Radiotherapy/Radiation / Inflam Cancer Research Results

Rad, Radiotherapy/Radiation: Click to Expand ⟱
Features:
Treatment of disease with radiation, especially by selective irradiation with x-rays or other ionizing radiation and by ingestion of radioisotopes.

Radiosensitizer
Atorvaqone, (mitochondria inhibitor) decrease O2 consumption making more O2 available as a radiosensitizer.
Inflam, inflammation: Click to Expand ⟱
Source:
Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.
Scientific Papers found: Click to Expand⟱
3445- ALA,  Rad,    The radioprotective effects of alpha-lipoic acid on radiotherapy-induced toxicities: A systematic review
- Review, Var, NA
*radioP↑, *antiOx↑, *Inflam↓,
4824- ASTX,  Rad,    Astaxanthin protects the radiation-induced lung injury in C57BL/6 female mice
- in-vivo, Nor, NA
*radioP↑, Inflam↓,
1775- MEL,  Chemo,  Rad,    A Systematic Review of the Chemo/Radioprotective Effects of Melatonin against Ototoxic Adverse Effects Induced by Chemotherapy and Radiotherapy
- Review, Var, NA
chemoP↑, radioP↑, antiOx↑, Inflam↑,
3015- RosA,  Rad,    Rosmarinic Acid Prevents Radiation-Induced Pulmonary Fibrosis Through Attenuation of ROS/MYPT1/TGFβ1 Signaling Via miR-19b-3p
- in-vivo, Nor, IMR90
*radioP↑, *Inflam↓, *ROS↓, *NF-kB↓, *Rho↓, *ROCK1↓, *other↓,
3012- RosA,  Rad,    Rosmarinic Acid Prevents Radiation-Induced Pulmonary Fibrosis Through Attenuation of ROSMYPT1TGFβ1 Signaling Via miR-19b-3p
- in-vitro, Nor, IMR90
*Inflam↓, *ROS↓, *p‑NF-kB↓, *Rho↓, *ROCK1↓, *radioP↑, *MCP1↓, *RANTES↓, *ICAM-1↓, *PGC1A↑, *NOX4↓, *Dose↝,
4612- SeNPs,  Rad,    Histopathological Evaluation of Radioprotective Effects: Selenium Nanoparticles Protect Lung Tissue from Radiation Damage
- in-vivo, Nor, NA
*radioP↑, *Inflam↓, *antiOx↑, *Dose↝, *DNAdam↓, *ROS↓, *SOD↑, *GPx↑, *Dose↝, *eff↑,
4611- SeNPs,  Rad,    Radioprotective Effect of Selenium Nanoparticles: A Mini Review
- Review, Var, NA
*antiOx↑, *Inflam↓, *radioP↑, *ROCK1↓, *DNAdam↓, *Apoptosis↓, *RadioS↑, *Dose↝,
3306- SIL,  Rad,    Radioprotective and radiosensitizing properties of silymarin/silibinin in response to ionizing radiation
- Review, Var, NA
radioP↑, RadioS↑, TumCMig↓, TumCI↓, angioG↓, Apoptosis↑, DNAdam↓, ROS↑, *ROS↓, *Inflam↓,
4610- SSE,  Rad,    Protection during radiotherapy: selenium
- Review, Var, NA
*radioP↑, *antiOx↑, *Inflam↓, *DNAdam↓, *lipid-P↓, *selenoP↑, *GPx1↑, *BUN↓,
4739- SSE,  Chemo,  Rad,    Therapeutic Benefits of Selenium in Hematological Malignancies
- Review, Var, NA
ChemoSen↑, radioP↑, QoL↑, Risk↓, *selenoP↑, TumCP↓, Inflam↓, ChemoSen↑, TumCCA↑, Apoptosis↑, angioG↓, Dose⇅, ROS↑, eff↑, Risk↓, eff∅, CSCs↓, ROS↑,

Showing Research Papers: 1 to 10 of 10

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 10

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   ROS↑, 3,  

Cell Death ⓘ

Apoptosis↑, 2,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

CSCs↓, 1,  

Migration ⓘ

TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 2,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 2,   Inflam↑, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 2,   Dose⇅, 1,   eff↑, 1,   eff∅, 1,   RadioS↑, 1,  

Functional Outcomes ⓘ

chemoP↑, 1,   QoL↑, 1,   radioP↑, 3,   Risk↓, 2,  
Total Targets: 21

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 4,   GPx↑, 1,   GPx1↑, 1,   lipid-P↓, 1,   NOX4↓, 1,   ROS↓, 4,   selenoP↑, 2,   SOD↑, 1,  

Core Metabolism/Glycolysis ⓘ

BUN↓, 1,   PGC1A↑, 1,  

Cell Death ⓘ

Apoptosis↓, 1,  

Transcription & Epigenetics ⓘ

other↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 3,  

Migration ⓘ

Rho↓, 2,   ROCK1↓, 3,  

Immune & Inflammatory Signaling ⓘ

ICAM-1↓, 1,   Inflam↓, 7,   MCP1↓, 1,   NF-kB↓, 1,   p‑NF-kB↓, 1,   RANTES↓, 1,  

Drug Metabolism & Resistance ⓘ

Dose↝, 4,   eff↑, 1,   RadioS↑, 1,  

Functional Outcomes ⓘ

radioP↑, 7,  
Total Targets: 25

Scientific Paper Hit Count for: Inflam, inflammation
10 Radiotherapy/Radiation
2 Chemotherapy
2 Rosmarinic acid
2 Selenium NanoParticles
2 Selenite (Sodium)
1 Alpha-Lipoic-Acid
1 Astaxanthin
1 Melatonin
1 Silymarin (Milk Thistle) silibinin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:201  Target#:953  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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