Database Query Results : Vitamin B12, , SAM-e

VitB12, Vitamin B12: Click to Expand ⟱
Features:
Helps make red blood cells, metabolize food and prevent nerve damage.
SAM-e, S-adenosylmethionine: Click to Expand ⟱
Source:
Type:
S-adenosylmethionine (SAM-e) is a naturally occurring compound that plays a crucial role in various cellular processes, including methylation, gene expression, and cell growth. SAM-e has been studied for its potential anti-cancer effects, and some research suggests that it may have a role in cancer prevention and treatment.
Properties:
-Inhibition of cancer cell growth
-Induction of apoptosis
-Inhibition of angiogenesis
-Modulation of epigenetic marks: SAM-e is involved in the regulation of epigenetic marks, such as DNA methylation and histone modification
-Antioxidant and anti-inflammatory effects

SAM-e expression decreased in: Liver, Breast, CRC, prostate, GC, ESo, Pancreatic
SAM-e expressing is increased in: Lung, Pancreatic, Ovarian, Melanoma, Thyroid, Renal GBM
Scientific Papers found: Click to Expand⟱
4053- VitB12,  VitB6,  FA,    Vitamins in Alzheimer’s Disease—Review of the Latest Reports
- Review, AD, NA
*cognitive↑, A diet rich in antioxidant vitamins can improve the cognitive functions of patients
*homoC↓, Vitamin B12 is involved in the transformation of homocysteine to methionine, and vitamin B6 and folic acid are cofactors for this reaction.
*SAM-e↓, This reduces the concentration of S-adenosylmethionine, which is a methyl donor.


* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Results for Effect on Cancer/Diseased Cells:

Total Targets: 0

Results for Effect on Normal Cells:
cognitive↑,1,   homoC↓,1,   SAM-e↓,1,  
Total Targets: 3

Scientific Paper Hit Count for: SAM-e, S-adenosylmethionine
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:165  Target#:849  State#:%  Dir#:%
  wNotes=on  sortOrder:rid,rpid

 

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