Database Query Results : , , VitD

VitD, Vitamin D: Click to Expand ⟱
Source:
Type:
Vitamin D expression is decreased in: Breast, CRC, Prostate, Lung, Melanoma, GBM, Pancreatic cancer. (Poor prognosis, with decreased overall survival).
Vitamin D expression is increased in RCC, Thyroid, Ovarian, Endometrial, Cervical cancers (***Better prognosis, with increased overall survival).

See VDR and CYP27B1.
CYP27B1 is the enzyme responsible for converting 25‐hydroxyvitamin D into its active form, 1,25‐dihydroxyvitamin D (calcitriol). As with VDR, CYP27B1 expression in tumors has been investigated for its potential prognostic significance in various cancers.
Scientific Papers found: Click to Expand⟱
3518- Bor,    Boron Report
- Review, Var, NA - Review, AD, NA
Risk↓, serineP↓, PSA↓, TumVol↓, IGF-1↓, *Mag↑, *Calcium↑, *VitD↑, *COX2↓, *5LO↓, *PGE2↓, *NF-kB↓, *cognitive↑,
3502- Bor,    Plasma boron concentrations in the general population: a cross-sectional analysis of cardio-metabolic and dietary correlates
- Review, NA, NA
*Half-Life↑, *VitD↑, *cardioP↑, *RenoP↓,
758- Bor,    Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
- Human, NA, NA
*hs-CRP↓, *TNF-α↓, *SHBG↓, *DHT↑, *cortisol↑, *VitD↑, *BioAv↑, *Inflam↓,
759- Bor,    The nutritional and metabolic effects of boron in humans and animals
- in-vivo, NA, NA
DHT↑, VitD↑, HDL↓,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑,
787- Mg,    Magnesium and Human Health: Perspectives and Research Directions
VitD↑, other↓,
786- Mg,  VitC,    A narrative review on the role of magnesium in immune regulation, inflammation, infectious diseases, and cancer
Risk↓, *VitD↑, *pH↝, *ROS↓, TumCG↓, eff↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7

Results for Effect on Cancer/Diseased Cells:
angioG↓,1,   AntiCan↑,1,   Apoptosis↑,1,   Cyc↓,1,   DHT↑,1,   eff↑,1,   HDAC↓,1,   HDL↓,1,   HIF-1↓,1,   IGF-1↓,2,   other↓,1,   PSA↓,2,   Risk↓,3,   serineP↓,1,   TumCG↓,1,   TumCMig↓,1,   TumVol↓,2,   VitD↑,2,  
Total Targets: 18

Results for Effect on Normal Cells:
5LO↓,1,   ATP↝,1,   BioAv↑,1,   BMD↑,1,   BMPs↑,1,   Ca+2↝,1,   Calcium↑,2,   cardioP↑,1,   Catalase↑,1,   chemoP↑,1,   ChemoSideEff↓,1,   cognitive↑,2,   cortisol↑,1,   COX2↓,1,   DHT↑,1,   Dose↑,1,   Dose↝,1,   eff↑,1,   GPx↑,1,   Half-Life↑,1,   hs-CRP↓,2,   Inflam↓,2,   Mag↑,2,   memory↑,1,   NAD↝,1,   neuroP↑,1,   NF-kB↓,1,   PGE2↓,1,   pH↝,1,   RenoP↓,1,   Risk↓,1,   ROS↓,1,   SAM-e↑,1,   selectivity↑,1,   serineP↓,1,   SHBG↓,1,   SOD↑,1,   testos↑,1,   TNF-α↓,2,   VitD↑,5,  
Total Targets: 40

Scientific Paper Hit Count for: VitD, Vitamin D
5 Boron
2 Magnesium
1 Vitamin C (Ascorbic Acid)
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:851  State#:0  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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