dietFMD, diet FMD Fasting Mimicking Diet: Click to Expand ⟱
Features:
5-day diet to mimic fasting without fasting.
FMDs are caloric-restricted plant–based diets containing low proteins, low sugar and high fats which represent a more feasible and safer option to water-only fasting.
Scientific Papers found: Click to Expand⟱
1853- dietFMD,    Impact of Fasting on Patients With Cancer: An Integrative Review
- Review, Var, NA
*toxicity∅, QoL∅, eff↑, eff↝, ChemoSideEff↓, TumCG↓, Dose↑, toxicity↝, eff↑, IGF-1↑, *OXPHOS↑, BG↓, Insulin↓, RadioS↑,
2352- dietFMD,    Glucose restriction reverses the Warburg effect and modulates PKM2 and mTOR expression in breast cancer cell lines
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF-7
Warburg↓, mTOR↓, PKM2↓,
2152- dietFMD,    Prolonged Nightly Fasting and Breast Cancer Prognosis
- Analysis, BC, NA
eff↑, Dose↓, Risk↓,
1863- dietFMD,  Chemo,    Effect of fasting on cancer: A narrative review of scientific evidence
- Review, Var, NA
eff↑, ChemoSideEff↓, ChemoSen↑, Insulin↓, HDAC↓, IGF-1↓, STAT5↓, BG↓, MAPK↓, HO-1↓, ATG3↑, Beclin-1↑, p62↑, SIRT1↑, LAMP2↑, OXPHOS↑, ROS↑, P53↑, DNAdam↑, TumCD↑, ATP↑, Treg lymp↓, M2 MC↓, CD8+↑, Glycolysis↓, GutMicro↑, GutMicro↑, Warburg↓, Dose↝,
1862- dietFMD,    Exceptional tumour responses to fasting-mimicking diet combined with standard anticancer therapies: A sub-analysis of the NCT03340935 trial
- Trial, Var, NA
OS↑,
1861- dietFMD,  Chemo,    Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models
- in-vitro, Colon, CT26 - in-vivo, NA, NA
selectivity↑, ChemoSen↑, BG↓, AminoA↓, Warburg↓, OCR↑, ATP↓, ROS↑, Apoptosis↑, GlucoseCon↓, PI3K↓, PTEN↑, GLUT1↓, GLUT2↓, HK2↓, PFK1↓, PKA↓, ATP:AMP↓, Glycolysis↓, lactateProd↓,
1860- dietFMD,  Chemo,    Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape
- in-vitro, BC, SUM159 - in-vitro, BC, 4T1
PI3K↑, Akt↑, mTOR↑, CDK4↑, CDK6↑, hyperG↓, TumCG↓, TumVol↓, Casp3↑, BG↓, eff↑, eff∅, PKA↓, KLF5↓, p‑GSK‐3β↑, Nanog↓, OCT4↓, KLF2↓, eff↑, ROS↑, BIM↑, ASK1↑, PI3K↑, Akt↑, mTOR↑, CDK1↓, CDK4↑, CDK6↑, eff↑,
1859- dietFMD,  Chemo,    Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity
- in-vitro, BC, 4T1 - in-vivo, Melanoma, B16-BL6
CLP↑, CD8+↑, TumCG↓, HO-1↓, TILs↑,
1858- dietFMD,  Chemo,    Effect of short-term fasting on the cisplatin activity in human oral squamous cell carcinoma cell line HN5 and chemotherapy side effects
- in-vitro, HNSCC, HN5
Apoptosis↑, necrosis↑,
1857- dietFMD,    Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
- in-vitro, BC, 4T1 - in-vivo, NA, NA
TumCG↓, ChemoSen↑, OS↑,
1856- dietFMD,  immuno,    Targeting the Gut Microbiome to Improve Immunotherapy Outcomes: A Review
- Review, Var, NA
GutMicro↑,
1855- dietFMD,    Impact of modified short-term fasting and its combination with a fasting supportive diet during chemotherapy on the incidence and severity of chemotherapy-induced toxicities in cancer patients - a controlled cross-over pilot study
- Trial, NA, NA
ChemoSideEff↓, QoL↑, IGF-1↓, Insulin↓,
1854- dietFMD,    How Far Are We from Prescribing Fasting as Anticancer Medicine?
- Review, Var, NA
ChemoSideEff↓, ChemoSen↑, IGF-1↓, IGFBP1↑, adiP↑, glyC↓, E-cadherin↑, MMPs↓, Casp3↑, ROS↑, ATP↓, AMPK↑, mTOR↓, ROS↑, Glycolysis↓, NADPH↓, OXPHOS↝, eff↑, eff↑, *RAS↓, *MAPK↓, *PI3K↓, *Akt↓, eff↑, ROS↑, Akt↑, Casp3↑,
1852- dietFMD,  Chemo,    Starvation Based Differential Chemotherapy: 
A Novel Approach for Cancer Treatment
- Review, Var, NA
ChemoSideEff↓, *toxicity↓, mTOR↓, IGF-1↓, IGFBP1↑, BG↓, ROS↑,
1851- dietFMD,  Chemo,    Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
- in-vitro, GBM, LN229 - in-vitro, neuroblastoma, SH-SY5Y
selectivity↑, selectivity↑, ROS↑, DNAdam↑, BG↓,
1850- dietFMD,    Fasting-mimicking diet remodels gut microbiota and suppresses colorectal cancer progression
- in-vivo, CRC, NA
TumCP↑, angioG↓, CD8+↑, GutMicro↑, eff↑,
1849- dietFMD,    The emerging role of fasting-mimicking diets in cancer treatment
- Review, Var, NA
TumCG↓, toxicity∅, BG↓, IGF-1↓, mTOR↓, M2 MC↓, eff↑, ChemoSen↑, QoL↑, RadioS↑, selectivity↑,
1848- dietFMD,  Chemo,    Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial
- Trial, BC, NA
ChemoSideEff↓, ChemoSen↑, eff↑,
1847- dietFMD,  VitC,    Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers
- in-vitro, PC, PANC1
TumCG↓, ChemoSen↑, eff↑, HO-1↓, Ferritin↓, Iron↑, ROS↑, TumCD↑, IGF-1↓, eff↓, eff↓,
1846- dietFMD,  VitC,    A fasting-mimicking diet and vitamin C: turning anti-aging strategies against cancer
- Study, Var, NA
TumCG↓, ChemoSen↑, ChemoSideEff↓, ROS↑, Fenton↑, H2O2↑, eff↑, HO-1↓, DNAdam↑, eff↑,
1845- dietFMD,    Fasting and fasting mimicking diets in cancer prevention and therapy
- Review, Var, NA
eff↑, selectivity↑, ChemoSen↑,
1844- dietFMD,    Unlocking the Potential: Caloric Restriction, Caloric Restriction Mimetics, and Their Impact on Cancer Prevention and Treatment
- Review, NA, NA
Risk↓, AMPK↑, Akt↓, mTOR↓, SIRT1↑, Hif1a↓, NRF2↓, SOD↑, ROS↑, IGF-1↓, p‑Akt↓, PI3K↑, GutMicro↑, OS↑, eff↝, ROS↑, TumCCA↑, *DNArepair↑, DNAdam↑,
1843- dietFMD,  BTZ,    Cyclic Fasting–Mimicking Diet Plus Bortezomib and Rituximab Is an Effective Treatment for Chronic Lymphocytic Leukemia
- in-vivo, CLL, NA
AntiTum↓, Apoptosis↑, IGF-1↓, eff↑, OS↑, eff↑,
1842- dietFMD,    Safety and Feasibility of Fasting-Mimicking Diet and Effects on Nutritional Status and Circulating Metabolic and Inflammatory Factors in Cancer Patients Undergoing Active Treatment
- Trial, Var, NA
Strength∅, Weight∅, IGF-1↓, IGFBP3↑, IGFBP1↑, eff↑,
1841- dietFMD,    Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer
- Trial, Var, NA
BG↓, AntiCan↑, IFN-γ↑, eff↑, Dose↝, CD14↓, IGF-1↓, IGFR↓, CD8+↑, NK cell↑,
1626- STF,  dietFMD,    When less may be more: calorie restriction and response to cancer therapy
- Review, Var, NA
CRM↑, ChemoSen↑, RadioS↑, eff↑, eff↑, IGF-1↓, TumCG↓, AMPK↑, eff↑, ChemoSen↑, RadioS↑, ROS↑, DNAdam↑, eff↑, HO-1↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 26

Results for Effect on Cancer/Diseased Cells:
adiP↑,1,   Akt↓,1,   Akt↑,3,   p‑Akt↓,1,   AminoA↓,1,   AMPK↑,3,   angioG↓,1,   AntiCan↑,1,   AntiTum↓,1,   Apoptosis↑,3,   ASK1↑,1,   ATG3↑,1,   ATP↓,2,   ATP↑,1,   ATP:AMP↓,1,   Beclin-1↑,1,   BG↓,8,   BIM↑,1,   Casp3↑,3,   CD14↓,1,   CD8+↑,4,   CDK1↓,1,   CDK4↑,2,   CDK6↑,2,   ChemoSen↑,11,   ChemoSideEff↓,7,   CLP↑,1,   CRM↑,1,   DNAdam↑,5,   Dose↓,1,   Dose↑,1,   Dose↝,2,   E-cadherin↑,1,   eff↓,2,   eff↑,25,   eff↝,2,   eff∅,1,   Fenton↑,1,   Ferritin↓,1,   GlucoseCon↓,1,   GLUT1↓,1,   GLUT2↓,1,   glyC↓,1,   Glycolysis↓,3,   p‑GSK‐3β↑,1,   GutMicro↑,5,   H2O2↑,1,   HDAC↓,1,   Hif1a↓,1,   HK2↓,1,   HO-1↓,5,   hyperG↓,1,   IFN-γ↑,1,   IGF-1↓,11,   IGF-1↑,1,   IGFBP1↑,3,   IGFBP3↑,1,   IGFR↓,1,   Insulin↓,3,   Iron↑,1,   KLF2↓,1,   KLF5↓,1,   lactateProd↓,1,   LAMP2↑,1,   M2 MC↓,2,   MAPK↓,1,   MMPs↓,1,   mTOR↓,5,   mTOR↑,2,   NADPH↓,1,   Nanog↓,1,   necrosis↑,1,   NK cell↑,1,   NRF2↓,1,   OCR↑,1,   OCT4↓,1,   OS↑,4,   OXPHOS↑,1,   OXPHOS↝,1,   P53↑,1,   p62↑,1,   PFK1↓,1,   PI3K↓,1,   PI3K↑,3,   PKA↓,2,   PKM2↓,1,   PTEN↑,1,   QoL↑,2,   QoL∅,1,   RadioS↑,4,   Risk↓,2,   ROS↑,13,   selectivity↑,5,   SIRT1↑,2,   SOD↑,1,   STAT5↓,1,   Strength∅,1,   TILs↑,1,   toxicity↝,1,   toxicity∅,1,   Treg lymp↓,1,   TumCCA↑,1,   TumCD↑,2,   TumCG↓,8,   TumCP↑,1,   TumVol↓,1,   Warburg↓,3,   Weight∅,1,  
Total Targets: 108

Results for Effect on Normal Cells:
Akt↓,1,   DNArepair↑,1,   MAPK↓,1,   OXPHOS↑,1,   PI3K↓,1,   RAS↓,1,   toxicity↓,1,   toxicity∅,1,  
Total Targets: 8

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:79  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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