Glucose Cancer Research Results
Gluc, Glucose: Click to Expand ⟱
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Glucose is a fundamental energy source and its metabolism is essential for all cells, the reprogramming of glucose metabolism in cancer cells underlies many aspects of tumor growth and survival.
-Glucose generally aids cancer cells, but can be used as trojan horse.
-HIF-1 increases the expression of glycolytic enzymes
-Hexokinase II, which catalyzes the first step of glycolysis (often upregulated).
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Scientific Papers found: Click to Expand⟱
Dose?,
Dose↝, eff↑, ROS↑, eff↝, eff↑, eff↝, eff↑, eff↝,
eff↝, TumCCA↑, eff↑, eff↑, ROS↑, GSH↓, SOD↓, lipid-P↑, LDH↑,
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in-vitro, |
Pca, |
PC3 |
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in-vitro, |
Pca, |
LNCaP |
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in-vitro, |
Pca, |
DU145 |
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selectivity↑, ROS↑, mtDam↑, TumCCA↑, TumCP↓, Apoptosis↑, MMP↓,
Showing Research Papers: 1 to 4 of 4
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
GSH↓, 1, lipid-P↑, 1, ROS↑, 3, SOD↓, 1,
Mitochondria & Bioenergetics ⓘ
MMP↓, 1, mtDam↑, 1,
Core Metabolism/Glycolysis ⓘ
LDH↑, 1,
Cell Death ⓘ
Apoptosis↑, 1,
Cell Cycle & Senescence ⓘ
TumCCA↑, 2,
Migration ⓘ
TumCP↓, 1,
Drug Metabolism & Resistance ⓘ
Dose?, 1, Dose↝, 1, eff↑, 5, eff↝, 4, selectivity↑, 1,
Clinical Biomarkers ⓘ
LDH↑, 1,
Total Targets: 16
Pathway results for Effect on Normal Cells:
Total Targets: 0
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:335 Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid
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