dietP, diet Plant based: Click to Expand ⟱
Features:
A diet high in whole grains, vegetables, and fruits and low in red/processed meats, and low alcohol.

-Some studies indicate high fruit consumption (but not orange juice) may be associated with poorer survival.
-Vegetable consumption, particularly green leafy and cruciferous vegetables, was associated with better overall survival.

-If juice has higher sugar level (from fruits) they can affect blood glucose levels.
-If juice have high oxalate content they can be hard on kidneys.
-If juices have high vitamin K content they can affect blood thinners.
Scientific Papers found: Click to Expand⟱
2154- dietP,  Ex,    American Cancer Society (ACS) Nutrition and Physical Activity Guidelines after colon cancer diagnosis and disease-free (DFS), recurrence-free (RFS), and overall survival (OS) in CALGB 89803 (Alliance)
- Trial, Colon, NA
OS↑, Colon cancer patients with a healthy body weight who engaged in physical activity, ate a diet high in whole grains, vegetables, and fruits and low in red/processed meats, and drank moderate alcohol had longer DFS and OS than patients who did not

2155- dietP,    Transepithelial Anti-Neuroblastoma Response to Kale among Four Vegetable Juices Using In Vitro Model Co-Culture System
- in-vivo, neuroblastoma, Caco-2 - NA, NA, SH-SY5Y
AntiCan↑, Juicing vegetables is thought to be an anticancer treatment. Support exists for a rank order of anticancer greens (kale > dandelion > lettuce > spinach) based on degrees of bioavailability of different phytochemicals
ROS↑, Kale juice uniquely induced reactive oxygen species and S-phase cell cycle arrest in SH-SY5Y. no differentiation agents were added to SH-SY5Ys, leaving them fully metastatic
eff↑, Fermentation enhances some
eff↑, By and large, most phytochemicals are best prepared for human consumption by fresh juicing
eff↑, kale’s abundant and diverse phytochemical flavonoids (Scheme 1B), also found in other Brassica such as cauliflower, broccoli, Brussel sprouts, and cabbages

2156- dietP,    Phytochemical-rich vegetable and fruit juice alleviates oral mucositis during concurrent chemoradiotherapy in patients with locally advanced head and neck cancer
- Human, HNSCC, NA
chemoP↑, In head and neck cancer patients, the VFJ was significantly associated with a lower risk of chemoradiotherapy-induced ulcerative oral mucositis.
radioP↑,
eff↑, incidence of ulcerative OM was significantly lower in VFJ (64.0%) than in control (95.8%) subjects at week 6 of CCRT.

2157- dietP,    Plant-Based Diets and Disease Progression in Men With Prostate Cancer
- Study, Pca, NA
TumCG↓, individuals with the highest intake of plant foods in the overall plant-based diet index had lower risk of prostate cancer progression compared with those with the lowest intake.
Risk↓, 47% lower risk of progression
eff↑, 1.9 additional servings of vegetables, 1.6 additional servings of fruit, 0.9 more servings of whole grains, 1.0 less serving of dairy, 0.4 less servings of animal fat, slightly less egg, and marginally less meat

2158- dietP,    Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality in a Japanese Cohort
- Human, Nor, NA
OS↓, In this cohort study of 70 696 Japanese adults followed up for a mean of 18 years, higher intake of plant protein was associated with lower total mortality.
Risk↓, substitution of plant protein for animal protein, mainly for red or processed meat protein, was associated with lower risk of total, cancer-related, and cardiovascular disease–related mortality.

2159- dietP,    Postdiagnostic Fruit and Vegetable Consumption and Breast Cancer Survival: Prospective Analyses in the Nurses' Health Studies
- Human, BC, NA
Risk↑, Apple juice largely accounted for these higher risks
Risk∅, and orange juice was not associated with risk
OS↑, higher vegetable consumption, particularly green leafy and cruciferous vegetables, was associated with better overall survival among patients with breast cancer.
OS↓, Higher fruit juice consumption, but not orange juice, was associated with poorer breast cancer–specific and all-cause survival.

2160- dietP,    Dietary proteins and protein sources and risk of death: the Kuopio Ischaemic Heart Disease Risk Factor Study
- Trial, Heart, NA
Risk↓, Higher ratio of animal to plant protein in diet and higher meat intake were associated with increased mortality risk. (meaning higher plant ratio is lower risk)

2161- dietP,    Plant-Based Diets and Cancer Prognosis: a Review of Recent Research
- Review, NA, NA
OS↑, higher intake of plant-based foods was associated with improved prognosis in cancer survivors
eff↑, colorectal cancer survival, a better prognosis was observed for a high intake of whole grains and fibre
eff↑, For breast cancer survival, a higher intake of fruit, vegetable and fibre and a moderate intake of soy/isoflavone were associated with beneficial outcomes

2162- dietP,    Effect of low-fat diet on breast cancer survival: a meta-analysis
- Analysis, BC, NA
Risk↓, Post-diagnostic low-fat diet reduced risk of recurrence of breast cancer by 23%
OS↑, and all cause mortality of breast cancer by 17%

2163- dietP,  SFN,    Intake of Cruciferous Vegetables Modifies Bladder Cancer Survival
- Human, Bladder, NA
OS↑, a strong and significant inverse association was observed between bladder cancer mortality and broccoli intake
OS∅, There were no significant associations for total vegetables, total fruits, or other individual cruciferous vegetables.

2165- dietP,  SFN,    Broccoli sprout supplementation in patients with advanced pancreatic cancer is difficult despite positive effects—results from the POUDER pilot study
- Trial, PC, NA
Dose↝, Fifteen capsules with pulverized broccoli sprouts containing 90 mg/508 μmol sulforaphane and 180 mg/411 μmol glucoraphanin or methylcellulose were administered daily for up to 1 year.
OS↑, Compared to those of the placebo group, the mean death rate was lower in the treatment group during the first 6 months after intake
eff↝, broccoli sprouts sometimes increased digestive problems, nausea and emesis.

2164- SFN,  dietP,    Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice
- in-vitro, Pca, NA
HDAC↓, broccoli sprouts, inhibits epigenetic regulators such as histone deacetylase (HDAC) enzymes. significant decline in HDAC3 protein expression in the epithelial cells of prostate ventral
Dose↝, TRAMP mice were fed a 15% broccoli sprout
Risk↓, Broccoli sprouts reduced prostate cancer incidence and progression to invasive cancer by 11- and 2.4-fold at 12 and 28 wk of age, respectively.
TumCP↓,
H3↓, Broccoli sprout consumption also decreased histone H3 lysine 9 trimethylation in the ventral lobe (age 12 wk), and decreased histone H3 lysine 18 acetylation in all prostate lobes (age 28 wk).


* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 12

Results for Effect on Cancer/Diseased Cells:
AntiCan↑,1,   chemoP↑,1,   Dose↝,2,   eff↑,7,   eff↝,1,   H3↓,1,   HDAC↓,1,   OS↓,2,   OS↑,6,   OS∅,1,   radioP↑,1,   Risk↓,5,   Risk↑,1,   Risk∅,1,   ROS↑,1,   TumCG↓,1,   TumCP↓,1,  
Total Targets: 17

Results for Effect on Normal Cells:

Total Targets: 0

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:308  Target#:%  State#:%  Dir#:%
  wNotes=on  sortOrder:rid,rpid

 

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