AntiArt Cancer Research Results

AntiArt, AntiArthritis: Click to Expand ⟱
Source:
Type:
AntiArthritis
Scientific Papers found: Click to Expand⟱
7402- Amla,    Traditional knowledge to clinical trials: A review on therapeutic actions of Emblica officinalis
- Review, Var, NA
*Synergy↑, *antiOx↑, *AntiCan↑, *Imm↑, *Inflam↓, *AntiArt↑, *Dose↝, *VitC↑, radioP↑, *cardioP↑, *GastroP↑, *Wound Healing↑, *Diar↓, eff↑, NK cell↑, BAX↑, Bcl-2↓, TumCCA↑, Dose↝,
2775- Bos,    The journey of boswellic acids from synthesis to pharmacological activities
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
ROS↑, ER Stress↑, TumCG↓, Apoptosis↑, Inflam↓, ChemoSen↑, Casp↑, ERK↓, cl‑PARP↑, AR↓, cycD1/CCND1↓, VEGFR2/KDR/Flk1↓, CXCR4↓, radioP↑, NF-kB↓, VEGF↓, P21↑, Wnt↓, β-catenin/ZEB1↓, Cyt‑c↑, MMP2↓, MMP1↓, MMP9↓, PI3K↓, MAPK↓, JNK↑, *5LO↓, *NRF2↑, *HO-1↑, *MDA↓, *SOD↑, *hepatoP↑, *ALAT↓, *AST↓, *LDH↑, *CRP↓, *COX2/PTGS2↓, *GSH↑, *ROS↓, *Imm↑, *Dose↝, *eff↑, *neuroP↑, *cognitive↑, *IL6↓, *TNF-α↓, *AntiArt↑, *AntiDiabetic↑, *antiAll↑,
6135- CHr,    Chrysin as a Multifunctional Therapeutic Flavonoid: Emerging Insights in Pathogenesis Management: A Narrative Review
- Review, Var, NA - Review, AD, NA
Inflam↓, angioG↓, Apoptosis↑, TumAuto↑, TumCCA↑, BioAv↓, Half-Life↓, BioAv↓, *ROS↓, *hepatoP↑, *RenoP↑, TET1↑, MMP9↓, cMyc↓, Ki-67↓, CBR1↓, ROS↑, ChemoSen↑, Bax:Bcl2↑, PUMA↑, NOTCH1↑, *AntiDiabetic↑, *neuroP↑, *GABA↑, *DNAdam↓, *BDNF↑, *memory↑, *AGEs↓, *Aβ↓, *cardioP↑, *AntiArt↑, Synergy↑, Synergy↑, *Synergy↑, RadioS↑, Synergy↑, ChemoSen↑, eff↑,
6520- CRV,    Health Benefits and Pharmacological Properties of Carvone
- Review, Nor, NA
*Bacteria↓, *AntiFungal↑, *antiOx↑, *Inflam↓, AntiCan↑, *AntiDiabetic↑, *Obesity↓, TumCCA↑, *AntiArt↑, Imm↑, *P450↓, *GSR↑, GSTs↑, GSH↑, BAX↑, Casp3↑, TumCP↓, TumCMig↓, Apoptosis↑,
6525- CRV,    D-carvone induced ROS mediated apoptotic cell death in human leukemic cell lines (Molt-4)
- in-vitro, AML, NA
tumCV↓, ROS↑, antiOx↓, MMP↓, Apoptosis↑, Casp8↑, Casp9↑, Casp3↑, *neuroP↑, AntiCan↑, *AntiArt↑, TBARS↑, SOD↓, GSH↓, Catalase↓,
6687- DFC,    Diclofenac-containing medicines - referral
- Review, Nor, NA
*Pain↓, *Inflam↓, *AntiArt↑, *cardioP↓,
6663- DFE,    Nutraceuticals of Phoenix dactylifera L.: Physicochemistry, Nutritional Value and Therapeutic Potential
- Review, Nor, NA - Review, AD, NA
*antiOx↑, *Inflam↓, *AntiBio↑, *AntiDiabetic↑, *AntiCan↑, *AntiArt↑, *neuroP↑, *hepatoP↑, *GastroP↑, *other↝, *cardioP↑, *cognitive↑, *ROS↓, *memory↑, *other↝, *SOD↑, *Catalase↑, *GSH↑, *GA↑, *Catechins↑, *FA↑, *QC↑, Api↑, *CA↑, *Imm↑, *Phen↑, *IL1β↓, *TGF-β↓, *COX1↓, *COX2/PTGS2↓, TumCP↓, Casp3↑, TumMeta↓, *GutMicro↑,
6366- DRE,    A comprehensive review of the benefits of Taraxacum officinale on human health
- Review, Var, NA
*diuretic↑, *hepatoP↑, *Imm↑, *Bacteria↓, *AntiArt↑, *AntiDiabetic↑, *Obesity↓, *antiOx↓, *AntiCan↑, Dose?,
6634- Ech,    Echinacea purpurea: Pharmacology, phytochemistry and analysis methods
- Review, Var, NA
AntiArt↑, *Imm↑, *Neut↑, *NK cell↑, *COX1↓, *COX2/PTGS2↓, *Inflam↓, TumCG↑, *toxicity↓,
6827- EMD,    Mechanism of Emodin in the Treatment of Rheumatoid Arthritis
- Review, Arthritis, NA
*ALAT↓, *AST↓, *ROS↓, *cardioP↑, *TNF-α↓, *NF-kB↓, *Inflam↓, *AntiArt↑, *PGE2↓, *MMP3↓, *MMP13↓, *COX2/PTGS2↓, *AntiCan↑, *neuroP↑, *hepatoP↑, *antiAll↑,
6355- Eug,    Pharmacological and Toxicological Properties of Eugenol
- Review, Var, NA
*Inflam↓, *antiOx↑, *NF-kB↓, *AntiArt↑, *lipid-P↓, *GSH↑, ROS↑, GSH↓, ChemoSen↑, Apoptosis↑, MMP↓, TumCG↓, TumCCA↑,
6388- Eug,    Eugenol’s anti-cancer properties, its modulation of signalling pathways, and cascades across various cancers: A review
- Review, Var, NA
Dose↝, AntiCan↑, *Inflam↓, *cardioP↑, *neuroP↑, angioG↓, TumMeta↓, *BioAv↑, *CompStab↑, *toxicity↝, antiNeop↑, TumCCA↑, Apoptosis↑, *antiOx↑, *lipid-P↓, *ROS↓, *SOD↑, *Catalase↑, *GSTs↑, *GPx↑, *iNOS↓, *COX2/PTGS2↓, *IL6↓, *TNF-α↓, *AntiArt↑, *Bacteria↓, TumAuto↑, PI3K↓, Akt↓, FOXO3↝, BAX↑, mTOR↓, NF-kB↓, P53↑, TumCG↓, CSCs↓, CD44↓, EpCAM↓, NOTCH1↓, OCT4↓, Bcl-2↓, PDK1 / PDPK1↓, HER2/EBBR2↓, BAD↓, cycD1/CCND1↓, ROS↑, Casp3↑, selectivity↑, MMP2↓, MMP9↓, TIMP1↑, VEGF↓, VEGFR1↓, RECK↑, TIMP2↑, DNAdam↑, MMP↓, Thiols↓, PARP↑, *Pain↓, E2Fs↓, survivin↓,
6323- Eug,    Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects
- Review, Var, NA - Review, Arthritis, NA
*AntiCan↑, *AntiDiabetic↑, *cardioP↑, *toxicity↝, *GutMicro↑, *neuroP↑, *BioAv⇅, *BioAv↝, *antiOx↑, *Inflam↑, *AntiArt↑, *TNF-α↓, *IL6↓, *IL10↓, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TAC↑, TumCMig↓, TumCI↓, Akt↑, FOXO3↑, Casp3↑, Casp9↑, P21↑, angioG↓, TumCI↓, Apoptosis↑, NF-kB↓, Synergy↑, Synergy↑, ChemoSen↑, NA↑, Casp3↑, Casp9↑, *AntiDiabetic↑, *glucose↓, *ROS↓, *Inflam↓, *MDA↓, *GSH↑, *BioAv↑,
8584- FS,    Anti-Oxidant and Anti-Cancer Properties of Flaxseed
- Review, Nor, NA
*Ingr↝, *cardioP↑, *LDL↓, *lipidLev↓, *AntiDiabetic↑, *hepatoP↑, *AntiCan↑, *Analgesic↑, *AntiArt↑, *CRP↓, *TNF-α↓, *Inflam↓, *toxicity↝, *neuroP↑, *Ingr↝, *Ingr↝, *AntiViral↑, Risk↓, *Ingr↝, *hs-CRP↓, *GutMicro↑, *TJ↑, *OCLN↝, *MLC2/MYL9↝, *VCAM-1↓, *Akt2↓, *IKKα↓, *NF-kB↓, Synergy↑, HER2/EBBR2↓, MAPK↓, PI3K↓, Akt↓, EGFR↓, TumCG↓, TumMeta↓, IGF-1↓, COX2/PTGS2↓, PGE2↓, CDK4↓, TNF-α↓, IL1β↓, lipid-P↑, P53↑, MDM2↑, cl‑Casp3↑, cl‑PARP↑, cl‑Casp7↑, BAX↑, Bcl-2↓, Bax:Bcl2↑, Cyt‑c↑, Casp9↑, Ki-67↓, CYP1A1↑, p38↑, ERK↑, Synergy↑, ChemoSen↑, *BioAv↑, eff↝, Ingr↝,
7067- GamB,    Gambogic Acid and Its Role in Chronic Diseases
- Review, Var, NA
*NF-kB↓, PI3K↓, Akt↓, STAT3↓, STAT5↓, IL6↓, COX2/PTGS2↓, iNOS↓, MMPs↓, Src↓, PKA↓, CXCR4↑, VEGF↓, Bcl-2↓, Bcl-xL↓, IAP1↓, Mcl-1↓, survivin↓, cycD1/CCND1↓, HSP90↓, HSP70/HSPA5↓, MAPK↓, HATs↓, HDAC↓, FAK↓, ROS↑, MMP7↓, MMP9↓, α-tubulin↑, cl‑PARP↑, TNF-α↓, BID↑, BAD↑, Cyt‑c↑, Casp3↑, Casp9↑, *AntiArt↑, *antiPs↑,
7567- HYP,    Hyperoside: A review on its sources, biological activities, and molecular mechanisms
- Review, Var, NA
*AntiCan↑, *Bacteria↓, *AntiViral↑, *antiD↓, *RenoP↑, *hepatoP↑, *eff↑, *Sepsis↓, *AntiArt↑, *Stroke↓, TumCMig↓, TumCI↓, MTA1↓, TIMP2↓, MMP2↓, MMP↓, Cyt‑c↑, Akt↓, mTOR↓, P70S6K↓, TumAuto↑, PD-L1↓, TNF-α↓, IL1β↓, IL6↓, IL8↓, Bcl-2↓, Bcl-xL↓, BAX↑, BAD↑, Bak↑, VEGF↓, Casp3↑, Casp8↑, P53↑, GSH↓, SOD↓, Catalase↓, TAC↓, XIAP↓, ROS↓, NF-kB↓, TLR4↓, P-gp/ABCB1↓, LRP1↓, Fas↑, p27/CDKN1B↑, *cardioP↑, *AntiThr↑, *PAI-1/SERPINE1↓, *BUN↓, *ALAT↓, *AST↓, *neuroP?,
7763- ISL,    Harnessing Liquiritigenin: A Flavonoid-Based Approach for the Prevention and Treatment of Cancer
- Review, Var, NA
AntiCan↑, *antiOx↓, *Inflam↓, TumCP↓, Apoptosis↑, NF-kB↓, PI3K↓, Akt↓, mTOR↓, *AntiArt↑, Casp8↑, Cyt‑c↑, Casp↑, cl‑PARP↑, GutMicro↑, BioAv↑, BioAv↓, Half-Life↓,
8163- LapC,    Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis
- in-vivo, Arthritis, NA
*DHODH↓, *Imm↓, AntiArt↑, antiPs↑, BioAv↝,
8237- LCA,    Role of Licochalcone A in Potential Pharmacological Therapy: A Review
- Review, Var, NA
*other↝, *Inflam↓, *Bacteria↓, *antiOx↑, *AntiP↑, *neuroP↑, *glucose↝, *lipid-P↓, PKCδ↓, P70S6K↓, Akt↓, ER Stress↑, Apoptosis↑, Ca+2↑, PI3K↓, mTOR↓, Casp3↑, Bcl-2↓, Cyt‑c↑, BAX↑, cl‑PARP↑, cycD1/CCND1↑, ROS↑, CHOP/DDIT3↑, ERK↑, p38↑, JNK↓, IAP1↓, XIAP↓, survivin↓, cFLIP↓, RIP1↓, EGFR↓, MET↓, HER2/EBBR2↓, p‑4E-BP1↓, PERK↑, eIF2α↑, PD-L1↓, HK2↓, Glycolysis↓, Sp1/3/4↓, FasL↑, MMP↓, ATP↓, TumAuto↑, WEE1↑, P21↑, CDK1↓, TumCCA↑, TumCMig↓, TumCI↓, ABCG2↓, HSP90↓, T-Cell↑, CD4+↑, CD25+↑, FOXP3↑, Imm↝, *Inflam↓, *NF-kB↓, *NRF2↑, *AntiArt↑, *antiAll↑, *MUC5AC↓, *E-sel↓, *CCL11↓,
8246- LCA,    Licochalcone A activates Keap1-Nrf2 signaling to suppress arthritis via phosphorylation of p62 at serine 349
- in-vivo, Arthritis, NA
*AntiBio↑, *AntiTum↑, *Inflam↓, *AntiArt↑, *p62↑, *NRF2↑,
8414- Lyco,    Exploring the Therapeutic Potential of Lycopene: Mechanisms, Biological Activities, and Health Benefits
- Review, Var, NA - Review, AD, NA
*ROS↓, *Inflam↓, *hepatoP↑, *cardioP↑, *neuroP↑, *AntiArt↑, *Obesity↓, *Wound Healing↑, *BioAv↑, *GSTs↑, *Trx1↑, *SOD↑, *Catalase↑, *ALAT↓, *LDH↓, *AST↓, *MDA↓, *cognitive↑, *memory↑, *NeuroI↓, *Aβ↓, *LRP1↑, *RAGE↓, *NRF2↑, *HO-1↑, tumCV?, Bax:Bcl2↑, DNAdam↑, Apoptosis↑, β-catenin/ZEB1↓, cMyc↓, cycD1/CCND1↓, ROS↓, TumCCA↑, Akt↓, *Synergy↑, *MDA↓, *NF-kB↓, *TGF-β↓, *Casp3↓, *Catalase↑, *GSH↑, *Bcl-2↑, *IL10↑, *MUC1↑, *IBI↑, *RenoP↑, *ChemoSen↑, *Synergy↑, *Synergy↑, *BMD↑,
8526- Matr,    A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine
- Review, Nor, NA
*AntiCan↑, *Inflam↓, *antiOx↑, *AntiViral↑, *Bacteria↓, *antiAll↑, *Analgesic↑, *hepatoP↑, *cardioP↑, *neuroP↑, *toxicity↝, p38↓, IL6↓, JAK2↓, STAT3↓, Casp↑, PI3K↓, Akt↓, mTOR↓, Beclin-1/ATG6↑, PCNA↓, Bcl-2↓, XIAP↑, VEGF↓, NF-kB↓, MMP2↓, MMP9↓, P-gp/ABCB1↓, survivin↓, OCT4↓, SOX2↓, p62↓, *TNF-α↓, *IL6↓, *HMGB1↓, *AntiArt↑, *NF-kB↓, *IL6↓, *IL8↓, *IL1β↓, *IL17↓, *TNF-α↓, *ROS↓, *NRF2?, *AST↓, *ALAT↓, *TGF-β↓, *α-SMA↓, *JAK2↑, *STAT3↑, *BioAv↝, *Half-Life↝, ChemoSen↑, ATP↓, ROS↑,
8560- Matr,    Matrine: A Promising Natural Product With Various Pharmacological Activities
- Review, AD, NA - Review, Stroke, NA - Review, Var, NA
*antiAll↑, *Stroke↓, *AntiArt↑, TumCCA↑, VEGF↓, Apoptosis↑, P53↑, P21↑, PCNA↓, EIF4E↓, TumCP↓, TumCMig↓, IAP1↓, ROS↑, EMT↓, PAX2↓, ER Stress↑, HK2↓, Apoptosis↑, STAT3↓, mtDam↑, HMGB1↓, ChemoSen↑, p‑GSK‐3β↓, P-gp/ABCB1↓, MRP1/ABCC1↓, Vim↓, cycD1/CCND1↓, CDK4↓, GSH↓, SOD↓, mt-Cyt‑c↓, BAX↑, MMP9↓, MMP2↓, E-cadherin↓, N-cadherin↓, FOXO1↓, FOXO3↓, FOXO4↓, PI3K↓, ATF4↑, CHOP/DDIT3↑, *Aβ↓, *RAGE↓, *memory↑, *Learn↑, *cognitive↑, *MDA↓, *SOD↑, *GPx↑, *Catalase↑, *antiAll↑, *AHR↓, *SOCS-3↓, *ICAM-1↓, *ROS↓, cachexia↓, *BACE/β-secretase↓, *NF-kB↓, *TNF-α↓, *IL1β↓,
8775- MSM,    Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells
- Review, Colon, HCT116
*AntiArt↑, *ROS↓, tumCV↓, Apoptosis↑, PARP↑, Casp3↑, p‑JNK↑, eff↝, *toxicity↓, ChemoSen↑, TumCP↓,
6486- Nimb,    Nimbolide: promising agent for prevention and treatment of chronic diseases
- Review, Var, NA - Review, AD, NA
*other↝, *Inflam↓, AntiCan↑, *Bacteria↓, *AntiViral↑, *neuroP↑, *hepatoP↑, *ROS?, *NRF2↑, *HO-1↑, *TLR4↓, *NF-kB↓, *AChE↓, *Aβ↓, *GSK‐3β↓, *LDL↓, *DNAdam↓, *lipid-P↓, *antiOx↑, *SOD1↑, *GSH↑, *IL6↓, *IL1β↓, *STAT3↓, *GPx↑, *Catalase↑, *MDA↓, *AntiDiabetic↑, *HDL↓, *MCP1/CCL2↓, *VEGF↓, *MMP9↓, *GutMicro↑, TumCP↓, TumCCA↑, TumCMig↓, NF-kB↓, ROS↑, PI3K↓, Akt↓, mTOR↓, ERK↓, EMT↓, TumMeta↓, ChemoSen↑, eff↑, selectivity↑, CDK4↓, CDK6↓, Wnt↓, β-catenin/ZEB1↓, STAT3↓, MMP2↓, Sp1/3/4↓, AP-1↓, P21↑, *AntiArt↑, *IL23↓, *IL17↓, *IFN-γ↓, *HSP70/HSPA5↓,
7533- OLE,  HT,    Systemic Health Effects of Oleuropein and Hydroxytyrosol Supplementation: A Systematic Review of Randomized Controlled Trials
- Review, Nor, NA
*Weight↝, *cognitive↑, *AntiArt↑, *Dose↝, *Dose↝, *Dose↝,
7954- RT,    Rutin : therapeutic potential and recent advances in drug delivery
- Review, Nor, NA - Review, IBD, NA
*antiOx↑, *antiAll↑, *Inflam↓, *AntiTum↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *AntiArt↑, *PLA2↓, *chemoP↑, *ROS↓, *Casp3↓, *TNF-α↓, *NF-kB↓, *cardioP↑, *Stroke↓, *TG/TAG↓, *FFA/NEFA↓, *LDL↓, *HDL↑, *AntiDiabetic↑, *MPO↓, *NF-kB↓, *BioAv↓, *BioAv↝,

Showing Research Papers: 1 to 27 of 27

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 27

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   Catalase↓, 2,   GSH↓, 4,   GSH↑, 1,   GSTs↑, 1,   lipid-P↑, 1,   ROS↓, 2,   ROS↑, 10,   SOD↓, 3,   TAC↓, 1,   TBARS↑, 1,   Thiols↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

mtDam↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ATP↓, 2,   Glycolysis↓, 1,   p‑GSK‐3β↓, 1,   HK2↓, 2,   PDK1 / PDPK1↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 13,   BAD↓, 1,   BAD↑, 2,   Bak↑, 1,   BAX↑, 7,   Bax:Bcl2↑, 3,   Bcl-2↓, 7,   Bcl-xL↓, 2,   BID↑, 1,   Casp↑, 3,   Casp3↑, 10,   cl‑Casp3↑, 1,   cl‑Casp7↑, 1,   Casp8↑, 3,   Casp9↑, 5,   cFLIP↓, 1,   Cyt‑c↑, 6,   mt-Cyt‑c↓, 1,   Fas↑, 1,   FasL↑, 1,   IAP1↓, 3,   iNOS↓, 1,   Mcl-1↓, 1,   MDM2↑, 1,   p38↓, 1,   p38↑, 2,   PUMA↑, 1,   RIP1↓, 1,   survivin↓, 4,   XIAP↓, 2,   XIAP↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 9,   Akt↑, 1,   EGFR↓, 2,   ERK↓, 2,   ERK↑, 2,   HER2/EBBR2↓, 3,   JAK2↓, 1,   JNK↓, 1,   JNK↑, 1,   p‑JNK↑, 1,   MAPK↓, 3,   mTOR↓, 6,   P70S6K↓, 2,   PI3K↓, 9,   PKA↓, 1,   PKCδ↓, 1,   Sp1/3/4↓, 2,   Src↓, 1,   STAT3↓, 4,   STAT5↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   cMyc↓, 2,   FOXO1↓, 1,   FOXO3↓, 1,   FOXO3↑, 1,   FOXO3↝, 1,   FOXO4↓, 1,   HATs↓, 1,   HDAC↓, 1,   OCT4↓, 2,   PAX2↓, 1,   SOX2↓, 1,   tumCV?, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 2,   eIF2α↑, 1,   ER Stress↑, 3,   HSP70/HSPA5↓, 1,   HSP90↓, 2,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   p62↓, 1,   TumAuto↑, 4,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,   P53↑, 4,   PARP↑, 2,   cl‑PARP↑, 5,   PCNA↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK4↓, 3,   CDK6↓, 1,   cycD1/CCND1↓, 5,   cycD1/CCND1↑, 1,   E2Fs↓, 1,   Ki-67↓, 2,   P21↑, 5,   p27/CDKN1B↑, 1,   TumCCA↑, 9,   WEE1↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑4E-BP1↓, 1,   CSCs↓, 1,   EIF4E↓, 1,   IGF-1↓, 1,   Ki-67↓, 2,   NOTCH1↓, 1,   NOTCH1↑, 1,   TumCG↓, 4,   TumCG↑, 1,   TumCP↓, 6,   Wnt↓, 2,  

Migration(tgid=13) ⓘ

AP-1↓, 1,   Ca+2↑, 1,   E-cadherin↓, 1,   EMT↓, 2,   EpCAM↓, 1,   FAK↓, 1,   LRP1↓, 1,   MET↓, 1,   MMP1↓, 1,   MMP2↓, 6,   MMP7↓, 1,   MMP9↓, 6,   MMPs↓, 1,   MTA1↓, 1,   N-cadherin↓, 1,   RECK↑, 1,   TET1↑, 1,   TIMP1↑, 1,   TIMP2↓, 1,   TIMP2↑, 1,   TumCI↓, 4,   TumCMig↓, 6,   TumMeta↓, 4,   Vim↓, 1,   α-tubulin↑, 1,   β-catenin/ZEB1↓, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 3,   VEGF↓, 6,   VEGFR1↓, 1,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

MMP↓, 5,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD25+↑, 1,   CD4+↑, 1,   CD44↓, 1,   COX2/PTGS2↓, 2,   CXCR4↓, 1,   CXCR4↑, 1,   FOXP3↑, 1,   HMGB1↓, 1,   IL1β↓, 2,   IL6↓, 3,   IL8↓, 1,   Imm↑, 1,   Imm↝, 1,   Inflam↓, 2,   NF-kB↓, 7,   NK cell↑, 1,   PD-L1↓, 2,   PGE2↓, 1,   T-Cell↑, 1,   TLR4↓, 1,   TNF-α↓, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 3,   BioAv↑, 1,   BioAv↝, 1,   CBR1↓, 1,   ChemoSen↑, 10,   CYP1A1↑, 1,   Dose?, 1,   Dose↝, 2,   eff↑, 3,   eff↝, 2,   Half-Life↓, 2,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 3,   RadioS↑, 1,   selectivity↑, 2,   Synergy↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   EGFR↓, 2,   HER2/EBBR2↓, 3,   IL6↓, 3,   PD-L1↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiArt↑, 2,   AntiCan↑, 5,   antiNeop↑, 1,   antiPs↑, 1,   cachexia↓, 1,   radioP↑, 2,   Risk↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,   Ingr↝, 1,  
Total Targets: 205

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 10,   Catalase↑, 7,   GPx↑, 4,   GSH↑, 7,   GSR↑, 1,   GSTs↑, 2,   HDL↓, 1,   HDL↑, 1,   HO-1↑, 3,   lipid-P↓, 4,   MDA↓, 7,   MPO↓, 1,   NRF2?, 1,   NRF2↑, 5,   ROS?, 1,   ROS↓, 11,   SOD↑, 5,   SOD1↑, 1,   TAC↑, 1,   Trx1↑, 1,   VitC↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   ALAT↓, 5,   DHODH↓, 1,   FFA/NEFA↓, 1,   glucose↓, 1,   glucose↝, 1,   GSK‐3β↓, 1,   LDL↓, 3,   lipidLev↓, 1,   PLA2↓, 1,  

Cell Death(tgid=5) ⓘ

Bcl-2↑, 1,   Casp3↓, 2,   iNOS↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt2↓, 1,   IKKα↓, 1,   JAK2↑, 1,   STAT3↓, 1,   STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   other↝, 4,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP70/HSPA5↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,  

Migration(tgid=13) ⓘ

LRP1↑, 1,   MLC2/MYL9↝, 1,   MMP13↓, 1,   MMP3↓, 1,   MMP9↓, 1,   MUC1↑, 1,   PAI-1/SERPINE1↓, 1,   TGF-β↓, 3,   α-SMA↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

E-sel↓, 1,   VCAM-1↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GastroP↑, 2,   IBI↑, 1,   MUC5AC↓, 1,   OCLN↝, 1,   TJ↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCL11↓, 1,   COX1↓, 2,   COX2/PTGS2↓, 5,   HMGB1↓, 1,   ICAM-1↓, 1,   IFN-γ↓, 1,   IL10↓, 1,   IL10↑, 1,   IL17↓, 2,   IL1β↓, 4,   IL23↓, 1,   IL6↓, 6,   IL8↓, 1,   Imm↓, 1,   Imm↑, 5,   Inflam↓, 18,   Inflam↑, 1,   MCP1/CCL2↓, 1,   NeuroI↓, 1,   Neut↑, 1,   NF-kB↓, 11,   NK cell↑, 1,   PGE2↓, 1,   RAGE↓, 2,   SOCS-3↓, 1,   TLR4↓, 1,   TNF-α↓, 9,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BDNF↑, 1,   GABA↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   Aβ↓, 4,   BACE/β-secretase↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 4,   BioAv⇅, 1,   BioAv↝, 3,   ChemoSen↑, 1,   CompStab↑, 1,   Dose↝, 5,   eff↑, 2,   Half-Life↝, 1,   P450↓, 1,   Synergy↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 5,   AST↓, 5,   BMD↑, 1,   BUN↓, 1,   CRP↓, 2,   hs-CRP↓, 1,   IL6↓, 6,   LDH↓, 1,   LDH↑, 1,   RAGE↓, 2,   TG/TAG↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 2,   antiAll↑, 7,   AntiArt↑, 25,   AntiCan↑, 8,   antiD↓, 1,   AntiDiabetic↑, 10,   antiPs↑, 1,   AntiTum↑, 2,   cardioP↓, 1,   cardioP↑, 11,   chemoP↑, 1,   cognitive↑, 5,   diuretic↑, 1,   hepatoP↑, 10,   Learn↑, 1,   memory↑, 4,   neuroP?, 1,   neuroP↑, 12,   Obesity↓, 3,   Pain↓, 2,   RenoP↑, 3,   Stroke↓, 3,   toxicity↓, 2,   toxicity↝, 4,   Weight↝, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 2,   AntiFungal↑, 1,   AntiP↑, 1,   AntiViral↑, 5,   Bacteria↓, 8,   Diar↓, 1,   GutMicro↑, 4,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

CA↑, 1,   Catechins↑, 1,   FA↑, 1,   GA↑, 1,   Ingr↝, 4,   Phen↑, 1,   QC↑, 1,  
Total Targets: 159

Scientific Paper Hit Count for: AntiArt, AntiArthritis
3 Eugenol
2 Carvone
2 Licochalcone A
2 Matrine
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Boswellia (frankincense)
1 Chrysin
1 Diclofenac
1 Date Fruit Extract
1 Dandelion Root
1 Echinacea
1 Emodin
1 Flaxseed/Linseed
1 Gambogic Acid
1 Hyperoside
1 Isoliquiritigenin
1 Lapachol
1 Lycopene
1 Methylsulfonylmethane
1 Nimbolide
1 Oleuropein
1 HydroxyTyrosol
1 Rutin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1471  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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