Database Query Results : Lutein, , Mood

Lut, Lutein: Click to Expand ⟱
Features:
Lutein
-Kale, spinach, parsley, corn, egg yolks, peas
-Breast cancer: Inverse correlation with dietary intake
- Potent antioxidant, scavenges ROS (reactive oxygen species)
-Downregulates NF-κB and other inflammatory pathways
-Promotes apoptosis in cancer cells
-inhibits angiogenesis
Mood, Behaviour: Click to Expand ⟱
Source:
Type:
Mood, including calmness vs aggression
Scientific Papers found: Click to Expand⟱
4232- Lut,    Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder
- in-vivo, NA, NA
*BDNF↑, provide novel evidence that luteolin treatment, by restoring microglia alterations and transiently boosting BDNF/TrkB signaling
*Mood↑, Treatment with Luteolin Ameliorates Behavioral Deficits in Cdkl5 +/− Mice
*neuroG↑, Treatment with Luteolin Promotes Neurogenesis in the Hippocampus of Cdkl5 +/− Mice
*TrkB↑, Treatment with Luteolin Transiently Boosts BDNF/TrkB Signaling Pathways in the Cortex of Cdkl5 +/− Mice

4231- Lut,    Luteolin and its antidepressant properties: From mechanism of action to potential therapeutic application
- Review, AD, NA
*PSD95↑, upregulating the expression of synaptophysin, postsynaptic density protein 95, brain-derived neurotrophic factor, B cell lymphoma protein-2, superoxide dismutase, and glutathione S-transferase; and decreasing the expression of malondialdehyde, caspa
*BDNF↑,
*SOD↑,
*GSTA1↑,
*MDA↑,
*Casp3↓,
*Mood↑, antidepressant effects of luteolin are mediated by various mechanisms, including anti-oxidative stress, anti-apoptosis, anti-inflammation, anti-endoplasmic reticulum stress, dopamine transport, synaptic protection, hypothalamic–pituitary–adrenal axi
*antiOx↑,
*Apoptosis↓,
*Inflam↓,
*ER Stress↓,

3982- Lut,  Zeax,    Nutritional Intervention to Prevent Alzheimer's Disease: Potential Benefits of Xanthophyll Carotenoids and Omega-3 Fatty Acids Combined
- Trial, AD, NA
*memory↑, Xanthophyll carotenoid concentration increases were significantly greater for Formulation 2 compared to Formulation 1 (p < 0.05), and progression of AD was less for this group (p = 0.003), with carers reporting functional benefits in memory, sight, a
*eff↑, positive outcomes for patients with AD who consumed a combination of xanthophyll carotenoids plus fish oil
*Mood↑,

3980- Lut,  Zeax,    Supplementation With Carotenoids, Omega-3 Fatty Acids, and Vitamin E Has a Positive Effect on the Symptoms and Progression of Alzheimer's Disease
- Trial, AD, NA
*eff↑, emonstrated statistically significant improvements in skin carotenoid measurements, blood carotenoids, ω-3FAs, and vitamin E concentrations (p < 0.05, for all).
*memory↑, active group also performed better in objective measures of AD severity (i.e., memory and mood), with a statistically significant difference reported in the clinical collateral for memory
*Mood↑,
*QoL↑, Exponential increases in the prevalence of AD and its relentless progressive nature is driving the need for interventions that help to ameliorate symptoms and improve quality of life in AD patients.

3977- Lut,  Zeax,    Dietary carotenoids related to risk of incident Alzheimer dementia (AD) and brain AD neuropathology: a community-based cohort of older adults
- Trial, AD, NA
*Aβ↓, Our findings support a beneficial role of total carotenoid consumption, in particular lutein/zeaxanthin, on AD incidence that may be related to the inhibition of brain β-amyloid deposition and fibril formation.
*cognitive↑, lutein-zeaxanthin showed additional inverse associations with AD diagnostic score, neuritic plaque severity, and neurofibrillary tangle density and severity.
*Mood↑, Participants in the lowest quintile of carotenoid intake had higher energy consumption, more depression symptoms, more diabetes and stroke diagnoses, and lower levels of physical activity,


* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Results for Effect on Cancer/Diseased Cells:

Total Targets: 0

Results for Effect on Normal Cells:
antiOx↑,1,   Apoptosis↓,1,   Aβ↓,1,   BDNF↑,2,   Casp3↓,1,   cognitive↑,1,   eff↑,2,   ER Stress↓,1,   GSTA1↑,1,   Inflam↓,1,   MDA↑,1,   memory↑,2,   Mood↑,5,   neuroG↑,1,   PSD95↑,1,   QoL↑,1,   SOD↑,1,   TrkB↑,1,  
Total Targets: 18

Scientific Paper Hit Count for: Mood, Behaviour
5 Lutein
3 Zeaxanthin
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:349  Target#:1362  State#:0  Dir#:2
  wNotes=on  sortOrder:rid,rpid

 

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