Database Query Results : Salvia officinalis, ,

Sage, Salvia officinalis: Click to Expand ⟱
Features:
Salvia officinalis(common sage) has been studied for its potential therapeutic effects in Alzheimer's disease (AD) and cancer due to its antioxidant, anti-inflammatory, neuroprotective, and anticancer properties.
-Sage contains compounds (e.g., rosmarinic acid, luteolin, carnosic acid) that inhibit acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).This enhances acetylcholine levels, supporting memory and cognition — similar to drugs like donepezil.
-High in phenolic compounds (e.g., flavonoids, diterpenes) that scavenge reactive oxygen species (ROS).

-High doses of thujone (a compound in some sage oils) may be neurotoxic or hepatotoxic.
Scientific Papers found: Click to Expand⟱
3757- RosA,  Sage,  Croc,  NarG,  Caff  Food-derived Acetylcholinesterase Inhibitors as Potential Agents against Alzheimer’s Disease
- Review, AD, NA
AChE↓,
3638- Sage,    Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial
- Trial, AD, NA
*cognitive↑,
3639- Sage,    Pharmacological properties of Salvia officinalis and its components
- Review, AD, NA - Review, Var, NA
AntiCan↑, *Inflam↓, *antiOx↑, *cognitive↑, *memory↑, *LDL↓, TumCG↓, MAPK↓, ROS↓, NF-kB↓, COX2↓, angioG↓, *AST↓, *ALAT?,
3640- Sage,    Evaluation of Traditional Herb Extract Salvia officinalis in Treatment of Alzheimers Disease
- in-vivo, AD, NA
*antiOx↑, *memory↑,
3641- Sage,    Systematic Review of Clinical Trials Assessing Pharmacological Properties of Salvia Species on Memory, Cognitive Impairment and Alzheimer's Disease
- Review, AD, NA
*cognitive↑, *memory↑, *AChE↓,
3642- Sage,    Chronic Supplementation with a Mix of Salvia officinalis and Salvia lavandulaefolia Improves Morris Water Maze Learning in Normal Adult C57Bl/6J Mice
- in-vivo, AD, NA
*memory↑, *cognitive↑,
3643- Sage,    Effects of cholinesterase inhibiting sage (Salvia officinalis) on mood, anxiety and performance on a psychological stressor battery
- Human, Nor, NA
*cognitive↑, *AChE↓,
3644- Sage,    Positive modulation of mood and cognitive performance following administration of acute doses of Salvia lavandulaefolia essential oil to healthy young volunteers
- Human, AD, NA
*memory↑, *cognitive↑,
3645- Sage,  RosA,    Acetylcholinesterase inhibitory, antioxidant and phytochemical properties of selected medicinal plants of the Lamiaceae family
- Study, AD, NA
*AChE↓, *AChE↓,
4217- Sage,  RosA,  Aroma,    Neuroprotective Potential of Aromatic Herbs: Rosemary, Sage, and Lavender
- Review, AD, NA - Review, Park, NA
*Inflam↓, *antiOx↑, *neuroP↑, *ERK↑, *CREB↑, *BDNF↑, *Aβ↑, *AChE↓, *memory↑, *cognitive↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 10

Results for Effect on Normal Cells:
AChE↓,5,   ALAT?,1,   antiOx↑,3,   AST↓,1,   Aβ↑,1,   BDNF↑,1,   cognitive↑,7,   CREB↑,1,   ERK↑,1,   Inflam↓,2,   LDL↓,1,   memory↑,6,   neuroP↑,1,  
Total Targets: 13

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:338  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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