Terminalia bellirica / TAC Cancer Research Results

TBE, Terminalia bellirica: Click to Expand ⟱
Features:

Terminalia bellirica: The fruit extract contains multiple active constituents, including gallic acid, ellagic acid, corilagin, ethyl gallate, galloyl glucose, chebulagic acid and arjunolic acid.

Evidence level Primarily in vitro and animal evidence; limited human clinical evidence
Main research areas Inflammation, oxidative stress, metabolic effects, hepatoprotection and cancer
Primary preparation Fruit extract
Key constituents Gallic acid, ellagic acid, corilagin, chebulagic acid, ethyl gallate and related hydrolysable tannins


TAC, total antioxidant capacity: Click to Expand ⟱
Source:
Type:
Total antioxidant capacity (TAC) refers to the ability of a biological sample (such as blood, tissues, or food) to counteract oxidative stress by neutralizing free radicals and reactive oxygen species (ROS).

May have reduced levels in cancers.
Scientific Papers found: Click to Expand⟱
7036- TBE,  GA,    Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways
- in-vitro, Nor, THP1 - in-vitro, Nor, RAW264.7
*ROS↓, *MAPK↓, *NF-kB↓, *TAC↑, *NRF2↑, *Akt↑, *AMPK↑, *Inflam↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

NRF2↑, 1,   ROS↓, 1,   TAC↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   MAPK↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,   NF-kB↓, 1,  
Total Targets: 8

Scientific Paper Hit Count for: TAC, total antioxidant capacity
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:427  Target#:626  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page