FOXO1 Cancer Research Results

FOXO1, Forkhead box O1: Click to Expand ⟱
Source:
Type:
FOXO-1 contributes to cellular homeostasis by regulating genes involved in apoptosis, cell cycle arrest, and metabolism.

– In many cancers, FOXO-1 activity can be reduced via genetic or epigenetic mechanisms, altered subcellular localization (e.g., cytoplasmic sequestration following phosphorylation by Akt), or protein degradation.
– This loss of nuclear FOXO-1 activity is often associated with diminished tumor suppressor functions.
– Decreased nuclear FOXO-1 expression or activity correlates with higher tumor grade and poorer prognosis.

– FOXO-1 is a key downstream target of the PI3K/Akt pathway. Hyperactivation of Akt, common in many cancers, leads to FOXO-1 inactivation.
Scientific Papers found: Click to Expand⟱
3433- ALA,    Alpha lipoic acid promotes development of hematopoietic progenitors derived from human embryonic stem cells by antagonizing ROS signals
- in-vitro, Nor, NA
*ROS↓, *Apoptosis↓, *Hif1a↑, *FOXO1↑, *FOXO3↑, *ATM↑, *SIRT1↑, *SIRT3↑, *CD34↑,
5692- BJ,    Seed oil of Brucea javanica induces apoptosis through the PI3K/Akt signaling pathway in acute lymphocytic leukemia Jurkat cells
- vitro+vivo, AML, NA
Apoptosis↑, Akt↓, P53↑, FOXO1↑, GSK‐3β↑, TumVol↓, QoL↑, BBB↑, OS↑, Dose↝, MMP↓, ROS↑, XIAP↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, TumCCA↑,
6215- CUR,    Curcumin: biochemistry, pharmacology, advanced drug delivery systems, and its epigenetic role in combating cancer
- Review, Var, NA
*antiOx↑, *Inflam↓, *BioAv↓, NF-kB↓, PI3K↓, Akt↓, Wnt↓, β-catenin/ZEB1↓, DNMTs↓, TumCI↓, TumMeta↓, *CompStab↑, *BioAv↑, angioG↓, VEGF↓, MMPs↓, *ROS↓, *SOD↑, *Catalase↑, *GSTs↑, *HO-1↑, *NRF2↑, mTOR↓, GSK‐3β↓, FOXO1↓, *radioP↑, *IL1↓, *IL6↓, *TNF-α↓, HATs↓, HDAC↓, ROS↑, ROS↑, MMP↓, Casp↑, Cyt‑c↑, COX1↓, COX2/PTGS2↓, PGE2↓, *cytoP450↓, ChemoSen↑, cardioP↑, Synergy↑,
3246- EGCG,    Epigallocatechin gallate suppresses hepatic cholesterol synthesis by targeting SREBP-2 through SIRT1/FOXO1 signaling pathway
- in-vitro, Nor, NA
*MDA↓, *SOD↑, *SIRT1↑, *FOXO1↑, *SREBP2↓,
7565- HYP,    Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review
- Review, AD, NA
*Inflam↓, *antiOx↑, *neuroP↑, *lipid-P↓, *ROS↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *MDA↓, *BAX↓, *Casp3↓, *Catalase↑, *SOD↑, *GSH↑, *BDNF↑, *TrkB↑, *NGF↑, *BDNF↑, *NF-kB↓, *AChE↓, *H2S↑, Casp3↑, Apoptosis↑, NF-kB↓, AMPK↑, HO-1↑, MAPK↑, cl‑Casp3↑, cl‑Casp9↑, BAX↑, SOD?, Catalase↓, NRF2↓, NQO1↓, HO-1↓, Bcl-2↓, TumCCA↑, FOXO1↑, TumAuto↑, Akt↓, mTOR↓, P70S6K↓, BMP7/OP1↓, *cardioP↑, *hepatoP↑, *antiCG↑, *AntiThr↑, *Diar↓, *AntiFungal↑, *CYP2D6↓, *PDGFR-BB↓, *PDGFRB↓, *toxicity↓, *Half-Life↑,
7548- HYP,    Mechanistic evaluation of hyperoside against non-small cell lung cancer: a combined approach of network pharmacology and in vitro experimental validation
- in-vitro, NSCLC, A549
MMP9↓, cl‑Casp3↑, MAPK↑, EGFR↓, TumCP↓, p38↑, Apoptosis↑, BAX↑, ERK↓, FOXO1↓,
7551- HYP,    Hyperoside exhibits anticancer activity in non‑small cell lung cancer cells with T790M mutations by upregulating FoxO1 via CCAT1
- vitro+vivo, NSCLC, NA
TumCP↓, Apoptosis↑, FOXO1↑, CCAT1↓, TumCG↓,
9191- ITCs,  AITC,  BITC,  PEITC,  SFN  Molecular Targets of Isothiocyanates in Cancer: Recent Advances
- Review, Var, NA
Risk↓, TumCG↓, ROS↑, TumCCA↑, Apoptosis↑, Ingr?, chemoPv↑, P450↓, SXR↓, CYP3A4↓, NRF2↑, ARE↑, HO-1↑, p38↓, TrxR↑, Trx↑, NF-kB↓, AP-1↓, BioAv↑, Akt↓, STAT3↓, HDAC↓, VEGF↓, MMP2↓, Hif1a↓, CD31/PECAM-1↓, PI3K↓, PDK1 / PDPK1↓, mTOR↓, FOXO1↓, FOXO3↓, BIM↑, p27/CDKN1B↑, P21↑, HER2/EBBR2↓, EGFR↓, Bcl-xL↓, XIAP↓, ROS↓, Zeb1↓, Snail↓, E-cadherin↑, MMP2↓, MMP9↓, ROS↑, MMP↓, Casp↑, DNAdam↑, TumCCA↑, γH2AX↑, CSCs↓, OCT4↓, SOX2↓, Nanog↓, NOTCH2↑, selectivity↝, ETC↓, compI↓, compIII↓, OCR↓, Synergy↑, ChemoSen↑, RadioS↑, Synergy↑, Synergy↑, Synergy↑, Synergy↑, Synergy↑,
8384- LT,    Current situation and research progress of luteolin in the treatment of gastrointestinal malignant tumors
- Review, GC, NA
Apoptosis↑, TumAuto↑, TumCCA↑, EMT↓, *ROS↓, *antiOx↑, ROS↑, P53↑, LC3II↑, Beclin-1/ATG6↑, p‑MAP2K1/MEK1↓, p‑ERK↓, BAX↑, cl‑Casp3↑, Bcl-2↓, p‑MAPK↓, DNArepair↓, HMGB1↓, XRCC1↓, ERCC3↑, CycB/CCNB1↓, CDC2↓, p‑CHK1↑, TumCCA↑, TumCP?, Wnt↓, β-catenin/ZEB1↓, miR-384↑, PTN↓, MMP2↓, MMP3↓, MMP9↓, MMP16↓, Ferroptosis↑, GPx4↓, Synergy↑, Ki-67↓, GSH↓, ChemoSen↑, TumCP↓, TumCMig↓, TumCI↓, PI3K↓, Akt↓, mTOR↓, NF-kB↓, NOTCH↓, miR-139-5p↑, miR-34a↑, miR-422a↑, miR-107↑, miR-21↓, miR-155↓, miR-224↓, miR-340↓, E-cadherin↑, N-cadherin↓, Vim↓, HK1↓, FOXO1↓, compI↓, compIII↓, compV↓, ETC↓, BioAv↝,
8560- Matr,    Matrine: A Promising Natural Product With Various Pharmacological Activities
- Review, AD, NA - Review, Stroke, NA - Review, Var, NA
*antiAll↑, *Stroke↓, *AntiArt↑, TumCCA↑, VEGF↓, Apoptosis↑, P53↑, P21↑, PCNA↓, EIF4E↓, TumCP↓, TumCMig↓, IAP1↓, ROS↑, EMT↓, PAX2↓, ER Stress↑, HK2↓, Apoptosis↑, STAT3↓, mtDam↑, HMGB1↓, ChemoSen↑, p‑GSK‐3β↓, P-gp/ABCB1↓, MRP1/ABCC1↓, Vim↓, cycD1/CCND1↓, CDK4↓, GSH↓, SOD↓, mt-Cyt‑c↓, BAX↑, MMP9↓, MMP2↓, E-cadherin↓, N-cadherin↓, FOXO1↓, FOXO3↓, FOXO4↓, PI3K↓, ATF4↑, CHOP/DDIT3↑, *Aβ↓, *RAGE↓, *memory↑, *Learn↑, *cognitive↑, *MDA↓, *SOD↑, *GPx↑, *Catalase↑, *antiAll↑, *AHR↓, *SOCS-3↓, *ICAM-1↓, *ROS↓, cachexia↓, *BACE/β-secretase↓, *NF-kB↓, *TNF-α↓, *IL1β↓,
8555- Matr,    Matrine Exerts Pharmacological Effects Through Multiple Signaling Pathways: A Comprehensive Review
- Review, Var, NA
*AntiTum↑, *Inflam↓, *Analgesic↑, *AntiViral↑, *Imm↑, *PI3K↑, *Akt↑, *mTOR↑, TumAuto↑, PI3K↓, Akt↓, mTOR↓, Beclin-1/ATG6↑, E-cadherin↑, Vim↓, MMP2↓, MMP9↓, Snail↓, Slug↓, PTEN↑, TumCP↓, TumCMig↓, TumCI↓, ChemoSen↑, ROS↑, uPA↓, p‑ERK↓, cachexia↓, antiD↑, GSK‐3β↓, LC3B-II↑, p62↓, Apoptosis↑, Casp3↑, Casp8↑, Casp9↑, FOXO1↑, FOXO3↑, FOXO4↑, PARP↑, BIM↑, Bcl-2↓, survivin↓, miR-21↓, *HOTAIR↑, *p‑Akt↑, *p‑STAT3↑, *STAT3↑, *ROS↓, Wnt↓, β-catenin/ZEB1↓, NOTCH1↓, JAG1↓, HES1↓, BioAv↝, toxicity↝,
1678- PBG,  5-FU,  sericin,    In vitro and in vivo anti-colorectal cancer effect of the newly synthesized sericin/propolis/fluorouracil nanoplatform through modulation of PI3K/AKT/mTOR pathway
- in-vitro, CRC, Caco-2 - in-vivo, NA, NA
PI3K↓, Akt↓, mTOR↓, TumCP↓, Bcl-2↓, BAX↑, Casp3↑, Casp9↑, ROS↓, FOXO1↑, *toxicity∅, eff↑,
2443- RES,    Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review
- Review, Var, NA
*antiOx↑, *ROS↓, *PTEN↑, *Akt↓, *Catalase↑, *SOD↑, *ERK↓, *GSH↑, *AMPK↑, *FOXO1↝, *RNS↓, *Catalase↑, *cardioP↑, *PI3K↑, *eNOS↑, hepatoP↑,
3017- RosA,  Per,    Molecular Mechanism of Antioxidant and Anti-Inflammatory Effects of Omega-3 Fatty Acids in Perilla Seed Oil and Rosmarinic Acid Rich Fraction Extracted from Perilla Seed Meal on TNF-α Induced A549 Lung Adenocarcinoma Cells
- in-vitro, Lung, A549
TumCD∅, ROS↓, IL1β↓, IL6↓, IL8↓, TNF-α↓, COX2/PTGS2↓, SOD2↓, FOXO1↓, NF-kB↓, JNK↓, antiOx↑, tumCV∅,
3006- RosA,    Rosmarinic acid attenuates glioblastoma cells and spheroids’ growth and EMT/stem-like state by PTEN/PI3K/AKT downregulation and ERK-induced apoptosis
- in-vitro, GBM, U87MG - in-vitro, GBM, LN229
TumCG↓, EMT↓, SIRT1↓, FOXO1↓, NF-kB↓, angioG↓, ROS↓, PTEN↓, PI3K↓, Akt↓, *Inflam↓, *cardioP↑, *hepatoP↑, *neuroP↑, Warburg↓,
4833- Uro,    Unveiling the potential of Urolithin A in Cancer Therapy: Mechanistic Insights to Future Perspectives of Nanomedicine
- Review, Var, NA - Review, AD, NA - Review, IBD, NA
BioAv↝, TumAuto↝, TumCG↓, TumMeta↓, ChemoSen↑, Imm↑, RadioS↑, BioAv↑, other↝, eff↓, *antiOx↓, *Inflam↓, AntiCan↓, AntiAge↑, chemoP↑, *neuroP↑, *ROS↓, *cognitive↑, *lipid-P↓, *cardioP↑, *TNF-α↓, *IL6↓, GutMicro↑, TumCCA↑, Apoptosis↑, angioG↓, NF-kB↓, PI3K↓, Akt↓, Casp↑, survivin↓, TumCP↓, cycD1/CCND1↓, cMyc↑, BAX↑, Bcl-2↓, COX2/PTGS2↓, P53↑, p38↑, *ROS↓, *SOD↑, *GPx↑, SIRT1↑, FOXO1↑, eff↑, ChemoSen↑,
4836- Uro,    Urolithin-A Promotes CD8+ T Cell–mediated Cancer Immunosurveillance via FOXO1 Activation
- in-vitro, Var, NA
FOXO1↑, TumCG↓, PD-1↓, TIM-3↓,

Showing Research Papers: 1 to 17 of 17

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 17

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   ARE↑, 1,   Catalase↓, 1,   GPx4↓, 1,   GSH↓, 2,   HO-1↓, 1,   HO-1↑, 2,   NQO1↓, 1,   NRF2↓, 1,   NRF2↑, 1,   ROS↓, 4,   ROS↑, 8,   SOD?, 1,   SOD↓, 1,   SOD2↓, 1,   Trx↑, 1,   TrxR↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 1,   compI↓, 2,   compIII↓, 2,   compV↓, 1,   ETC↓, 2,   mtDam↑, 1,   OCR↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,   GSK‐3β↓, 2,   GSK‐3β↑, 1,   p‑GSK‐3β↓, 1,   HK1↓, 1,   HK2↓, 1,   PDK1 / PDPK1↓, 1,   SIRT1↓, 1,   SIRT1↑, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 10,   BAX↑, 6,   Bcl-2↓, 5,   Bcl-xL↓, 1,   BIM↑, 2,   Casp↑, 3,   Casp3↑, 4,   cl‑Casp3↑, 3,   Casp8↑, 2,   Casp9↑, 3,   cl‑Casp9↑, 1,   Cyt‑c↑, 1,   mt-Cyt‑c↓, 1,   Ferroptosis↑, 1,   IAP1↓, 1,   p38↓, 1,   p38↑, 2,   survivin↓, 2,   TumCD∅, 1,   XIAP↓, 1,   XIAP↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 9,   EGFR↓, 2,   ERK↓, 1,   p‑ERK↓, 2,   HER2/EBBR2↓, 1,   JNK↓, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↑, 2,   p‑MAPK↓, 1,   mTOR↓, 6,   P70S6K↓, 1,   PI3K↓, 8,   PTEN↓, 1,   PTEN↑, 1,   STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   cMyc↑, 1,   DNMTs↓, 1,   FOXO1↓, 7,   FOXO1↑, 7,   FOXO3↓, 2,   FOXO3↑, 1,   FOXO4↓, 1,   FOXO4↑, 1,   HATs↓, 1,   HDAC↓, 2,   HES1↓, 1,   miR-107↑, 1,   miR-139-5p↑, 1,   miR-155↓, 1,   miR-21↓, 2,   miR-224↓, 1,   miR-340↓, 1,   miR-34a↑, 1,   miR-384↑, 1,   miR-422a↑, 1,   OCT4↓, 1,   other↝, 1,   PAX2↓, 1,   SOX2↓, 1,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   ER Stress↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 2,   LC3B-II↑, 1,   LC3II↑, 1,   p62↓, 1,   TumAuto↑, 3,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   DNArepair↓, 1,   ERCC3↑, 1,   P53↑, 4,   PARP↑, 1,   cl‑PARP↑, 1,   PCNA↓, 1,   XRCC1↓, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 1,   p‑CHK1↑, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 2,   Ki-67↓, 1,   P21↑, 2,   p27/CDKN1B↑, 1,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP7/OP1↓, 1,   CSCs↓, 1,   EIF4E↓, 1,   JAG1↓, 1,   Ki-67↓, 1,   Nanog↓, 1,   NOTCH↓, 1,   NOTCH1↓, 1,   NOTCH2↑, 1,   TumCG↓, 5,   TumCP?, 1,   TumCP↓, 7,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

AP-1↓, 1,   CCAT1↓, 1,   E-cadherin↓, 1,   E-cadherin↑, 3,   EMT↓, 3,   MMP16↓, 1,   MMP2↓, 5,   MMP3↓, 1,   MMP9↓, 5,   MMPs↓, 1,   N-cadherin↓, 2,   Slug↓, 1,   Snail↓, 2,   TumCI↓, 3,   TumCMig↓, 3,   TumMeta↓, 2,   uPA↓, 1,   Vim↓, 3,   Zeb1↓, 1,   β-catenin/ZEB1↓, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 3,   CD31/PECAM-1↓, 1,   Hif1a↓, 1,   VEGF↓, 3,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   MMP↓, 3,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2/PTGS2↓, 3,   HMGB1↓, 2,   IL1β↓, 1,   IL6↓, 1,   IL8↓, 1,   Imm↑, 1,   NF-kB↓, 7,   PD-1↓, 1,   PGE2↓, 1,   TIM-3↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

PTN↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

SXR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 2,   BioAv↝, 3,   ChemoSen↑, 7,   CYP3A4↓, 1,   Dose↝, 1,   eff↓, 1,   eff↑, 2,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 1,   P450↓, 1,   RadioS↑, 2,   selectivity↝, 1,   Synergy↑, 8,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 2,   HER2/EBBR2↓, 1,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 1,   antiD↑, 1,   cachexia↓, 2,   cardioP↑, 1,   chemoP↑, 1,   chemoPv↑, 1,   hepatoP↑, 1,   OS↑, 1,   QoL↑, 1,   Risk↓, 1,   toxicity↝, 1,   TumVol↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 1,  
Total Targets: 205

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 4,   Catalase↑, 5,   GPx↑, 2,   GSH↑, 2,   GSTs↑, 1,   HO-1↑, 1,   lipid-P↓, 2,   MDA↓, 3,   NRF2↑, 1,   RNS↓, 1,   ROS↓, 9,   SOD↑, 6,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,   cytoP450↓, 1,   H2S↑, 1,   SIRT1↑, 2,   SREBP2↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   BAX↓, 1,   Casp3↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 1,   p‑Akt↑, 1,   ERK↓, 1,   mTOR↑, 1,   PDGFR-BB↓, 1,   PDGFRB↓, 1,   PI3K↑, 2,   PTEN↑, 1,   STAT3↑, 1,   p‑STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   FOXO1↑, 2,   FOXO1↝, 1,   FOXO3↑, 1,   HOTAIR↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD34↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

eNOS↑, 1,   Hif1a↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ICAM-1↓, 1,   IL1↓, 1,   IL1β↓, 2,   IL6↓, 3,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 5,   NF-kB↓, 2,   RAGE↓, 1,   SOCS-3↓, 1,   TNF-α↓, 4,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BDNF↑, 2,   NGF↑, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   BACE/β-secretase↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,   CompStab↑, 1,   CYP2D6↓, 1,   Half-Life↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

IL6↓, 3,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   antiAll↑, 2,   AntiArt↑, 1,   antiCG↑, 1,   AntiTum↑, 1,   cardioP↑, 4,   cognitive↑, 2,   hepatoP↑, 2,   Learn↑, 1,   memory↑, 1,   neuroP↑, 3,   radioP↑, 1,   Stroke↓, 1,   toxicity↓, 1,   toxicity∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   AntiViral↑, 1,   Diar↓, 1,  
Total Targets: 85

Scientific Paper Hit Count for: FOXO1, Forkhead box O1
3 Hyperoside
2 Matrine
2 Rosmarinic acid
2 Urolithin
1 Alpha-Lipoic-Acid
1 Brucea javanica
1 Curcumin
1 EGCG (Epigallocatechin Gallate)
1 Isothiocyanates
1 Allyl isothiocyanate
1 Benzyl isothiocyanate
1 Phenethyl isothiocyanate
1 Sulforaphane (mainly Broccoli)
1 Luteolin
1 Propolis -bee glue
1 5-fluorouracil
1 sericin
1 Resveratrol
1 Perilla
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1164  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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