Learn Cancer Research Results

Learn, Learning: Click to Expand ⟱
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Learning ability



Scientific Papers found: Click to Expand⟱
7516- CA,    Caffeic Acid, a Polyphenolic Micronutrient Rescues Mice Brains against Aβ-Induced Neurodegeneration and Memory Impairment
- in-vivo, AD, NA
*neuroP↑, *antiOx↑, *memory↑, *Learn↑, *cognitive↑, *ROS↓, *lipid-P↓, *NRF2↑, *HO-1↑, *Aβ↓, *BACE/β-secretase↓,
7520- CAPE,    Neuroprotective Effect of Caffeic Acid Phenethyl Ester in A Mouse Model of Alzheimer's Disease Involves Nrf2/HO-1 Pathway
- in-vivo, AD, NA
*ROS↓, *NRF2↑, *HO-1↑, *Apoptosis↓, *Inflam↓, *Learn↑, *memory↑, *cognitive↑, *neuroP↑, *p‑GSK‐3β↓, GFAP↓,
7522- DFE,    Diet rich in date palm fruits improves memory, learning and reduces beta amyloid in transgenic mouse model of Alzheimer's disease
- in-vivo, AD, NA
*Aβ↓, *neuroP↑, *motorD↑, *memory↑, *Learn↑,
7530- HT,    The Impact of Hydroxytyrosol on the Metallomic-Profile in an Animal Model of Alzheimer's Disease
- in-vivo, AD, NA
*Learn↑, *Copper↓,
7566- HYP,    Hyperoside improves learning and memory deficits by amyloid β1-42 in mice through regulating synaptic calcium-permeable AMPA receptors
- in-vivo, AD, NA
*Learn↑, *memory↑, *Aβ↓,
7544- HYP,    Long-term oral administration of hyperoside ameliorates AD-related neuropathology and improves cognitive impairment in APP/PS1 transgenic mice
- in-vivo, AD, NA
*Learn↑, *memory↑, *Aβ↓, *p‑tau↓, *Inflam↓, *ROS↓, *BACE/β-secretase↓, *GSK‐3β↓,
7759- ISL,  Rad,    Isoliquiritigenin, a Bioactive Blood Component Derived from Licorice, Activates Nrf2 Enzymes to Confer Protection Against Radiation-Induced Nerve Injury
- vitro+vivo, Nor, PC12
*radioP↑, *LDH↓, *ROS↓, *SOD1↑, *GSH↑, *TAC↑, *NRF2↓, *cognitive↑, *Learn↑, *memory↑,
7784- ISL,    Isoliquiritigenin attenuates lipopolysaccharide-induced cognitive impairment through antioxidant and anti-inflammatory activity
- in-vivo, AD, NA
*Learn↑, *PSD95↑, *BDNF↑, *SOD↑, *GPx↑, *Bcl-2↑, *SYP↑, *Bax:Bcl2↓, *TNF-α↓, *IL1β↓, *IL6↓, *MIP‑1α/CCL3↓, *p‑GSK‐3β↑, *NRF2↑, *HO-1↑, *NQO1↑, *cognitive↑, *Inflam↓,
7821- ISQ,    Quercitrin improved cognitive impairment through inhibiting inflammation induced by microglia in Alzheimer's disease mice
- in-vivo, AD, NA
*cognitive↑, *Inflam↓, *Aβ↓, *neuroP↑, *memory↑, *Learn↑,
7799- ISQ,    Acer okamotoanum and isoquercitrin improve cognitive function via attenuation of oxidative stress in high fat diet- and amyloid beta-induced mice
- in-vivo, AD, NA
*cognitive↑, *Learn↑, *memory↓, *ROS↓, *lipid-P↓, *NO↓,
8084- KAE,    Kaempferol treatment ameliorates memory impairments in STZ‑induced neurodegeneration by acting on reelin signaling
- in-vivo, AD, NA
*Learn↑, *memory↑, *GAD1/GAD67↑, *RELN↑, *p‑NMDAR↑, *neuroP↑,
8069- KAE,    Kaempferol attenuates cognitive deficit via regulating oxidative stress and neuroinflammation in an ovariectomized rat model of sporadic dementia
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *Learn↑, *memory↑, *SOD↑, *GSH↑, *TNF-α↓, *MDA↓,
7827- KAE,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*neuroP↑, *Learn↑, *memory↑, *antiOx↑, *Inflam↓, *Aβ↓, *cognitive↑, *BDNF↑, *TrkB↑, *CREB↑, *ERβ/ESR2↑, *ERK↑, *ROS↓, *AChE↓, *Dose↑,
8145- LF,    Neuroprotective Effects of Lactoferrin in Alzheimer's and Parkinson's Diseases: A Narrative Review
- Review, AD, NA - Review, Park, NA
*AntiBio↑, *Imm↑, *AntiCan↑, *neuroP↑, *BBB↑, *APOE4↓, *ROS↓, *Inflam↓, *Apoptosis↓, *Learn↑, *memory↑, *ADAM10↑, *PSEN1/PS1↑, *cl‑APP↑, *BACE/β-secretase↓, *cognitive↑, *MDA↓, *IL6↓, *TNF-α↓, *neuroP↑, *Dose↝, *IronCh↑, *SOD↑, *BioAv↝,
8329- LIN,    Microglial-targeting induced by intranasal linalool during neurological protection postischemia
- in-vivo, Stroke, NA - in-vivo, AD, NA
*Stroke↓, *BioAv↑, *neuroP↑, *motorD↑, *Learn↑, *COX2/PTGS2↓, *IL1β↓, *NRF2↑, *Dose↝, *cognitive↑,
8382- LT,    Luteolin as a dietary flavonoid for brain health: modulating neuroinflammation and cognitive decline in neurodegenerative disorders
- Review, AD, NA - Review, Park, NA
*neuroP↑, *Inflam↓, *antiOx↑, *NF-kB↓, *NRF2↑, *BDNF↑, *cognitive↑, *motorD↑, *BBB↑, *BioAv↓, *NO↓, *ROS↓, *NRF2↑, *ARE↑, *MMP↑, *BDNF↑, *Learn↑, *memory↑, *cognitive↑, *p‑JNK↓, *GFAP↓, *AIF1/Iba-1↓, *TNF-α↓, *IL1β↓, *BAX↓, *COX2/PTGS2↓, *BACE/β-secretase↓, *Aβ42↓, *PSD95↑, *SNAP25↑, *lipid-P↓, *GSTs↓, *GSH↑, *SOD↓, *Catalase↓, *AChE↓, *Casp3↓, *Casp9↓,
8379- LT,    Luteolin and neuroinflammation: a multi-target therapeutic strategy for central nervous system disorders
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*neuroP↑, *Inflam↓, *ROS↓, *Apoptosis↓, *BioAv↓, *BBB∅, Ferroptosis↑, ROS↑, Iron↑, lipid-P↑, MDA↑, GSH↓, GPx4↓, *Aβ↓, *memory↑, *neuroG↑, *NRF2↑, *NLRP3↓, *ROS↓, JAK2↓, STAT3↓, PD-L1↓, Perforin↝, GranB/GZMB↝, hepatoP↑, *Learn↑, *TNF-α↓, *IL1β↓, *IL6↓, *NO↓, *COX2/PTGS2↓, *iNOS↓, *ER Stress↓, *GRP78/BiP↓, *IRE1↓, *cognitive↑, *BAX↓, *Bcl-2↓, *Casp3↓, *PSD95↑, *SNAP25↑, *JNK↓, *eff↑, *mtDam↓, *MMP↑, *Stroke↓, *TJ↑, *MMP9↓, *BBB∅, *NeuroI↓,
8351- Lut,  Zeax,    Lutein and Zeaxanthin Influence Brain Function in Older Adults: A Randomized Controlled Trial
- Trial, AD, NA
*Dose↝, *cognitive↑, *Learn↑, *neuroP↑,
8421- Lyco,    Lycopene: Sojourn from kitchen to an effective therapy in Alzheimer's disease
- Review, AD, NA
*neuroP↑, *antiOx↑, *Inflam↓, *AntiMyl↑, *ROS↓, *MMP↑, *NGF↑, *BDNF↑, *VEGF↑, *Aβ42↓, *PI3K↑, *Akt↑, *NRF2↑, *lipid-P↓, *GSH↑, *Catalase↑, *SOD↑, *cognitive↑, *Learn↑, *memory↑, *APP↓, *BACE/β-secretase↓, *ADAM10↑, *NF-kB↓, *AChE↓, *MAOA↓, *BioAv↝,
8455- Mg,    Magnesium-L-threonate treats Alzheimer's disease by modulating the microbiota-gut-brain axis
- in-vivo, AD, NA
*Learn↑, *memory↑, *cognitive↑, *ROS↓, *Inflam↓, *GutMicro↑, *IBI↑, *MDA↓, *SOD↑, *Catalase↑, *TNF-α↓, *IL1β↓, *IL10↑,
8471- Mg,    Magnesium protects cognitive functions and synaptic plasticity in streptozotocin-induced sporadic Alzheimer's model
- in-vivo, AD, NA
*Learn?, *memory?, *p‑tau↓, *GSK‐3β↑, *Akt↑, *PI3K↑, *cognitive↑,
8451- Oreg,    A multi-parameter evaluation of the neuroprotective and cognitive-enhancing effects of Origanum onites L. (Turkish Oregano) essential oil on scopolamine-induced amnestic rats
- in-vivo, AD, NA
*Learn↑, *memory↑, *AChE↓, *ROS↓, *COX2/PTGS2↓, *iNOS↓,
7834- VA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*neuroP↑, *memory↑, *Learn↑, *Aβ↓, *BACE/β-secretase↓, *NeuroI↓, *RAGE↓, *antiOx↑, *NRF2↑, *HO-1↑, *GSK‐3β↓, *ROS↓, *AChE↓, *Dose↝,
7902- VT,    Vitexin Protects Against Scopolamine-Induced Cognitive Impairment by Preserving Synaptic Integrity and Modulating Nrf2/HO-1 and NF-κB Signaling Pathways
- in-vivo, AD, NA
*Dose↝, *Learn↑, *memory↑, *AChE↓, *lipid-P↓, *TOS↓, *MDA↓, *ONOO↓, *NO↓, *NOS2↓, *TAC↑, *BDNF↑, *GDNF↑, *PSD95↑, *GFAP↓, *NF-kB↓, *COX2/PTGS2↓, *NRF2↑, *HO-1↑, *neuroP↑, *NeuroI↓,

Showing Research Papers: 1 to 24 of 24

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 24

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

GFAP↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

Ferroptosis↑, 1,   GPx4↓, 1,   GSH↓, 1,   Iron↑, 1,   lipid-P↑, 1,   MDA↑, 1,   ROS↑, 1,  

Cell Death(tgid=5) ⓘ

Ferroptosis↑, 1,   GranB/GZMB↝, 1,   Perforin↝, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

STAT3↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

JAK2↓, 1,   PD-L1↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

PD-L1↓, 1,  

Functional Outcomes(tgid=23) ⓘ

hepatoP↑, 1,  
Total Targets: 16

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AIF1/Iba-1↓, 1,   AntiBio↑, 1,   APOE4↓, 1,   Aβ42↓, 2,   GAD1/GAD67↑, 1,   GDNF↑, 1,   GFAP↓, 2,   Learn?, 1,   Learn↑, 23,   NeuroI↓, 3,   p‑NMDAR↑, 1,   ONOO↓, 1,   PSEN1/PS1↑, 1,   RELN↑, 1,   SNAP25↑, 2,   Stroke↓, 2,   SYP↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 6,   ARE↑, 1,   Catalase↓, 1,   Catalase↑, 2,   Copper↓, 1,   GPx↑, 1,   GSH↑, 4,   GSTs↓, 1,   HO-1↑, 5,   lipid-P↓, 5,   MDA↓, 4,   NQO1↑, 1,   NRF2↓, 1,   NRF2↑, 10,   ROS↓, 14,   SOD↓, 1,   SOD↑, 5,   SOD1↑, 1,   TAC↑, 2,   TOS↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↑, 3,   mtDam↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

CREB↑, 1,   LDH↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 2,   Apoptosis↓, 3,   BAX↓, 2,   Bax:Bcl2↓, 1,   Bcl-2↓, 1,   Bcl-2↑, 1,   Casp3↓, 2,   Casp9↓, 1,   iNOS↓, 2,   JNK↓, 1,   p‑JNK↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 1,   GRP78/BiP↓, 1,   IRE1↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 1,   GSK‐3β↓, 2,   GSK‐3β↑, 1,   p‑GSK‐3β↓, 1,   p‑GSK‐3β↑, 1,   neuroG↑, 1,   PI3K↑, 2,  

Migration(tgid=13) ⓘ

APP↓, 1,   cl‑APP↑, 1,   MMP9↓, 1,   RAGE↓, 1,   TJ↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 4,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   BBB∅, 2,   IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 5,   IL10↑, 1,   IL1β↓, 5,   IL6↓, 3,   Imm↑, 1,   Inflam↓, 11,   MIP‑1α/CCL3↓, 1,   NF-kB↓, 3,   TNF-α↓, 6,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 6,   ADAM10↑, 2,   BDNF↑, 6,   MAOA↓, 1,   NGF↑, 1,   PSD95↑, 4,   p‑tau↓, 2,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 8,   BACE/β-secretase↓, 6,   NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ERβ/ESR2↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 1,   BioAv↝, 2,   Dose↑, 1,   Dose↝, 5,   eff↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

GutMicro↑, 1,   IL6↓, 3,   LDH↓, 1,   NOS2↓, 1,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiMyl↑, 1,   cognitive↑, 16,   memory?, 1,   memory↓, 1,   memory↑, 18,   motorD↑, 3,   neuroP↑, 16,   radioP↑, 1,  
Total Targets: 114

Scientific Paper Hit Count for: Learn, Learning
3 Kaempferol
2 Hyperoside
2 Isoliquiritigenin
2 isoquercitrin
2 Mung Bean Sprouts
2 Luteolin
2 Magnesium
1 Caffeic acid
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Date Fruit Extract
1 HydroxyTyrosol
1 Radiotherapy/Radiation
1 Lactoferrin/Talactoferrin
1 Linalool
1 Lutein
1 Zeaxanthin
1 Lycopene
1 Oregano
1 Vanillic Acid
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1656  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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