Radiotherapy/Radiation / toxicity Cancer Research Results

Rad, Radiotherapy/Radiation: Click to Expand ⟱
Features:
Treatment of disease with radiation, especially by selective irradiation with x-rays or other ionizing radiation and by ingestion of radioisotopes.

Radiosensitizer
Atorvaqone, (mitochondria inhibitor) decrease O2 consumption making more O2 available as a radiosensitizer.
toxicity, toxicity: Click to Expand ⟱
Source:
Type:
Toxicity
Scientific Papers found: Click to Expand⟱
2022- BBR,  GoldNP,  Rad,    Berberine-loaded Janus gold mesoporous silica nanocarriers for chemo/radio/photothermal therapy of liver cancer and radiation-induced injury inhibition
- in-vitro, Liver, SMMC-7721 cell - in-vitro, Nor, HL7702
*toxicity↓, radioP↑, BioAv↑, AntiTum↑, selectivity↑, eff↑, chemoP↑,
5193- dietMet,  Rad,    A Phase I Trial of a Methionine Restricted Diet with Concurrent Radiation Therapy
- Trial, Var, NA
toxicity↝, other↝,
2064- PB,  Rad,    Phenylbutyrate Attenuates the Expression of Bcl-XL, DNA-PK, Caveolin-1, and VEGF in Prostate Cancer Cells
- in-vitro, Pca, PC3 - in-vitro, Pca, DU145 - in-vitro, Pca, LNCaP
Bcl-xL↓, Cav1↓, VEGF↓, RadioS↑, chemoP↑, HDAC↓, *toxicity↓, Diff↑, Prot↓,
5857- RES,  CAP,  Rad,    Resveratrol and capsaicin as safer radiosensitizers for colorectal cancer compared to 5-fluorouracil
- in-vivo, Var, NA
RadioS↑, hepatoP↝, toxicity↓,
4614- SSE,  Rad,    Updates on clinical studies of selenium supplementation in radiotherapy
- Review, Nor, NA
*toxicity∅, Risk↓, *selenoP↑, *ROS↓, *DNAdam↓, *QoL↑, *radioP↑, *Dose↝,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

Cav1↓, 1,  

Cell Death ⓘ

Bcl-xL↓, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,   Prot↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

Diff↑, 1,   HDAC↓, 1,  

Angiogenesis & Vasculature ⓘ

VEGF↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   eff↑, 1,   RadioS↑, 2,   selectivity↑, 1,  

Functional Outcomes ⓘ

AntiTum↑, 1,   chemoP↑, 2,   hepatoP↝, 1,   radioP↑, 1,   Risk↓, 1,   toxicity↓, 1,   toxicity↝, 1,  
Total Targets: 18

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

ROS↓, 1,   selenoP↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Drug Metabolism & Resistance ⓘ

Dose↝, 1,  

Functional Outcomes ⓘ

QoL↑, 1,   radioP↑, 1,   toxicity↓, 2,   toxicity∅, 1,  
Total Targets: 8

Scientific Paper Hit Count for: toxicity, toxicity
5 Radiotherapy/Radiation
1 Berberine
1 Gold NanoParticles
1 diet Methionine-Restricted Diet
1 Phenylbutyrate
1 Resveratrol
1 Capsaicin
1 Selenite (Sodium)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:201  Target#:1025  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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