NeuroI Cancer Research Results

NeuroI, NeuroInflammation: Click to Expand ⟱
Source:
Type:

NeuroInflammation
Scientific Papers found: Click to Expand⟱
7815- Api,  LT,  NarG,  QC,  MOR  The role of natural flavonoids on neuroinflammation as a therapeutic target for Alzheimer’s disease: a narrative review
- Review, AD, NA
*NeuroI↓,
7832- CA,  CGA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*BBB↑, *cognitive↑, *memory↑, *ROS↓, *p‑tau↓, *GSK‐3β↓, *MAPK↓, *NeuroI↓, *P53↓, *Casp3↓, *AChE↓, *APP↓, *BACE/β-secretase↓, *neuroP↑, *Dose↝,
7833- GA,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*neuroP↑, *Dose↝, *ADAM10↝, *BACE/β-secretase↓, *cl‑APP↓, *Aβ↓, *Ca+2↓, *ROS↓, *NeuroI↓,
7862- isoO,    Isoorientin attenuates lipopolysaccharide-induced pro-inflammatory responses through down-regulation of ROS-related MAPK/NF-κB signaling pathway in BV-2 microglia
- in-vitro, Nor, BV2
*Apoptosis↓, *iNOS↓, *COX2/PTGS2↓, *NO↓, *TNF-α↓, *MAPK↓, *NF-kB↓, *ROS↓, *NeuroI↓,
7864- isoO,    Isoorientin Inhibits Amyloid β25-35-Induced Neuronal Inflammation in BV2 Cells by Blocking the NF-κB Signaling Pathway
- in-vitro, AD, BV2
*iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL6↓, *ROS↓, *NF-kB↓, *Apoptosis↓, *Bcl-2↑, *BAX↓, *cl‑Casp9↓, *cl‑Casp3↓, *cl‑PARP↓, *NeuroI↓,
7851- isoO,    Isoorientin, a GSK-3β inhibitor, rescues synaptic dysfunction, spatial memory deficits and attenuates pathological progression in APP/PS1 model mice
- in-vivo, AD, NA
*GSK‐3β↓, *neuroP↑, *p‑tau↓, *Aβ↓, *NeuroI↓, *cognitive↑, *neuroP↑,
9232- ITCs,  SFN,    The role of isothiocyanate-rich plants and supplements in neuropsychiatric disorders: a review and update
- Review, AD, NA
*ROS↓, *Inflam↓, *eff↑, *toxicity↓, *HDAC?, *neuroP↑, *NRF2↑, *cognitive↑, *tau↓, *HSP70/HSPA5↑, *CHIP↑, *memory↑, *NeuroI↓, *ROS↓, *BACE/β-secretase↓, *BDNF↑, *GSH↑, *GPx↑, *AChE↓, *BChE↓, *TC↓, *TG/TAG↓, *LDL↓, ROS↑,
7912- IVT,    Isovitexin modulates autophagy in Alzheimer’s disease via miR-107 signalling
- in-vivo, AD, NA
*memory↑, *Aβ↓, *NeuroI↓, *PI3K↓, *Akt↓, *mTOR↓, *miR-107↑,
8379- LT,    Luteolin and neuroinflammation: a multi-target therapeutic strategy for central nervous system disorders
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*neuroP↑, *Inflam↓, *ROS↓, *Apoptosis↓, *BioAv↓, *BBB∅, Ferroptosis↑, ROS↑, Iron↑, lipid-P↑, MDA↑, GSH↓, GPx4↓, *Aβ↓, *memory↑, *neuroG↑, *NRF2↑, *NLRP3↓, *ROS↓, JAK2↓, STAT3↓, PD-L1↓, Perforin↝, GranB/GZMB↝, hepatoP↑, *Learn↑, *TNF-α↓, *IL1β↓, *IL6↓, *NO↓, *COX2/PTGS2↓, *iNOS↓, *ER Stress↓, *GRP78/BiP↓, *IRE1↓, *cognitive↑, *BAX↓, *Bcl-2↓, *Casp3↓, *PSD95↑, *SNAP25↑, *JNK↓, *eff↑, *mtDam↓, *MMP↑, *Stroke↓, *TJ↑, *MMP9↓, *BBB∅, *NeuroI↓,
8387- LT,  QC,  Api,  Ba,    Identification of Flavonoid Compounds in Treating Alzheimer's Disease Based on Network Medicine Framework Strategy
- in-vitro, AD, NA
*neuroP↑, *MMP↑, *Apoptosis↓, *Akt↓, *NF-kB↓, *pol-M2 MC↑, *NeuroI↓,
8414- Lyco,    Exploring the Therapeutic Potential of Lycopene: Mechanisms, Biological Activities, and Health Benefits
- Review, Var, NA - Review, AD, NA
*ROS↓, *Inflam↓, *hepatoP↑, *cardioP↑, *neuroP↑, *AntiArt↑, *Obesity↓, *Wound Healing↑, *BioAv↑, *GSTs↑, *Trx1↑, *SOD↑, *Catalase↑, *ALAT↓, *LDH↓, *AST↓, *MDA↓, *cognitive↑, *memory↑, *NeuroI↓, *Aβ↓, *LRP1↑, *RAGE↓, *NRF2↑, *HO-1↑, tumCV?, Bax:Bcl2↑, DNAdam↑, Apoptosis↑, β-catenin/ZEB1↓, cMyc↓, cycD1/CCND1↓, ROS↓, TumCCA↑, Akt↓, *Synergy↑, *MDA↓, *NF-kB↓, *TGF-β↓, *Casp3↓, *Catalase↑, *GSH↑, *Bcl-2↑, *IL10↑, *MUC1↑, *IBI↑, *RenoP↑, *ChemoSen↑, *Synergy↑, *Synergy↑, *BMD↑,
8734- M-Blu,    From Mitochondrial Function to Neuroprotection – An Emerging Role for Methylene Blue
- Review, AD, NA
*ETC↑, *compIV↑, *ROS↓, *NeuroI↓, *neuroP↑, *Stroke↓, *cognitive↑, *BBB↑, *BloodF↑, *NOS2↓, *lipid-P↓, *Inflam↓, *Synergy↑, *OCR↑, *compIV↑, *ATP↑, *Casp↓, *MMP↑, *tau↓,
8494- MAG,    Magnolol Ameliorates Behavioral Impairments and Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease
- in-vivo, AD, NA
*cognitive↑, *PSD95?, *SYN1↑, *SYT1↑, *IL10↑, *TNF-α↓, *IL6↓, *Aβ42↓, *GFAP↓, *other↑, *cognitive↑, *NeuroI↓, *Aβ↓, *GSK‐3β↓, *NF-kB↓,
8507- MAG,    Magnolol acts as a neurorestorative agent in an Aβ1‑42‑induced mouse model of Alzheimer's disease
- in-vivo, AD, NA
*Dose?, *cognitive↑, *Aβ↓, *NeuroI↓, *neuroP↑, *tau↓, *GFAP↓, *AIF1/Iba-1↓, *GSK‐3β↑, *SYP↑, *BDNF↑,
8931- MBS,  VT,  IVT,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer’s Disease
- Review, AD, NA
*Ingr↝, *neuroP↑, *p‑tau↓, *ROS↓, *NeuroI↓, *AChE↓,
8689- MLT,    Role of melatonin in Alzheimer's disease: From preclinical studies to novel melatonin-based therapies
- Review, AD, NA
*neuroP↑, *Aβ↓, *ROS↓, *NeuroI↓, *Apoptosis↓, *mtDam↓, *GSK‐3β↓, *p‑tau↓, *GFAP↓, *TNF-α↓, *IL6↓, *BACE/β-secretase↓, *PSEN1/PS1↓, *NF-kB↓, *TFAM↑, *Nrf1↑, *NRF2↑, *PGC-1α↑, *MMP↑, *GSH↑, *lipid-P↓, *ChAT↑, *TBARS↓, *SOD↑, *Ca+2↓, *AChE↓, *H2O2↓, *MDA↓, *TAC↑, *SOD↑, *Catalase↑, *BDNF↑, *Bcl-2↑, *Ach↑, *memory↑, *Learn↑, *GSK‐3β↓, *SNAP25↑, *PSD95↑, *p‑CREB↑, *GFAP↓, *RELN↑, *SIRT1↑, *TFAM↑, *APP↓, *ER Stress↓, *GRP78/BiP↓, *Sleep↑, *cognitive↑, *Synergy↑, *NeuroI↓,
8872- MOR,    Morin attenuates memory deficits in a rat model of Alzheimer's disease by ameliorating oxidative stress and neuroinflammation
- in-vivo, AD, NA
*Dose↝, *MDA↓, *NO↓, *GSH↑, *Catalase↑, *TNF-α↓, *IL1β↓, *IL6↓, *NF-kB↓, *BDNF↑, *antiOx↑, *NeuroI↓, *memory↑,
8964- mushLions,    Lion’s Mane Mushroom (Hericium erinaceus): A Neuroprotective Fungus with Antioxidant, Anti-Inflammatory, and Antimicrobial Potential—A Narrative Review
- Review, Nor, NA - Review, AD, NA
*Ingr↝, *ROS↓, *antiOx↑, *AntiBio↑, *NGF↑, *neuroG↑, *memory↑, *neuroP↑, *NF-kB↓, *COX2/PTGS2↓, *NeuroI↓, *cognitive↑, *NRF2↑, *SOD↑, *GPx↑, *GutMicro↑, *BBB↑, *BioAv↝,
7831- PCA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*BBB↑, *neuroP↑, *Aβ↓, *p‑tau↓, *autophagy↓, *GSK‐3β↓, *NeuroI↓, *iNOS↓, *COX2/PTGS2↓, *BDNF↑, *MEF2D↑, *cognitive↑, *memory↑,
7830- SA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*cognitive↑, *memory↑, *antiOx↑, *NeuroI↓, *iNOS↓, *3-NT↓, *Ach↑, *ChAT↑, *Dose↝, *neuroP↑,
9033- SP,    Spirulina and Its Bioactive Compounds as Multi-Target Anticancer Agents: Mechanisms, Immune Modulation, and Translational Potential
- Review, Var, NA
Apoptosis↑, TumCCA↑, angioG↓, VEGF↓, VEGFR1↓, EMT↓, Ingr↝, Imm↑, pol-M1↑, Th1 response↑, Th17↑, chemoP↑, BioAv↓, Synergy?, Ingr↝, Ingr↝, Ingr↝, ROS⇅, ROS↑, mtDam↑, DNAdam↑, SOD↓, Bcl-2↓, Casp3↑, MDA↓, Catalase↑, ROS↓, MOMP↑, Cyt‑c↑, Casp9↑, CellShr↑, ChrCon↑, Dose↝, TNFR 1↑, FADD↑, TRADD↑, Beclin-1/ATG6↑, PI3K↓, Akt↓, mTOR↓, TumAuto↑, TumCMig↓, TumCI↓, Vim↓, Fibronectin↓, COL1↓, MMP2↓, MMP9↓, COX2/PTGS2↓, MCP1/CCL2↓, ICAM-1↓, VCAM-1↓, Snail↓, Slug↓, Zeb1↓, Twist↓, E-cadherin↑, chemoP↑, *hepatoP↑, *lipid-P↓, *Casp3↓, *BAX↓, RenoP↑, *creat↓, *Urea↓, *SOD↑, *Catalase↑, *neuroP↑, *cognitive↑, *ROS↓, *NeuroI↓, *memory↑, *BDNF↑, *CREB↑, *toxicity↓, *toxicity↝, *BioAv↓, *BioAv↓, *Half-Life↝,
7834- VA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*neuroP↑, *memory↑, *Learn↑, *Aβ↓, *BACE/β-secretase↓, *NeuroI↓, *RAGE↓, *antiOx↑, *NRF2↑, *HO-1↑, *GSK‐3β↓, *ROS↓, *AChE↓, *Dose↝,
7902- VT,    Vitexin Protects Against Scopolamine-Induced Cognitive Impairment by Preserving Synaptic Integrity and Modulating Nrf2/HO-1 and NF-κB Signaling Pathways
- in-vivo, AD, NA
*Dose↝, *Learn↑, *memory↑, *AChE↓, *lipid-P↓, *TOS↓, *MDA↓, *ONOO↓, *NO↓, *NOS2↓, *TAC↑, *BDNF↑, *GDNF↑, *PSD95↑, *GFAP↓, *NF-kB↓, *COX2/PTGS2↓, *NRF2↑, *HO-1↑, *neuroP↑, *NeuroI↓,

Showing Research Papers: 1 to 23 of 23

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 23

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

Catalase↑, 1,   GPx4↓, 1,   GSH↓, 1,   Iron↑, 1,   lipid-P↑, 1,   MDA↓, 1,   MDA↑, 1,   ROS↓, 2,   ROS↑, 3,   ROS⇅, 1,   SOD↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

mtDam↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 2,   Bax:Bcl2↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,   Casp9↑, 1,   CellShr↑, 1,   Cyt‑c↑, 1,   FADD↑, 1,   Ferroptosis↑, 1,   GranB/GZMB↝, 1,   MOMP↑, 1,   Perforin↝, 1,   TNFR 1↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   JAK2↓, 1,   mTOR↓, 1,   PI3K↓, 1,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cMyc↓, 1,   tumCV?, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

ChrCon↑, 1,   cycD1/CCND1↓, 1,   TumCCA↑, 2,  

Migration(tgid=13) ⓘ

COL1↓, 1,   E-cadherin↑, 1,   EMT↓, 1,   Fibronectin↓, 1,   MMP2↓, 1,   MMP9↓, 1,   Slug↓, 1,   Snail↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   Twist↓, 1,   Vim↓, 1,   Zeb1↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   VCAM-1↓, 1,   VEGF↓, 1,   VEGFR1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   ICAM-1↓, 1,   Imm↑, 1,   pol-M1↑, 1,   MCP1/CCL2↓, 1,   PD-L1↓, 1,   Th1 response↑, 1,   Th17↑, 1,   TRADD↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   Dose↝, 1,   Synergy?, 1,  

Clinical Biomarkers(tgid=22) ⓘ

PD-L1↓, 1,  

Functional Outcomes(tgid=23) ⓘ

chemoP↑, 2,   hepatoP↑, 1,   RenoP↑, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 4,  
Total Targets: 73

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

3-NT↓, 1,   antiOx↑, 4,   Catalase↑, 5,   GPx↑, 2,   GSH↑, 4,   GSTs↑, 1,   H2O2↓, 1,   HO-1↑, 3,   lipid-P↓, 4,   MDA↓, 5,   Nrf1↑, 1,   NRF2↑, 7,   ONOO↓, 1,   ROS↓, 15,   SOD↑, 5,   TAC↑, 2,   TBARS↓, 1,   TOS↓, 1,   Trx1↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compIV↑, 2,   ETC↑, 1,   mtDam↓, 2,   OCR↑, 1,   PGC-1α↑, 1,   TFAM↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   ATP↑, 1,   GSK‐3β↓, 7,   GSK‐3β↑, 1,   LDL↓, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 5,   BAX↓, 3,   Bcl-2↓, 1,   Bcl-2↑, 3,   Casp↓, 1,   Casp3↓, 4,   cl‑Casp3↓, 1,   cl‑Casp9↓, 1,   iNOS↓, 5,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   CREB↑, 1,   p‑CREB↑, 1,   JNK↓, 1,   MAPK↓, 2,   mTOR↓, 1,   PI3K↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

HDAC?, 1,   MEF2D↑, 1,   miR-107↑, 1,   other↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 2,   GRP78/BiP↓, 2,   HSP70/HSPA5↑, 1,   IRE1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

autophagy↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↓, 1,   cl‑PARP↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CHIP↑, 1,   neuroG↑, 2,  

Migration(tgid=13) ⓘ

Ca+2↓, 2,   LRP1↑, 1,   MMP9↓, 1,   MUC1↑, 1,   TGF-β↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 4,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 4,   BBB∅, 2,   IBI↑, 1,   MMP↑, 4,   TJ↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 1,   COX2/PTGS2↓, 6,   IL10↑, 2,   IL1β↓, 2,   IL6↓, 5,   Inflam↓, 4,   pol-M2 MC↑, 1,   NeuroI↓, 24,   NF-kB↓, 9,   NLRP3↓, 1,   RAGE↓, 2,   TNF-α↓, 6,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 5,  

Synaptic & Neurotransmission(tgid=18) ⓘ

Ach↑, 2,   AChE↓, 6,   ADAM10↝, 1,   BChE↓, 1,   BDNF↑, 7,   ChAT↑, 2,   GDNF↑, 1,   NGF↑, 1,   PSD95?, 1,   PSD95↑, 3,   RELN↑, 1,   SNAP25↑, 2,   SYN1↑, 1,   SYP↑, 1,   SYT1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 2,   cl‑APP↓, 1,   Aβ↓, 10,   Aβ42↓, 1,   BACE/β-secretase↓, 5,   PSEN1/PS1↓, 1,   tau↓, 3,   p‑tau↓, 5,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 1,   BioAv↝, 1,   ChemoSen↑, 1,   Dose?, 1,   Dose↝, 6,   eff↑, 2,   Half-Life↝, 1,   Synergy↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   BloodF↑, 1,   BMD↑, 1,   creat↓, 1,   IL6↓, 5,   LDH↓, 1,   NOS2↓, 2,   RAGE↓, 2,   TC↓, 1,   TG/TAG↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiArt↑, 1,   cardioP↑, 1,   cognitive↑, 14,   hepatoP↑, 2,   Learn↑, 4,   memory↑, 13,   neuroP↑, 18,   Obesity↓, 1,   RenoP↑, 1,   Sleep↑, 1,   Stroke↓, 2,   toxicity↓, 2,   toxicity↝, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 1,   GutMicro↑, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 2,  
Total Targets: 145

Scientific Paper Hit Count for: NeuroI, NeuroInflammation
5 Mung Bean Sprouts
3 Luteolin
3 isoorientin
2 Apigenin (mainly Parsley)
2 Quercetin
2 Morin
2 Isovitexin
2 Magnolol
2 Vitexin
1 Naringin
1 Caffeic acid
1 Chlorogenic acid
1 Gallic acid
1 Isothiocyanates
1 Sulforaphane (mainly Broccoli)
1 Baicalein
1 Lycopene
1 Methylene blue
1 Melatonin
1 Mushroom Lion’s Mane, Hericium erinaceus
1 Protocatechuic acid
1 Sinapic acid
1 Spirulina(Arthrospira/Limnospira)
1 Vanillic Acid
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1707  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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