticles defeat p53-positive and p53-negative osteosarcoma cells by triggering mitochondrial stress and apoptosis
- in-vitro, OS, NA
Apoptosis↑, other↑, ROS↑, eff↑, P53↝, Apoptosis↑, cl‑Casp3↑, survivin↓, MMP↓, Cyt‑c↑,
3952- Taur,    Taurine and Astrocytes: A Homeostatic and Neuroprotective Relationship
- Review, AD, NA - Review, Stroke, NA
*antiOx↑, *Inflam↓, *Ca+2↓, *neuroP↑, *other↑, *Dose↝, *PKCδ↓, *VGCC↓, *GABA↑,
3959- Taur,    Taurine Directly Binds to Oligomeric Amyloid-β and Recovers Cognitive Deficits in Alzheimer Model Mice
- in-vivo, AD, NA
*cognitive↑, *Aβ∅, *other↑,
3960- Taur,    Versatile Triad Alliance: Bile Acid, Taurine and Microbiota
- Review, AD, NA - Review, Stroke, NA
*ROS↓, *Inflam↓, *GABA↑, *memory↑, *cognitive↑, *iNOS↓, *CRP↓, *HO-1↑, *Prx↑, *Trx↑, *NRF2↑, *GSH↑, *SOD↑, *Catalase↑, *lipid-P↓, *MDA↓, *eff↝, *GutMicro↑, other↑,
3961- Taur,    Effects of Dietary Taurine Supplementation on Blood and Urine Taurine Concentrations in the Elderly Women with Dementia
- Human, AD, NA
*other↑, *cognitive↑,
3962- Taur,    The Development of Taurine Supplementary Menus for the Prevention of Dementia and Their Positive Effect on the Cognitive Function in the Elderly with Dementia
- Human, AD, NA
*cognitive↑, *other↑,
3963- Taur,    Past Taurine Intake Has a Positive Effect on Present Cognitive Function in the Elderly
- Human, AD, NA
*Risk↓, *other↑,
4066- VitB12,  VitB6,  FA,    Vitamin B6, B12, and Folate’s Influence on Neural Networks in the UK Biobank Cohort
- Study, AD, NA
*other↓, *other↑, *other↑,
4045- VitB12,  FA,    Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial
- Trial, AD, NA
*homoC↓, *cognitive↑, *memory↑, *other↑,
4043- VitB12,  FA,    Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment
- Trial, AD, NA
*other↑, *other↑, *eff↝, *homoC↓, *cognitive↑,
4037- VitB12,  FA,    Mechanistic Link between Vitamin B12 and Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *ROS↓, *GSH↑, *Inflam↓, *IL6↓, *TNF-α↓, *other↑, *other↑, *other↑, *Aβ↓, *memory↑, *p‑tau↓, *APP↓, *BACE↓, *ATP↑, *neuroP↑,
4052- VitB6,    B-Vitamin Intake and Biomarker Status in Relation to Cognitive Decline in Healthy Older Adults in a 4-Year Follow-Up Study
- Study, AD, NA
*neuroP↑, *other↑, *other↑, *cognitive↑, *eff↝, *Risk↑, *other↑,
614- VitC,    Vitamin C Pharmacokinetics: Implications for Oral and Intravenous Use
other↑,
588- VitC,  MF,    Preparation of magnetic nanoparticle integrated nanostructured lipid carriers for controlled delivery of ascorbyl palmitate
other↑,
608- VitC,    The Levels of Ascorbic Acid in Blood and Mononuclear Blood Cells After Oral Liposome-Encapsulated and Oral Non-Encapsulated Vitamin C Supplementation, Taken Without and with IV Hydrocortisone
other↑, other↑,
3109- VitC,    Vitamin C Inhibited Pulmonary Metastasis through Activating Nrf2/HO-1 Pathway
- in-vitro, Lung, H1299
TumMeta↓, NRF2↑, HO-1↑, cl‑Casp3↑, cl‑Casp9↑, DNAdam↑, Apoptosis↑, other↑, selectivity↑,
4185- VitD3,    Effects of vitamin D supplementation on neuroplasticity in older adults: a double-blinded, placebo-controlled randomised trial
- Study, NA, NA
*other↑, *BDNF∅,
1833- VitK2,    Divergent effects of vitamins K1 and K2 on triple negative breast cancer cells
- in-vitro, BC, HS587T - in-vitro, BC, MDA-MB-231 - in-vitro, BC, SUM159
TumCP↓, other↑,
1817- VitK2,    Research progress on the anticancer effects of vitamin K2
- Review, Var, NA
TumCCA↑, Apoptosis↑, TumAuto↑, TumCI↓, TumCG↓, ChemoSen↓, ChemoSideEff↓, toxicity∅, eff↑, cycD1/CCND1↓, CDK4↓, eff↑, IKKα↓, NF-kB↓, other↑, p27↑, cMyc↓, i-ROS↑, Bcl-2↓, BAX↑, p38↑, MMP↓, Casp9↑, p‑ERK↓, RAS↓, MAPK↓, p‑P53↑, Casp8↑, Casp3↑, cJun↑, MMPs↓, eff↑, eff↑,
1757- WBV,    The Impact of Vibration Therapy Interventions on Skin Condition and Skin Temperature Changes in Young Women with Lipodystrophy: A Pilot Study
- Human, Nor, NA
Dose∅, other↑,
1752- WBV,  Chemo,    Feasibility of whole body vibration during intensive chemotherapy in patients with hematological malignancies – a randomized controlled pilot study
- Trial, Var, NA
*BP∅, eff↑, Dose∅, other↑, *toxicity∅, eff↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 122

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 2,   Catalase↓, 1,   Catalase↑, 1,   Fenton↑, 1,   Ferroptosis↑, 1,   GPx↑, 1,   GSH↓, 2,   GSH∅, 1,   H2O2↑, 2,   HO-1↑, 1,   lipid-P↑, 1,   lipidDe↓, 1,   NADH↓, 1,   NRF2↑, 1,   ROS↓, 1,   ROS↑, 19,   ROS↝, 1,   i-ROS↑, 1,   mt-ROS↑, 1,   SIRT3↑, 1,   SOD↓, 1,   SOD↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 5,   OCR↑, 1,  

Core Metabolism/Glycolysis ⓘ

ACLY↓, 1,   cMyc↓, 1,   Glycolysis↓, 2,   HK2↓, 1,   lactateProd↓, 1,   LDH↝, 1,   OAA↑, 1,   PDKs↓, 1,   PKM2↓, 2,  

Cell Death ⓘ

Apoptosis↓, 1,   Apoptosis↑, 11,   BAX↑, 1,   Bcl-2↓, 4,   Casp12↑, 1,   Casp3↑, 4,   cl‑Casp3↑, 2,   Casp8↑, 2,   Casp9↑, 4,   cl‑Casp9↑, 1,   Cupro↑, 1,   Cyt‑c↑, 4,   Fas↑, 1,   Ferroptosis↑, 1,   iNOS↑, 1,   JNK↑, 2,   MAPK↓, 1,   MAPK↑, 2,   Necroptosis↑, 1,   necrosis↑, 1,   p27↑, 1,   p38↑, 3,   Paraptosis↑, 1,   survivin↓, 1,   TumCD↑, 2,  

Transcription & Epigenetics ⓘ

cJun↑, 1,   ac‑H4↓, 1,   HATs↓, 1,   other↓, 1,   other↑, 56,   other↝, 5,   tumCV↓, 2,   YMcells↑, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↑, 2,   HSP70/HSPA5↑, 1,   HSPs↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 3,  

DNA Damage & Repair ⓘ

CHK1↓, 1,   DNAdam↑, 5,   P53↓, 1,   P53↑, 2,   P53↝, 1,   p‑P53↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence ⓘ

CDK4↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 1,   P21↑, 1,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State ⓘ

CSCs↓, 1,   ERK↓, 1,   p‑ERK↓, 1,   p‑ERK↑, 1,   PI3K↓, 1,   RAS↓, 1,   STAT3↓, 1,   STAT3↑, 1,   TumCG↓, 3,   Wnt↓, 1,  

Migration ⓘ

Akt2↓, 1,   AntiAg↑, 1,   Ca+2↑, 4,   Ca+2↝, 1,   CD31↑, 1,   decorin↑, 1,   p‑FAK↓, 1,   HLA↑, 1,   MALAT1↓, 1,   MMPs↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 4,   TumMeta↓, 3,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↑, 1,   ECM/TCF↓, 1,   Hif1a↓, 1,   Hif1a↑, 1,   VEGF↓, 1,   VEGFR2↓, 1,  

Barriers & Transport ⓘ

P-gp↓, 1,   sonoP↑, 1,  

Immune & Inflammatory Signaling ⓘ

CXCL9↓, 1,   IFN-γ↓, 1,   IKKα↓, 1,   IL8↓, 1,   Inflam↓, 1,   IP-10/CXCL-10↓, 1,   MCP1↓, 1,   MIP-1β↓, 1,   NF-kB↓, 3,   NF-kB↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 2,   ChemoSen↓, 1,   ChemoSen↑, 3,   Dose?, 2,   Dose↑, 3,   Dose↝, 3,   Dose∅, 3,   eff↓, 4,   eff↑, 25,   eff⇅, 1,   eff↝, 3,   Half-Life↝, 1,   RadioS↑, 1,   selectivity↑, 8,  

Clinical Biomarkers ⓘ

LDH↝, 1,  

Functional Outcomes ⓘ

AntiCan↑, 3,   cardioP↑, 1,   chemoP↑, 1,   ChemoSideEff↓, 1,   Risk↓, 1,   toxicity∅, 1,  
Total Targets: 148

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 2,   antiOx↑, 13,   Catalase↑, 7,   GPx↑, 5,   GPx1↑, 1,   GPx4↑, 1,   GSH↑, 7,   GSR↓, 1,   GSR↑, 2,   GSTs↑, 3,   H2O2↓, 1,   HDL↑, 2,   HO-1↑, 5,   Iron↑, 1,   Keap1↓, 2,   lipid-P↓, 8,   MDA↓, 6,   MPO↓, 2,   NRF2↑, 7,   Prx↑, 1,   ROS↓, 17,   mt-ROS↑, 1,   SOD↑, 10,   SOD1↑, 1,   TAC↑, 1,   TBARS↓, 1,   Trx↑, 1,   VitC↑, 1,  

Mitochondria & Bioenergetics ⓘ

AIF↓, 1,   ATP↑, 4,   mitResp↑, 1,   MMP↑, 1,   mt-OCR↑, 1,  

Core Metabolism/Glycolysis ⓘ

ACLY∅, 1,   adiP↓, 1,   ALAT↓, 1,   ALAT∅, 1,   AMPK↑, 2,   cAMP↑, 1,   CYP3A2↓, 1,   ECAR↑, 1,   GlutMet↑, 1,   H2S↑, 1,   homoC↓, 2,   KeyT↑, 1,   LDH↓, 3,   LDL↓, 2,   PGC1A↑, 1,   SIRT1↑, 4,   SIRT2↑, 1,  

Cell Death ⓘ

Akt↓, 1,   Akt↑, 1,   Apoptosis↓, 2,   BAX↓, 1,   Bcl-2↑, 1,   Casp3↓, 2,   Casp9↓, 1,   HEY1↑, 1,   iNOS↓, 4,   iNOS↑, 1,   p‑JNK↑, 1,   MAPK↑, 1,   necrosis↓, 1,   p38↑, 1,  

Kinase & Signal Transduction ⓘ

SOX9↑, 2,  

Transcription & Epigenetics ⓘ

Ach↑, 1,   other↓, 4,   other↑, 85,   other↝, 6,   other∅, 1,  

Protein Folding & ER Stress ⓘ

CHOP↓, 1,   ER Stress↓, 2,   PERK↓, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,   PCNA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

Choline↑, 1,   Diff↑, 2,   p‑ERK↑, 1,   FGF↑, 1,   GSK‐3β↓, 1,   GSK‐3β↑, 1,   IGF-1↑, 1,   IGFBP1↑, 1,   MSCs↑, 1,   mTOR↑, 1,   NOTCH↑, 1,   p‑P70S6K↑, 1,   PI3K↓, 1,   PI3K↑, 1,   STAT↓, 1,   STAT3↓, 1,   STAT3↑, 1,   VGCC↓, 1,  

Migration ⓘ

5LO↓, 1,   AP-1↓, 1,   APP↓, 1,   Ca+2↓, 1,   Ca+2↑, 2,   COL2A1↑, 2,   F-actin↑, 1,   FAK↑, 1,   MMP2↑, 1,   MMP3↓, 1,   MMP9↓, 2,   MMPs↓, 1,   PKCδ↓, 1,   Rho↓, 1,   TGF-β↑, 2,  

Angiogenesis & Vasculature ⓘ

angioG↑, 2,   angioG↝, 1,   ATF4↓, 1,   Hif1a↑, 1,   Hif1a∅, 1,   NO↓, 6,   VEGF↓, 1,   VEGF↑, 3,  

Barriers & Transport ⓘ

BBB?, 1,   BBB↑, 3,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 1,   COX2↓, 7,   CRP↓, 2,   FOXP3↑, 1,   IL10↑, 3,   IL1β↓, 7,   IL2↓, 1,   IL4↓, 1,   IL6↓, 10,   IL6↑, 1,   IL8↓, 1,   INF-γ↓, 1,   Inflam↓, 19,   MCP1↑, 1,   NF-kB↓, 5,   NF-kB↑, 1,   PGE2↓, 6,   TNF-α↓, 10,  

Synaptic & Neurotransmission other neurodegenerative diseases." style="cursor:help;color:#555;font-weight:normal;">ⓘ

5HT↑, 1,   AChE↓, 1,   BDNF↑, 4,   BDNF∅, 1,   GABA↑, 2,   monoA↑, 1,   p‑tau↓, 2,   TrkB↑, 1,  

Protein Aggregation other aggregation disorders." style="cursor:help;color:#555;font-weight:normal;">ⓘ

Aβ↓, 4,   Aβ∅, 1,   BACE↓, 1,  

Hormonal & Nuclear Receptors ⓘ

GR↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 3,   BioAv↑, 6,   BioAv↝, 1,   BioEnh↑, 2,   Dose?, 1,   Dose↝, 5,   Dose∅, 1,   eff↓, 5,   eff↑, 20,   eff↝, 6,   Half-Life↓, 1,   Half-Life↑, 2,   Half-Life↝, 3,  

Clinical Biomarkers otherapy eligibility | Immunotherapy | Gatekeeper for checkpoint use | | 5 | MSI | Tumor-agnostic immunotherapy | Immunotherapy | One of the strongest predictors of IO response | | 6 | BRAF | Targeted therapy | Target selection | Direct, mutation-specific action | | 7 | BRCA1 / BRCA2 | PARP inhibitor use | Target selection | Therapy + inherited risk | | 8 | ALK | Fusion-targeted therapy | Target selection | Dramatic response when positive | | 9 | AR | Prostate therapy backbone | Target selection | Defines entire disease class | | 10 | ESR1 | Endocrine therapy | Target selection | Absolute requirement in breast cancer | Mid-Tier: Strong but Contextual Decision Impact | Rank | Biomarker | Primary Use | Clinical Class | Notes | | ---- | ------------- | ----------------------- | ---------------- | ----------------------------- | | 11 | NTRK (fusion) | Tumor-agnostic therapy | Target selection | Rare but decisive | | 12 | PSA | Monitoring, progression | Monitoring | Drives treatment timing | | 13 | B2M | Staging & prognosis | Immunotherapy | Used in myeloma/lymphoma | | 14 | TP53 | Risk stratification | Aggressiveness | Alters intensity, trials | | 15 | WT1 | MRD monitoring | Monitoring | Highly actionable in leukemia | | 16 | Ki-67 | Growth rate | Aggressiveness | Influences therapy escalation | | 17 | CA-125 | Therapy response | Monitoring | Standard ovarian tracking | | 18 | CEA | Recurrence detection | Monitoring | Common but nonspecific | Lower-Tier: Indirect / Emerging / Contextual Impact | Rank |Biomarker| Primary Role | Clinical Class | Why Lower | | ---- | ------- | ---------------------- | ---------------- | -------------------------- | | 19 | AFP | Diagnosis/monitoring | Monitoring | Cancer-specific contexts | | 20 | CA 19-9 | Disease burden | Monitoring | Prognostic, not directive | | 21 | MYC | Risk biology | Aggressiveness | Not directly actionable | | 22 | TERT | Prognosis | Aggressiveness | Rarely changes therapy | | 23 | EZH2 | Epigenetic state | Aggressiveness | Select indications | | 24 | SUZ12 | PRC2 dependency | Aggressiveness | Indirect | | 25 | RBM3 | Prognostic | Aggressiveness | Informative, not directive | | 26 | OPG | Bone microenvironment | Microenvironment | Supportive info | | 27 | RAGE | Inflammation state | Microenvironment | Research-stage | | 28 | XIST | Epigenetic instability | Aggressiveness | Not yet clinical | | 29 | FOXM1 | High-risk biology | Aggressiveness | No routine testing | | 30 | TRIB3 | Stress adaptation | Aggressiveness | Mechanistic, not clinical | Core Liver & Systemic Biomarkers in Oncology | Marker | What It Reflects | Main Use in Cancer | Decision Impact | | --------- | ----------------------------------- | ----------------------------------------- | ----------- | | ALT | Hepatocellular injury | Baseline eligibility, toxicity monitoring | High | | AST | Liver + systemic injury | Detect liver injury, muscle involvement | High | | ALP | Cholestasis, bone turnover | Liver mets vs bone mets | High | | bilirubin | Hepatic clearance | Chemotherapy dosing | Critical | | albumin | Synthetic liver function, nutrition | Prognosis, frailty | High | | LDH | Tumor burden, hypoxia | Aggressiveness, prognosis | High | | INR | Liver synthetic failure | Treatment safety | High | Key Inflammatory / Host-Response Biomarkers Used in Oncology | Biomarker | What It Reflects | Main Use in Cancer | Clinical Decision Impact | | ------------------ | -------------------------------- | ---------------------------- | -------------------- | | C-reactive protein | Systemic inflammation | Prognosis, therapy tolerance | High | | ESR | Chronic inflammation | Disease activity trend | Moderate | | ferritin | Inflammation + iron status | Cachexia, cytokine load | High | | IL-6 | Cytokine signaling | Aggressiveness, cachexia | High (specialty use) | | LDH | Tumor burden + hypoxia | Risk stratification | Very high | | albumin | Nutritional & inflammatory state | Frailty, survival | Very high | </pre> " style="cursor:help;color:#555;font-weight:normal;">ⓘ

ALAT↓, 1,   ALAT∅, 1,   ALP↑, 1,   AST↓, 1,   AST∅, 1,   BMD↑, 4,   BMPs↑, 1,   BP↓, 3,   BP∅, 1,   creat↓, 2,   CRP↓, 2,   GutMicro↑, 4,   IL6↓, 10,   IL6↑, 1,   LDH↓, 3,   NOS2↓, 1,  

Functional Outcomes ⓘ

AntiAge↑, 2,   BOLD↑, 1,   cardioP↑, 5,   cardioP∅, 1,   chemoP↑, 2,   cognitive↓, 1,   cognitive↑, 24,   cognitive∅, 2,   hepatoP↑, 2,   memory↑, 10,   memory∅, 1,   Mood↑, 1,   neuroP↓, 1,   neuroP↑, 16,   OS↑, 1,   Pain↓, 1,   QoL↑, 2,   RenoP↑, 1,   Risk↓, 5,   Risk↑, 2,   Strength↑, 1,   toxicity?, 1,   toxicity↓, 5,   toxicity↝, 1,   toxicity∅, 4,   Weight↓, 1,  
Total Targets: 203

Scientific Paper Hit Count for: other, other
16 Magnetic Fields
9 Silver-NanoParticles
6 Folic Acid
6 Vitamin C (Ascorbic Acid)
6 Taurine
5 Vitamin B12
4 EGCG (Epigallocatechin Gallate)
4 Laetrile B17 Amygdalin
3 Allicin (mainly Garlic)
3 Selenium
3 Vitamin K2
3 Garcinol
3 Graviola
3 Lutein
3 Resveratrol
2 Sulforaphane (mainly Broccoli)
2 Boron
2 Coenzyme Q10
2 Copper and Cu NanoParticlex
2 Exercise
2 Chemotherapy
2 Hydrogen Gas
2 HydroxyCitric Acid
2 Potassium
2 Lecithin
2 Zeaxanthin
2 Vitamin E
2 Magnetic Field Rotating
2 Piperine
2 Phosphatidylserine
2 Quercetin
2 S-adenosyl-L-methionine
2 Silymarin (Milk Thistle) silibinin
2 Silicic Acid
2 Shikonin
2 Vitamin B6,pyridoxine
2 Whole Body Vibration
1 Serotonin, 5-hydroxytryptamine
1 dietMediterranean
1 Anthocyanins
1 Alpha-Lipoic-Acid
1 Aluminum
1 Aromatherapy
1 Biochanin A
1 Bacopa monnieri
1 Carnosine
1 Choline
1 Citric Acid
1 Crocetin
1 chemodynamic therapy
1 Curcumin
1 Dichloroacetate
1 Ferulic acid
1 Flickering Light Stimulation
1 Shilajit/Fulvic Acid
1 Radiotherapy/Radiation
1 Ginseng
1 Lactobacillus
1 chitosan
1 Docosahexaenoic Acid
1 MCToil
1 Melatonin
1 Magnesium
1 Mushroom Lion’s Mane
1 nicotinamide adenine dinucleotide
1 Oxygen, Hyperbaric
1 Propolis -bee glue
1 Caffeic acid
1 2-DeoxyGlucose
1 SonoDynamic Therapy UltraSound
1 Vitamin D3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:767  State#:0  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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