Database Query Results : Selenium, ,

Se, Selenium: Click to Expand ⟱
Features: micronutrient
Naturally occurring element

-recommended daily allowance (RDA) for selenium is about 55 µg/day for adults.
-One Brazil nut may contain 50-300ug/nut
Scientific Papers found: Click to Expand⟱
3517- Bor,  Se,    The protective effects of selenium and boron on cyclophosphamide-induced hepatic oxidative stress, inflammation, and apoptosis in rats
- in-vivo, Nor, NA
*hepatoP↑, *ALAT↓, *AST↓, *ALP↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *IL6↓, *IL10↑, *SOD↑, *Catalase↑, *MDA↓, *GSH↑, *GPx↑, *antiOx↑, *NRF2↑, *Keap1↓,
2806- CHr,  Se,    Selenium-containing chrysin and quercetin derivatives: attractive scaffolds for cancer therapy
- in-vitro, Var, NA
eff↑, selectivity↑, Dose↝, TrxR↓, GSH↓, MMP↓, ROS↑, H2O2↑,
3994- CoQ10,  Se,    Coenzyme Q10 Supplementation in Aging and Disease
- Review, AD, NA - Review, Park, NA
*AntiAge↑, *cardioP↑, *Inflam↓, *antiOx↑, *lipid-P↓, *QoL↑, *neuroP↑, *Dose↝, *BP↓, *IGF-1↑, *IGFBP1↑, *eff↑, *LDL↓, *HDL↑, *eff↑, *other↑, *RenoP↑, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *other∅,
641- EGCG,  Se,    Antioxidant effects of green tea
ROS↑, H2O2↑, ROS⇅,
4216- Se,    Selenium ameliorates mercuric chloride-induced brain damage through activating BDNF/TrKB/PI3K/AKT and inhibiting NF-κB signaling pathways
- in-vitro, NA, NA
*BDNF↑, *TrkB↓, *PI3K↑, *Akt↑, *neuroP↑,
4214- Se,    Selenium ameliorates cognitive impairment through activating BDNF/TrkB pathway
- in-vivo, NA, NA
*memory↑, *other↑, *BDNF↑, *TrkB↑,
4085- Se,    Role of micronutrients in Alzheimer's disease: Review of available evidence
- Review, AD, NA
*AChE↓, *BChE↓, *antiOx↑, *memory↑, *cognitive↑,
2142- Se,    A U-shaped association between selenium intake and cancer risk
- Review, NA, NA
*Risk↝, Dose↝, *Risk↓,
2141- Se,    Selenium and cancer risk: Wide-angled Mendelian randomization analysis
- Review, NA, NA
Dose↝, Risk↝,
2140- Se,    Selenium Exposure and Cancer Risk: an Updated Meta-analysis and Meta-regression
- Review, Var, NA
Risk↓, antiOx↑, eff↑, eff↝,
1707- Se,    A Diet Lacking Selenium, but Not Zinc, Copper or Manganese, Induces Anticancer Activity in Mice with Metastatic Cancers
- in-vivo, Ovarian, NA - in-vivo, BC, NA
OS↓,
1706- Se,    Selenium in Prostate Cancer: Prevention, Progression, and Treatment
- Review, Pca, NA
Risk∅, ChemoSen↑, Risk↓, toxicity↝, Risk↑, eff↑, *toxicity↑, RadioS↑, eff↓, eff↑, ChemoSen↑, ChemoSideEff↓,
1705- Se,    Serum Selenium Level and 10-Year Survival after Melanoma
- Study, Melanoma, NA
OS↑,
1704- Se,    Prospective study of toenail selenium levels and cancer among women
- Study, Var, NA
Risk∅,
1703- Se,    An Assessment of Serum Selenium Concentration in Women with Endometrial Cancer
- Study, EC, NA
Risk↓, selm↝,
1702- Se,    Supplemental Selenium May Decrease Ovarian Cancer Risk in African-American Women
- Human, Ovarian, NA
Risk↓, eff∅,
1700- Se,    Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers
- Review, Var, NA
Dose↝, Risk↑, Dose↝, Risk↓,
1687- Se,    Selenium for preventing cancer
- Analysis, Var, NA
eff∅, AntiCan∅,
1688- Se,    Potential Role of Selenium in the Treatment of Cancer and Viral Infections
- Review, Var, NA
IL2↑, INF-γ↑, Th1 response↑, Th2↑, Dose↑, AntiCan∅, Risk↑, chemoP↑, Hif1a↓, VEGF↓, selectivity↑, *GADD45A↑, NRF2↓, *NRF2↑, ChemoSen↑, angioG↓, PrxI↓, ChemoSideEff↓, eff↑,
1689- Se,    Selenium and breast cancer - An update of clinical and epidemiological data
- Analysis, BC, NA
OS↑, eff↑, Dose∅, *toxicity↝, eff↑,
1690- Se,    Selenium and cancer: a story that should not be forgotten-insights from genomics
- Review, Var, NA
Dose↓, other↝,
1691- Se,    The influence of selenium and selenoprotein gene variants on colorectal cancer risk
- Analysis, CRC, NA
Risk↓,
1692- Se,    Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status
- Analysis, CRC, NA
Risk↓,
1693- Se,    Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study
- Analysis, BC, NA
Risk↓, other∅,
1694- Se,    Expression of Selenoprotein Genes and Association with Selenium Status in Colorectal Adenoma and Colorectal Cancer
- Analysis, CRC, NA
AntiCan↑, selenoP↓,
1695- Se,    Serum Selenium Concentration as a Potential Diagnostic Marker for Early-Stage Colorectal Cancer: A Comparative Study
- Trial, CRC, NA
Risk↓, selm↑, Dose↓, antiOx↑, Dose↑, Dose↝,
1696- Se,    Selenium dietary intake and survival among CRC patients
- Human, CRC, NA
OS↑,
1697- Se,  Calc,    Calcium intake may explain the reduction of colorectal cancer odds by dietary selenium - a case-control study in Poland
- Human, CRC, NA
Risk↓, Risk↓, Dose∅, AntiCan↑,
1698- Se,    Association between Dietary Zinc and Selenium Intake, Oxidative Stress-Related Gene Polymorphism, and Colorectal Cancer Risk in Chinese Population - A Case-Control Study
- Human, CRC, NA
Risk↓,
1699- Se,    Vegetarianism and colorectal cancer risk in a low-selenium environment: effect modification by selenium status? A possible factor contributing to the null results in British vegetarians
- Analysis, CRC, NA
Dose↑, eff↓, Dose↓,
1701- Se,    An Assessment of Serum Selenium Concentration in Women with Ovarian Cancer
- Human, Ovarian, NA
Risk↓, Risk↓, Dose∅,
3406- TQ,  Se,    A study to determine the effect of nano-selenium and thymoquinone on the Nrf2 gene expression in Alzheimer’s disease
- in-vivo, AD, NA
*NRF2↑, *GSH↑, *MDA↓, *TNF-α↓,
609- VitC,  ALA,  VitK3,  Se,    Vitamin C and Cancer: Is There A Use For Oral Vitamin C?
OS↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 33

Results for Effect on Cancer/Diseased Cells:
angioG↓,1,   AntiCan↑,2,   AntiCan∅,2,   antiOx↑,2,   chemoP↑,1,   ChemoSen↑,3,   ChemoSideEff↓,2,   Dose↓,3,   Dose↑,3,   Dose↝,6,   Dose∅,3,   eff↓,2,   eff↑,7,   eff↝,1,   eff∅,2,   GSH↓,1,   H2O2↑,2,   Hif1a↓,1,   IL2↑,1,   INF-γ↑,1,   MMP↓,1,   NRF2↓,1,   OS↓,1,   OS↑,4,   other↝,1,   other∅,1,   PrxI↓,1,   RadioS↑,1,   Risk↓,14,   Risk↑,3,   Risk↝,1,   Risk∅,2,   ROS↑,2,   ROS⇅,1,   selectivity↑,2,   selenoP↓,1,   selm↑,1,   selm↝,1,   Th1 response↑,1,   Th2↑,1,   toxicity↝,1,   TrxR↓,1,   VEGF↓,1,  
Total Targets: 43

Results for Effect on Normal Cells:
AChE↓,1,   Akt↑,1,   ALAT↓,1,   ALP↓,1,   AntiAge↑,1,   antiOx↑,3,   AST↓,1,   BChE↓,1,   BDNF↑,2,   BP↓,1,   cardioP↑,1,   Catalase↑,1,   cognitive↑,1,   Dose↝,1,   eff↑,2,   GADD45A↑,1,   GPx↑,1,   GSH↑,2,   HDL↑,1,   hepatoP↑,1,   IGF-1↑,1,   IGFBP1↑,1,   IL10↑,1,   IL1β↓,1,   IL6↓,2,   Inflam↓,1,   Keap1↓,1,   LDL↓,1,   lipid-P↓,1,   MDA↓,2,   memory↑,2,   neuroP↑,2,   NF-kB↓,1,   NRF2↑,3,   other↑,2,   other↝,1,   other∅,1,   PI3K↑,1,   QoL↑,1,   RenoP↑,1,   Risk↓,1,   Risk↝,1,   ROS↓,1,   SOD↑,1,   TNF-α↓,3,   toxicity↑,1,   toxicity↝,1,   TrkB↓,1,   TrkB↑,1,  
Total Targets: 49

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:149  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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