SOX18 Cancer Research Results

SOX18, : Click to Expand ⟱
Source:
Type:

SOX18 - SRY-Box Transcription Factor 18
Abbreviation: SOX18
Type: Transcription factor
Function: Regulates endothelial differentiation, angiogenesis, lymphangiogenesis, vascular development, and endothelial tight-junction genes including CLDN5 (claudin-5). SOX18 can promote tumor vascularization, proliferation, EMT, invasion, and metastasis.
Cancer: ↑ Typically increased / pro-tumorigenic; inhibition or knockdown can reduce angiogenesis, invasion, and metastasis.
Scientific Papers found: Click to Expand⟱
7230- EGb 761,    Ginkgo biloba extract (EGb 761) promotes peripheral nerve regeneration and neovascularization after acellular nerve allografts in a rat model
- in-vivo, Nor, NA
*Dose↝, *NGF↑, *angioG↑, *VEGF↑, *SOX18↑, *CD133↑, *IL6↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   SOX18↑, 1,   VEGF↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL6↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

NGF↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

IL6↑, 1,  
Total Targets: 8

Scientific Paper Hit Count for: SOX18, 
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1613  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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