SSBP1 Cancer Research Results

SSBP1, single-stranded DNA binding protein 1: Click to Expand ⟱

Source:

Type:

<span class="wphighlight">SSBP1</span> (Single-Stranded DNA-Binding Protein 1) and Cancer — Mitochondrial Genome Stability, Metabolic Fitness, and Stress Tolerance<br>
<b>While many studies</b> suggest that altered <span class="wphighlight">SSBP1</span> expression is linked to tumor aggressiveness and patient outcomes, the direction of change (upregulation or downregulation) and the prognostic implications can vary between cancer types. For instance:<br>
<br>
• In breast and colorectal cancers, lower <span class="wphighlight">SSBP1</span> expression has been associated with enhanced invasiveness and poorer prognosis.<br>
<br>
• In lung cancer, higher <span class="wphighlight">SSBP1</span> expression in some studies correlates with more aggressive disease features and unfavorable outcomes.<br>

Scientific Papers found: Click to Expand⟱

1208-

SANG,

Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3 to the single-stranded DNA-binding protein 1 (SSBP1) promoter region

in-vitro,

OS,

SSBP1↑, mtDam↑, Apoptosis↑, JAK↓, STAT3↓, PI3k/Akt/mTOR↓, ROS↑, MMP↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Immune & Inflammatory Signaling ⓘ

JAK↓, 1,
Total Targets: 8

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: SSBP1, single-stranded DNA binding protein 1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1047  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

SSBP1 Cancer Research Results

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

Mitochondria & Bioenergetics ⓘ

Core Metabolism/Glycolysis ⓘ

Cell Death ⓘ

Proliferation, Differentiation & Cell State ⓘ

Immune & Inflammatory Signaling ⓘ

Pathway results for Effect on Normal Cells:

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