RenoP Cancer Research Results

RenoP, K,Renoprotection/Nephroprotective: Click to Expand ⟱
Source:
Type:
Protects kidneys
-Same as nephroprotective
Opposite is : Nephrotoxicity is toxicity in the kidneys


Scientific Papers found: Click to Expand⟱
7980- AAS/EEAA,    Protective Effects of Annona Atemoya Extracts on Inflammation, Oxidative Stress, and Renal Function in Cadmium-Induced Nephrotoxicity in Wistar Rats
- in-vivo, Nor, NA
*creat↓, *SOD↑, *Catalase↑, *GPx↑, *TNF-α↓, *IL6↓, *RenoP↑, *Inflam↓, *ROS↓,
5428- AG,    Meta-Analysis of Astragalus-Containing Traditional Chinese Medicine Combined With Chemotherapy for Colorectal Cancer: Efficacy and Safety to Tumor Response
- Review, CRC, NA
ChemoSen↑, chemoP↑, QoL↑, RenoP∅, hepatoP∅,
2207- AgNPs,  TQ,    Protective effects of Nigella sativa L. seeds aqueous extract-based silver nanoparticles on sepsis-induced damages in rats
- in-vivo, Nor, NA
*eff↑, *RenoP↑, *hepatoP↑, *MDA↓, *SOD↑, *GSH↑, *TNF-α↓, *IL1β↓,
2205- AgNPs,    Potential protective efficacy of biogenic silver nanoparticles synthesised from earthworm extract in a septic mice model
- in-vivo, Nor, NA
*Dose↝, *eff↑, *RenoP↑, *antiOx↑, *MDA↓, *NO↓, *hepatoP↑, *toxicity↝, *GSH↑, *SOD↑, *GSTs↑, *Catalase↑,
5355- AL,    Mini-review: The health benefits and applications of allicin
- Review, Var, NA
*BioAv↑, *cardioP↑, *hepatoP↑, *RenoP↑, *Half-Life↝, *BioAv↓, *neuroP↑, *cognitive↑, *ROS↓, *lipid-P↓, *DNArepair↑, *ChemoSen↑,
2770- AL,    Allicin protects against renal ischemia–reperfusion injury by attenuating oxidative stress and apoptosis
- in-vivo, Nor, NA - in-vitro, Nor, NRK52E
*antiOx↑, *RenoP↑, *MDA↓, *SOD↑,
3456- ALA,    Renal-Protective Roles of Lipoic Acid in Kidney Disease
- Review, Nor, NA
*RenoP↑, *ROS↓, *antiOx↑, *Inflam↓, *Sepsis↓, *IronCh↑, *BUN↓, *creat↓, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *chemoP↑, *eff↑, *NF-kB↓,
3541- ALA,    Insights on alpha lipoic and dihydrolipoic acids as promising scavengers of oxidative stress and possible chelators in mercury toxicology
- Review, Var, NA
*antiOx↑, *IronCh↑, *GSH↑, *BBB↑, Apoptosis↑, MMP↓, ROS↑, lipid-P↑, PARP1↑, Casp3↑, Casp9↑, *NRF2↑, *GSH↑, *ROS↓, RenoP↑, ChemoSen↑, *BG↓,
7403- Amla,    Aqueous Extract of Emblica officinalis Linn (Indian gooseberry) in Combination with Iodine is More Efficacious than Iodine Alone in Mitigating Mucositis in Head and Neck Cancer Patients Undergoing Curative Radiotherapy: Retrospective Observations
- Trial, HNSCC, NA
Mucositis↓, Dose↝, Dose↝, *Bacteria↓, *AntiFungal↑, *AntiViral↑, *hepatoP↑, *RenoP↑, *neuroP↑, Dose↝,
1999- Api,  doxoR,    Apigenin ameliorates doxorubicin-induced renal injury via inhibition of oxidative stress and inflammation
- in-vitro, Nor, NRK52E - in-vitro, Nor, MPC5 - in-vitro, BC, 4T1 - in-vivo, NA, NA
neuroP↑, ChemoSen∅, RenoP↑, selectivity↑, chemoP↑, ROS↑, *ROS∅, *antiOx↑, *toxicity↓,
3689- Ash,    Ashwagandha attenuates TNF-α- and LPS-induced NF-κB activation and CCL2 and CCL5 gene expression in NRK-52E cells
- in-vitro, Nor, NRK52E
*RenoP↑, *NF-kB↓, *MCP1/CCL2↓, *RANTES↓,
3160- Ash,    Withaferin A: A Pleiotropic Anticancer Agent from the Indian Medicinal Plant Withania somnifera (L.) Dunal
- Review, Var, NA
TumCCA↑, H3↑, P21↑, cycA1/CCNA1↓, CycB/CCNB1↓, cycE/CCNE↓, CDC2↓, CHK1↓, Chk2↓, p38↑, MAPK↑, E6↓, E7↓, P53↑, Akt↓, FOXO3↑, ROS↑, γH2AX↑, MMP↓, mitResp↓, Synergy↑, TumCD↑, Mcl-1↓, ER Stress↑, ATF4↑, ATF3↑, CHOP/DDIT3↑, NOTCH↓, NF-kB↓, Bcl-2↓, STAT3↓, CDK1↓, β-catenin/ZEB1↓, N-cadherin↓, EMT↓, Cyt‑c↑, Synergy↑, CDK4↓, p‑RB1↓, PARP↑, cl‑Casp3↑, cl‑Casp9↑, NRF2↑, ER-α36↓, LDHA↓, lipid-P↑, AP-1↓, COX2/PTGS2↓, RenoP↑, PDGFR-BB↓, SIRT3↑, MMP2↓, MMP9↓, NADPH↑, NQO1↑, GSR↑, HO-1↑, *SOD2↑, *Prx↑, *Casp3?, Synergy↑, Snail↓, Slug↓, Vim↓, CSCs↓, HEY1↓, MMPs↓, VEGF↓, uPA↓, *toxicity↓, CDK2↓, CDK4↓, HSP90↓,
3170- Ash,    Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms
- in-vitro, Nor, NRK52E - in-vivo, NA, NA
*RenoP↑, *hepatoP↑, *creat↓, *BUN↓, *uricA↓, *Apoptosis↓, *α-SMA↓,
5384- AsP,  MLT,    Synergistic Anticancer Effect of Melatonin and Ascorbyl Palmitate Nanoformulation: A Promising Combination for Cancer Therapy
- in-vivo, Var, NA
AntiCan↑, TumCG↓, Apoptosis↑, DNAdam↑, TumCCA↑, IL6↓, STAT3↓, TumCP↓, Ki-67↓, TumCI↓, TumMeta↓, MMP9↓, eff↑, *Catalase↑, *SOD↑, *GSH↑, *MDA↓, *NO↓, *antiOx↑, *hepatoP↑, *RenoP↑,
2629- Ba,    Baicalein, a Component of Scutellaria baicalensis, Attenuates Kidney Injury Induced by Myocardial Ischemia and Reperfusion
- in-vivo, Nor, NA
*RenoP↑, *Apoptosis↓, *TNF-α↓, *IL1↓, *Bcl-2↑, *BAX↓, *Akt↑,
2630- Ba,    Baicalein decreases uric acid and prevents hyperuricemic nephropathy in mice
- in-vivo, Nor, NA
*RenoP↑, *uricA↓, *ROS↓, EMT↓,
2628- Ba,  Cisplatin,    Baicalein alleviates cisplatin-induced acute kidney injury by inhibiting ALOX12-dependent ferroptosis
- in-vitro, Nor, HK-2
*RenoP↑, *12LOX↓, *Ferroptosis↓,
2627- Ba,  Cisplatin,    Baicalein, a Bioflavonoid, Prevents Cisplatin-Induced Acute Kidney Injury by Up-Regulating Antioxidant Defenses and Down-Regulating the MAPKs and NF-κB Pathways
- in-vivo, Var, NA
RenoP↑, *iNOS↑, *TNF-α↓, *IL6↓, *NF-kB↓, *MAPK↓, *ERK↓, *JNK↓, *antiOx↑, *NRF2↓, *HO-1↑, *Cyt‑c∅, *Casp3∅, *Casp9∅, *PARP∅,
2626- Ba,    Molecular targets and therapeutic potential of baicalein: a review
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
AntiCan↓, *neuroP↑, *cardioP↑, *hepatoP↑, *RenoP↑, TumCCA↑, CDK4↓, cycD1/CCND1↓, cycE/CCNE↑, BAX↑, Bcl-2↓, VEGF↓, Hif1a↓, cMyc↓, NF-kB↓, ROS↑, BNIP3↑, *neuroP↑, *cognitive↑, *NO↓, *iNOS↓, *COX2/PTGS2↓, *PGE2↓, *NRF2↑, *p‑AMPK↑, *Ferroptosis↓, *lipid-P↓, *ALAT↓, *AST↓, *Fas↓, *BAX↓, *Apoptosis↓,
2701- BBR,    Berberine Inhibits KLF4 Promoter Methylation and Ferroptosis to Ameliorate Diabetic Nephropathy in Mice
- in-vivo, Diabetic, NA
*Inflam↓, *antiOx↑, *Ferroptosis↓, *RenoP↑, *DNMT1↓, *DNMTs↓, *KLF4↑,
2674- BBR,    Berberine: A novel therapeutic strategy for cancer
- Review, Var, NA - Review, IBD, NA
Inflam↓, AntiCan↑, Apoptosis↑, TumAuto↑, TumCCA↑, TumMeta↓, TumCI↓, eff↑, eff↑, CD4+↓, TNF-α↓, IL1↓, BioAv↓, BioAv↓, other↓, AMPK↑, MAPK↓, NF-kB↓, IL6↓, MCP1/CCL2↓, PGE2↓, COX2/PTGS2↓, *ROS↓, *antiOx↑, *GPx↑, *Catalase↑, AntiTum↑, TumCP↓, angioG↓, Fas↑, FasL↑, ROS↑, ATM↑, P53↑, RB1↑, Casp9↑, Casp8↑, Casp3↓, BAX↑, Bcl-2↓, Bcl-xL↓, IAP1↓, XIAP↓, survivin↓, MMP2↓, MMP9↓, CycB/CCNB1↓, CDC25↓, CDC25↓, Cyt‑c↑, MMP↓, RenoP↑, mTOR↓, MDM2↓, LC3II↑, ERK↓, COX2/PTGS2↓, MMP3↓, TGF-β↓, EMT↑, ROCK1↓, FAK↓, RAS↓, Rho↓, NF-kB↓, uPA↓, MMP1↓, MMP13↓, ChemoSen↑,
2675- BBR,    The therapeutic effects of berberine against different diseases: A review on the involvement of the endoplasmic reticulum stress
- Review, Var, NA
*Inflam↓, *antiOx↑, *ER Stress↓, *cardioP↑, *RenoP↑, *hepatoP↑,
3754- BBR,  CUR,  EGCG,  Hup,    Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer’s disease: A review
- Review, AD, NA
*AChE↓, *Aβ↓, *LDL↓, *RenoP↑, *BChE↓, *eff↑, *BACE/β-secretase↓, *AChE↓, *Synergy↑,
2725- BetA,    Betulinic acid protects against renal damage by attenuation of oxidative stress and inflammation via Nrf2 signaling pathway in T-2 toxin-induced mice
- in-vivo, Nor, NA
*RenoP↑, *SOD?, *Catalase↑, *GSH↑, *ROS↓, *MDA↓, *IL1β↓, *TNF-α↓, *IL10↓, *IL6↑, *NRF2↑,
2760- BetA,    A Review on Preparation of Betulinic Acid and Its Biological Activities
- Review, Var, NA - Review, Stroke, NA
AntiTum↑, Cyt‑c↑, Smad1↑, Sepsis↓, NF-kB↓, ICAM-1↓, MCP1/CCL2↓, MMP9↓, COX2/PTGS2↓, PGE2↓, ERK↓, p‑Akt↓, *ROS↓, *LDH↓, *hepatoP↑, *SOD↑, *Catalase↑, *GSH↑, *AST↓, *ALAT↓, *RenoP↑, *ROS↓, *α-SMA↓,
730- Bor,  Cisplatin,    The Effect of Boric Acid and Borax on Oxidative Stress, Inflammation, ER Stress and Apoptosis in Cisplatin Toxication and Nephrotoxicity Developing as a Result of Toxication
- in-vivo, Var, NA
*ROS↓, *Inflam↓, RenoP↑,
3502- Bor,    Plasma boron concentrations in the general population: a cross-sectional analysis of cardio-metabolic and dietary correlates
- Review, CardioV, NA
*Half-Life↑, *VitD↑, *cardioP↑, *RenoP↓,
3510- Bor,    Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks
- in-vivo, Nor, NA
*RenoP↑, *ROS↓, *antiOx↑, *Apoptosis↓, *NRF2↑, *HO-1↑, *MDA↓, *lipid-P↓, *GPx↓, *Catalase↑, *SOD↑, *ALAT↓, *AST↓, *ALP↓,
6542- BSB,    Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol
- Review, Var, NA - Review, Park, NA - Review, AD, NA
AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2/PTGS2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE/β-secretase↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2/PTGS2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL6↑, *MMP13↓,
8182- BSO,  LEC,    The Protecting Role of Black Seed Oil and Its Nano-Formulation in LPS-Induced Acute Kidney Injury in Mice: Evaluation of Oxidative Stress, Biochemical & Molecular Parameters
- in-vivo, Nor, NA
*Inflam↓, *ROS↓, *RenoP↑, *Dose↝,
5834- CAP,    Capsaicin and TRPV1: A Novel Therapeutic Approach to Mitigate Vascular Aging
- Study, Nor, NA
*AntiCan↑, *Inflam↓, *antiOx↑, *TRPV1↑, *AMPK↑, *SIRT1↑, *NADPH↓, *ROS↓, *MAPK↓, *eNOS↑, *Wnt/(β-catenin)↓, RenoP↑,
5830- CAP,    Inhibition of pyroptosis and apoptosis by capsaicin protects against LPS-induced acute kidney injury through TRPV1/UCP2 axis in vitro
- in-vitro, Nor, HK-2
*IL1β↓, *IL18↓, *TRPV1↑, *ROS↓, *MMP↑, *Apoptosis↓, *RenoP↑, *Inflam↓, *UCPs↑,
2017- CAP,    Spice Up Your Kidney: A Review on the Effects of Capsaicin in Renal Physiology and Disease
- Review, Var, NA
RenoP↑, AntiTum↑, AMPK↑, mTOR↑, PD-1↓, PD-L1↓,
5881- CAR,    Carvacrol—A Natural Phenolic Compound with Antimicrobial Properties
- Review, Nor, NA
*Bacteria↓, *Inflam↓, *SOD↑, *GPx↑, *GSR↑, *Catalase↑, *toxicity↓, *Pain↓, *other↑, *cardioP↑, *RenoP↑, *neuroP↑, *antiOx↑, *AntiDiabetic↑, *hepatoP↑, *Obesity↓, *AntiAg↑, *BioAv↓, BioAv↝, *OS↑, MMP↓, ROS↑, *MDA↓, *lipid-P↓, *COX2/PTGS2↓, *Dose↝,
5898- CAR,    Carvacrol-induced apoptosis via tumor suppressor gene activation and oxidative stress modulation in a rat model of breast cancer
- in-vivo, BC, NA
*lipid-P↓, *MDA↓, *antiOx↑, *Inflam↑, RenoP↑, hepatoP↑, *ALAT↓, AST↓, creat↓, chemoPv↑, Cyt‑c↑, FADD↑, P53↑,
6010- CGA,    The Biological Activity Mechanism of Chlorogenic Acid and Its Applications in Food Industry: A Review
- Review, Nor, NA
*antiOx↑, *hepatoP↑, *RenoP↑, AntiTum↑, *glucose↝, *Inflam↓, *neuroP↑, *ROS↓, *Keap1↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *MDA↓, *p‑ERK↑, *GRP78/BiP↑, *CHOP/DDIT3↑, *GRP94↑, *Casp3↓, *Casp9↓, *HGF/c-Met↑, *TNF-α↓, *TLR4↓, *MAPK↓, *IL1β↓, *iNOS↓, TCA↓, Glycolysis↓, Bcl-2↓, BAX↑, MAPK↑, JNK↑, CSCs↓, Nanog↓, SOX2↓, CD44↓, OCT4↓, P53↑, P21↑, *SOD1↑, *AGEs↓, *GLUT2↑, *HDL↑, *Fas↓, *HMG-CoA↓, *NF-kB↓, *HO-1↓, *COX2/PTGS2↓, *TLR4↓, *BioAv↑, *BioAv↝, TumCP↓, TumCMig↓, TumCI↓,
6023- CGA,    Pharmacological advances of the chlorogenic acids family: current insights and future research directions
- Review, AD, NA - Review, Park, NA - Review, IBD, NA
*Aβ↓, *neuroP↑, *cardioP↑, *GastroP↑, *RenoP↑, *hepatoP↑, *Obesity↓, *Bacteria↓, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *GutMicro↑, *IBI↑, *MCT1↓, *NF-kB↓, *DNMT1↓,
6135- CHr,    Chrysin as a Multifunctional Therapeutic Flavonoid: Emerging Insights in Pathogenesis Management: A Narrative Review
- Review, Var, NA - Review, AD, NA
Inflam↓, angioG↓, Apoptosis↑, TumAuto↑, TumCCA↑, BioAv↓, Half-Life↓, BioAv↓, *ROS↓, *hepatoP↑, *RenoP↑, TET1↑, MMP9↓, cMyc↓, Ki-67↓, CBR1↓, ROS↑, ChemoSen↑, Bax:Bcl2↑, PUMA↑, NOTCH1↑, *AntiDiabetic↑, *neuroP↑, *GABA↑, *DNAdam↓, *BDNF↑, *memory↑, *AGEs↓, *Aβ↓, *cardioP↑, *AntiArt↑, Synergy↑, Synergy↑, *Synergy↑, RadioS↑, Synergy↑, ChemoSen↑, eff↑,
2782- CHr,    Broad-Spectrum Preclinical Antitumor Activity of Chrysin: Current Trends and Future Perspectives
- Review, Var, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *Inflam↓, *hepatoP↑, *neuroP↑, *BioAv↓, *cardioP↑, *lipidLev↓, *RenoP↑, *TNF-α↓, *IL2↓, *PI3K↓, *Akt↓, *ROS↓, *cognitive↑, Synergy↑, cycD1/CCND1↓, hTERT/TERT↓, VEGF↓, p‑STAT3↓, TumMeta↓, TumCP↓, Synergy↑, Synergy↑, IL1β↓, IL6↓, NF-kB↓, ROS↑, MMP↓, Cyt‑c↑, Apoptosis↑, ER Stress↑, Ca+2↑, TET1↑, Let-7↑, Twist↓, EMT↓, TumCCA↑, Casp3↑, Casp9↑, BAX↑, HK2↓, GlucoseCon↓, lactateProd↓, Glycolysis↓, SHP1↑, N-cadherin↓, E-cadherin↑, UPR↑, PERK↑, ATF4↑, eIF2α↑, RadioS↑, NOTCH1↑, NRF2↓, BioAv↑, Synergy↑,
2785- CHr,    Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin
- Review, Var, NA
*NF-kB↓, *COX2/PTGS2↓, *iNOS↓, angioG↓, TOP1↓, HDAC↓, TNF-α↓, IL1β↓, cardioP↑, RenoP↑, neuroP↑, LDL↓, BioAv↑, Synergy↑, cycD1/CCND1↓, hTERT/TERT↓, MMP-10↓, Akt↓, STAT3↓, VEGF↓, EGFR↓, Snail↓, Slug↓, Vim↓, E-cadherin↑, Synergy↑, TET1↑, ROS↑, mTOR↓, PPARα↓, ER Stress↑, Ca+2↑, ERK↓, MMP↑, Cyt‑c↑, Casp3↑, HK2↓, NRF2↓, HO-1↓, MMP2↓, MMP9↓, Fibronectin↓, GRP78/BiP↑, XBP-1↓, p‑eIF2α↑, *AST↓, ALAT↓, ALP↓, LDH↓, COX2/PTGS2↑, Bcl-xL↓, IL6↓, PGE2↓, iNOS↓, DNAdam↑, UPR↑, Hif1a↓, EMT↓, Twist↓, lipid-P↑, CLDN1↓, PDK1 / PDPK1↓, IL10↓, TLR4↓, NOTCH1↑, PARP↑, Mcl-1↓, XIAP↓,
2788- CHr,    Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action
- Review, Var, NA
*neuroP↑, *Inflam↓, *ROS↓, NF-kB↓, *PCNA↓, *COX2/PTGS2↓, ChemoSen↑, Hif1a↓, angioG↓, *chemoPv↑, PDGF↓, *memory↑, *RenoP↑, *PPARα↑, *lipidLev↓, *hepatoP↑, *cardioP⇅, *BioAv↓,
3994- CoQ10,  Se,    Coenzyme Q10 Supplementation in Aging and Disease
- Review, AD, NA - Review, Park, NA
*AntiAge↑, *cardioP↑, *Inflam↓, *antiOx↑, *lipid-P↓, *QoL↑, *neuroP↑, *Dose↝, *BP↓, *IGF-1↑, *IGFBP1↑, *Synergy↑, *LDL↓, *HDL↑, *Synergy↑, *other↑, *RenoP↑, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *other∅,
6293- Cro,    Crocetin: an agent derived from saffron for prevention and therapy for cancer
- Review, Var, NA
*toxicity↓, *lipid-P↓, *neuroP↑, *BloodF↑, *BP↓, *RenoP↑, *ATP↑, AntiCan↑, TumCP↓, Apoptosis↑, lipid-P↓, ROS↓, GSTs↑, Catalase↑, SOD↑,
6194- Cuc,    Pharmacokinetics of cucurbitacin B from Trichosanthes cucumerina L. in rats
- in-vivo, Nor, NA
*BioAv↓, *Half-Life↝, *AST∅, *ALAT∅, *RenoP↝, *Half-Life↝,
6282- DL,    Limonene Exerts Anti-Inflammatory Effect on LPS-Induced Jejunal Injury in Mice by Inhibiting NF-κB/AP-1 Pathway
- in-vivo, IBD, NA
*RenoP↑, *creat↓, *Inflam↓, *TNF-α↓, *IL1β↓, *COX2/PTGS2↓, *ROS↓, *NRF2↑, *GastroP↑, *TLR4↓, *NF-kB↓, *AP-1↓, *Sepsis↓,
6353- DRE,  Cisplatin,    Insights Into Protective Mechanisms of Dandelion Leaf Extract Against Cisplatin-Induced Nephrotoxicity in Rats: Role of Inhibitory Effect on Inflammatory and Apoptotic Pathways
- in-vivo, Nor, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Cyt‑c↓, *DNAdam↓, *GSH↑, *SOD↑, *ALB↝, *creat↓, *BUN↓, *RenoP↑, *lipid-P↓, *TNF-α↓, *Casp3↓, *Casp9↓, *chemoP↑,
6365- DRE,    AN OVERVIEW OF THERAPEUTIC POTENTIALS OF TARAXACUM OFFICINALE (DANDELION): A TRADITIONALLY VALUABLE HERB WITH A REACH HISTORICAL BACKGROUND
- Review, Var, NA
*Inflam↓, *AntiTum↑, *Imm↑, *antiOx↑, *AntiDiabetic↑, *diuretic↑, *RenoP↑, *hepatoP↑, *neuroP↑, AntiTum↑, TNF-α↑, IL1β↑, Apoptosis↑, MMP2↓, MMP9↑, Synergy↑, Diff↑, *ROS↓, *HO-1↑, *NRF2↑, *lipid-P↓,
6621- Ech,  Cisplatin,    Experimental Evaluation of Protective Activity of Echinacea pallida against Cisplatin Toxicity
- in-vivo, Nor, NA
chemoP↑, RenoP↑,
3225- EGCG,    Epigallocatechin‐3‐Gallate Ameliorates Diabetic Kidney Disease by Inhibiting the TXNIP/NLRP3/IL‐1β Signaling Pathway
- in-vitro, Nor, NA - in-vivo, Nor, NA
*RenoP↑, *NLRP3↓, *TXNIP↓, *ASC↓, *Casp1↓, *IL1β↓, *ROS↓, *TNF-α↓, *IL6↓, *IL18↓,
6825- EMD,    Advances in the pharmacological effects and molecular mechanisms of emodin in the treatment of metabolic diseases
- Review, Nor, NA
*Inflam↓, *AntiTum↑, *Bacteria↓, *Imm↑, *glucose↓, *RenoP↑, *TLR4↓, *MyD88↓, *NLRP3↓, *NF-kB↓, *PI3K↓, *mTOR↓, *GSK‐3β↓, *Hif1a↓, *VEGF↓, *GutMicro↑, *Obesity↓, *AntiDiabetic↑, *AMPK↑, *PPARγ↑, *PPARγ↓, *toxicity↝, *hepatoP↑, *AST↓, *ALAT↓,

Showing Research Papers: 1 to 50 of 134
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 134

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase↓, 2,   Catalase↑, 2,   GSH↓, 4,   GSH↑, 1,   GSR↑, 1,   GSTs↑, 1,   H2O2↑, 1,   HO-1↓, 1,   HO-1↑, 1,   lipid-P↓, 1,   lipid-P↑, 4,   MDA↓, 1,   MDA↑, 1,   NQO1↑, 1,   NRF2↓, 2,   NRF2↑, 2,   ROS↓, 5,   ROS↑, 23,   i-ROS↑, 1,   mt-ROS↑, 1,   SOD↓, 2,   SOD↑, 2,   TAC↓, 1,   uricA↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,   IronCh∅, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 2,   CDC25↓, 4,   compI↓, 1,   compII↓, 1,   ETC↓, 1,   mitResp↓, 1,   mtDam↑, 1,   mt-OXPHOS↓, 1,   PGC-1α↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 3,   AMPK↑, 3,   ATP↓, 2,   BHB↑, 1,   GlucoseCon↓, 2,   Glycolysis↓, 4,   GSK‐3β↑, 3,   p‑GSK‐3β↓, 1,   HK2↓, 3,   HMGCS2↑, 1,   lactateProd↓, 1,   LDHA↓, 1,   LDL↓, 1,   NADPH↑, 1,   PCK1↓, 1,   PDK1 / PDPK1↓, 2,   PKM2↓, 1,   SCD1↓, 1,   SIRT1↑, 1,   TCA↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 2,   APAF1↑, 1,   Apoptosis?, 2,   Apoptosis↑, 21,   BAD↑, 1,   Bak↓, 1,   Bak↑, 2,   BAX↓, 1,   BAX↑, 15,   Bax:Bcl2↓, 1,   Bax:Bcl2↑, 3,   Bcl-2↓, 15,   Bcl-xL↓, 4,   BID↑, 1,   BNIP3↑, 2,   Casp↑, 1,   Casp3↓, 1,   Casp3↑, 10,   cl‑Casp3↑, 3,   cl‑Casp7↑, 1,   Casp8↑, 7,   Casp9↑, 7,   cl‑Casp9↑, 4,   cFLIP↓, 1,   Cyt‑c↑, 12,   Diablo↑, 1,   DR5↑, 4,   FADD↑, 1,   Fas↑, 4,   FasL↑, 1,   HEY1↓, 1,   IAP1↓, 1,   IAP2/BIRC3↓, 2,   iNOS↓, 2,   Mcl-1↓, 2,   MDM2↓, 1,   p38↑, 1,   p‑p38↓, 1,   PUMA↑, 1,   survivin↓, 3,   TumCD↑, 2,   XIAP↓, 5,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 18,   Akt↑, 1,   p‑Akt↓, 3,   cMET↓, 1,   p‑cMET↑, 1,   EGFR↓, 3,   EGFR↑, 1,   ERK↓, 7,   p‑ERK↓, 1,   HER2/EBBR2↓, 2,   JAK1↓, 1,   JNK↑, 1,   LIMK1↓, 1,   MAPK↓, 5,   MAPK↑, 2,   mTOR↓, 6,   mTOR↑, 1,   mTORC2↓, 2,   P70S6K↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 10,   p‑PI3K↓, 2,   PKCδ↓, 1,   PTEN↑, 1,   RAS↓, 2,   RAS↑, 1,   SHP1↑, 1,   STAT↓, 1,   STAT3↓, 6,   p‑STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↑, 1,   ATF4↑, 2,   cMyc↓, 5,   DNMT1↓, 3,   DNMT3A↓, 1,   EZH2↓, 1,   FOXO3↑, 1,   H3↑, 1,   p‑H3↓, 1,   HDAC↓, 5,   HDAC1↓, 1,   HDAC4↓, 1,   miR-124-3p↓, 1,   miR-34a↓, 1,   miR-34a↑, 1,   MYCN↓, 1,   OCT4↓, 1,   other↓, 1,   other↑, 1,   SOX2↓, 1,   tumCV?, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 4,   eIF2α↑, 2,   p‑eIF2α↑, 1,   ER Stress↑, 5,   GRP78/BiP↑, 2,   HSP90↓, 1,   PERK↑, 1,   p‑PERK↑, 1,   UPR↑, 2,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   Beclin-1/ATG6↑, 2,   LC3II↑, 3,   LC3s↑, 1,   TumAuto↑, 5,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 2,   BRCA1↑, 1,   DNAdam↑, 7,   hTERT/TERT↓, 2,   P53↑, 10,   PARP↑, 4,   cl‑PARP↑, 4,   PARP1↑, 1,   PCNA↓, 4,   TOP1↓, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 3,   CDK1↑, 1,   CDK2↓, 3,   CDK4↓, 6,   CDK6↑, 1,   CHK1↓, 1,   CHK1↑, 1,   Chk2↓, 1,   Chk2↑, 1,   cycA1/CCNA1↓, 2,   CycB/CCNB1↓, 4,   cycD1/CCND1↓, 7,   cycE/CCNE↓, 1,   cycE/CCNE↑, 1,   GADD45A↑, 2,   Ki-67↓, 4,   P21↓, 1,   P21↑, 8,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 3,   p‑pRB↓, 1,   RB1↑, 1,   p‑RB1↓, 1,   TumCCA↑, 20,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP7/OP1↓, 1,   BMPs↑, 1,   CD133↓, 1,   CSCs?, 1,   CSCs↓, 2,   Diff↑, 2,   FGF↓, 1,   HH↓, 1,   Ki-67↓, 4,   Let-7↑, 1,   mTORC1↓, 2,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 1,   NOTCH1↑, 3,   Shh↓, 1,   TumCG↓, 4,   TumCP↓, 18,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

AP-1↓, 2,   Ca+2↑, 6,   E-cadherin↓, 1,   E-cadherin↑, 3,   EMT↓, 8,   EMT↑, 1,   FAK↓, 2,   Fibronectin↓, 1,   LRP1↓, 1,   MALAT1↓, 1,   MMP-10↓, 1,   MMP1↓, 1,   MMP13↓, 2,   MMP2↓, 7,   MMP3↓, 1,   MMP7↓, 1,   MMP9↓, 8,   MMP9↑, 1,   MMPs↓, 5,   MTA1↓, 1,   MUC4↓, 1,   N-cadherin↓, 2,   PDGF↓, 1,   Rho↓, 3,   ROCK1↓, 1,   Slug↓, 2,   Smad1↑, 1,   Snail↓, 2,   TET1↑, 3,   TGF-β↓, 1,   TIMP2↓, 1,   TIMP2↑, 1,   TumCI↓, 7,   TumCMig↓, 7,   TumMeta↓, 5,   Twist↓, 5,   uPA↓, 4,   Vim↓, 2,   Zeb1↓, 1,   β-catenin/ZEB1↓, 5,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 12,   HIF-1↑, 1,   Hif1a↓, 8,   TBXAS1/TxAS↓, 1,   VEGF↓, 12,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

CLDN1↓, 1,   GLUT1↓, 1,   MMP↓, 11,   MMP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↓, 1,   CD44↓, 1,   CD47↓, 1,   CD8+↑, 2,   COX2/PTGS2↓, 9,   COX2/PTGS2↑, 1,   CXCR4↓, 1,   DR4↑, 1,   HMGB1↓, 1,   ICAM-1↓, 1,   IL1↓, 1,   IL10↓, 1,   IL1β↓, 4,   IL1β↑, 1,   IL6↓, 5,   IL8↓, 1,   Imm↑, 2,   INF-γ↝, 1,   Inflam↓, 4,   MCP1/CCL2↓, 2,   Neut↑, 1,   NF-kB↓, 21,   NF-kB↑, 1,   NK cell↑, 1,   NLRP3↓, 1,   PD-1↓, 1,   PD-L1↓, 3,   PGE2↓, 5,   PSA↓, 1,   T-Cell↑, 1,   TLR4↓, 3,   TNF-α↓, 6,   TNF-α↑, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ER-α36↓, 1,   PPARα↓, 1,   PPARγ↝, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 4,   BioAv↑, 4,   BioAv↝, 1,   CBR1↓, 1,   ChemoSen↓, 1,   ChemoSen↑, 17,   ChemoSen∅, 1,   CompStab↑, 1,   Dose↑, 1,   Dose↝, 13,   eff?, 1,   eff↑, 9,   eff↝, 2,   Half-Life↓, 2,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 2,   RadioS↑, 4,   selectivity↑, 7,   Synergy↑, 18,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   ALP↓, 1,   AST↓, 2,   BRCA1↑, 1,   BUN↓, 3,   CEA↓, 1,   creat↓, 4,   E6↓, 1,   E7↓, 1,   EGFR↓, 3,   EGFR↑, 1,   EZH2↓, 1,   HER2/EBBR2↓, 2,   hTERT/TERT↓, 2,   IL6↓, 5,   LDH↓, 2,   LDH↑, 1,   Maspin↑, 1,   PC↑, 1,   PD-L1↓, 3,   PSA↓, 1,   RBC↑, 1,   Urea↓, 1,   WBC↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 1,   AntiCan↑, 7,   AntiTum↑, 6,   cardioP↑, 4,   CardioT↓, 1,   chemoP↑, 16,   chemoPv↑, 3,   GFR↑, 1,   hepatoP↑, 9,   hepatoP∅, 1,   Mucositis↓, 2,   neuroP↑, 7,   NP/CIPN↓, 1,   NP/CIPN↑, 1,   Pain↓, 1,   PFS↑, 1,   QoL↑, 3,   radioP↑, 3,   RenoP↓, 1,   RenoP↑, 33,   RenoP∅, 1,   Risk↓, 1,   toxicity↓, 3,   toxicity↝, 2,   TumVol?, 1,   TumVol↓, 1,   TumW↓, 1,   Weight?, 1,  

Infection & Microbiome(tgid=24) ⓘ

Sepsis↓, 1,  
Total Targets: 380

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 50,   ARE↑, 1,   Bil↓, 1,   Bil↑, 1,   Catalase↑, 30,   Copper↓, 1,   Fenton↓, 3,   GCLC↑, 1,   GCLM↑, 1,   GPx↓, 1,   GPx↑, 16,   GPx4↑, 3,   GSH↑, 39,   GSR↓, 1,   GSR↑, 5,   GSTs↓, 1,   GSTs↑, 8,   H2O2↓, 2,   HDL↑, 3,   HO-1↓, 1,   HO-1↑, 27,   HO-1⇅, 1,   Iron↓, 2,   Iron∅, 1,   Keap1↓, 3,   Keap1↑, 1,   lipid-P↓, 28,   MDA↓, 35,   MPO↓, 5,   NADH↓, 1,   NOX4↓, 2,   NQO1↑, 4,   NQO1↝, 1,   NRF2↓, 2,   NRF2↑, 37,   Prx↑, 1,   RNS↓, 1,   ROS↓, 80,   ROS⇅, 1,   ROS∅, 1,   SOD?, 1,   SOD↑, 39,   SOD1↑, 1,   SOD2↑, 1,   TAC↑, 6,   TBARS↓, 1,   Trx1↑, 1,   UCPs↑, 1,   uricA↓, 5,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 4,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compII↑, 1,   compIII↑, 1,   DRP1/DNM1L↓, 1,   MFN2↑, 2,   mtDam↓, 2,   PGC-1α↑, 1,   PINK1↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   15-LOX/ALOX15↓, 1,   ALAT↓, 19,   ALAT∅, 1,   AMPK↑, 4,   p‑AMPK↑, 1,   ATP↑, 5,   Buty↑, 1,   cAMP↑, 1,   CRM↑, 1,   glucose↓, 1,   glucose↝, 1,   GlucoseCon↑, 1,   GSK‐3β↓, 2,   GSK‐3β↑, 2,   p‑GSK‐3β↑, 1,   HMG-CoA↓, 1,   KeyT↝, 1,   LDL↓, 6,   lipidLev↓, 2,   NADPH↓, 4,   PLA2↓, 1,   SCFAs↑, 1,   SIRT1↓, 1,   SIRT1↑, 7,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 16,   ASC↓, 2,   BAX↓, 8,   Bax:Bcl2↓, 1,   Bcl-2↑, 7,   Casp1↓, 2,   Casp12↓, 3,   Casp3?, 1,   Casp3↓, 15,   Casp3∅, 1,   cl‑Casp3↓, 1,   cl‑Casp8↑, 1,   Casp9↓, 5,   Casp9∅, 1,   Cyt‑c↓, 3,   Cyt‑c∅, 1,   Fas↓, 2,   Ferroptosis↓, 7,   GranB/GZMB↓, 1,   iNOS↓, 13,   iNOS↑, 2,   p38↓, 4,   Pyro↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 3,   Akt↑, 5,   p‑Akt↑, 2,   ERK↓, 4,   ERK↑, 1,   p‑ERK↑, 1,   HGF/c-Met↑, 1,   IKKα↑, 1,   JAK2↓, 1,   JNK↓, 4,   JNK↑, 1,   p‑JNK↓, 1,   MAPK↓, 8,   MAPK↑, 1,   p‑MAPK↓, 1,   mTOR↓, 3,   mTOR↑, 1,   PI3K↓, 4,   PI3K↑, 4,   PKCδ?, 1,   STAT3↓, 2,   STAT5↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   ATF2↑, 1,   ATF4↓, 1,   cMyc↓, 1,   DNMT1↓, 2,   DNMTs↓, 1,   FOXO3↑, 1,   KLF4↑, 1,   other↓, 1,   other↑, 4,   other↝, 2,   other∅, 1,   Prot↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 3,   CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   ER Stress↓, 4,   GRP78/BiP↓, 3,   GRP78/BiP↑, 1,   GRP94↑, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   MitoP↓, 1,   p62↓, 1,   PARK2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 5,   DNArepair↑, 1,   p16↓, 1,   P53↓, 2,   PARP∅, 1,   PARP1↓, 1,   PCNA↓, 1,   SIRT6↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

HH↓, 1,   IGF-1↑, 1,   IGFBP1↑, 1,   neuroG↑, 1,   TumCP↓, 1,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 4,   AP-1↓, 2,   mt-ATPase↑, 1,   BACH1↓, 1,   Ca+2↓, 1,   Ca+2↝, 2,   Cartilage↑, 2,   COL1↓, 1,   Fibrosis↓, 1,   LRP1↑, 1,   MMP13↓, 2,   MMP9↓, 1,   MUC1↑, 1,   PAI-1/SERPINE1↓, 1,   p‑Rac1↓, 1,   TGF-β↓, 2,   TGF-β↑, 1,   TGF-β1↓, 1,   TumCI↓, 1,   TXNIP↓, 1,   α-SMA↓, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

eNOS↑, 1,   Hif1a↓, 1,   NO↓, 9,   VCAM-1↓, 4,   VEGF↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 5,   BBB↝, 1,   GastroP↑, 4,   GLUT2↑, 1,   GLUT4↑, 1,   H+/K+-ATPase↓, 1,   IBI↑, 4,   MMP↑, 6,   NHE3↑, 1,   TJ↑, 1,   TRPV1↑, 2,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 2,   CD8+↑, 1,   COX1↓, 2,   COX2/PTGS2↓, 21,   HMGB1↓, 1,   ICAM-1↓, 3,   IFN-γ↓, 3,   IL1↓, 2,   IL10↓, 6,   IL10↑, 3,   IL12↓, 1,   IL17↓, 1,   IL18↓, 2,   IL1β↓, 23,   IL2↓, 2,   IL4↓, 3,   IL5↓, 1,   IL6↓, 26,   IL6↑, 2,   IL8↓, 6,   Imm↑, 5,   Inflam↓, 56,   Inflam↑, 1,   IRF3↓, 2,   LPS↓, 1,   MCP1/CCL2↓, 2,   MCT1↓, 1,   MyD88↓, 4,   NeuroI↓, 1,   NF-kB↓, 27,   NLRP3↓, 7,   PGE2↓, 5,   RAGE↓, 2,   RANTES↓, 1,   TLR2↓, 3,   TLR4↓, 9,   TNF-α↓, 38,   TRIF↓, 2,   VitD↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 7,   BChE↓, 3,   BDNF↑, 3,   ChAT↑, 1,   GABA↑, 1,   NGF↑, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 2,   APP↓, 1,   Aβ↓, 10,   BACE/β-secretase↓, 4,   p‑tau↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 2,   ACE2↓, 1,   GLP-1R↑, 1,   NR1H4↑, 1,   PPARα↑, 1,   PPARγ↓, 1,   PPARγ↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 16,   BioAv↑, 18,   BioAv↝, 5,   ChemoSen↑, 2,   Dose↝, 14,   eff↓, 1,   eff↑, 11,   GSTA1↑, 1,   Half-Life↓, 3,   Half-Life↑, 2,   Half-Life↝, 5,   MRP↓, 1,   P-gp/ABCB1↓, 2,   selectivity↑, 1,   Synergy↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 19,   ALAT∅, 1,   ALB↑, 1,   ALB↝, 1,   ALP↓, 5,   AST↓, 19,   AST∅, 1,   BG↓, 2,   Bil↓, 1,   Bil↑, 1,   BloodF↑, 2,   BMD↑, 2,   BP↓, 4,   BUN?, 1,   BUN↓, 10,   CCr / CrCl↓, 1,   CCr / CrCl∅, 1,   creat↓, 20,   CRP↓, 1,   IL6↓, 26,   IL6↑, 2,   IRes↝, 1,   KeyT↝, 1,   LDH↓, 4,   NOS2↓, 1,   RAGE↓, 2,   Urea↓, 5,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   AntiAge↑, 2,   antiAll↑, 2,   AntiArt↑, 3,   AntiCan↑, 8,   antiD↓, 1,   AntiDiabetic↑, 11,   antiM↑, 1,   antiPs↑, 2,   antiPy↑, 1,   AntiTum↑, 3,   cardioP?, 2,   cardioP↑, 30,   cardioP⇅, 1,   chemoP↑, 11,   chemoPv↑, 1,   cognitive↑, 9,   diuretic↑, 3,   GFR↓, 1,   GFR↑, 1,   GFR∅, 1,   hepatoP↑, 48,   memory?, 1,   memory↑, 7,   motorD↑, 1,   Mucositis↓, 1,   neuroP?, 1,   neuroP↑, 33,   Obesity↓, 8,   OS↑, 2,   Pain↓, 2,   QoL↑, 2,   radioP↑, 5,   RenoP↓, 2,   RenoP↑, 96,   RenoP↝, 2,   Strength↑, 1,   Stress↓, 1,   Stroke↓, 6,   toxicity↓, 14,   toxicity↝, 2,   toxicity∅, 2,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 4,   AntiFungal↑, 4,   AntiP↑, 1,   AntiViral↑, 4,   Bacteria↓, 11,   GutMicro↑, 7,   Sepsis↓, 5,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 2,  
Total Targets: 361

Scientific Paper Hit Count for: RenoP, K,Renoprotection/Nephroprotective
14 Thymoquinone
12 Cisplatin
5 Baicalein
5 Hydrogen Gas
5 Lycopene
4 Berberine
4 Chrysin
3 Silver-NanoParticles
3 Ashwagandha(Withaferin A)
3 Melatonin
3 Boron
3 Capsaicin
3 Licochalcone A
3 Morin
3 Selenium NanoParticles
3 Shikonin
2 Allicin (mainly Garlic)
2 Alpha-Lipoic-Acid
2 Curcumin
2 EGCG (Epigallocatechin Gallate)
2 Betulinic acid
2 Carvacrol
2 Chlorogenic acid
2 Dandelion Root
2 Ferulic acid
2 Fisetin
2 Grapeseed extract
2 Hibiscus sabdariffa
2 Hyperoside
2 Isoliquiritigenin
2 Isovitexin
2 Linalool
2 Luteolin
2 Chemotherapy
2 Moringa oleifera
2 5-fluorouracil
2 Marjoram (Origanum majorana)
2 Resveratrol
2 Rutin
2 Silymarin (Milk Thistle) silibinin
1 Annona atemoya Seed Extract
1 Astragalus
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Apigenin (mainly Parsley)
1 doxorubicin
1 Ascorbyl Palmitate
1 Huperzine A/Huperzia serrata
1 α-Bisabolol / Chamomile oil
1 Black Seed Oil/Nigella sativa
1 Lecithin
1 Coenzyme Q10
1 Selenium
1 Crocetin
1 Cucurbitacin
1 D-limonene
1 Echinacea
1 Emodin
1 Fucoidan
1 Ginkgo biloba
1 Germanium inorganic
1 Honokiol
1 phytic acid, Inositol hexakisphosphate
1 isoorientin
1 Kaempferol
1 Licorice
1 Lactoferrin/Talactoferrin
1 Lemongrass Extract/Citral
1 Magnesium
1 Bicarbonate(Sodium)
1 Propolis -bee glue
1 Quercetin
1 Rosmarinic acid
1 buckwheat sprouts
1 Gold NanoParticles
1 Date Fruit Extract
1 Sulforaphane (mainly Broccoli)
1 Selenite (Sodium)
1 Matrine
1 Radiotherapy/Radiation
1 methotrexate
1 Thymol-Thymus vulgaris
1 Urolithin
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1175  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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