Zeaxanthin / memory Cancer Research Results

Zeax, Zeaxanthin: Click to Expand ⟱
Features:
Zeaxanthin
-Orange peppers, corn, egg yolks, Paprika
-Antioxidant properties reduce lipid peroxidation
-Inhibits cancer cell proliferation in vitro
-Protects against UV-induced DNA damage
-reduced risk of prostate cancer
memory, memory: Click to Expand ⟱
Source:
Type:
Memory
Scientific Papers found: Click to Expand⟱
3980- Lut,  Zeax,    Supplementation With Carotenoids, Omega-3 Fatty Acids, and Vitamin E Has a Positive Effect on the Symptoms and Progression of Alzheimer's Disease
- Trial, AD, NA
*eff↑, emonstrated statistically significant improvements in skin carotenoid measurements, blood carotenoids, ω-3FAs, and vitamin E concentrations (p < 0.05, for all).
*memory↑, active group also performed better in objective measures of AD severity (i.e., memory and mood), with a statistically significant difference reported in the clinical collateral for memory
*Mood↑,
*QoL↑, Exponential increases in the prevalence of AD and its relentless progressive nature is driving the need for interventions that help to ameliorate symptoms and improve quality of life in AD patients.

3981- Lut,  Zeax,  VitE,    Omega-3 fatty acid, carotenoid and vitamin E supplementation improves working memory in older adults: A randomised clinical trial
- Trial, AD, NA
*memory↑, Following 24-month supplementation, individuals in the active group (n = 30; aged 69.03 ± 4.41 years; 56.7% female) recorded significantly fewer errors in working memory tasks than individuals receiving placebo
*other↑, Statistically significant improvements in tissue carotenoid concentrations, serum xanthophyll carotenoid concentrations and plasma ω-3FA concentrations were also observed in the active group versus placebo
*cognitive↑, Increasing nutritional intake of carotenoids and ω-3FAs may prove beneficial in reducing cognitive decline and dementia risk in later life.

3982- Lut,  Zeax,    Nutritional Intervention to Prevent Alzheimer's Disease: Potential Benefits of Xanthophyll Carotenoids and Omega-3 Fatty Acids Combined
- Trial, AD, NA
*memory↑, Xanthophyll carotenoid concentration increases were significantly greater for Formulation 2 compared to Formulation 1 (p < 0.05), and progression of AD was less for this group (p = 0.003), with carers reporting functional benefits in memory, sight, a
*eff↑, positive outcomes for patients with AD who consumed a combination of xanthophyll carotenoids plus fish oil
*Mood↑,

4192- Lut,  Zeax,    Lutein and Zeaxanthin Supplementation Improves Dynamic Visual and Cognitive Performance in Children: A Randomized, Double-Blind, Parallel, Placebo-Controlled Study
- Trial, NA, NA
*MPOD↑, LZ group showed significant increases in MPOD at all visits post-supplementation, with significant increases as early as day 42 compared to placebo
*cognitive↑, LZ group showed significant increases in serum lutein levels, reduced eye strain and fatigue, and improved cognitive performance (focus, episodic memory and learning, visuospatial working memory) at days 90 and 180 compared to placebo.
*memory↑,
*BDNF↑, LZ group showed significant increases in processing speed (CFF), attention, visuospatial processing, and serum Z and BDNF levels on day 180 compared to placebo.

4193- Lut,  Zeax,    Effects of a Lutein and Zeaxanthin Intervention on Cognitive Function: A Randomized, Double-Masked, Placebo-Controlled Trial of Younger Healthy Adults
- Trial, NA, NA
*MPOD↑, Supplementation increased MPOD significantly over the course of the year,
*cognitive↑, Supplementation with L + Z improves CNS xanthophyll levels and cognitive function in young, healthy adults
*memory↑, improvement in spatial memory following one-year supplementation

4194- Lut,  Zeax,    Effect of macular pigment carotenoids on cognitive functions: A systematic review
- Review, NA, NA
*MPOD↑, Dietary lutein and zeaxanthin intake increased MPOD in six of the seven clinical trials and significantly improved most of the cognitive functions studied.
*cognitive↑,
*memory↑, Memory, processing speed, attention and reasoning were the cognitive function significantly related to MPOD levels in adults.

4191- Zeax,  Lut,    Effects of macular xanthophyll supplementation on brain-derived neurotrophic factor, pro-inflammatory cytokines, and cognitive performance
- Trial, AD, NA
*BDNF↑, BDNF, MPOD, serum MXans, and AOC all increased significantly versus placebo in both treatment groups over the 6-month study period (p < .05 for all).
*IL1β↓, IL-1β decreased significantly versus placebo in both treatment groups (p = .0036 and p = .006, respectively).
*cognitive↑, For cognitive measures, scores for composite memory, verbal memory, sustained attention, psychomotor speed, and processing speed all improved significantly in treatment groups
*memory↑, For cognitive scores, change in BDNF was correlated to change in composite memory (r = 0.32; p = .014) and verbal memory


Showing Research Papers: 1 to 7 of 7

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

MPOD↑, 3,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL1β↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

BDNF↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

eff↑, 2,  

Functional Outcomes(tgid=23) ⓘ

cognitive↑, 5,   memory↑, 7,   Mood↑, 2,   QoL↑, 1,  
Total Targets: 9

Scientific Paper Hit Count for: memory, memory
7 Lutein
7 Zeaxanthin
1 Vitamin E
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:348  Target#:558  State#:%  Dir#:2
  wNotes=on  sortOrder:rid,rpid

 

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