| Features: |
| Treatment of disease with radiation, especially by selective irradiation with x-rays or other ionizing radiation and by ingestion of radioisotopes. Radiosensitizer Atorvaqone, (mitochondria inhibitor) decrease O2 consumption making more O2 available as a radiosensitizer. |
| 1337- | 2DG, | Rad, | 2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer |
| - | in-vivo, | NA, | NA |
| 5279- | 3BP, | Rad, | Abstract 5243: 3-Bromopyruvate in combination with radiation inhibits pancreatic cancer growth by dismantling mitochondria and ATP generation in a preclinical mouse model |
| - | in-vivo, | PC, | NA |
| 5282- | 3BP, | Rad, | 3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-468 |
| 328- | AgNPs, | Rad, | Silver nanoparticles outperform gold nanoparticles in radiosensitizing U251 cells in vitro and in an intracranial mouse model of glioma |
| - | vitro+vivo, | GBM, | U251 |
| 4358- | AgNPs, | HPT, | Rad, | Silver nanocrystals mediated combination therapy of radiation with magnetic hyperthermia on glioma cells |
| - | in-vitro, | GBM, | U251 |
| 4400- | AgNPs, | Rad, | Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | Nor, | MCF10 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | BT549 | - | in-vivo, | BC, | MDA-MB-231 |
| 4401- | AgNPs, | Rad, | Metformin-loaded chitosan nanoparticles augment silver nanoparticle-induced radiosensitization in breast cancer cells during radiation therapy |
| - | in-vitro, | BC, | NA |
| 4404- | AgNPs, | Rad, | Main Approaches to Enhance Radiosensitization in Cancer Cells by Nanoparticles: A Systematic Review |
| - | Review, | Var, | NA |
| 4563- | AgNPs, | Rad, | Silver nanoparticles enhance neutron radiation sensitivity in cancer cells: An in vitro study |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | Ovarian, | SKOV3 | - | in-vitro, | GBM, | U87MG | - | in-vitro, | Melanoma, | A431 |
| 329- | AgNPs, | Rad, | Enhancement of radiotherapy efficacy by silver nanoparticles in hypoxic glioma cells |
| - | in-vitro, | GBM, | U251 |
| 330- | AgNPs, | Rad, | Reactive oxygen species acts as executor in radiation enhancement and autophagy inducing by AgNPs |
| - | in-vitro, | GBM, | U251 |
| 331- | AgNPs, | Rad, | Silver nanoparticles: a novel radiation sensitizer for glioma? |
| - | vitro+vivo, | GBM, | NA |
| 332- | AgNPs, | Rad, | Enhancement of Radiosensitization by Silver Nanoparticles Functionalized with Polyethylene Glycol and Aptamer As1411 for Glioma Irradiation Therapy |
| - | in-vivo, | GBM, | NA |
| 2669- | AL, | Rad, | Inhibition of ICAM-1 expression by garlic component, allicin, in gamma-irradiated human vascular endothelial cells via downregulation of the JNK signaling pathway |
| - | in-vitro, | Nor, | HUVECs |
| 2668- | AL, | Rad, | Allicin enhances the radiosensitivity of colorectal cancer cells via inhibition of NF-κB signaling pathway |
| - | in-vitro, | CRC, | HCT116 |
| 3445- | ALA, | Rad, | The radioprotective effects of alpha-lipoic acid on radiotherapy-induced toxicities: A systematic review |
| - | Review, | Var, | NA |
| 298- | ALA, | Rad, | Synergistic Tumoricidal Effects of Alpha-Lipoic Acid and Radiotherapy on Human Breast Cancer Cells via HMGB1 |
| - | in-vitro, | BC, | MDA-MB-231 |
| 2583- | Api, | Rad, | The influence of apigenin on cellular responses to radiation: From protection to sensitization |
| - | Review, | Var, | NA |
| 3163- | Ash, | Rad, | Withaferin A, a steroidal lactone, selectively protects normal lymphocytes against ionizing radiation induced apoptosis and genotoxicity via activation of ERK/Nrf-2/HO-1 axis |
| 4822- | ASTX, | Rad, | Astaxanthin Synergizes with Ionizing Radiation (IR) in Oral Squamous Cell Carcinoma (OSCC) |
| 4824- | ASTX, | Rad, | Astaxanthin protects the radiation-induced lung injury in C57BL/6 female mice |
| - | in-vivo, | Nor, | NA |
| 4979- | ATV, | Rad, | Short‐Term Statin Treatment Reduces, and Long‐Term Statin Treatment Abolishes, Chronic Vascular Injury by Radiation Therapy |
| - | in-vivo, | Nor, | NA |
| 4978- | ATV, | Rad, | Atorvastatin Sensitizes Breast and Lung Cancer Cells to Ionizing Radiation |
| - | in-vitro, | BC, | A549 |
| 5367- | AV, | Rad, | Aloe vera for prevention of radiation-induced dermatitis: a self-controlled clinical trial |
| - | Trial, | Var, | NA |
| 2622- | Ba, | Cisplatin, | Rad, | Natural Baicalein-Rich Fraction as Radiosensitizer in Combination with Bismuth Oxide Nanoparticles and Cisplatin for Clinical Radiotherapy |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MCF-7 |
| 2481- | Ba, | Rad, | Radiotherapy Increases 12-LOX and CCL5 Levels in Esophageal Cancer Cells and Promotes Cancer Metastasis via THP-1-Derived Macrophages |
| - | in-vitro, | ESCC, | Eca109 | - | in-vitro, | ESCC, | KYSE150 |
| 2289- | Ba, | Rad, | Baicalein Inhibits the Progression and Promotes Radiosensitivity of Esophageal Squamous Cell Carcinoma by Targeting HIF-1A |
| - | in-vitro, | ESCC, | KYSE150 |
| 2769- | Ba, | Rad, | Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis |
| - | in-vivo, | Nor, | NA |
| 1399- | BBR, | Rad, | Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review |
| - | Review, | NA, | NA |
| 2715- | BBR, | Rad, | Berberine Can Amplify Cytotoxic Effect of Radiotherapy by Targeting Cancer Stem Cells |
| - | in-vitro, | BC, | MCF-7 |
| 1381- | BBR, | Rad, | Berberine enhances the sensitivity of radiotherapy in ovarian cancer cell line (SKOV-3) |
| - | in-vitro, | Ovarian, | SKOV3 |
| 1390- | BBR, | Rad, | Berberine Inhibited Radioresistant Effects and Enhanced Anti-Tumor Effects in the Irradiated-Human Prostate Cancer Cells |
| - | in-vitro, | Pca, | PC3 |
| 2022- | BBR, | GoldNP, | Rad, | Berberine-loaded Janus gold mesoporous silica nanocarriers for chemo/radio/photothermal therapy of liver cancer and radiation-induced injury inhibition |
| - | in-vitro, | Liver, | SMMC-7721 cell | - | in-vitro, | Nor, | HL7702 |
| 5587- | BetA, | Rad, | Effects of betulinic acid alone and in combination with irradiation in human melanoma cells |
| - | in-vitro, | Melanoma, | NA |
| 5662- | BNL, | Rad, | Role of Borneol Induced Autophagy in Enhancing Radiosensitivity of Malignant Glioma |
| - | vitro+vivo, | GBM, | NA |
| 702- | Bor, | GEN, | SeMet, | Rad, | Evaluation of ecological and in vitro effects of boron on prostate cancer risk (United States) |
| - | Analysis, | NA, | NA |
| 5741- | Buty, | Rad, | Microencapsulated Sodium Butyrate in the Prevention of Acute Radiotherapy Proctitis: Single-Center Prospective Study |
| - | in-vivo, | Pca, | NA |
| 5749- | CA, | Z, | Rad, | Antitumor and Radiosensitizing Effects of Zinc Oxide-Caffeic Acid Nanoparticles against Solid Ehrlich Carcinoma in Female Mice |
| - | vitro+vivo, | BC, | MCF-7 | - | NA, | Liver, | HepG2 |
| 5754- | CAPE, | Rad, | The radiosensitizing effect of Caffeic Acid Phenethyl Ester in breast cancer is dependent on p53 status |
| - | in-vivo, | BC, | MDA-MB-231 |
| 5863- | carbop, | Rad, | Carboplatin as a potentiator of radiation therapy |
| - | vitro+vivo, | Lung, | NA |
| 5972- | CET, | Rad, | Retrospective Trial on Cetuximab Plus Radiotherapy in Elderly Patients with Head and Neck Squamous Cell Cancer |
| - | Trial, | HNSCC, | NA |
| 6005- | CGA, | Rad, | Chlorogenic Acid, the Main Antioxidant in Coffee, Reduces Radiation-Induced Apoptosis and DNA Damage via NF-E2-Related Factor 2 (Nrf2) Activation in Hepatocellular Carcinoma |
| - | in-vitro, | HCC, | HUH7 |
| 2804- | CHr, | Rad, | Gamma-Irradiated Chrysin Improves Anticancer Activity in HT-29 Colon Cancer Cells Through Mitochondria-Related Pathway |
| - | in-vitro, | CRC, | HT29 |
| 1980- | CUR, | Rad, | Thioredoxin reductase-1 (TxnRd1) mediates curcumin-induced radiosensitization of squamous carcinoma cells |
| - | in-vitro, | Cerv, | HeLa | - | in-vitro, | Laryn, | FaDu |
| 1485- | CUR, | Chemo, | Rad, | Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs |
| - | Review, | Var, | NA |
| 1979- | CUR, | Rad, | Dimethoxycurcumin, a metabolically stable analogue of curcumin enhances the radiosensitivity of cancer cells: Possible involvement of ROS and thioredoxin reductase |
| - | in-vitro, | Lung, | A549 |
| 5195- | DCA, | Rad, | Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells |
| - | in-vitro, | BC, | 4T1 | - | in-vitro, | BC, | EMT6 |
| 1870- | DCA, | Rad, | Dichloroacetate (DCA) sensitizes both wild-type and over expressing Bcl-2 prostate cancer cells in vitro to radiation |
| - | in-vitro, | Pca, | PC3 |
| 5193- | dietMet, | Rad, | A Phase I Trial of a Methionine Restricted Diet with Concurrent Radiation Therapy |
| - | Trial, | Var, | NA |
| 5010- | DSF, | Cu, | Rad, | Disulfiram/Copper Combined with Irradiation Induces Immunogenic Cell Death in Melanoma |
| - | in-vivo, | Melanoma, | B16-F10 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:201 Target#:% State#:% Dir#:%
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