probiotics Cancer Research Results

ProBio, probiotics: Click to Expand ⟱
Features:
Probiotics contain live bacteria the supplements the gastrointestinal flora. (Which can be affected from infection or antibiotics drugs.)
Some studies have suggested that gut microbiota—including Bifidobacterium species—can affect systemic immunity. This is important because the state of the immune system influences the body’s ability to fight cancer and also the response to immunotherapies.
Preclinical investigations have demonstrated that certain Bifidobacterium strains may help improve responses to immune checkpoint inhibitors in animal models.
There has been emerging research looking into discrete strains or formulations of Bifidobacterium longum (sometimes labeled with additional identifiers such as RAPO) that may have unique properties or enhanced effects.


Scientific Papers found: Click to Expand⟱
4599- AgNPs,  ProBio,    Impacts of dietary silver nanoparticles and probiotic administration on the microbiota of an in-vitro gut model
- in-vivo, Nor, NA
*GutMicro∅, *chemoPv↑,
5629- Bif,  ProBio,    Gut microbiota shapes cancer immunotherapy responses
- Review, Var, NA
eff↑, DCells↑, CD8+↑, eff↑, AntiTum↑, other↑, selectivity↑, GutMicro↑,
1046- ProBio,  immuno,    Combination Therapy of Bifidobacterium longum RAPO With Anti-PD-1 Treatment Enhances Anti-tumor Immune Response in Association With Gut Microbiota Modulation
- in-vivo, NA, NA
TumVol↓, GutMicro↑,
4170- ProBio,  PB,    Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-d-aspartate receptor subunits and d-serine
- in-vivo, NA, NA
*BDNF↑, *GutMicro↑,
4866- ProBio,    Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis
- in-vivo, AD, NA
*memory↑, *other↝, *GutMicro↝, *GutMicro↝, *GutMicro↝,
5624- ProBio,  Bif,    A randomized double-blind placebo-controlled trial of probiotics in post-surgical colorectal cancer
- Trial, Testi, NA
Dose↝, TNF-α↓, IL6↓, IL10↓, IL12↓, IL22↓, toxicity↓,
5630- ProBio,  Bif,    EFFICACY OF PROBIOTICS IN PREVENTING CHEMOTHERAPY-INDUCED DIARRHEA IN GASTROINTESTINAL CANCER PATIENTS
- Trial, GC, NA
Dose↝, Diar⇅,
4090- VitK2,  ProBio,    Vitamin K2 Holds Promise for Alzheimer's Prevention and Treatment
- Review, AD, NA
*antiOx↑, *Inflam↓, *Aβ↓, *memory↑, *NF-kB↓, *ROS↓, *GSH↑, *ATP↑, *p‑tau↓, *cardioP↑, *other↝, *cognitive↑,

Showing Research Papers: 1 to 8 of 8

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned

Diar⇅, 1,  

Transcription & Epigenetics

other↑, 1,  

Immune & Inflammatory Signaling

DCells↑, 1,   IL10↓, 1,   IL12↓, 1,   IL22↓, 1,   IL6↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance

Dose↝, 2,   eff↑, 2,   selectivity↑, 1,  

Clinical Biomarkers

GutMicro↑, 2,   IL6↓, 1,  

Functional Outcomes

AntiTum↑, 1,   toxicity↓, 1,   TumVol↓, 1,  

Infection & Microbiome

CD8+↑, 1,  
Total Targets: 17

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,   GSH↑, 1,   ROS↓, 1,  

Mitochondria & Bioenergetics

ATP↑, 1,  

Transcription & Epigenetics

other↝, 2,  

Immune & Inflammatory Signaling

Inflam↓, 1,   NF-kB↓, 1,  

Synaptic & Neurotransmission

BDNF↑, 1,   p‑tau↓, 1,  

Protein Aggregation

Aβ↓, 1,  

Clinical Biomarkers

GutMicro↑, 1,   GutMicro↝, 3,   GutMicro∅, 1,  

Functional Outcomes

cardioP↑, 1,   chemoPv↑, 1,   cognitive↑, 1,   memory↑, 2,  
Total Targets: 17

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:256  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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