AntiFungal Cancer Research Results

AntiFungal, AntiFungal: Click to Expand ⟱
Source:
Type:
AntiFungal
Scientific Papers found: Click to Expand⟱
6461- 1,8-Cin,    1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases
- Review, AD, NA - Review, Var, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *Half-Life↝, *toxicity↓, *PGE2↓, *TNF-α↓, *IL1β↓, *NO↓, *NF-kB↓, *PPARγ↓, COX2/PTGS2↓, *ROS↓, *SOD↑, *Catalase↑, *TAC↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *NADPH↑, *GPx↑, *AntiBio↑, *Synergy↑, *AntiFungal↑, *AntiViral↑, *TRPA1↑, Synergy↑, TumCCA↑, ROS↑, MAPK↝, mTOR↝, Apoptosis↑, survivin↓, Akt↓, p38↑, cl‑PARP↑, cl‑Casp3⇅, P53↑, BAX↑, Cyt‑c↑, Casp9↑, Dose↝, *Aβ↓, *tau↓, *GSK‐3β↓, *BACE/β-secretase↓, *cardioP↑, MFN2↑, *antiAll↑,
6462- 1,8-Cin,    Modes of Action of 1,8-Cineol in Infections and Inflammation
- Review, Var, NA - Review, AD, NA
*BioAv↑, *BBB↑, *AntiViral↑, *Bacteria↓, *AntiFungal↑, *Inflam↓, *BioAv↑, *MUC2↓, *MUC19↓, *NF-kB↓, *ICAM-1↓, *VCAM-1↓, DNAdam↑, *lipid-P↓, *PGE2↓, *IL4↓, *IL6↓, *IL1β↓, *IL6↓, Synergy↑, TGF-β↓, fascin↓, VEGF↓, MMP9↓, *MAPK↓, *ERK↓, JNK↓, Wnt↓, β-catenin/ZEB1↓, GSK‐3β↑, *neuroP↑, *GSK‐3β↓, *AGEs↓, *BBB↑, *NLRP3↓,
4549- AgNPs,    Silver nanoparticles: Synthesis, medical applications and biosafety
- Review, Var, NA - Review, Diabetic, NA
ROS↑, eff↑, other↝, DNAdam↑, EPR↑, eff↑, eff↑, TumMeta↓, angioG↓, *Bacteria↓, *eff↑, *AntiViral↑, *AntiFungal↑, eff↑, eff↑, TumCP↓, tumCV↓, P53↝, HIF-1↓, TumCCA↑, lipid-P↑, ATP↓, Cyt‑c↑, MMPs↓, PI3K↓, Akt↓, *Wound Healing↑, *Inflam↓, *Bone Healing↑, *glucose↓, *AntiDiabetic↑, *BBB↑,
6763- AL,    Revealing the Therapeutic Uses of Garlic (Allium sativum) and Its Potential for Drug Discovery
- Review, Nor, NA
*Inflam↓, *AntiBio↑, *AntiDiabetic↑, *hepatoP↑, *antiOx↑, *AntiFungal↑, *Wound Healing↑, *other↑, *BP↓, *LDL↓, *AntiAg↑, *cognitive↑, *memory↑, Risk↑, *COX1↓, *TXA2↓, *antiAll↑,
7403- Amla,    Aqueous Extract of Emblica officinalis Linn (Indian gooseberry) in Combination with Iodine is More Efficacious than Iodine Alone in Mitigating Mucositis in Head and Neck Cancer Patients Undergoing Curative Radiotherapy: Retrospective Observations
- Trial, HNSCC, NA
Mucositis↓, Dose↝, Dose↝, *Bacteria↓, *AntiFungal↑, *AntiViral↑, *hepatoP↑, *RenoP↑, *neuroP↑, Dose↝,
6600- Anamu,  AgNPs,    Characterization, antimicrobial, antioxidant, and anticoagulant activities of silver nanoparticles synthesized from Petiveria alliacea L. leaf extract
- in-vitro, Nor, NA
*Bacteria↓, *AntiFungal↑, *AntiAg↑,
6542- BSB,    Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol
- Review, Var, NA - Review, Park, NA - Review, AD, NA
AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2/PTGS2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE/β-secretase↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2/PTGS2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL6↑, *MMP13↓,
6648- Cen,    Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential
- Review, AD, NA
*neuroP↑, *Aβ↓, *ROS↓, *Wound Healing↑, *memory↑, *Inflam↓, *hepatoP↑, *Imm↑, *cardioP↑, *AntiDiabetic↑, *AntiFungal↑, *antiOx↑, *Dose↝, *AChE↓, *BChE↓, *Tyro3↓, *lipid-P↓,
6773- Cin,    Cinnamaldehyde in Focus: Antimicrobial Properties, Biosynthetic Pathway, and Industrial Applications
- Review, Nor, NA
*AntiBio↑, *AntiFungal↓, *AntiDiabetic↑, *Inflam↓, *ROS↑, ROS↑, TumCCA↑,
6520- CRV,    Health Benefits and Pharmacological Properties of Carvone
- Review, Nor, NA
*Bacteria↓, *AntiFungal↑, *antiOx↑, *Inflam↓, AntiCan↑, *AntiDiabetic↑, *Obesity↓, TumCCA↑, *AntiArt↑, Imm↑, *P450↓, *GSR↑, GSTs↑, GSH↑, BAX↑, Casp3↑, TumCP↓, TumCMig↓, Apoptosis↑,
8844- DIM,  I3C,    Unveiling the Multifaceted Pharmacological Actions of Indole-3-Carbinol and Diindolylmethane: A Comprehensive Review
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *Imm↝, *BioAv↝, *Half-Life↝, *PKCδ↓, *TGF-β1↓, *PPARγ↓, *CEBPA↓, *FABP4↓, *AMPKα↑, *MCP1/CCL2↓, *IL6↓, *TNF-α↓, *Akt↑, *Inflam↓, *TMAO↓, *SREBF2⇅, *memfluid↑, *GutMicro↑, *Obesity↓, *hepatoP↑, *neuroP↑, *AntiAg↓, *Stroke↓, *AntiAg↓, *HDAC↑, *IL1β↓, *IL6↓, *iNOS↓, *IL4↑, *IL10↑, *Synergy↑, *compI↑, *ROS↓, *AChE↓, *BChE↓, *MAOA↓, *MAOB↓, *cognitive↑, *Analgesic↑, *Pain↓, *BDNF↑, *TrkB↑, *Akt↑, *antiOx↑, *Apoptosis↓, *cardioP↑, *chemoP↑, *AntiThr↑, *uPA↑, *NRF2↑, *ARE↑, *HO-1↑, *Bacteria↓, *TOP1↓, *AntiFungal↑, *AntiViral↑, *radioP↑, *Synergy↑, *hepatoP↑, *Diar↓, *ChemoSen↑, *Telomerase↓, *BioAv↓,
6772- Eug,    Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiBio↑, *Bacteria↓, *AntiFungal↑,
6925- Flav,    Important Flavonoids and Their Role as a Therapeutic Agent
- Review, Nor, NA
AntiCan↑, *antiOx↑, *Inflam↓, *AntiViral↑, *neuroP↑, *cardioP↑, *AChE↓, *cognitive↑, Risk↓, *Stroke↓, *AntiDiabetic↑, *AntiFungal↑,
6924- Flav,    Plant Flavonoids: Chemical Characteristics and Biological Activity
- Review, Nor, NA
*ROS↓, *antiOx↑, *Inflam↓, *Bacteria↓, *cardioP↑, AntiCan↑, *AntiAge↑, *AntiDiabetic↑, AntiViral↑, *BioAv↓, *AntiFungal↑,
7124- Ge-132,    Physiological Activity of Trace Element Germanium including Anticancer Properties
- Review, Var, NA
*toxicity↓, Risk↓, Dose↝, AntiCan↑, AntiTum↑, Inflam↓, OXPHOS↝, *toxicity↓, *toxicity↓, other↑, Synergy↑, *Bacteria↓, *AntiFungal↑, eff↑, Synergy↑, ROS↑, Synergy↑, toxicity↝, *H2O2↓, *ROS↓, Warburg↓,
7260- Gink,    Ginkgetin: A natural biflavone with versatile pharmacological activities
- Review, Var, NA - Review, Stroke, NA - Review, AD, NA
*AntiCan↑, *Inflam↓, *AntiBio↑, *neuroP↑, *TumCCA↑, Apoptosis↑, TumAuto↑, iNOS↓, COX2/PTGS2↓, PGE2↓, NF-kB↓, PLA2↓, *neuroP↑, *Stroke↓, *AntiFungal↓, *Bacteria↓, Bcl-xL↓, Bcl-2↓, Casp9↑, Casp3↑, cl‑PARP↑, IL6↓, STAT3↓, JAK1↓, survivin↓, COX2/PTGS2↓, IAP1↓, MMP2↓, MMP9↓, PTEN↑, SHP1↑, Synergy↑, TumVol↓, TumW↓, *toxicity↓, *ROS↓,
7565- HYP,    Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review
- Review, AD, NA
*Inflam↓, *antiOx↑, *neuroP↑, *lipid-P↓, *ROS↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *MDA↓, *BAX↓, *Casp3↓, *Catalase↑, *SOD↑, *GSH↑, *BDNF↑, *TrkB↑, *NGF↑, *BDNF↑, *NF-kB↓, *AChE↓, *H2S↑, Casp3↑, Apoptosis↑, NF-kB↓, AMPK↑, HO-1↑, MAPK↑, cl‑Casp3↑, cl‑Casp9↑, BAX↑, SOD?, Catalase↓, NRF2↓, NQO1↓, HO-1↓, Bcl-2↓, TumCCA↑, FOXO1↑, TumAuto↑, Akt↓, mTOR↓, P70S6K↓, BMP7/OP1↓, *cardioP↑, *hepatoP↑, *antiCG↑, *AntiThr↑, *Diar↓, *AntiFungal↑, *CYP2D6↓, *PDGFR-BB↓, *PDGFRB↓, *toxicity↓, *Half-Life↑,
7769- IBC,    Potential Determinants for Metabolic Fates and Inhibitory Effects of Isobavachalcone Involving in Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Efflux Transporters
- in-vivo, Var, NA
*AntiCan↑, *AntiAg↑, *AntiFungal↑, CYP2C9↓, UGT1A↓, CYP2D6↓, CYP2E1↓,
7995- itraC,    Repurposing itraconazole in clinical dermato-oncology beyond conventional antifungal use: a review
- Review, Var, NA
*AntiFungal↑, Shh↓, Smo↓,
8001- itraC,    Repurposing itraconazole as an anticancer agent
- Review, Var, NA
*AntiFungal↑, AntiCan↑, P-gp/ABCB1↓, HH↓, mTOR↓, Wnt↓, β-catenin/ZEB1↓, angioG↓, LymphAG↓, ChemoSen↑, OS↑, Gli1↓, Ki-67↓, CSCs↓,
8013- itraC,    High-dose itraconazole as a non-castrating therapy for a patient with biochemically-recurrent prostate cancer
- Case Report, Pca, NA
*AntiFungal↑, antiNeop↑, HH↓, Dose↝, OS↑, testos∅, Dose↝, PSA↓, other↝, other↝, HH↓,
8019- itraC,    Itraconazole Inhibits AKT/mTOR Signaling and Proliferation in Endometrial Cancer Cells
- in-vitro, Endo, AN3CA - in-vitro, Endo, HEC-1A - in-vitro, Endo, HEC-50B - in-vitro, Endo, SNG-II
*AntiFungal↑, TumCP↓, mTOR↓, LC3II↑, TumAuto↑, Akt↓,
5113- JG,    Juglone in Oxidative Stress and Cell Signaling
- Review, Var, NA - Review, AD, NA
ROS↑, Pin1↓, antiOx⇅, *ROS↓, SMAD2↓, GSH↓, lipid-P↑, TumCCA↓, BAX↑, Bcl-2↓, Casp3↑, Casp9↑, Ca+2↑, Cyt‑c↑, AntiFungal↑, Bacteria↓, Akt↓,
8088- KAE,    Kaempferol: Antimicrobial Properties, Sources, Clinical, and Traditional Applications
- Review, Nor, NA
*AntiCan↓, *Inflam↓, *Bacteria↓, *AntiFungal↑, *BioAv↝,
8229- LCA,    Licochalcone A: a review of its pharmacology activities and molecular mechanisms
- Review, Nor, NA
*Inflam↓, *NO↓, *NF-kB↓, *TAC↑, Apoptosis?, TumCCA↑, TumCI↓, TumMeta↓, TumCP↓, MAPK↓, Akt↓, IL6↓, IL8↓, VEGFR2/KDR/Flk1↓, LC3II↑, PI3K↓, mTOR↓, mtDam↑, MMP↓, *NRF2↑, *PGE2↓, *Obesity↓, *SIRT1↑, *AMPK↑, *AntiFungal↑, *AntiP↑, *BMD↑, *GastroP↑,
8129- LF,    Study on the Therapeutic Benefit on Lactoferrin in Patients with Colorectal Cancer Receiving Chemotherapy
- Trial, CRC, NA
Dose↝, toxicity↓, INF-γ↝, other↑, *ROS↓, Imm↑, WBC↑, Neut↑, T-Cell↑, *antiOx↑, *GSH↑, *chemoP↑, *RenoP↑, *hepatoP↑, BUN↓, creat↓, ALAT↓, AST↓, RBC↑, PC↑, Mucositis↓, *AntiBio↑, *AntiViral↑, *AntiFungal↑, *Inflam↓,
8204- LGE,    Scientific basis for the therapeutic use of Cymbopogon citratus, stapf (Lemon grass)
- Review, Var, NA
*Dose↝, *Bacteria↓, *Diar↓, *AntiFungal↑, *Inflam↓,
8295- lign,    Distribution, biosynthesis and therapeutic potential of lignans
- Review, Var, NA
*Ingr?, *BioAv↝, *antiOx↑, *AntiCan↑, *Inflam↓, *other?, Dose↝, AntiTum↑, pS2/TFF1↓, Bcl-2↓, IGF-1R↓, *radioP↑, *HO-1↑, GSTM1↑, NQO1↑, ChemoSen↑, *AntiDiabetic↑, *glucose↓, *GSH↑, *SOD↑, *MDA↓, *NO↓, *Bacteria↓, *AntiFungal↑,
8311- lign,    The Power of Lignans: Plant Compounds with Multifaceted Health-Promoting Effects
- Review, Nor, NA
*cardioP↑, *AntiDiabetic↑, *Obesity↓, *Bacteria↓, *AntiFungal↑, *AntiViral↑, *neuroP↑, *antiOx↑, *lipid-P↓, *memory↑, *CREB↑, *BDNF↑, *PSD95↑, *β-Amyloid↓, *TNF-α↓, *IL6↓, *IL10↓, *GutMicro↑, *Endoglin↑, *END↑, *cognitive↑, *Akt↓, *IκB↓, *NF-kB↓, *HO-1↑, *VEGF↑, *p‑eNOS↑, *GRP78/BiP↓, *PERK↓, *ATF4↓, *CHOP/DDIT3↓, *SREBP1/SREBF1↓, *ROS↓, TumVol↓,
8912- MO,    Anticancer effect of Moringa oleifera in oral squamous cell carcinoma: a systematic review
- Review, Oral, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *chemoPv↑, *Ingr↝, *AntiDiabetic↑, *hepatoP↑, *Bacteria↓, *AntiFungal↑, Apoptosis↑, ROS↑, DNAdam↑, Casp3↑, TumCCA↑, ROS↓, chemoP↑,
6775- Neem,  Nimb,    Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment
- Review, Nor, NA
*antiOx↑, P53↑, PTEN↑, NF-kB↓, PI3K↓, Akt↓, Bcl-2↓, VEGF↓, *Inflam↓, *COX2/PTGS2↓, *5LO↝, *Wound Healing↑, *Imm↑, *hepatoP↑, *AntiDiabetic↑, *neuroP↑, *AntiViral↑, *Bacteria↑, *AntiBio↑, *AntiFungal↑, cMyc↓, BAX↓, IAP1↓, IAP2/BIRC3↓, Bcl-xL↓, survivin↓, XIAP↓, angioG↓,
8434- OM,    Traditional use, phytochemistry, toxicology, and pharmacology of Origanum majorana L
- Review, Var, NA
*Bacteria↓, *AntiFungal↑, *antiOx↑, *AntiP↑, *AntiDiabetic↑, *AntiCan↑, *RenoP↑, *Inflam↓, *Analgesic↑, *antiPy↑, *antiM↑, *Ingr↝, *Ingr↝, *creat↓, *Urea↓, *uricA↓, *BUN↓, *ALAT↓, *AST↓, *ALP↓, *Catalase↑, *SOD↑, *GSTA1↑,
8452- OM,    Sweet Marjoram: A Review of Ethnopharmacology, Phytochemistry, and Biological Activities
- Review, Nor, NA
*hepatoP↑, *cardioP↑, *AntiAg↑, *GastroP↑, *Bacteria↓, *AntiFungal↑, *Inflam↓, *TumMeta↓, *AntiTum↑, *AChE↓, *Ingr↝, *antiOx↑, Apoptosis↑, P53↑, Bcl-2↓, E-cadherin↑, MMP2↓, MMP9↓, TumMeta↓, *NO↓, *lipid-P↓,
6441- SAO,    Sandalwood Album Oil as a Botanical Therapeutic in Dermatology
- Review, PSA, NA
*Inflam↓, *eff↑, *5LO↓, *DPPH↓, *hepatoP↑, *ROS↓, *PGE2↓, *IL1β↓, *IL17↓, *PDE4↓, *tyrosinase↓, *AntiFungal↑, angioG↓, TumCG↓, DNAdam↑, *Snail↑, *Twist↑, *Vim↑, *EMT↓, *toxicity↓,
6768- T4O,    Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties
- Review, Nor, NA
*AntiBio↑, *other↝, *AntiFungal↑, *Inflam↓, *ROS⇅, *toxicity↑,
6776- TQ,    Black cumin (Nigella sativa) and its constituent (thymoquinone): a review on antimicrobial effects
- Review, Nor, NA
*AntiBio↑, *AntiViral↑, *AntiFungal↑, *antiAll↑,
6453- TUR,    Pharmacological Profile, Bioactivities, and Safety of Turmeric Oil
- Review, Var, NA - Review, AD, NA - Review, Park, NA
*Dose↝, *BioEnh↑, *BBB↑, *ROS↓, *GSH↑, *SOD↑, *GSR↑, *NO↓, *P450↓, OS↑, TumCG↓, *GutMicro↑, *Pain↓, *neuroP↑, *AChE↓, *BDNF↑, *Bacteria↓, *AntiFungal↑, *toxicity↓,

Showing Research Papers: 1 to 37 of 37

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 37

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx⇅, 1,   Catalase↓, 1,   GSH↓, 1,   GSH↑, 1,   GSTs↑, 1,   HO-1↓, 1,   HO-1↑, 1,   lipid-P↑, 2,   NQO1↓, 1,   NQO1↑, 1,   NRF2↓, 1,   ROS↓, 1,   ROS↑, 6,   SOD?, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MFN2↑, 1,   mtDam↑, 1,   OXPHOS↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   AMPK↑, 1,   ATP↓, 1,   GSK‐3β↑, 1,   PLA2↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis?, 1,   Apoptosis↑, 7,   Bak↓, 1,   BAX↓, 1,   BAX↑, 5,   Bcl-2↓, 7,   Bcl-xL↓, 2,   BID↑, 1,   Casp3↑, 6,   cl‑Casp3↑, 1,   cl‑Casp3⇅, 1,   Casp8↑, 1,   Casp9↑, 4,   cl‑Casp9↑, 1,   Cyt‑c↑, 4,   Fas↑, 1,   IAP1↓, 2,   IAP2/BIRC3↓, 1,   iNOS↓, 1,   p38↑, 1,   pS2/TFF1↓, 1,   survivin↓, 3,   XIAP↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 8,   EGFR↑, 1,   HER2/EBBR2↓, 1,   IGF-1R↓, 1,   JAK1↓, 1,   JNK↓, 1,   MAPK↓, 1,   MAPK↑, 1,   MAPK↝, 1,   mTOR↓, 4,   mTOR↝, 1,   P70S6K↓, 1,   PI3K↓, 3,   PTEN↑, 2,   SHP1↑, 1,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cMyc↓, 1,   FOXO1↑, 1,   other↑, 2,   other↝, 3,   tumCV↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3II↑, 2,   TumAuto↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 4,   P53↑, 4,   P53↝, 1,   PARP↑, 1,   cl‑PARP↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

Ki-67↓, 1,   TumCCA↓, 1,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP7/OP1↓, 1,   CSCs↓, 1,   FGF↓, 1,   Gli1↓, 1,   HH↓, 3,   Ki-67↓, 1,   Shh↓, 1,   Smo↓, 1,   TumCG↓, 2,   TumCP↓, 4,   Wnt↓, 2,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   E-cadherin↑, 1,   fascin↓, 1,   MMP2↓, 2,   MMP9↓, 3,   MMPs↓, 1,   SMAD2↓, 1,   TGF-β↓, 1,   TIMP2↑, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumMeta↓, 3,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 4,   HIF-1↓, 1,   LymphAG↓, 1,   VEGF↓, 2,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

EPR↑, 1,   MMP↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 4,   IL6↓, 2,   IL8↓, 1,   Imm↑, 2,   INF-γ↝, 1,   Inflam↓, 1,   Neut↑, 1,   NF-kB↓, 3,   NF-kB↑, 1,   PGE2↓, 1,   PSA↓, 1,   T-Cell↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos∅, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 2,   CYP2C9↓, 1,   CYP2D6↓, 1,   CYP2E1↓, 1,   Dose↝, 9,   eff↑, 6,   GSTM1↑, 1,   P-gp/ABCB1↓, 1,   RadioS↑, 1,   Synergy↑, 6,   UGT1A↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   BUN↓, 1,   CEA↓, 1,   creat↓, 1,   EGFR↑, 1,   HER2/EBBR2↓, 1,   IL6↓, 2,   PC↑, 1,   PSA↓, 1,   RBC↑, 1,   WBC↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 6,   antiNeop↑, 1,   AntiTum↑, 2,   chemoP↑, 1,   Mucositis↓, 2,   OS↑, 3,   Pin1↓, 1,   Risk↓, 2,   Risk↑, 1,   toxicity↓, 1,   toxicity↝, 1,   TumVol↓, 2,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   AntiViral↑, 1,   Bacteria↓, 1,  
Total Targets: 160

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 18,   ARE↑, 1,   Catalase↑, 5,   DPPH↓, 1,   GPx↑, 1,   GSH↑, 6,   GSR↑, 2,   H2O2↓, 1,   HO-1↑, 4,   Keap1↑, 1,   lipid-P↓, 7,   MDA↓, 4,   NRF2↑, 3,   ROS↓, 13,   ROS↑, 1,   ROS⇅, 1,   SOD↑, 7,   TAC↑, 2,   TBARS↓, 1,   uricA↓, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   5LO↝, 1,   ALAT↓, 1,   AMPK↑, 1,   ATP↑, 1,   FABP4↓, 1,   glucose↓, 2,   GSK‐3β↓, 2,   H2S↑, 1,   LDL↓, 1,   NADPH↑, 1,   SIRT1↑, 1,   SREBF2⇅, 1,   SREBP1/SREBF1↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 3,   BAX↓, 2,   Bcl-2↑, 1,   Casp3↓, 2,   Cyt‑c↓, 1,   iNOS↓, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 2,   AMPKα↑, 1,   CREB↑, 1,   ERK↓, 1,   IκB↓, 1,   MAPK↓, 1,   PDGFR-BB↓, 1,   PDGFRB↓, 1,   PKCδ↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   ATF4↓, 1,   HDAC↑, 1,   other?, 1,   other↑, 1,   other↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   GRP78/BiP↓, 1,   PERK↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

Telomerase↓, 1,   TOP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CEBPA↓, 1,   tyrosinase↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 2,   AntiAg↑, 4,   EMT↓, 1,   MMP13↓, 1,   Snail↑, 1,   TGF-β1↓, 1,   TumMeta↓, 1,   Twist↑, 1,   Tyro3↓, 1,   uPA↑, 1,   Vim↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Endoglin↑, 1,   p‑eNOS↑, 1,   NO↓, 5,   TXA2↓, 1,   VCAM-1↓, 1,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 5,   GastroP↑, 3,   memfluid↑, 1,   MMP↑, 1,   MUC19↓, 1,   MUC2↓, 1,   TRPA1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   CD8+↑, 1,   COX1↓, 1,   COX2/PTGS2↓, 3,   ICAM-1↓, 1,   IL10↓, 1,   IL10↑, 1,   IL17↓, 1,   IL1β↓, 6,   IL4↓, 1,   IL4↑, 1,   IL6↓, 7,   IL6↑, 1,   IL8↓, 1,   Imm↑, 3,   Imm↝, 1,   Inflam↓, 26,   MCP1/CCL2↓, 1,   NF-kB↓, 5,   NLRP3↓, 1,   PGE2↓, 4,   TNF-α↓, 6,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 7,   BChE↓, 3,   BDNF↑, 5,   MAOA↓, 1,   MAOB↓, 1,   NGF↑, 1,   PSD95↑, 1,   TrkB↑, 2,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   Aβ↓, 3,   BACE/β-secretase↓, 2,   tau↓, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

END↑, 1,   PPARγ↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 5,   BioAv↝, 3,   BioEnh↑, 1,   ChemoSen↑, 1,   CYP2D6↓, 1,   Dose↝, 3,   eff↑, 3,   GSTA1↑, 1,   Half-Life↑, 1,   Half-Life↝, 2,   P450↓, 2,   Synergy↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   BMD↑, 1,   BP↓, 1,   BUN↓, 1,   creat↓, 2,   IL6↓, 7,   IL6↑, 1,   TMAO↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 2,   AntiAge↑, 1,   antiAll↑, 3,   AntiArt↑, 1,   AntiCan↓, 1,   AntiCan↑, 5,   antiCG↑, 1,   AntiDiabetic↑, 12,   antiM↑, 1,   antiPy↑, 1,   AntiTum↑, 1,   Bone Healing↑, 1,   cardioP↑, 10,   chemoP↑, 2,   chemoPv↑, 1,   cognitive↑, 4,   hepatoP↑, 11,   memory↑, 3,   motorD↑, 1,   neuroP↑, 13,   Obesity↓, 4,   Pain↓, 3,   PDE4↓, 1,   radioP↑, 2,   RenoP↑, 4,   Stroke↓, 3,   toxicity↓, 9,   toxicity↑, 1,   Wound Healing↑, 4,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 11,   AntiFungal↓, 2,   AntiFungal↑, 34,   AntiP↑, 2,   AntiViral↑, 10,   Bacteria↓, 18,   Bacteria↑, 1,   Diar↓, 3,   GutMicro↑, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 1,   Ingr↝, 4,  
Total Targets: 190

Scientific Paper Hit Count for: AntiFungal, AntiFungal
4 itraconazole
2 1,8-Cineole
2 Silver-NanoParticles
2 flavonoids
2 SDG/lignans
2 Marjoram (Origanum majorana)
1 Allicin (mainly Garlic)
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 DTS(dibenzyl trisulphide) from Anamu
1 α-Bisabolol / Chamomile oil
1 Centella asiatica / Gotu kola → asiaticoside
1 Cinnamon
1 Carvone
1 Diindolylmethane
1 Indole-3-carbinol
1 Eugenol
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Ginkgetin
1 Hyperoside
1 Isobavachalcone
1 Juglone
1 Kaempferol
1 Licochalcone A
1 Lactoferrin/Talactoferrin
1 Lemongrass Extract/Citral
1 Moringa oleifera
1 Neem
1 Nimbolide
1 α-Santalol/Sandalwood oil
1 Terpinen-4-ol / Tea Tree Oil
1 Thymoquinone
1 Turmerones
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1382  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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