Database Query Results : , , SAM-e

SAM-e, S-adenosylmethionine: Click to Expand ⟱
Source:
Type:
S-adenosylmethionine (SAM-e) is a naturally occurring compound that plays a crucial role in various cellular processes, including methylation, gene expression, and cell growth. SAM-e has been studied for its potential anti-cancer effects, and some research suggests that it may have a role in cancer prevention and treatment.
Properties:
-Inhibition of cancer cell growth
-Induction of apoptosis
-Inhibition of angiogenesis
-Modulation of epigenetic marks: SAM-e is involved in the regulation of epigenetic marks, such as DNA methylation and histone modification
-Antioxidant and anti-inflammatory effects

SAM-e expression decreased in: Liver, Breast, CRC, prostate, GC, ESo, Pancreatic
SAM-e expressing is increased in: Lung, Pancreatic, Ovarian, Melanoma, Thyroid, Renal GBM
Scientific Papers found: Click to Expand⟱
698- Bor,    Boron deprivation decreases liver S-adenosylmethionine and spermidine and increases plasma homocysteine and cysteine in rats
- in-vitro, NA, NA
SAM-e↑,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Results for Effect on Cancer/Diseased Cells:
angioG↓,1,   AntiCan↑,1,   Apoptosis↑,1,   Cyc↓,1,   HDAC↓,1,   HIF-1↓,1,   IGF-1↓,1,   PSA↓,1,   Risk↓,1,   SAM-e↑,1,   TumCMig↓,1,   TumVol↓,1,  
Total Targets: 12

Results for Effect on Normal Cells:
ATP↝,1,   BMD↑,1,   BMPs↑,1,   Ca+2↝,1,   Calcium↑,1,   Catalase↑,1,   chemoP↑,1,   ChemoSideEff↓,1,   cognitive↑,1,   Dose↑,1,   Dose↝,1,   eff↑,1,   GPx↑,1,   hs-CRP↓,1,   Inflam↓,1,   Mag↑,1,   memory↑,1,   NAD↝,1,   neuroP↑,1,   Risk↓,1,   SAM-e↑,1,   selectivity↑,1,   serineP↓,1,   SOD↑,1,   testos↑,1,   TNF-α↓,1,   VitD↑,1,  
Total Targets: 27

Scientific Paper Hit Count for: SAM-e, S-adenosylmethionine
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:849  State#:0  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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