Zeaxanthin / MPOD Cancer Research Results

Zeax, Zeaxanthin: Click to Expand ⟱
Features:
Zeaxanthin
-Orange peppers, corn, egg yolks, Paprika
-Antioxidant properties reduce lipid peroxidation
-Inhibits cancer cell proliferation in vitro
-Protects against UV-induced DNA damage
-reduced risk of prostate cancer
MPOD, Macular Pigment Optical Density: Click to Expand ⟱
Source:
Type:
MPOD is a measure of the concentration of macular pigments—primarily lutein, zeaxanthin, and meso-zeaxanthin—in the central retina (macula). These pigments are potent antioxidants and blue-light filters, and they help protect retinal and neural tissue from oxidative damage.
-MPOD is often reduced in AD patients
-MPOD can be measured non-invasively (with heterochromatic flicker photometry or similar tools), it may help in early identification of individuals at risk of cognitive decline.
Scientific Papers found: Click to Expand⟱
4192- Lut,  Zeax,    Lutein and Zeaxanthin Supplementation Improves Dynamic Visual and Cognitive Performance in Children: A Randomized, Double-Blind, Parallel, Placebo-Controlled Study
- Trial, NA, NA
*MPOD↑, LZ group showed significant increases in MPOD at all visits post-supplementation, with significant increases as early as day 42 compared to placebo
*cognitive↑, LZ group showed significant increases in serum lutein levels, reduced eye strain and fatigue, and improved cognitive performance (focus, episodic memory and learning, visuospatial working memory) at days 90 and 180 compared to placebo.
*memory↑,
*BDNF↑, LZ group showed significant increases in processing speed (CFF), attention, visuospatial processing, and serum Z and BDNF levels on day 180 compared to placebo.

4193- Lut,  Zeax,    Effects of a Lutein and Zeaxanthin Intervention on Cognitive Function: A Randomized, Double-Masked, Placebo-Controlled Trial of Younger Healthy Adults
- Trial, NA, NA
*MPOD↑, Supplementation increased MPOD significantly over the course of the year,
*cognitive↑, Supplementation with L + Z improves CNS xanthophyll levels and cognitive function in young, healthy adults
*memory↑, improvement in spatial memory following one-year supplementation

4194- Lut,  Zeax,    Effect of macular pigment carotenoids on cognitive functions: A systematic review
- Review, NA, NA
*MPOD↑, Dietary lutein and zeaxanthin intake increased MPOD in six of the seven clinical trials and significantly improved most of the cognitive functions studied.
*cognitive↑,
*memory↑, Memory, processing speed, attention and reasoning were the cognitive function significantly related to MPOD levels in adults.


Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

MPOD↑, 3,  

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,  

Functional Outcomes ⓘ

cognitive↑, 3,   memory↑, 3,  
Total Targets: 4

Scientific Paper Hit Count for: MPOD, Macular Pigment Optical Density
3 Lutein
3 Zeaxanthin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:348  Target#:1373  State#:%  Dir#:%
  wNotes=on  sortOrder:rid,rpid

 

Home Page