Database Query Results : Sulfasalazine, ,

Sulfas, Sulfasalazine: Click to Expand ⟱
Features:
Sulfasalazine is primarily known as an anti-inflammatory and disease‐modifying antirheumatic drug (DMARD), used for conditions such as rheumatoid arthritis and inflammatory bowel diseases (e.g., ulcerative colitis).

-Inhibit the nuclear factor kappa B (NF-κB) pathway.
-Sulfasalazine has been noted to interfere with the cystine/glutamate antiporter (system x_c⁻), which can reduce glutathione levels in cancer cells, potentially making them more susceptible to oxidative stress.

-Ability to inhibit anti-oxidant production (for ProOxidant effect).
Scientific Papers found: Click to Expand⟱
3853- Sulfas,    Sulfur-containing therapeutics in the treatment of Alzheimer's disease
- Review, AD, NA
*antiOx↑, A lot of research has been conducted on sulfur-containing compounds in the context of AD due to their innate antioxidant potential


* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Results for Effect on Cancer/Diseased Cells:

Total Targets: 0

Results for Effect on Normal Cells:
antiOx↑,1,  
Total Targets: 1

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:286  Target#:%  State#:%  Dir#:%
  wNotes=on  sortOrder:rid,rpid

 

Home Page