No Product/Mechanism Only Cancer Research Results

NoProd, No Product/Mechanism Only: Click to Expand ⟱
Features:

No Product/Mechanism Only: This "No Product" entry is for entering research paper that discuss a target/pathway, and its effects, but does not mention a product
Scientific Papers found: Click to Expand⟱
6413- NoProd,    The DRP1 receptor FIS1 is critical to the expansion of triple-negative breast cancer tumor-initiating cells
- vitro+vivo, BC, MDA-MB-231 - in-vitro, BC, HS587T
FIS1↓, ROS∅, MMP∅, OXPHOS∅,
6414- NoProd,    Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
- Study, AD, NA
*eff↑, *DRP1/DNM1L↑, *FIS1↑,
6415- NoProd,    Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- in-vivo, AD, NA
*DRP1/DNM1L↓, *FIS1↑,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned ⓘ

FIS1↓, 1,  

Redox & Oxidative Stress ⓘ

OXPHOS∅, 1,   ROS∅, 1,  

Mitochondria & Bioenergetics ⓘ

MMP∅, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

DRP1/DNM1L↓, 1,   DRP1/DNM1L↑, 1,   FIS1↑, 2,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  
Total Targets: 4

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:405  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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