chemoP Cancer Research Results

chemoP, ChemoProtective: Click to Expand ⟱
Source:
Type:
Protects normal cells against the effect of Chemo.
Scientific Papers found: Click to Expand⟱
5444- AG,    A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine
- Review, Var, NA
*Imm↑, *antiOx↑, *Inflam↓, AntiTum↑, eff↑, chemoP↑, Dose↝, TumCMig↓, TumCP↓, Akt↓, GSK‐3β↓, MMP2↓, MMP9↓, EMT↓, PI3K↓, Akt↓, NF-kB↓, Inflam↓, TGF-β1↓, TNF-α↓, IL6↓, Fas↓, FasL↓, NOTCH1↓, JNK↓, TumCG↓,
5428- AG,    Meta-Analysis of Astragalus-Containing Traditional Chinese Medicine Combined With Chemotherapy for Colorectal Cancer: Efficacy and Safety to Tumor Response
- Review, CRC, NA
ChemoSen↑, chemoP↑, QoL↑, RenoP∅, hepatoP∅,
5429- AG,    Astragalus polysaccharides improve adjuvant chemotherapy-induced fatigue for patients with early breast cancer
- Human, BC, NA
chemoP↑, other↝,
5434- AG,    Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview
- Review, Liver, NA
AntiCan↑, Apoptosis↑, TumCP↓, EMT↓, Imm↑, ChemoSen↑, BioAv↓, TumCG↓, IL2↑, IL12↑, TNF-α↑, P-gp/ABCB1↓, MDR1↓, QoL↑, Casp↑, DNAdam↑, Bcl-2↓, BAX↑, MMP↓, Cyt‑c↑, NOTCH1↓, GSK‐3β↓, TumCCA↑, GSH↓, ROS↑, lipid-P↑, c-Iron↑, GPx4↓, ACSL4↑, Ferroptosis↑, Wnt↓, β-catenin/ZEB1↓, cycD1/CCND1↓, Akt↓, PI3K↓, mTOR↓, CXCR4↓, Vim↓, PD-L1↓, eff↑, eff↑, ChemoSen↑, ChemoSen↑, chemoP↑,
4413- AgNPs,  Anzaroot,    Green synthesis of silver nanoparticles from plant Astragalus fasciculifolius Bioss and evaluating cytotoxic effects on MCF7 human breast cancer cells
- in-vitro, BC, MCF7
chemoP↑, TumCG↓, eff↑, CellMemb↑, selectivity↑, ROS↑, P53↑,
5356- AL,    Therapeutic role of allicin in gastrointestinal cancers: mechanisms and safety aspects
- Review, GC, NA
Apoptosis↑, TumCP↓, MAPK↓, PI3K↓, Akt↓, NF-kB↓, AntiCan↑, ChemoSen↑, TumCCA↑, Apoptosis↑, BioAv↑, selectivity↑, TGF-β↓, ROS↑, DNAdam↑, p‑P53↑, P21↑, cycD1/CCND1↓, cycE/CCNE↓, CDK4↓, CDK6↓, MMP↓, NF-kB↑, BAX↑, Bcl-2↓, ER Stress↑, Casp↑, AIF↑, Fas↑, Casp8↑, Cyt‑c↑, cl‑PARP↑, Ca+2↑, *NRF2↑, *chemoP↑, *GutMicro↑, CycB/CCNB1↑, H2S↑, HIF-1↓, RadioS↑,
2646- AL,    Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress
- in-vitro, Pca, DU145 - in-vitro, Melanoma, RPMI-8226
AntiCan↑, eff↓, ChemoSen↑, ER Stress↑, tumCV↓, DNAdam↑, GSH∅, HSP70/HSPA5↓, UPR↑, β-catenin/ZEB1↓, ROS↑, HO-2↑, SIRT1↑, GlucoseCon∅, lactateProd∅, chemoP↑,
2658- AL,    The Toxic Effect Ways of Allicin on Different Cell Lines
- Review, Var, NA
*antiOx↑, *AntiAg↑, *cardioP↑, Ca+2↑, ROS↑, Casp↑, p38↑, MAPK↑, hepatoP↑, chemoP↑,
2660- AL,    Allicin: A review of its important pharmacological activities
- Review, AD, NA - Review, Var, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2/PTGS2↓, *IL6↓, *TNF-α↓, *MPO↓, *Synergy↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2/KDR/Flk1↓, p‑FAK↓,
2667- AL,    Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment
- Review, GC, NA
AntiCan↑, ChemoSen↑, angioG↓, chemoP↑, *GutMicro↑, *antiOx↑, other↝, GSH↓, Thiols↓, *ROS↓, *hepatoP↑, *Inflam↓, *NF-kB↓,
3456- ALA,    Renal-Protective Roles of Lipoic Acid in Kidney Disease
- Review, Nor, NA
*RenoP↑, *ROS↓, *antiOx↑, *Inflam↓, *Sepsis↓, *IronCh↑, *BUN↓, *creat↓, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *chemoP↑, *eff↑, *NF-kB↓,
1235- ALA,  Cisplatin,    α-Lipoic acid prevents against cisplatin cytotoxicity via activation of the NRF2/HO-1 antioxidant pathway
- in-vitro, Nor, HEI-OC1 - ex-vivo, NA, NA
ROS↑, HO-1↓, *toxicity↓, chemoP↑, *ROS↓, *HO-1↑, *SOD1↑, *NRF2↑,
6401- ANE,    Anethole and Its Role in Chronic Diseases
- Review, Var, NA - Review, PSA, NA
*BioAv↝, *other↝, CompStab↓, TNF-α↓, IL10↑, CXCR4↓, MMP2↓, MMP9↓, TIMP1↑, NF-kB↓, AP-1↓, STAT↓, JNK↓, ERK↓, MAPK↓, PI3K↓, Akt↓, JAK↓, *AntiDiabetic↓, *neuroP↑, *Imm↑, chemoP↑, *AntiThr↑, *AntiAg↑, *antiOx↑, *SOD↑, *GSH↑, *Wound Healing↑, chemoPv↑, *GSTs↑, *NF-kB↓,
4760- antiOx,  Chemo,    Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials
- Review, Var, NA
ChemoSen∅, OS↑, chemoP↑,
4765- antiOx,  Chemo,    Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity – Exploring the armoury of obscurity
- Review, Var, NA
chemoP↑, ChemoSen↑, OS↑, Dose↑, Risk↓, eff↓,
2584- Api,  Chemo,    The versatility of apigenin: Especially as a chemopreventive agent for cancer
- Review, Var, NA
ChemoSen↑, RadioS↑, eff↝, DR5↑, selectivity↑, angioG↓, selectivity↑, chemoP↑, MAPK↓, PI3K↓, Akt↓, mTOR↓, Wnt↓, β-catenin/ZEB1↓, GLUT1↓, radioP↑, CompStab↓, chemoPv↑,
1999- Api,  doxoR,    Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation
- in-vitro, Nor, NRK52E - in-vitro, Nor, MPC5 - in-vitro, BC, 4T1 - in-vivo, NA, NA
neuroP↑, ChemoSen∅, RenoP↑, selectivity↑, chemoP↑, ROS↑, *ROS∅, *antiOx↑, *toxicity↓,
5396- Ash,    Withania Somnifera (Ashwagandha) and Withaferin A: Potential in Integrative Oncology
- Review, Var, NA
selectivity↑, ROS↑, Apoptosis↑, ChemoSen↑, RadioS↑, NF-kB↓, ER-α36↓, P53↑, *ROS∅, γH2AX↑, DNAdam↑, MMP↓, XIAP↓, IAP1↓, survivin↓, SOD↓, Dose↝, IL6↓, TNF-α↓, COX2/PTGS2↓, p‑Akt↓, NOTCH1↓, FOXO↑, Casp↑, MMP2↓, CSCs↓, *ROS↓, *SOD2↑, chemoP↑, ChemoSen↑, RadioS↑,
2002- Ash,    Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology
- Review, Var, NA
antiOx↑, Inflam↓, TumCP↓, OS↑, RadioS↑, radioP↑, chemoP↑,
8806- Ash,    Systematic review and network meta-analysis of the effects of plant active substance on quality of life in breast cancer patients
- Review, BC, NA
Dose?, QoL↑, fatigue↓, Pain↓, Nausea↓, chemoP↑,
4804- ASTX,    Astaxanthin in cancer therapy and prevention (Review)
- Review, Var, NA - Review, AD, NA
*antiOx↑, *Inflam↓, ChemoSen⇅, chemoP↑, BioAv↑, TumCP↑, ROS⇅, Apoptosis↑, PI3K↑, Akt↑, GSK‐3β↑, NRF2↑, AntiCan↑, *neuroP↑, Synergy↑, AntiTum↑,
4807- ASTX,    An overview of the anticancer activity of astaxanthin and the associated cellular and molecular mechanisms
- Review, Var, NA
*antiOx↑, *neuroP↑, AntiCan↑, TumCG↓, TumCD↑, TumCMig↓, ChemoSen↑, chemoP↑, *BioAv↓, TumCP↓, TumCCA↑, Apoptosis↑, BioAv↑,
5427- ASTX,    Astaxanthin and Cancer Chemoprevention
- Review, Var, NA
chemoP↑, AntiCan↑, chemoPv↑, Risk↓, lipid-P↓, Pain↓, BioAv↑, Dose↝,
5447- ATV,    The Mevalonate Pathway, a Metabolic Target in Cancer Therapy
- Review, Var, NA
Risk↓, Dose↑, ChemoSen↑, chemoP↑, HMG-CoA↓, EMT↓, CSCs↓, HH↝, YAP/TEAD↝,
5568- B-Gluc,  immuno,    Beta-glucans in oncology: revolutionizing treatment with immune power & tumor targeting
- Review, Var, NA
TNF-α↓, IL6↓, NF-kB↓, PD-L1↓, Imm↑, BAX↑, Bcl-2↓, TumCCA↑, angioG↓, VEGF↓, MMPs↓, OS↑, chemoP↑, eff↑, BioAv↑,
5579- B-Gluc,    Fungal beta-glucans as adjuvants for treating cancer patients – A systematic review of clinical trials
- Review, Var, NA
*toxicity↓, Imm↑, radioP↑, chemoP↑,
2597- Ba,    Baicalein – An Intriguing Therapeutic Phytochemical in Pancreatic Cancer
- Review, PC, NA
chemoP↑, ChemoSen↑, 12LOX?, Bcl-2↓, BAX↑, Mcl-1↓, ERK↓, Prx6↑, Dose↝, BioAv↓, eff↑,
2022- BBR,  GoldNP,  Rad,    Berberine-loaded Janus gold mesoporous silica nanocarriers for chemo/radio/photothermal therapy of liver cancer and radiation-induced injury inhibition
- in-vitro, Liver, SMMC-7721 cell - in-vitro, Nor, HL7702
*toxicity↓, radioP↑, BioAv↑, AntiTum↑, selectivity↑, eff↑, chemoP↑,
6503- BCP,    The Potential Therapeutic Role of Beta-Caryophyllene as a Chemosensitizer and an Inhibitor of Angiogenesis in Cancer
- Review, Var, NA
ChemoSen↑, angioG↓, TumCI↓, TumMeta↓, ROS↑, *ROS↓, chemoP↑, CB2 / CNR2↑, Inflam↓, AntiTum↑, *BioAv↑, *BBB↑, Apoptosis↑, TumCP↑, TumCCA↑, RadioS↑, DNArepair↓, ROS↑, STAT3↓, *BioEnh↑, Pain↓, AntiBio↓, ROS↑, Dose↝, NF-kB↓, MAPK↓, TNF-α↓, IL1β↓, IL6↓, cl‑PARP↑, Casp↑, BAX↑, Bcl-2↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP2↓, p‑p38↓, p‑ERK↓, EPR↑, P-gp/ABCB1↓, MRP1/ABCC1↓, *NRF2↑, *antiOx↑,
2727- BetA,    Betulinic acid in the treatment of breast cancer: Application and mechanism progress
- Review, BC, NA
mt-ROS↑, Sp1/3/4↓, TumMeta↓, GlucoseCon↓, NF-kB↓, ChemoSen↑, chemoP↑, m-Apoptosis↑, TOP1↓,
5686- BJ,  BRU,    A review of Brucea javanica: metabolites, pharmacology and clinical application
- Review, Var, NA
AntiTum↑, other↝, ChemoSen↑, QoL↑, chemoP↑, *Inflam↓, NF-kB↓, TumCP↓, TumCI↓, TumMeta↓, Hif1a↓, NRF2↓, STAT3↓, COX2/PTGS2↓, Casp3↑, Casp9↑, ROS↑, EGFR↓, NRF2↑,
5681- BML,    Supplementation Containing Bromelain on the Side Effects of Oncological Treatment: Systematic Review
- Review, Var, NA
Inflam↓, chemoP↑,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *Synergy↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,
3512- Bor,    Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake
- in-vitro, Pca, DU145
TumCP↓, eIF2α↑, ATF4↑, ATF6↑, GADD34↑, CHOP/DDIT3↓, GRP78/BiP↑, GRP94↑, Risk↓, *BMD↑, Ca+2↓, *Half-Life↝, IRE1∅, chemoP↑,
5702- BRU,  BJ,    Brusatol inhibits metastasis of triple-negative breast cancer through metabolic reprogramming
- in-vitro, BC, NA
AntiTum↑, PPP↓, Glycolysis↓, TCA↓, NADPH↓, ROS↑, chemoP↑, e-LDH↑, TumMeta↓, Glycolysis↓,
6554- BSB,  doxoR,    α-Bisabolol: A Dietary Sesquiterpene that Attenuates Apoptotic and Nonapoptotic Cell Death Pathways by Regulating the Mitochondrial Biogenesis and Endoplasmic Reticulum Stress–Hippo Signaling Axis in Doxorubicin-Induced Acute Cardiotoxicity in Rats
- in-vivo, Nor, NA
*cardioP↑, *chemoP↑, *antiOx↑, *ROS↓, *toxicity↓, *DNAdam↓, *lipid-P↓, *ER Stress↓,
5744- Buty,  PacT,    Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction
- in-vivo, Var, NA
chemoP↑, neuroP↑, Inflam↓, GutMicro↑, *ROS↓, Dose↝,
5739- Buty,    Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic (Review)
- Review, Var, NA
GutMicro↑, *Inflam↓, *IL6↓, *TNF-α↓, *IL17↓, *IL10↑, *ROS↝, COX2/PTGS2↓, NLRP3↓, Imm↑, HDAC↓, TumCCA↑, Apoptosis↑, ROS↑, Casp↑, mtDam↑, Cyt‑c↑, eff↑, chemoP↑, ChemoSen↑, Synergy↑, RadioS↑, HCAR2↑,
5872- CA,    Nrf2/ARE-Mediated Antioxidant Actions of Pro-Electrophilic Drugs
- Review, Nor, NA
*NRF2↑, *GSH↑, *neuroP↑, *Inflam↓, *cardioP↑, *Obesity↓, *angioG↓, chemoP↑, *NF-kB↓,
5758- CAPE,  PBG,    Caffeic acid phenethyl ester and therapeutic potentials
- Review, Var, NA
*antiOx↑, *Inflam↓, ChemoSen↑, chemoP↑, COX1↓, COX2/PTGS2↓, selectivity↑, NF-kB↓, RadioS↑, *ROS↓, *lipid-P↓,
5887- CAR,  TV,    Antitumor Effects of Carvacrol and Thymol: A Systematic Review
- Review, Var, NA
Apoptosis↑, TumCCA↑, TumMeta↓, TumCP↓, MAPK↓, PI3K↓, Akt↓, mTOR↓, eff↑, *Inflam↓, *antiOx↑, AXL↓, MDA↑, Casp3↑, Bcl-2↓, MMP2↓, MMP9↓, p‑JNK↑, BAX↑, MDA↓, TRPM7↓, MMP↓, Cyt‑c↑, Casp↑, cl‑PARP↑, ROS↑, CDK4↓, P21↑, F-actin↓, GSH↓, *SOD↑, *Catalase↑, *GPx↑, *GSR↑, *GSH↑, *lipid-P↓, *AST↓, *ALAT↓, *ALP↓, *LDH↓, DNAdam↑, AFP↓, VEGF↓, Weight↑, *chemoP↑, ROS↑,
5888- CAR,    Therapeutic application of carvacrol: A comprehensive review
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Park, NA
*antiOx↑, *AntiCan↑, *AntiDiabetic↑, *cardioP↑, *Obesity↓, *hepatoP↑, *AntiAg↑, *Bacteria↓, *Imm↑, MMP2↓, MMP9↓, Apoptosis↓, MMP↓, ERK↓, PI3K↓, ALAT↓, *ROS↓, *Catalase↑, *SOD↑, *GPx↑, *AST↓, *LDH↓, *necrosis↓, ROS↑, TumCCA↑, CDK4↓, cycD1/CCND1↓, NOTCH↓, IL6↓, chemoP↑, *Pain↓, *neuroP↑, *TRPM7↓, *motorD↑, *NF-kB↓, *COX2/PTGS2↓, *MDA↓,
5919- Cats,  Cisplatin,    Uncaria tomentosa Leaves Decoction Modulates Differently ROS Production in Cancer and Normal Cells, and Effects Cisplatin Cytotoxicity
- in-vitro, Liver, HepG2
ROS↑, GSH↓, Apoptosis↑, Casp3↑, Casp7↑, NF-kB↓, selectivity↑, ChemoSen↑, chemoP↑,
6017- CGA,    Therapeutic Potential of Chlorogenic Acid in Chemoresistance and Chemoprotection in Cancer Treatment
- Review, Var, NA
AntiCan↑, *chemoP↑, TNF-α↓, COX2/PTGS2↓, IL6↓, eff↑, PD-L1↓, *cognitive↓, *Aβ↓, *TAC↑, *SOD↑, *eff↑, *eff↑, ChemoSen↑, tumCV↓, Apoptosis↑, ERK↓, chemoP↑, *GPx↑, *GSTs↑, *GSH↑, *SOD↑, *Catalase↑, *ROS↓, *lipid-P↓, *MDA↓, *Casp3↓, *HO-1↓, cardioP↑, radioP↑,
6077- CHL,    Cancer chemoprevention by dietary chlorophylls: A 12,000-animal dose-dose matrix biomarker and tumor study
- in-vivo, Var, NA
eff↑, chemoP↑,
6083- CHOC,    Preventive Effects of Cocoa and Cocoa Antioxidants in Colon Cancer
- Review, Colon, NA
ROS↓, Inflam↓, TumCP↓, Apoptosis↑, *Dose↝, *BioAv↓, *BioAv↑, GSH↑, GSTs↑, PGE2↓, COX1↑, IL8↓, COX2/PTGS2↓, iNOS↓, NF-kB↓, chemoP↑,
6138- CHr,  Cisplatin,    Chrysin protects against cisplatin-induced colon. toxicity via amelioration of oxidative stress and apoptosis: Probable role of p38MAPK and p53
- in-vivo, Nor, NA
*toxicity↝, eff↑, chemoP↑, *ROS↓, *MAPK↑, *P53↑, GSH↓,
2791- CHr,    Chrysin attenuates progression of ovarian cancer cells by regulating signaling cascades and mitochondrial dysfunction
- in-vitro, Ovarian, OV90
TumCP↓, TumCD↑, ROS↑, Ca+2↑, MMP↓, MAPK↑, PI3K↑, p‑Akt↑, PCNA↓, p‑p70S6↑, p‑ERK↑, p38↑, JNK↑, DNAdam↑, TumCCA↑, chemoP↑,
4764- CoQ10,  VitE,    Auxiliary effect of trolox on coenzyme Q10 restricts angiogenesis and proliferation of retinoblastoma cells via the ERK/Akt pathway
- in-vitro, RPE/RB, Y79 - in-vitro, Nor, ARPE-19 - in-vivo, NA, NA
tumCV↓, Apoptosis↑, ROS↑, MMP↓, TumCCA↑, VEGF↓, ERK↓, Akt↓, ChemoSen↑, chemoP↑, toxicity↓, angioG↓,
4767- CoQ10,    Efficacy of Coenzyme Q10 for Improved Tolerability of Cancer Treatments: A Systematic Review
- Review, Var, NA
chemoP↑, cardioP↑, hepatoP↑, eff↝,

Showing Research Papers: 1 to 50 of 228
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 228

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 8,   antiOx⇅, 1,   Bil↝, 1,   Catalase↓, 2,   Catalase↑, 4,   GPx↓, 1,   GPx↑, 2,   GPx4↓, 3,   GSH↓, 15,   GSH↑, 3,   GSH∅, 1,   GSR↓, 1,   GSTs↓, 1,   GSTs↑, 1,   H2O2↑, 1,   i-H2O2↓, 1,   HO-1↓, 3,   HO-1↑, 3,   HO-2↑, 1,   i-Iron↓, 1,   c-Iron↑, 1,   lipid-P↓, 4,   lipid-P↑, 4,   MDA↓, 2,   MDA↑, 1,   NOX4↑, 1,   NQO1↓, 1,   NQO1↑, 1,   Nrf1↑, 1,   NRF2↓, 5,   NRF2↑, 6,   Prx6↑, 1,   PrxI↓, 1,   PrxI∅, 1,   PrxII↑, 1,   PrxII∅, 1,   ROS↓, 11,   ROS↑, 76,   ROS⇅, 6,   ROS↝, 1,   ROS∅, 1,   i-ROS↑, 1,   mt-ROS↑, 3,   SOD↓, 3,   SOD↑, 3,   SOD2↓, 2,   Thiols↓, 1,   Trx↓, 1,   TrxR↑, 1,   uricA↓, 1,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 1,   CDC25↓, 1,   compI↓, 2,   compII↓, 1,   EGF↓, 1,   ETC↓, 2,   Insulin↓, 1,   MKK7↓, 1,   mtDam↓, 1,   mtDam↑, 5,   PGC-1α↑, 1,   SIRT3↓, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   5LO↓, 1,   ACSL4↑, 2,   ALAT↓, 4,   AMP↑, 1,   AMPK↑, 2,   p‑AMT/GCST/T-protein↑, 1,   ATP↓, 4,   BHB↑, 1,   FASN↓, 3,   GLO-I↓, 1,   glucoNG↓, 1,   glucose↝, 1,   GlucoseCon↓, 1,   GlucoseCon∅, 1,   GlutMet↓, 1,   Glycolysis↓, 4,   GSK‐3β↓, 3,   GSK‐3β↑, 5,   p‑GSK‐3β↓, 1,   H2S↑, 1,   HK2↓, 2,   HMG-CoA↓, 1,   HMGCS2↑, 1,   lactateProd∅, 1,   LDHA↓, 3,   lipoGen↓, 1,   NAD↑, 1,   NADPH↓, 1,   PCK1↓, 1,   PDK1 / PDPK1↓, 2,   PFK1↓, 1,   PKM2↓, 3,   PPP↓, 1,   SCD1↓, 1,   SIRT1↓, 2,   SIRT1↑, 2,   SREBP1/SREBF1↓, 1,   TCA↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 4,   APAF1↑, 3,   Apoptosis?, 1,   Apoptosis↓, 4,   Apoptosis↑, 61,   m-Apoptosis↑, 1,   ASC↓, 1,   BAD↓, 1,   BAD↑, 1,   Bak↑, 2,   BAX↓, 1,   BAX↑, 29,   Bax:Bcl2↑, 3,   Bcl-2↓, 31,   Bcl-2↑, 1,   Bcl-xL↓, 8,   BIM↓, 1,   BIM↑, 1,   Casp↑, 19,   Casp1↓, 1,   Casp12↑, 1,   Casp3↑, 30,   cl‑Casp3↑, 3,   proCasp3↑, 1,   Casp7↑, 4,   cl‑Casp7↑, 2,   Casp8↑, 7,   proCasp8↑, 1,   Casp9↓, 2,   Casp9↑, 17,   cl‑Casp9↑, 3,   proCasp9↑, 1,   cFLIP↓, 1,   Cyt‑c↑, 21,   Cyt‑c↝, 1,   Diablo↑, 2,   DR5↑, 5,   Fas↓, 1,   Fas↑, 5,   FasL↓, 1,   FasL↑, 1,   Ferroptosis↑, 5,   GSDMD↑, 1,   IAP1↓, 4,   IAP2/BIRC3↓, 4,   iNOS↓, 6,   Mcl-1↓, 6,   p‑MDM2↓, 1,   MOMP↑, 1,   p38↓, 1,   p38↑, 6,   p‑p38↓, 3,   p‑p38↑, 2,   Pyro↑, 1,   survivin↓, 15,   TumCD↓, 1,   TumCD↑, 8,   XIAP↓, 7,   YAP/TEAD↓, 1,   YAP/TEAD↝, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 37,   Akt↑, 2,   p‑Akt↓, 7,   p‑Akt↑, 1,   cMET↓, 1,   p‑cMET↑, 1,   cSrc↓, 1,   EGFR↓, 8,   EGFR↑, 1,   p‑EGFR↓, 1,   ERK↓, 21,   p‑ERK↓, 3,   p‑ERK↑, 1,   HCAR2↑, 1,   HER2/EBBR2↓, 1,   HGF/c-Met↓, 2,   IKKα↓, 1,   IκB↓, 1,   JAK↓, 2,   JAK1↓, 2,   JAK2↓, 1,   JNK↓, 2,   JNK↑, 4,   p‑JNK↓, 1,   p‑JNK↑, 3,   MAPK↓, 13,   MAPK↑, 4,   MEK↓, 2,   MKK4↓, 1,   mTOR↓, 15,   p‑mTOR↓, 1,   mTORC2↓, 1,   p42↓, 1,   p‑p70S6↑, 1,   PI3K↓, 30,   PI3K↑, 2,   p‑PI3K↓, 3,   PKCδ↓, 3,   PTEN↓, 1,   PTEN↑, 4,   Raf↓, 2,   e-Raf↓, 1,   RAS↓, 5,   RAS↑, 1,   Sp1/3/4↓, 1,   p‑Src↓, 1,   STAT↓, 2,   STAT3↓, 17,   p‑STAT3↓, 2,   p‑STAT6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   ChrMod↑, 1,   cJun↓, 1,   cJun↑, 1,   cMyc↓, 4,   cMyc↑, 1,   DNMT1↓, 1,   DNMT3B↓, 1,   DNMTs↓, 2,   EZH2↓, 1,   FOXO↑, 2,   FOXO1↑, 1,   H3↓, 1,   p‑H3↓, 1,   H4↓, 1,   HATs↑, 2,   HDAC↓, 10,   HDAC2↓, 1,   HDAC3↓, 1,   miR-106b↓, 1,   miR-124-3p↓, 1,   miR-203↑, 1,   miR-34a↑, 1,   Myc↑, 1,   MYCN↓, 1,   OCT4↓, 2,   other?, 1,   other↑, 2,   other↝, 10,   PhotoS↑, 2,   Prot↓, 1,   sonoS↑, 1,   tumCV↓, 14,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 2,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 5,   eIF2α↑, 2,   p‑eIF2α↑, 1,   ER Stress↑, 7,   GRP78/BiP↑, 3,   GRP94↑, 1,   HSP70/HSPA5↓, 1,   HSP90↓, 2,   IRE1∅, 1,   NQO2↑, 1,   p‑PERK↑, 1,   UPR↑, 3,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 3,   Beclin-1/ATG6↑, 4,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3A↑, 1,   LC3II↑, 5,   LC3s↑, 1,   p62↓, 1,   TumAuto↑, 8,   TumAuto↝, 2,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   DNAdam↓, 1,   DNAdam↑, 18,   DNArepair↓, 1,   ERCC1↓, 1,   P53?, 1,   P53↓, 1,   P53↑, 21,   p‑P53↑, 2,   PARP↑, 5,   cl‑PARP↓, 1,   cl‑PARP↑, 19,   PCNA↓, 10,   Telomerase↓, 3,   TOP1↓, 2,   TOP2↓, 1,   γH2AX↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 2,   CDK1↑, 1,   CDK2↓, 5,   CDK4↓, 9,   CDK6↓, 2,   CDK6↑, 1,   CHK1↓, 1,   CHK1↑, 1,   Chk2↑, 1,   Cyc↓, 1,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 5,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 17,   cycE/CCNE↓, 4,   E2Fs↓, 1,   GADD34↑, 1,   GADD45A↑, 2,   Ki-67↓, 7,   mitA↑, 1,   P21↓, 1,   P21↑, 14,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 5,   pRB↓, 1,   p‑pRB↓, 2,   RB1↑, 1,   TumCCA↓, 2,   TumCCA↑, 53,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   BMPs↑, 1,   CD133↓, 1,   CD34↓, 1,   cFos↑, 1,   CSCs?, 1,   CSCs↓, 9,   Diff↑, 2,   FGF↓, 1,   HH↓, 1,   HH↝, 1,   IGF-1↓, 4,   IGFBP3↑, 1,   Ki-67↓, 7,   LRP6↓, 1,   mTORC1↓, 1,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 2,   NOTCH1↓, 7,   OGFr↑, 3,   SCF↓, 1,   Shh↓, 1,   TumCG↓, 27,   TumCG↑, 1,   TumCP↓, 51,   TumCP↑, 3,   Wnt↓, 11,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   AP-1↓, 2,   AXL↓, 2,   BACH1↓, 1,   CA↓, 1,   Ca+2↓, 1,   Ca+2↑, 9,   Cav1↓, 1,   Cdc42↓, 1,   Cofilin↓, 1,   E-cadherin↓, 2,   E-cadherin↑, 6,   EMT↓, 12,   EpCAM↓, 1,   F-actin↓, 1,   FAK↓, 3,   p‑FAK↓, 2,   fascin↓, 1,   Fibronectin↓, 1,   ITGB1↓, 1,   LAMs↓, 1,   MALAT1↓, 1,   MET↓, 1,   p‑MET↓, 1,   MMP1↓, 1,   MMP13↓, 1,   MMP2↓, 20,   MMP3↓, 2,   MMP7↓, 1,   MMP9↓, 21,   MMPs↓, 12,   N-cadherin↓, 6,   PDGF↓, 2,   Rac1↓, 1,   Rho↓, 2,   ROCK1↓, 1,   Slug↓, 1,   Snail↓, 3,   TGF-β↓, 5,   TGF-β1↓, 1,   TIMP1↑, 5,   TIMP2↑, 2,   TumCI↓, 19,   TumCMig↓, 23,   TumMeta↓, 25,   TumMeta↑, 1,   Twist↓, 3,   Tyro3↓, 1,   uPA↓, 4,   Vim↓, 7,   Vim↑, 1,   Zeb1↓, 2,   β-catenin/ZEB1↓, 13,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 32,   angioG↑, 1,   CD31/PECAM-1↓, 3,   HIF-1↓, 3,   Hif1a↓, 21,   LOX1↓, 1,   VCAM-1↓, 2,   VEGF↓, 30,   VEGFR2/KDR/Flk1↓, 5,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   CellMemb↑, 1,   CLDN1↓, 1,   EPR↑, 2,   GastroP↑, 1,   GLUT1↓, 1,   GLUT2↓, 1,   MMP↓, 30,   NHE1↓, 1,   OATPs↓, 2,   TRPM7↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   CD4+↑, 1,   CD44↓, 2,   CD47↓, 1,   CD8+↑, 3,   COX1↓, 1,   COX1↑, 1,   COX2/PTGS2↓, 26,   CXCR4↓, 6,   DCells↑, 1,   HCAR2↑, 1,   HMGB1↓, 2,   ICAM-1↓, 1,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL1↓, 2,   IL10↓, 2,   IL10↑, 1,   IL12↑, 1,   IL1β↓, 10,   IL2↓, 1,   IL2↑, 4,   IL6↓, 15,   IL8↓, 3,   Imm↑, 16,   Imm↝, 1,   INF-γ↑, 1,   INF-γ↝, 1,   Inflam↓, 19,   Inflam↑, 2,   M2 MC↓, 1,   MDSCs↓, 1,   Neut↑, 2,   NF-kB↓, 45,   NF-kB↑, 1,   p‑NF-kB↑, 1,   NK cell↑, 5,   NLRP3↓, 3,   NLRP3↑, 2,   p65↓, 2,   p‑p65↓, 1,   PD-1↓, 2,   PD-L1↓, 4,   PD-L1↑, 1,   PGE2↓, 7,   PGE2↑, 1,   PSA↓, 5,   T-Cell↑, 1,   Th1 response↑, 1,   Th2↑, 1,   TLR4↓, 1,   TNF-α↓, 18,   TNF-α↑, 2,  

Cellular Microenvironment(tgid=17) ⓘ

TAMS↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

BDNF↓, 1,   TrkB↓, 1,  

Protein Aggregation(tgid=19) ⓘ

PSEN1/PS1↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 2,   CYP19↓, 1,   ER-α36↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 14,   BioAv↑, 18,   BioAv↝, 4,   chemoR↓, 1,   ChemoSen?, 1,   ChemoSen↑, 106,   ChemoSen⇅, 1,   ChemoSen↝, 1,   ChemoSen∅, 2,   CompStab↓, 2,   CYP1A1↓, 3,   CYP1A1↑, 1,   CYP1A2↓, 1,   CYP3A4↓, 1,   Dose?, 2,   Dose↑, 9,   Dose↝, 43,   Dose∅, 1,   eff↓, 8,   eff↑, 32,   eff⇅, 1,   eff↝, 9,   eff∅, 1,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 6,   MDR1↓, 4,   MRP1/ABCC1↓, 2,   P-gp/ABCB1↓, 6,   P450↓, 3,   RadioS↑, 23,   RadioS↝, 1,   selectivity↑, 38,   Synergy↑, 33,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 4,   ALP↓, 1,   AR↓, 2,   AST↓, 2,   Bil↝, 1,   BUN↓, 3,   CEA↓, 1,   creat↓, 3,   EGFR↓, 8,   EGFR↑, 1,   p‑EGFR↓, 1,   EZH2↓, 1,   HemoG↑, 1,   HER2/EBBR2↓, 1,   IL6↓, 15,   LDH↑, 1,   e-LDH↑, 1,   Myc↑, 1,   NSE↓, 1,   PC↑, 1,   PD-L1↓, 4,   PD-L1↑, 1,   PSA↓, 5,   RBC↑, 3,   Verbal↑, 1,   WBC↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 1,   AntiCan↑, 23,   AntiCan∅, 1,   AntiDiabetic↑, 1,   antiNeop↑, 1,   AntiTum↑, 12,   Appetite↑, 2,   BowelM↑, 1,   breath↑, 1,   cachexia↓, 2,   cardioP↑, 10,   chemoP?, 1,   chemoP↓, 3,   chemoP↑, 181,   chemoP↝, 1,   chemoP∅, 1,   chemoPv↑, 5,   ChemoSideEff↓, 4,   cognitive↑, 2,   fatigue↓, 1,   fatigue∅, 1,   hepatoP↑, 17,   hepatoP∅, 1,   memory↑, 1,   Mucositis↓, 1,   Nausea↓, 1,   neuroP↓, 1,   neuroP↑, 7,   NP/CIPN↓, 3,   OS↓, 2,   OS↑, 12,   OS⇅, 1,   Pain↓, 7,   PFS↑, 1,   QoL↑, 20,   QoL∅, 2,   radioP↑, 29,   radioP↝, 1,   Remission↑, 1,   RenoP↑, 9,   RenoP∅, 1,   Risk↓, 19,   Risk↑, 2,   Risk⇅, 1,   Sleep↑, 2,   Strength↑, 2,   toxicity↓, 11,   toxicity↑, 1,   toxicity↝, 4,   toxicity∅, 2,   TumVol?, 1,   TumVol↓, 10,   TumVol↑, 1,   TumW↓, 1,   Weight↑, 5,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   GutMicro↑, 4,   Sepsis↓, 2,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 608

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 60,   ARE↑, 1,   Catalase↑, 24,   Copper↓, 1,   Fenton↓, 2,   GPx↑, 23,   GPx1↑, 1,   GPx4↓, 1,   GPx4↑, 1,   GSH↑, 28,   GSR↑, 4,   GSTs↑, 9,   H2O2↓, 1,   HDL↑, 2,   HO-1↓, 2,   HO-1↑, 21,   Iron↓, 2,   Iron↑, 1,   Keap1↓, 2,   Keap1↝, 1,   lipid-P↓, 18,   MDA↓, 18,   MDA↑, 1,   MPO↓, 6,   MPO↑, 2,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 2,   NQO1↑, 3,   NRF2↑, 39,   RNS↓, 3,   ROS↓, 67,   ROS↝, 1,   ROS∅, 2,   mt-ROS?, 1,   SAM-e↑, 1,   selenoP↑, 2,   SOD↑, 34,   SOD1↑, 3,   SOD2↑, 2,   TAC↑, 1,   TBARS↓, 2,   VitE↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,   compII↑, 1,   compIII↑, 1,   DRP1/DNM1L↓, 1,   FIS1↓, 1,   Insulin↓, 1,   Insulin↑, 1,   MFN2↑, 2,   mtDam↓, 1,   PGC-1α↑, 2,   PGC-1α↝, 1,   PINK1↑, 1,   SIRT3↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

15-LOX/ALOX15↓, 1,   5LO↓, 1,   ACC↓, 1,   Acetyl-CoA↓, 1,   adiP↑, 1,   ALAT↓, 9,   AMPK↑, 5,   ATP↑, 4,   ATP↝, 1,   CRM↓, 1,   FABP4↓, 1,   FASN↓, 1,   FFA/NEFA↓, 1,   glucose↓, 4,   glucose↝, 1,   GlucoseCon↑, 1,   GSK‐3β↑, 1,   H2S↑, 1,   KeyT↝, 1,   LDL↓, 4,   NAD↝, 1,   NADPH↓, 4,   NADPH↑, 1,   PLA2↓, 1,   SIRT1↑, 4,   SREBF2⇅, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   Apoptosis↓, 10,   ASK1↓, 1,   BAX↓, 1,   Bax:Bcl2↓, 1,   Bcl-2↑, 2,   Bcl-xL↑, 1,   Casp12↓, 1,   Casp3↓, 12,   cl‑Casp8↑, 1,   Casp9↓, 5,   Cyt‑c↓, 1,   Fas↓, 1,   FasL↓, 1,   Ferroptosis↓, 2,   GranB/GZMB↓, 1,   iNOS↓, 8,   necrosis↓, 1,   p38↓, 2,   p‑p38↓, 1,   TUNEL↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   Akt↑, 5,   Akt↝, 1,   AMPKα↑, 1,   ERK↓, 2,   IGF-1R↓, 1,   IKKα↑, 1,   IκB?, 1,   JAK↓, 1,   JAK2↑, 1,   JNK↓, 1,   p‑JNK↓, 2,   MAPK↓, 2,   MAPK↑, 1,   MAPK↝, 1,   mTOR↓, 3,   p‑mTOR↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 2,   PI3K↑, 2,   PKCδ?, 1,   PKCδ↓, 1,   PTEN↓, 1,   STAT3↓, 1,   STAT3↑, 1,   STAT3↝, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 4,   ATF2↑, 1,   ATF4↓, 1,   FOXO3↑, 1,   HDAC↑, 1,   miR-34a↓, 1,   other?, 2,   other↓, 5,   other↑, 10,   other↝, 2,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 2,   p‑eIF2α↓, 1,   ER Stress↓, 3,   GRP78/BiP↓, 2,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 1,   MitoP↓, 1,   p62↑, 1,   PARK2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 4,   DNArepair↑, 1,   P53↓, 3,   P53↑, 1,   PARP1↓, 1,   PCNA↑, 1,   SIRT6↑, 1,   Telomerase↓, 1,   TOP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

E2Fs↑, 1,   GADD45A↑, 1,   P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMPs↑, 1,   CEBPA↓, 1,   EP2↓, 1,   HH↓, 1,   IGF-1↑, 1,   mTORC1↓, 1,   neuroG↑, 1,   p300↓, 1,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 2,   AntiAg↑, 5,   AP-1↓, 3,   Ca+2↓, 1,   Ca+2↝, 2,   Cartilage↑, 1,   COL1↓, 1,   E-cadherin↑, 1,   EMT↓, 1,   MMP13↓, 1,   MMP2↓, 1,   MMPs↓, 1,   p‑Rac1↓, 1,   serineP↓, 1,   TGF-β↓, 1,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   uPA↑, 1,   Vim↓, 1,   α-SMA↓, 1,   α-SMA↝, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   Hif1a↑, 1,   NO↓, 5,   VCAM-1↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 5,   BBB∅, 1,   GastroP↑, 1,   GLUT4↑, 1,   H+/K+-ATPase↓, 1,   IBI↑, 1,   memfluid↑, 1,   MMP↑, 5,   TRPM7↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD25+↑, 1,   CD4+↑, 2,   CD8+↑, 1,   COX1↓, 3,   COX2/PTGS2↓, 15,   COX2/PTGS2↑, 1,   FOXP3↑, 1,   HMGB1↓, 2,   IFN-γ↓, 2,   IL10↓, 4,   IL10↑, 5,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 13,   IL2↓, 1,   IL4↓, 3,   IL4↑, 2,   IL6↓, 23,   IL8↓, 2,   Imm↑, 6,   Imm↝, 1,   Inflam↓, 64,   LPS↓, 2,   M2 MC↑, 2,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 3,   MyD88↓, 1,   NF-kB↓, 20,   NLRP3↓, 4,   PGE2↓, 7,   TLR4↓, 3,   TNF-α↓, 27,   Treg lymp↝, 1,   TRIF↓, 1,   VitD↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   5HT↑, 1,   AChE↓, 4,   BChE↓, 2,   BDNF↑, 2,   MAOA↓, 1,   MAOB↓, 1,   NGF↑, 1,   TrkB↑, 1,   β-Endo↑, 1,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 1,   Aβ↓, 2,   BACE/β-secretase↓, 1,   p‑tau↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   ACE2↓, 1,   BNP↓, 1,   NR1H4↑, 1,   PPARγ↓, 1,   testos↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 19,   BioAv↑, 21,   BioAv↝, 14,   BioEnh↑, 2,   ChemoSen↑, 1,   CYP3A2↓, 1,   Dose?, 3,   Dose↓, 2,   Dose↑, 2,   Dose↝, 14,   eff↑, 9,   GSTA1↑, 2,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 8,   P-gp/ABCB1↓, 2,   selectivity↑, 3,   Synergy↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 9,   ALB↝, 1,   ALP↓, 3,   AST↓, 12,   BloodF↑, 1,   BMD↑, 3,   BP↓, 4,   BUN?, 1,   BUN↓, 4,   Calcium↑, 1,   creat↓, 9,   hs-CRP↓, 1,   IL6↓, 23,   IRes↝, 1,   KeyT↝, 1,   LDH↓, 4,   Mag↑, 1,   NOS2↓, 1,   SpO2↑, 1,   TC↓, 1,   TG/TAG↓, 1,   TMAO↓, 1,   Urea↓, 2,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   AntiAge↑, 5,   antiAll↑, 8,   AntiArt↑, 1,   AntiCan↑, 10,   AntiDiabetic↓, 1,   AntiDiabetic↑, 11,   antiPs↑, 2,   AntiTum↓, 1,   AntiTum↑, 3,   cardioP?, 2,   cardioP↑, 25,   chemoP↑, 46,   chemoPv↑, 3,   ChemoSideEff↓, 1,   cognitive↓, 1,   cognitive↑, 11,   cough?, 1,   hepatoP↓, 1,   hepatoP↑, 25,   memory↑, 5,   motorD↑, 1,   Mucositis↓, 1,   neuroP↓, 1,   neuroP↑, 28,   Obesity↓, 8,   OS↑, 4,   Pain↓, 4,   QoL↑, 1,   radioP↑, 8,   RenoP↑, 15,   Risk↓, 1,   SoreThr?, 1,   Strength↑, 1,   Stress↓, 1,   Stroke↓, 5,   toxicity↓, 24,   toxicity↑, 1,   toxicity↝, 9,   toxicity∅, 1,   Weight↓, 1,   Weight↑, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 4,   AntiFungal↑, 3,   AntiViral↑, 5,   Bacteria↓, 8,   Diar↓, 1,   GutMicro↑, 9,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 2,   Ingr↝, 2,  
Total Targets: 360

Scientific Paper Hit Count for: chemoP, ChemoProtective
21 Chemotherapy
14 Cisplatin
11 Silymarin (Milk Thistle) silibinin
10 Hydrogen Gas
9 Selenium
8 doxorubicin
8 Selenite (Sodium)
7 Curcumin
7 Thymoquinone
6 Melatonin
5 Allicin (mainly Garlic)
5 Anti-oxidants
5 Radiotherapy/Radiation
5 phytic acid, Inositol hexakisphosphate
4 Astragalus
4 Quercetin
4 Fucoidan
4 Honokiol
4 Inositol
4 Licorice
4 Luteolin
4 Lycopene
4 Morin
3 Ashwagandha(Withaferin A)
3 Astaxanthin
3 Paclitaxel/Taxol
3 Coenzyme Q10
3 EGCG (Epigallocatechin Gallate)
3 diet Short Term Fasting
3 Dandelion Root
3 HydroxyTyrosol
3 isoorientin
3 Licochalcone A
3 low dose naltrexone
3 Linalool
3 Magnetic Fields
3 Urolithin
2 Alpha-Lipoic-Acid
2 Apigenin (mainly Parsley)
2 beta-glucans
2 Brucea javanica
2 brusatol
2 Boron
2 Butyrate
2 Propolis -bee glue
2 Carvacrol
2 Thymol-Thymus vulgaris
2 Chrysin
2 Garcinol
2 Docosahexaenoic Acid
2 Ellagic acid
2 Fisetin
2 Flaxseed/Linseed
2 Shilajit/Fulvic Acid
2 iodine
2 5-fluorouracil
2 Metformin
2 Oleuropein
2 Rosmarinic acid
2 Rutin
2 Selenium NanoParticles
1 Silver-NanoParticles
1 Anzaroot, Astragalus fasciculifolius Bioss
1 Anethole/trans-Anethole
1 Atorvastatin
1 immunotherapy
1 Baicalein
1 Berberine
1 Gold NanoParticles
1 Beta-Caryophyllene
1 Betulinic acid
1 Bromelain
1 α-Bisabolol / Chamomile oil
1 Carnosic acid
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Cat’s Claw
1 Chlorogenic acid
1 Chlorophyllin
1 Chocolate
1 Vitamin E
1 Calorie Restriction Mimetics
1 HydroxyCitric Acid
1 Crocetin
1 diet Plant based
1 Diindolylmethane
1 Indole-3-carbinol
1 Lemongrass Extract/Citral
1 Disulfiram
1 Copper and Cu NanoParticles
1 Echinacea
1 Docetaxel
1 Emodin
1 Eugenol
1 Exercise
1 Formononetin
1 carboplatin
1 Gallic acid
1 Ginkgetin
1 γ-linolenic acid (Borage Oil)
1 Hyperoside
1 MCT, metronomic chemo
1 Isoliquiritigenin
1 isoflavones
1 isoquercitrin
1 Kaempferol
1 Lactoferrin/Talactoferrin
1 SDG/lignans
1 Magnolol
1 Matrine
1 Magnetic Field Rotating
1 Moringa oleifera
1 Methylsulfonylmethane
1 Naringin
1 Aidi injection
1 Phenylbutyrate
1 Phenethyl isothiocyanate
1 Piperine
1 Psoralidin
1 benzo(a)pyrene
1 buckwheat sprouts
1 irinotecan
1 Sulforaphane (mainly Broccoli)
1 Shikonin
1 Squalene
1 Vitexin
1 Isovitexin
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1171  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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