Pomegranate/Punica granatum Cancer Research Results

Pom, Pomegranate/Punica granatum: Click to Expand ⟱
Features:

Punica granatum - Pomegranate

Type: Botanical extract / polyphenol- and ellagitannin-rich fruit

Active Constituents: Punicalagins, ellagic acid, ellagitannins, anthocyanins, flavonoids, and other polyphenols. Gut metabolism can generate urolithins from ellagitannins.

Function: Punica granatum extracts exhibit antioxidant, anti-inflammatory, antiproliferative, pro-apoptotic, antiangiogenic, and metabolic effects. Biological activity varies among juice, peel, seed, and standardized extract preparations.

Cancer: Experimental and clinical research has investigated pomegranate in prostate, breast, colorectal, and other cancers. Reported mechanisms include inhibition of proliferation, inflammation, angiogenesis, invasion, and metastasis and promotion of apoptosis.

Alzheimer's Disease: Experimental studies suggest neuroprotective activity through reduction of oxidative stress, neuroinflammation, amyloid-related pathology, and synaptic dysfunction. Pomegranate-derived polyphenols and their metabolites may contribute to these effects.
Scientific Papers found: Click to Expand⟱
7368- RS,  Amla,  CS,  Pom,  MP  Natural angiotensin converting enzyme inhibitors: A safeguard against hypertension, respiratory distress syndrome, and chronic kidney diseases
- Study, Nor, NA
*ACE↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

ACE↓, 1,  
Total Targets: 1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:444  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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