PDT, Photodynamic Therapy: Click to Expand ⟱
Features: Therapy
Photodynamic therapy is a form of phototherapy involving light and a photosensitizing chemical substance used in conjunction with molecular oxygen to elicit cell death.


Scientific Papers found: Click to Expand⟱
1374- BBR,  PDT,    Berberine associated photodynamic therapy promotes autophagy and apoptosis via ROS generation in renal carcinoma cells
- in-vitro, RCC, 786-O - in-vitro, RCC, HK-2
ROS↑, TumAuto↑, Apoptosis↑, Casp3↑, eff↑,
2680- BBR,  PDT,    Photodynamic therapy-triggered nuclear translocation of berberine from mitochondria leads to liver cancer cell death
- in-vitro, Liver, HUH7
TumCD↑, ROS↑, TumCCA↑, ER Stress↑,
2681- BBR,  PDT,    Berberine-photodynamic induced apoptosis by activating endoplasmic reticulum stress-autophagy pathway involving CHOP in human malignant melanoma cells
- in-vitro, Melanoma, NA
Apoptosis↑, cl‑Casp3↑, LC3s↑, ER Stress↑, ROS↑, CHOP↑,
482- CUR,  PDT,    The Antitumor Effect of Curcumin in Urothelial Cancer Cells Is Enhanced by Light Exposure In Vitro
- in-vitro, Bladder, RT112 - in-vitro, Bladder, UMUC3
Apoptosis↑, TumCG↓, TumCP↓,
483- CUR,  PDT,    Visible light and/or UVA offer a strong amplification of the anti-tumor effect of curcumin
- in-vivo, NA, A431
TumVol↓, TumCP↓, Apoptosis↑,
484- CUR,  PDT,    Low concentrations of curcumin induce growth arrest and apoptosis in skin keratinocytes only in combination with UVA or visible light
- in-vitro, Melanoma, NA
Cyt‑c↑, Casp9↑, Casp8↑, NF-kB↓, EGFR↓,
485- CUR,  PDT,    Red Light Combined with Blue Light Irradiation Regulates Proliferation and Apoptosis in Skin Keratinocytes in Combination with Low Concentrations of Curcumin
- in-vitro, Melanoma, NA
NF-kB↓, Casp8↑, Casp9↑, p‑Akt↓, p‑ERK↓,
1175- IVM,  PDT,    Drug induced mitochondria dysfunction to enhance photodynamic therapy of hypoxic tumors
- in-vitro, Var, NA
Hypoxia↓, mitResp↓, ROS↑,
2532- M-Blu,  PDT,    Methylene blue in anticancer photodynamic therapy: systematic review of preclinical studies
- Review, Var, NA
AntiCan↑,
2533- M-Blu,  PDT,    Methylene blue-mediated photodynamic therapy enhances apoptosis in lung cancer cells
- in-vitro, Lung, A549
MMP↓, p‑MAPK↑, ROS↑, cl‑PARP↑, Bcl-2↓, Mcl-1↓, eff↓,
2534- M-Blu,  doxoR,  PDT,    Methylene Blue-Mediated Photodynamic Therapy in Combination With Doxorubicin: A Novel Approach in the Treatment of HT-29 Colon Cancer Cells
- in-vitro, CRC, HT-29
LDH↑, ROS↑,
1476- SFN,  PDT,    Enhancement of cytotoxic effect on human head and neck cancer cells by combination of photodynamic therapy and sulforaphane
- in-vitro, HNSCC, NA
eff↑, tumCV↓, ROS↑, eff↓, Casp↑,
335- SNP,  PDT,    Biogenic Silver Nanoparticles for Targeted Cancer Therapy and Enhancing Photodynamic Therapy
- Review, NA, NA
ROS↑, GSH↓, GPx↑, Catalase↓, SOD↓, p38↑, BAX↑, Bcl-2↓,
336- SNP,  PDT,    Photodynamic ability of silver nanoparticles in inducing cytotoxic effects in breast and lung cancer cell lines
- in-vitro, BC, MCF-7
Apoptosis↑,
1834- VitK3,  PDT,    Effects of Vitamin K3 Combined with UVB on the Proliferation and Apoptosis of Cutaneous Squamous Cell Carcinoma A431 Cells
- in-vitro, Melanoma, A431
eff↑, TumCG↓, TumCP↓, ROS↑, MMP↓,
1838- VitK3,  PDT,    Photodynamic Effects of Vitamin K3 on Cervical Carcinoma Cells Activating Mitochondrial Apoptosis Pathways
- in-vitro, Cerv, NA
eff↑, ROS↑, tumCV↓, TumCG↓, Apoptosis↑, cl‑Casp3↑, cl‑Casp9↑, Bcl-xL↑, Cyt‑c↑, Bcl-2↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 16

Results for Effect on Cancer/Diseased Cells:
p‑Akt↓,1,   AntiCan↑,1,   Apoptosis↑,6,   BAX↑,1,   Bcl-2↓,3,   Bcl-xL↑,1,   Casp↑,1,   Casp3↑,1,   cl‑Casp3↑,2,   Casp8↑,2,   Casp9↑,2,   cl‑Casp9↑,1,   Catalase↓,1,   CHOP↑,1,   Cyt‑c↑,2,   eff↓,2,   eff↑,4,   EGFR↓,1,   ER Stress↑,2,   p‑ERK↓,1,   GPx↑,1,   GSH↓,1,   Hypoxia↓,1,   LC3s↑,1,   LDH↑,1,   p‑MAPK↑,1,   Mcl-1↓,1,   mitResp↓,1,   MMP↓,2,   NF-kB↓,2,   p38↑,1,   cl‑PARP↑,1,   ROS↑,10,   SOD↓,1,   TumAuto↑,1,   TumCCA↑,1,   TumCD↑,1,   TumCG↓,3,   TumCP↓,3,   tumCV↓,2,   TumVol↓,1,  
Total Targets: 41

Results for Effect on Normal Cells:

Total Targets: 0

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