VDR Cancer Research Results

VDR, Vitamin D receptor: Click to Expand ⟱
Source:
Type:
Vitamin D receptor

- Higher VDR expression in breast tumors is associated with a better prognosis.
- In colorectal cancer, reduced VDR expression has been frequently linked to more advanced disease and poorer outcomes.
- VDR expression can inhibit prostate cancer cell growth by slowing proliferation and promoting differentiation.
Scientific Papers found: Click to Expand⟱
8466- Mg,    Investigating the potential selective effects of a Kiperin multi-component magnesium supplement on colon cancer and normal cells
- in-vitro, Colon, HCT116 - in-vitro, Nor, CCD-18Co
tumCV↓, TumCMig⇅, *ROS↓, ROS↓, *VDR↑, *TNF-α↓,
1496- SFN,  VitD3,    Association between histone deacetylase activity and vitamin D-dependent gene expressions in relation to sulforaphane in human colorectal cancer cells
- in-vitro, CRC, Caco-2
eff↑, VDR↑, CYP11A1↓, HDAC↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

HDAC↓, 1,   tumCV↓, 1,  

Migration(tgid=13) ⓘ

TumCMig⇅, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CYP11A1↓, 1,   VDR↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

eff↑, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

TNF-α↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

VDR↑, 1,  
Total Targets: 3

Scientific Paper Hit Count for: VDR, Vitamin D receptor
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1111  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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