creat Cancer Research Results

creat, creatinine: Click to Expand ⟱
Source:
Type:
Creatinine is fundamentally a metabolic waste product derived from creatine phosphate in muscle. Its blood levels are routinely used as a clinical biomarker to assess kidney function rather than a direct regulator of oncogenic processes.
Creatinine is a primary marker used to estimate the glomerular filtration rate (GFR).

-Elevated creatinine can be a sign of compromised kidney vascular function.
Scientific Papers found: Click to Expand⟱
2660- AL,    Allicin: A review of its important pharmacological activities
- Review, AD, NA - Review, Var, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2↓, p‑FAK↓,
3456- ALA,    Renal-Protective Roles of Lipoic Acid in Kidney Disease
- Review, NA, NA
*RenoP↑, *ROS↓, *antiOx↑, *Inflam↓, *Sepsis↓, *IronCh↑, *BUN↓, *creat↓, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *chemoP↑, *eff↑, *NF-kB↓,
3170- Ash,    Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms
- in-vitro, Nor, NRK52E - in-vivo, NA, NA
*RenoP↑, *hepatoP↑, *creat↓, *BUN↓, *uricA↓, *Apoptosis↓, *α-SMA↓,
3505- Bor,    Mineral requirements for mitochondrial function: A connection to redox balance and cellular differentiation
- Review, NA, NA
*glucose↓, *creat↓, *SOD↑, *MMP↑, *ROS↓,
6542- BSB,    Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol
- Review, Var, NA - Review, Park, NA - Review, AD, NA
AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL6↑, *MMP13↓,
5898- CAR,    Carvacrol-induced apoptosis via tumor suppressor gene activation and oxidative stress modulation in a rat model of breast cancer
- in-vivo, BC, NA
*lipid-P↓, *MDA↓, *antiOx↑, *Inflam↑, RenoP↑, hepatoP↑, *ALAT↓, AST↓, creat↓, chemoPv↑, Cyt‑c↑, FADD↑, P53↑,
6282- DL,    Limonene Exerts Anti-Inflammatory Effect on LPS-Induced Jejunal Injury in Mice by Inhibiting NF-κB/AP-1 Pathway
- in-vivo, IBD, NA
*RenoP↑, *creat↓, *Inflam↓, *TNF-α↓, *IL1β↓, *COX2↓, *ROS↓, *NRF2↑, *GastroP↑, *TLR4↓, *NF-kB↓, *AP-1↓, *Sepsis↓,
6347- DRE,    Protective Effects of Taraxacum officinale L. (Dandelion) Root Extract in Experimental Acute on Chronic Liver Failure
*hepatoP↑, *AST↓, *ALAT↓, *ALP↓, *Bil↓, *creat↓, *TOS↑,
6353- DRE,  Cisplatin,    Insights Into Protective Mechanisms of Dandelion Leaf Extract Against Cisplatin-Induced Nephrotoxicity in Rats: Role of Inhibitory Effect on Inflammatory and Apoptotic Pathways
- in-vivo, Nor, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Cyt‑c↓, *DNAdam↓, *GSH↑, *SOD↑, *Albumin↝, *creat↓, *BUN↓, *RenoP↑, *lipid-P↓, *TNF-α↓, *Casp3↓, *Casp9↓, *chemoP↑,
4022- FulvicA,  Chemo,    Shilajit potentiates the effect of chemotherapeutic drugs and mitigates metastasis induced liver and kidney damages in osteosarcoma rats
- in-vivo, OS, NA
AST↓, ALAT↓, ALP↓, Bil↝, creat↓, uricA↓, ChemoSen↑, chemoP↑,
3264- Lyco,    Pharmacological potentials of lycopene against aging and aging‐related disorders: A review
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *GSTs↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *iNOS↓, *NO↓, *TAC↑, *NOX4↓, *Inflam↓, *IL1↓, *IL6↓, *IL8↓, *IL1β↓, *TNF-α↓, *TLR2↓, *TLR4↓, *VCAM-1↓, *ICAM-1↓, *STAT3↓, *NF-kB↓, *ERK↓, *BP↓, ROS↓, PGE2↓, cardioP↑, *neuroP↑, *creat↓, *RenoP↑, *CRM↑,
3842- Moringa,    Bioactive Components in Moringa Oleifera Leaves Protect against Chronic Disease
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *hepatoP↑, *lipid-P↓, *ALAT↓, *AST↓, *ALP↓, *creat↓, *RenoP↑, NF-kB↓, ChemoSen↑, *memory?,
2933- NAD,    Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns
- Review, Nor, NA - NA, AD, NA - NA, Diabetic, NA - NA, Stroke, NA - NA, LiverDam, NA - NA, Park, NA
*mtDam↓, *BioAv↝, *BioAv↑, *OS↑, *eff↑, *eff↑, *cognitive↑, *DNAdam↓, *SIRT1↑, *cardioP↑, *ROS↓, *Dose↝, *BioAv↑, *hepatoP↑, *eff↑, *BG↓, *creat↓,
3014- RosA,    Rosmarinic Acid Supplementation Acts as an Effective Antioxidant for Restoring the Antioxidation/Oxidation Balance in Wistar Rats with Cadmium-Induced Toxicity
- in-vivo, Nor, NA
*antiOx↑, *Thiols↑, *GSH↑, *TAC↑, *SOD↑, *GPx↑, *Catalase↑, *ALP↓, *ALAT↓, *AST↓, *creat↓, *BUN↓, *H2O2↓, *MDA↓, *ROS↓, cardioP↑, hepatoP↑, neuroP↑,
4755- Se,  Chemo,    Selenium Prevention of Alopecia, Bladder and Kidney Toxicity Induced by Chemotherapeutic Agents
- in-vitro, Var, NA
chemoP↑, creat↓, BUN↓,
4453- SeNPs,    Selenium Nanoparticles: Green Synthesis and Biomedical Application
- Review, NA, NA
*toxicity↓, *Bacteria↓, ROS↑, MMP↓, ER Stress↑, P53↑, Apoptosis↑, Casp9↑, DNAdam↑, TumCCA↑, eff↑, Catalase↓, SOD↓, GSH↓, selectivity↓, selectivity↑, PCNA↓, eff↑, *ALAT↓, *AST↓, *ALP↓, *creat↓, *Inflam↓, *toxicity↓, selectivity↑,
3313- SIL,    Silymarin attenuates post-weaning bisphenol A-induced renal injury by suppressing ferroptosis and amyloidosis through Kim-1/Nrf2/HO-1 signaling modulation in male Wistar rats
- in-vivo, NA, NA
*NRF2↑, *HO-1↑, *creat↓, *BUN↓, *RenoP↑, *MDA↓, *TNF-α↓, *IL1β↓, *Cyt‑c↓, *Casp3↓, *GSTs↓, *GSH↑, *GPx4↑, *SOD↑, *GSR↓, *Ferroptosis↓,
4126- Silicon,  H2,    Oral Administration of Si-Based Agent Attenuates Oxidative Stress and Ischemia-Reperfusion Injury in a Rat Model: A Novel Hydrogen Administration Method
- in-vivo, NA, NA
*creat↓, *ROS↓, *other↑, *MDA↓, *other↑, *Inflam↓,
2113- TQ,    Potential role of Nigella sativa (NS) in abating oxidative stress-induced toxicity in rats: a possible protection mechanism
- in-vivo, Nor, NA
*antiOx↑, *RenoP↑, *hepatoP↑, *SOD↑, *GSH↑, *ROS↓, *lipid-P↓, ALAT↓, creat↓,
2133- TQ,  CUR,  Cisplatin,    Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NFκB, KIM-1 and ameliorating Nrf2/HO-1 signalling
- in-vitro, Nor, HEK293 - in-vivo, NA, NA
*creat↓, *TNF-α↓, *IL6↓, *MRP↓, *GFR↑, *mt-ATPase↑, *p‑Akt↑, *NRF2↑, *HO-1↑, *Casp3↓, *NF-kB↓, *RenoP↑,

Showing Research Papers: 1 to 20 of 20

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 20

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Bil↝, 1,   Catalase↓, 1,   GSH↓, 2,   ROS↓, 1,   ROS↑, 2,   SOD↓, 1,   uricA↓, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 2,   BUN↓, 1,  

Cell Death ⓘ

Akt↓, 1,   Apoptosis↑, 2,   Bak↓, 1,   BAX↑, 1,   Bcl-2↓, 2,   BID↑, 1,   Casp12↑, 1,   Casp3↑, 2,   Casp8↑, 2,   Casp9↑, 3,   Cyt‑c↑, 3,   FADD↑, 1,   Fas↑, 2,   p38↑, 1,  

Kinase & Signal Transduction ⓘ

HER2/EBBR2↓, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↑, 1,  

DNA Damage & Repair ⓘ

CHK1↓, 1,   DNAdam↑, 1,   P53↑, 4,   PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence ⓘ

CycB/CCNB1↓, 1,   P21↑, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State ⓘ

FGF↓, 1,   STAT3↓, 1,  

Migration ⓘ

CEA↓, 1,   p‑FAK↓, 1,   TIMP2↑, 1,   TumCMig↓, 1,  

Angiogenesis & Vasculature ⓘ

EGFR↑, 1,   Hif1a↓, 1,   VEGF↓, 1,   VEGFR2↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   IL8↓, 1,   NF-kB↓, 1,   NF-kB↑, 1,   PGE2↓, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 2,   eff↑, 2,   RadioS↑, 1,   selectivity↓, 1,   selectivity↑, 2,  

Clinical Biomarkers ⓘ

ALAT↓, 2,   ALP↓, 1,   AST↓, 2,   Bil↝, 1,   CEA↓, 1,   creat↓, 4,   EGFR↑, 1,   HER2/EBBR2↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 2,   cardioP↑, 2,   chemoP↑, 3,   chemoPv↑, 1,   hepatoP↑, 2,   neuroP↑, 1,   RenoP↑, 1,  
Total Targets: 70

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

AntiBio↑, 2,  

Redox & Oxidative Stress ⓘ

antiOx↑, 10,   Bil↓, 1,   Catalase↑, 4,   Ferroptosis↓, 1,   GPx↑, 1,   GPx4↑, 1,   GSH↑, 8,   GSR↓, 1,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 1,   HO-1↑, 4,   Keap1↓, 1,   Keap1↑, 1,   lipid-P↓, 7,   MDA↓, 8,   MPO↓, 1,   NOX4↓, 1,   NQO1↑, 1,   NRF2↑, 6,   ROS↓, 12,   SOD↑, 9,   TAC↑, 2,   TBARS↓, 2,   Thiols↑, 1,   TOS↑, 1,   uricA↓, 2,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↑, 1,   MMP↑, 2,   mtDam↓, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 6,   BUN↓, 5,   CRM↑, 1,   glucose↓, 1,   H2S↑, 1,   LDH↓, 2,   SIRT1↑, 1,  

Cell Death ⓘ

Akt↓, 1,   p‑Akt↑, 1,   Apoptosis↓, 3,   BAX↓, 1,   Bcl-2↑, 1,   Casp3↓, 4,   Casp9↓, 1,   Cyt‑c↓, 3,   Ferroptosis↓, 1,   iNOS↓, 4,  

Transcription & Epigenetics ⓘ

other↑, 3,  

DNA Damage & Repair ⓘ

DNAdam↓, 2,  

Proliferation, Differentiation & Cell State ⓘ

ERK↓, 1,   PI3K↓, 1,   STAT3↓, 1,  

Migration ⓘ

AP-1↓, 1,   mt-ATPase↑, 1,   MMP13↓, 1,   VCAM-1↓, 1,   α-SMA↓, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 2,  

Barriers & Transport ⓘ

BBB↑, 2,   GastroP↑, 2,   MRP↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD4+↑, 1,   COX2↓, 4,   ICAM-1↓, 1,   IL1↓, 1,   IL1β↓, 5,   IL6↓, 5,   IL6↑, 1,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 8,   Inflam↑, 1,   NF-kB↓, 6,   PGE2↓, 1,   TLR2↓, 1,   TLR4↓, 2,   TNF-α↓, 9,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,   BChE↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,   BACE↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 4,   BioAv↝, 1,   Dose↝, 1,   eff↑, 6,   Half-Life↝, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 6,   Albumin↝, 1,   ALP↓, 4,   AST↓, 5,   BG↓, 1,   Bil↓, 1,   BP↓, 2,   creat↓, 16,   GutMicro↑, 1,   IL6↓, 5,   IL6↑, 1,   LDH↓, 2,  

Functional Outcomes ⓘ

cardioP↑, 4,   chemoP↑, 2,   cognitive↑, 2,   GFR↑, 1,   hepatoP↑, 6,   memory?, 1,   memory↑, 1,   motorD↑, 1,   neuroP↑, 4,   OS↑, 1,   Pain↓, 1,   RenoP↑, 10,   toxicity↓, 3,  

Infection & Microbiome ⓘ

AntiFungal↑, 1,   Bacteria↓, 1,   CD8+↑, 1,   Sepsis↓, 2,  
Total Targets: 117

Scientific Paper Hit Count for: creat, creatinine
2 Dandelion Root
2 Cisplatin
2 Chemotherapy
2 Thymoquinone
1 Allicin (mainly Garlic)
1 Alpha-Lipoic-Acid
1 Ashwagandha(Withaferin A)
1 Boron
1 α-Bisabolol / Chamomile oil
1 Carvacrol
1 D-limonene
1 Shilajit/Fulvic Acid
1 Lycopene
1 Moringa oleifera
1 nicotinamide adenine dinucleotide
1 Rosmarinic acid
1 Selenium
1 Selenium NanoParticles
1 Silymarin (Milk Thistle) silibinin
1 Silicic Acid
1 Hydrogen Gas
1 Curcumin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1251  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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