Airway Cancer Research Results

Airway, Airway Resistance/Airway Resistance: Click to Expand ⟱
Source:
Type:

Airway Resistance

Aliases: Lung Resistance; Pulmonary Resistance; Raw; RL

Definition: Airway resistance is the opposition to airflow through the respiratory tract. It increases when airway diameter decreases because of bronchoconstriction, airway-wall swelling, mucus accumulation, or structural remodeling. Lung resistance or pulmonary resistance (RL) is commonly reported in animal asthma studies and may include resistance arising from both the conducting airways and other components of the respiratory system.

Asthma relevance: Airway/lung resistance is commonly increased in asthma and is frequently measured after challenge with methacholine or another bronchoconstrictor. A reduction in elevated or methacholine-induced resistance generally indicates improved airway function.

Direction:
Airway Resistance ↑ = generally adverse
Airway Resistance ↓ = generally beneficial in asthma

Typical pathway:
Bronchoconstriction / mucus / airway inflammation → airway lumen narrowing → Airway Resistance ↑



Scientific Papers found: Click to Expand⟱
7933- H2,    Hydrogen inhalation ameliorates lung inflammation in mice with asthma
- in-vivo, Asthma, NA
*antiOx↑, *Inflam↓, *IL4↓, *IL5↓, *IL13↓, *IL10↑, *TGF-β1↑, *IgE↓, *MDA↓, *SOD↑, *Airway↓,
7926- H2,    Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model
- in-vivo, Asthma, NA
*Dose↝, *Airway↓, *BALF-Infl↓, *Th2↓, *IL4↓, *IgE↓, *MDA↓, *SOD↑, *NF-kB↓, *NRF2↑,
7925- H2,    Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice
- in-vivo, Asthma, NA
*Dose?, *IL4↓, *IL13↓, *TNF-α↓, *CXCL15↓, *SOD↑, *MDA↓, *MPO↓, *ROS↓, *antiOx↑, *Inflam↓, *Apoptosis↓, *toxicity↓, *Stroke↓, *Airway↓, *Neut↓, *Eos↓, *BALF-Lym↓, *BALF-Infl↓, *AirwayM↓,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

Airway↓, 3,   AirwayM↓, 1,   BALF-Infl↓, 2,   BALF-Lym↓, 1,   CXCL15↓, 1,   Eos↓, 1,   IgE↓, 2,   IL13↓, 2,   Stroke↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   MDA↓, 3,   MPO↓, 1,   NRF2↑, 1,   ROS↓, 1,   SOD↑, 3,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,  

Migration(tgid=13) ⓘ

TGF-β1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL10↑, 1,   IL4↓, 3,   IL5↓, 1,   Inflam↓, 2,   Neut↓, 1,   NF-kB↓, 1,   Th2↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose?, 1,   Dose↝, 1,  

Functional Outcomes(tgid=23) ⓘ

toxicity↓, 1,  
Total Targets: 28

Scientific Paper Hit Count for: Airway, Airway Resistance/Airway Resistance
3 Hydrogen Gas
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1725  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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