Database Query Results : Potassium, ,

K+, Potassium: Click to Expand ⟱
Features:
Potassium (K⁺), an essential electrolyte, plays vital roles in cellular function, neuronal signaling, and maintaining membrane potential.
-Source: leafy vegs, legumes, salmon(384mg), banana(358mg), potatoes(russet in skin)(550mg)
-RDA: 4700mg/d (<2% of US adults meet this goal)
AD:
-Low extracellular potassium can lead to increased neuronal calcium influx, oxidative damage, and microglial activation, worsening neurodegeneration.
-Certain potassium channels (e.g., KCNQ) are downregulated in AD, and their activators (like retigabine) have shown neuroprotective effects in preclinical models.

Cancer:
-K⁺ channels upregulated in many cancers

Those with kidney problems, may need to decrease potassium intake.
Scientific Papers found: Click to Expand⟱
4005- K+,    Potassium
- Review, Nor, NA - Review, Stroke, NA
*Risk↓, *Dose↝, *Risk↓, *BMD↑, *glucose↓,
4006- K+,    Rubidium and potassium levels are altered in Alzheimer's disease brain and blood but not in cerebrospinal fluid
- in-vitro, AD, NA
*other↓,
4007- K+,    The increased potassium intake improves cognitive performance and attenuates histopathological markers in a model of Alzheimer's disease
- in-vivo, AD, NA
*p‑tau↓, *cognitive↑, *Inflam↓, *ROS↓, *IL6↓, *4-HNE↓, *other↝,
4008- K+,    Potassium channels in the neuronal homeostasis and neurodegenerative pathways underlying Alzheimer's disease: An update
- Review, AD, NA
*other⇅,
4009- K+,    Na+ and K+ ion imbalances in Alzheimer’s disease
- Human, AD, NA
*other↝, *other↑,
4010- K+,    Potassium-sparing diuretics might reduce risk of Alzheimer's disease
- Review, AD, NA
*Risk↓, *ROS↓, *Inflam↓, *AntiAg↑,
4011- K+,    Sodium and potassium intakes among US adults: NHANES 2003–2008
- Analysis, NA, NA
*Dose↓, *eff↑, *BP↓,
4012- K+,    Abnormal potassium-channel function in platelets in Alzheimer's disease
- in-vivo, AD, NA
*other↑, *other↝,
4013- K+,    Apamin Improves Prefrontal Nicotinic Impairment in Mouse Model of Alzheimer's Disease
- in-vitro, AD, NA
*cognitive↑,
4014- K+,    The effects of boiling and leaching on the content of potassium and other minerals in potatoes
- Analysis, NA, NA
*other↓, *eff↑, *other↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 10

Results for Effect on Normal Cells:
4-HNE↓,1,   AntiAg↑,1,   BMD↑,1,   BP↓,1,   cognitive↑,2,   Dose↓,1,   Dose↝,1,   eff↑,2,   glucose↓,1,   IL6↓,1,   Inflam↓,2,   other↓,3,   other↑,2,   other⇅,1,   other↝,3,   Risk↓,3,   ROS↓,2,   p‑tau↓,1,  
Total Targets: 18

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:357  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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