antiAll Cancer Research Results

antiAll, antiallergic/antiasmatic: Click to Expand ⟱
Source:
Type:

Antiallergic Activity - Suppression of Allergic Responses

Type: Therapeutic effect / immune phenotype / functional outcome

Function: Antiallergic activity refers to suppression of allergic sensitization, mast-cell or basophil activation, IgE-mediated signaling, eosinophilic inflammation, histamine and leukotriene release, airway inflammation, or other manifestations of hypersensitivity.

Asthma: ↓ Allergic response is favorable. Increased antiallergic activity corresponds to reduced IgE/FcεRI signaling, mast-cell degranulation, eosinophil recruitment, type-2 cytokine signaling, mucus production, bronchoconstriction, and airway hyperresponsiveness.

Favorable Direction: ↑ Antiallergic activity = beneficial.
Scientific Papers found: Click to Expand⟱
6461- 1,8-Cin,    1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases
- Review, AD, NA - Review, Var, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *Half-Life↝, *toxicity↓, *PGE2↓, *TNF-α↓, *IL1β↓, *NO↓, *NF-kB↓, *PPARγ↓, COX2/PTGS2↓, *ROS↓, *SOD↑, *Catalase↑, *TAC↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *NADPH↑, *GPx↑, *AntiBio↑, *Synergy↑, *AntiFungal↑, *AntiViral↑, *TRPA1↑, Synergy↑, TumCCA↑, ROS↑, MAPK↝, mTOR↝, Apoptosis↑, survivin↓, Akt↓, p38↑, cl‑PARP↑, cl‑Casp3⇅, P53↑, BAX↑, Cyt‑c↑, Casp9↑, Dose↝, *Aβ↓, *tau↓, *GSK‐3β↓, *BACE/β-secretase↓, *cardioP↑, MFN2↑, *antiAll↑,
6468- 1,8-Cin,    Inhibitory activity of 1,8-cineol (eucalyptol) on cytokine production in cultured human lymphocytes and monocytes
- in-vitro, Nor, NA
*TNF-α↓, *IL1β↓, *antiAll↑,
6763- AL,    Revealing the Therapeutic Uses of Garlic (Allium sativum) and Its Potential for Drug Discovery
- Review, Nor, NA
*Inflam↓, *AntiBio↑, *AntiDiabetic↑, *hepatoP↑, *antiOx↑, *AntiFungal↑, *Wound Healing↑, *other↑, *BP↓, *LDL↓, *AntiAg↑, *cognitive↑, *memory↑, Risk↑, *COX1↓, *TXA2↓, *antiAll↑,
6594- Anamu,    Dibenzyl trisulfide induces caspase-independent death and lysosomal membrane permeabilization of triple-negative breast cancer cells
- in-vitro, BC, HCC1806/CRL-2335 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
TumCP↓, TumCMig↓, Bak↑, GADD45A↑, LTA/TNF-β↑, lysoMP↑, P450↓, cl‑PARP↑, Dose↝, *antiAll↑,
3385- ART/DHA,    Interaction of artemisinin protects the activity of antioxidant enzyme catalase: A biophysical study
- Study, Nor, NA
*NF-kB↑, *Catalase↑, *antiAll↑,
4815- ASTX,    The Promising Effects of Astaxanthin on Lung Diseases
- Review, Var, NA
Dose↑, *BioAv↝, *BioAv↝, *antiOx↑, *NRF2↑, *ERK↓, *antiAll↑,
2614- Ba,    Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders
- Review, Nor, NA
*toxicity↓, *antiOx↑, *Inflam↓, *ROS↓, *NF-kB↓, *MCP1/CCL2↓, *hepatoP↑, *neuroP↑, *antiAll↑,
9175- BITC,  PEITC,  AITC,    Isothiocyanates in medicine: A comprehensive review on phenylethyl-, allyl-, and benzyl-isothiocyanates
- Review, Nor, NA
*Inflam↓, *antiOx↑, *AntiBio↑, *BioAv↝, *BioAv↑, *TNF-α↓, *IL10↓, *antiAll↑, *NRF2↑, *SOD↑, *GPx↑, *HO-1↑, *NQO1↑, *GSH↑, *GSTs↑, *hepatoP↑, *MDA↓, *Catalase↑, *ROS↓, *ROS⇅, *ROS↑, *IP-10/CXCL-10↓, *CD40↓, STAT1↓, iNOS↓, STAT3↓, IL6↓, *MPO↓, Casp3↑, Casp8↑, Casp9↑, mtDam↑, compIV↓, Cyt‑c↑, SDH↓, AIF↑, p‑Akt↓, PTEN↑, MMP2↓, MMP9↓, TumCCA↑, CDK1↓, CDC25↓, *eff↑, *toxicity↝, *eff↑, *eff↑, EMT↓, *AntiAg↑,
1185- Bos,    The journey of boswellic acids from synthesis to pharmacological activities
- Review, Var, NA
BAX↑, NF-kB↓, cl‑PARP↑, Casp3↑, Casp8↑, *antiAll↑, *STAT6↓,
2776- Bos,    Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities
- Review, Var, NA
*5LO↓, *TNF-α↓, *MMP3↓, *COX1↓, *COX2/PTGS2↓, *PGE2↓, *Th2↑, *Catalase↑, *SOD↑, *NO↑, *PGE2↑, *IL1β↓, *IL6↓, *Th1 response↓, *Th2↑, *iNOS↓, *NO↓, *p‑JNK↓, *p38↓, GutMicro↑, p‑Akt↓, GSK‐3β↓, cycD1/CCND1↓, Akt↓, STAT3↓, CSCs↓, AR↓, P21↑, DR5↑, CHOP/DDIT3↑, Casp3↑, Casp8↑, cl‑PARP↑, DNAdam↑, p‑RB1↓, FOXM1↓, TOP2↓, CDC25↓, p‑CDK1↓, p‑ERK↓, MMP9↓, VEGF↓, angioG↓, ROS↑, Cyt‑c↑, AIF↑, Diablo↑, survivin↓, ICAD↓, ChemoSen↑, SOX9↓, ER Stress↑, GRP78/BiP↑, cal2↓, AMPK↓, mTOR↓, ROS↓, *antiAll↑,
2775- Bos,    The journey of boswellic acids from synthesis to pharmacological activities
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
ROS↑, ER Stress↑, TumCG↓, Apoptosis↑, Inflam↓, ChemoSen↑, Casp↑, ERK↓, cl‑PARP↑, AR↓, cycD1/CCND1↓, VEGFR2/KDR/Flk1↓, CXCR4↓, radioP↑, NF-kB↓, VEGF↓, P21↑, Wnt↓, β-catenin/ZEB1↓, Cyt‑c↑, MMP2↓, MMP1↓, MMP9↓, PI3K↓, MAPK↓, JNK↑, *5LO↓, *NRF2↑, *HO-1↑, *MDA↓, *SOD↑, *hepatoP↑, *ALAT↓, *AST↓, *LDH↑, *CRP↓, *COX2/PTGS2↓, *GSH↑, *ROS↓, *Imm↑, *Dose↝, *eff↑, *neuroP↑, *cognitive↑, *IL6↓, *TNF-α↓, *AntiArt↑, *AntiDiabetic↑, *antiAll↑,
2767- Bos,    The potential role of boswellic acids in cancer prevention and treatment
- Review, Var, NA
*Inflam↓, AntiCan↑, *MAPK↑, *Ca+2↝, p‑ERK↓, TumCI↓, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, p‑RB1↓, *NF-kB↓, *TNF-α↓, NF-kB↓, IKKα↓, MCP1/CCL2↓, IL1α↓, MIP2↓, VEGF↓, Tf↓, COX2/PTGS2↓, MMP9↓, CXCR4↓, VEGF↓, Synergy↑, PPARα↓, lipid-P?, STAT3↓, TOP1↓, TOP2↑, 5HT↓, p‑PDGFR-BB↓, PDGF↓, AR↓, DR5↑, angioG↓, DR4↑, Casp3↑, Casp8↑, cl‑PARP↑, eff↑, chemoPv↑, Wnt↓, β-catenin/ZEB1↓, ascitic↓, Let-7↑, miR-200b↑, Synergy↑, MMP1↓, MMP2↓, Synergy↑, BioAv↓, BioAv↑, Half-Life↓, toxicity↓, Dose↑, BioAv↑, ChemoSen↑, *antiAll↑,
6556- BSB,    A Comprehensive Study of Therapeutic Applications of Chamomile
- Review, Nor, NA - Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *AntiBio↑, *hepatoP↑, *AntiCan↑, *other↝, *toxicity↓, *Wound Healing↓, *Dose↝, *Dose↝, *eff↝, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *AST↓, *ALAT↓, *antiAll↑,
6557- BSB,    Alpha-bisabolol protects against neonatal asthma by suppressing airway inflammatory signaling
- in-vivo, Nor, NA
*ROS↓, *Inflam↓, *IL1β↓, *IL6↓, *IL8↓, *IL17↓, *CXCR4↓, *COX2/PTGS2↓, *TLR4↓, *NO↓, *MDA↓, *XO↓, *antiAll↑,
5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, Asthma, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2/PTGS2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *Synergy↑, *BChE↓, *CRP↓, *antiAll↑,
9141- CC,    Camu Camu (Myrciaria dubia (Kunth) McVaugh): An Amazonian Fruit with Biofunctional Properties–A Review
- Review, Nor, NA
*Ingr↝, *antiOx↑, *hyperG↓, *Obesity↓, *QoL↓, *AntiBio↑, *Inflam↓, *TumCP↓, *hepatoP↑, *Ingr↝, *eff↝, *antiAll↑, *AntiTum↑, *NRF2↑, *NQO1↑, *NA↑,
6093- CHOC,    The relevance of theobromine for the beneficial effects of cocoa consumption
- Review, Nor, NA - NA, Asthma, NA
*toxicity↓, *eff↑, *Half-Life↑, *antiAll↑, *Inflam↓, *HDL↑, *Obesity↓,
2780- CHr,    Anti-cancer Activity of Chrysin in Cancer Therapy: a Systematic Review
- Review, Var, NA
*antiOx↑, Inflam↓, *hepatoP↑, AntiCan↑, Cyt‑c↑, Casp3↑, XIAP↓, p‑Akt↓, PI3K↑, Apoptosis↑, COX2/PTGS2↓, FAK↓, AMPK↑, STAT3↑, MMP↓, DNAdam↑, BAX↑, Bak↑, Casp9↑, p38↑, MAPK↑, TumCCA↑, ChemoSen↑, HDAC8↓, Wnt↓, NF-kB↓, angioG↓, BioAv↓, *antiAll↑,
6820- EMD,    The Health Benefits of Emodin, a Natural Anthraquinone Derived from Rhubarb—A Summary Update
- Review, Nor, NA - Review, Arthritis, NA - Review, AD, NA
*diuretic↑, *Bacteria↓, *Inflam↓, AntiCan↑, TumCP↓, TumCI↓, angioG↓, *toxicity↓, IFN-γ↑, IL12↑, ROS↑, TNF-α↓, TNF-α↓, TGF-β↓, MAPK↓, PKCδ↓, NF-kB↓, HER2/EBBR2↓, VEGF↓, DNAdam↑, Necroptosis↑, Glycolysis↓, GLUT1↓, PI3K↓, Akt↓, Casp9↑, Casp3↑, BAX↑, Bcl-2↓, Synergy↑, MMP2↓, MMP9↓, Synergy↑, ChemoSen↑, P-gp/ABCB1↓, SREBP2↓, Synergy↑, *other↝, *COX2/PTGS2↓, *Hif1a↓, *HDAC↓, *tau↓, *PKCδ↑, *ROS↓, *Inflam↓, AntiAg?, *antiAll↑,
6827- EMD,    Mechanism of Emodin in the Treatment of Rheumatoid Arthritis
- Review, Arthritis, NA
*ALAT↓, *AST↓, *ROS↓, *cardioP↑, *TNF-α↓, *NF-kB↓, *Inflam↓, *AntiArt↑, *PGE2↓, *MMP3↓, *MMP13↓, *COX2/PTGS2↓, *AntiCan↑, *neuroP↑, *hepatoP↑, *antiAll↑,
6814- EMD,    Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics
- Review, Nor, NA
AntiCan↑, *hepatoP↑, *Inflam↑, *antiOx↑, *AntiBio↑, *BioAv↓, *AntiViral↑, *AntiDiabetic↑, *neuroP↑, CSCs↓, NOTCH↓, β-catenin/ZEB1↓, STAT3↓, TumCCA↑, *TNF-α↓, IL6↓, IL1β↓, *MMP9↓, *HO-1↑, cMyc↓, Mcl-1↓, *antiAll↑,
6381- Eug,    Biological Properties and Prospects for the Application of Eugenol—A Review
- Review, Var, NA
*eff↑, *BioAv↝, *CompStab↝, *BioAv↑, *antiOx↑, *AntiAg↑, *Inflam↓, *AntiBio↑, *MAOA↓, *neuroP↑, *ROS↓, *RNS↓, *Synergy↑, NF-kB↓, PGE2↓, COX2/PTGS2↓, TumCCA↑, Apoptosis↑, TumCMig↓, TumCI↓, tumCV↓, PI3K↓, Akt↓, MMPs↓, ChemoSen↑, ALDH↓, *Pain↓, *VGSC↓, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *5LO↓, *chemoPv↑, *antiAll↑,
6981- Form,    Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
BioAv↝, *memory↑, *ROS↓, *AChE↓, *NF-kB↓, *Keap1↝, *NRF2↑, *Inflam↓, *PGC-1α↝, *HO-1↓, *p‑tau↓, *cognitive↑, *BDNF↑, *5HT↑, *Stroke↓, *PARP1↓, *AIF↓, *Casp3↓, NP/CIPN↓, *neuroP↑, *NGF↑, *TNF-α↓, *IL1β↓, *IL18↓, *IL6↓, *VCAM-1↓, *pol-M2 MC↑, *hepatoP↑, *AST↓, *ALAT↓, *LC3II↑, *Beclin-1/ATG6↑, *p62↑, *COX2/PTGS2↑, *MMP↑, *ATP↑, *GSH↑, *Catalase↑, *GPx↑, *MDA↓, *antiPs↑, *AntiDiabetic↑, *glucose↓, *Insulin↑, *GutMicro↑, *Obesity↓, COX2/PTGS2↓, cycD1/CCND1↓, TumCCA↑, EGFR↓, GSK‐3β↑, Mcl-1↓, *toxicity↓, TumCP↓, Hif1a↓, VEGF↓, ERK↓, LAMs↓, Cyt‑c↑, Casp9↑, Casp3↑, PARP↑, TumCD↑, mitA↑, BACH1↓, P53↓, ROS↑, PD-1↓, NF-kB↓, *Bacteria↓, *AntiViral↑, *mt-ROS?, *PI3K↓, *chemoP↑, ChemoSen↑, Synergy↑, *toxicity↓, *BioAv↑, *BioAv↑, *Synergy↑, *antiAll↑,
6562- Ger,    Potential Effects of Geraniol on Cancer and Inflammation-Related Diseases: A Review of the Recent Research Findings
- Review, Var, NA - Review, AD, NA
*Inflam↓, *AntiCan↑, *AntiBio↑, *antiOx↑, *neuroP↑, ROS↓, Apoptosis↑, TumCCA↑, P53↝, STAT3↓, Casp↝, *Catalase↑, *GSTs↑, *GPx↑, *AChE↓, *GSH↑, *SOD↑, *TBARS↓, *NO↓, *XO↓, *memory↑, *IL1β↓, *iNOS↓, *NF-kB↓, *COX2/PTGS2↓, *NRF2↑, *HO-1↑, *survivin↓, TumCP↓, TumCMig↓, TumCG↑, selectivity↑, TumMeta↓, angioG↓, Hif1a↓, Beclin-1/ATG6↓, *antiAll↑,
7325- GSE,    The Effects of a Grape Seed Procyanidin Extract on Cytochrome P450 3A4 Activity and Inflammatory Mediators in the Lungs of Heavy Active and Former Smokers
- in-vitro, Lung, NA
*cardioP↑, *Inflam↓, BioAv↑, TNF-α↓, MIP‑1α/CCL3↓, GranB/GZMB↓, *antiAll↑, *MIP‑1α/CCL3↓,
7482- H2,    Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA - Review, Sepsis, NA - Review, AD, NA
Dose↝, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *neuroP↑, *mTOR↓, *IL10↑, *TGF-β↑, *Sepsis↓, *NRF2↑, *antiOx↑, *Catalase↑, *SOD↑, *GPx↑, *ROS↓, *HO-1↑, *PI3K↑, *Akt↑, *hepatoP↑, *MPO↓, *cardioP↑, CDK4↓, CDK6↑, CD47↓, PI3K↓, Akt↓, Hif1a↓, selectivity↑, *MMP↑, *ATP↑, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *p38↓, *p‑JNK↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p‑eIF2α↓, *ATF4↓, *XBP-1↓, *Imm↑, *IFN-γ↓, *IL4↓, *GranB/GZMB↓, NK cell↑, radioP↑, *CD4+↑, CD8+↑, *Dose↝, *other↑, *Dose↝, *antiPs↑, *BioAv↝, *GutMicro↑, Dose↝, *IBI↑, TumCP↓, TumCI↓, TumCMig↓, CD8+↑, PGC-1α↑, Akt↓, SCD1↓, *MDA↓, Synergy↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *cognitive↑, *neuroP↑, NP/CIPN↓, *Stroke↓, *NLRP3↓, *ALAT↓, *AST↓, *LPS↓, *hepatoP↑, chemoP↑, *creat↓, *Urea↓, *RenoP↑, *eff↑, Apoptosis↑, XIAP↓, IAP2/BIRC3↓, TumVol↓, MALAT1↓, EZH2↓, miR-124-3p↓, eff↑, ChemoSen↑, *compII↑, *compIII↑, *LDL↓, *Obesity↓, QoL↑, PFS↑, *antiAll↑,
7487- H2,    A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives
- Review, Nor, NA
*Inflam↓, *antiOx↓, *Stress↓, *Dose↝, *cardioP↑, *GastroP↑, *BBB↑, *eff↑, *toxicity↓, *Dose↝, *hepatoP↑, *ROS↓, *SOD↑, *TBARS↓, *HDL↑, *LDL↓, *Obesity↓, *GSH↑, *TNF-α↓, *GutMicro↑, *DNAdam↓, *γH2AX↓, *p‑p38↓, *NF-kB↓, *antiAll↑,
7489- H2,    Molecular Hydrogen in the Treatment of Respiratory Diseases
- Review, Asthma, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *Dose↓, *Dose↝, *eff↑, *ROS↓, *RNS↓, *NRF2↑, *HO-1↑, *Fenton↓, *NLRP3↓, *NADPH↓, *NOX4↓, *NOX↓, *MPO↓, *NF-kB↓, *TNF-α↓, *IL6↓, *IL1β↓, *HMGB1↓, *IL4↑, *IL10↑, *M2 MC↑, *Treg lymp↝, *Bcl-2↑, *Bcl-xL↑, *PI3K↑, *Akt↑, *JAK2↑, *STAT3↑, *Dose↑, *CD4+↑, *CD25+↑, *FOXP3↑, *MDA↓, *SOD↑, *Catalase↑, *Casp3↓, *Casp9↓, *TBARS↓, *SpO2↑, *VitE↓, *OS↑, *Weight↑, *DNAdam↓, *PGE2↓, *MCP1/CCL2↓, *lipid-P↓, *TumCP↓, *tumCV↓, *TumCMig↓, *TumCI↓, TumW↓, TumVol↓, selectivity↑, QoL↑, ChemoSen↑, chemoP↑, radioP↑, ROS↑, NLRP3↑, Casp3↑, VEGF↓, Wnt↓, β-catenin/ZEB1↓, *antiAll↑,
7927- H2,    Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients
- Human, Asthma, NA
*IL8↓, *IL4↓, *IL6↓, *Inflam↓, *Sepsis↓, *Stroke↓, *antiOx↑, *toxicity↓, *antiAll↑,
7928- H2,    Molecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis
- in-vivo, Asthma, NA
*IL33↓, *NF-kB↓, *IL1RL1/ST2↓, *ILC2↓, *E-cadherin↑, *ZO-1↑, *Inflam↓, *antiAll↑,
7929- H2,    Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma
- in-vivo, Asthma, NA
*IL4↓, *IL5↓, *IL13↓, *TNF-α↓, *AirwayM↓, *MUC5AC↓, *COL3A1↓, *VEGF↓, *NF-kB↓, *Inflam↓, *antiAll↑,
7926- H2,    Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model
- in-vivo, Asthma, NA
*Dose↝, *Airway↓, *BALF-Infl↓, *Th2↓, *IL4↓, *IgE↓, *MDA↓, *SOD↑, *NF-kB↓, *NRF2↑, *antiAll↑,
7925- H2,    Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice
- in-vivo, Asthma, NA
*Dose?, *IL4↓, *IL13↓, *TNF-α↓, *CXCL15↓, *SOD↑, *MDA↓, *MPO↓, *ROS↓, *antiOx↑, *Inflam↓, *Apoptosis↓, *toxicity↓, *Stroke↓, *Airway↓, *Neut↓, *Eos↓, *BALF-Lym↓, *BALF-Infl↓, *AirwayM↓, *antiAll↑,
7930- H2,    Hydrogen-rich water alleviates asthma airway inflammation by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation
- in-vivo, Asthma, NA
*GutMicro↑, *Inflam↓, *Dose↝, *AirwayM↓, *antiAll↑,
7931- H2,    Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells
- in-vitro, Asthma, NA
*p‑FcεRI↓, *NADPH↓, *H2O2↓, *Dose↝, *antiAll↑,
7932- H2,    Hydrogen Gas Inhalation Alleviates Airway Inflammation and Oxidative Stress on Ovalbumin-Induced Asthmatic BALB/c Mouse Model
- in-vivo, Asthma, NA
*antiOx↑, *Inflam↓, *ROS↓, *TAC↑, *IgE↓, *Dose↝, *NLR↓, *IL4↓, *IL5↓, *IL13↓, *GM-CSF↓, *NO↓, *GPx↑, *Eos↓, *antiAll↑,
7933- H2,    Hydrogen inhalation ameliorates lung inflammation in mice with asthma
- in-vivo, Asthma, NA
*antiOx↑, *Inflam↓, *IL4↓, *IL5↓, *IL13↓, *IL10↑, *TGF-β1↑, *IgE↓, *MDA↓, *SOD↑, *Airway↓, *antiAll↑,
7934- H2,    Hydrogen-generating silicon-based agent is effective in a mouse model of ovalbumin-induced allergic bronchial asthma
- in-vivo, Asthma, NA
*IgE↓, *antiOx↑, *Eos↓, *BALF-Infl↓, *IL5↓, *IL13↓, *CCL11↓, *antiAll↑,
2512- H2,    Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch
- in-vivo, Asthma, NA
*selectivity↑, *lactateProd↓, *ATP↑, *HK2↓, *PFK↓, *Hif1a↓, *PGC-1α↑, *Glycolysis↓, *OXPHOS↑, *Dose↝, *antiAll↑,
2508- H2,    Molecular hydrogen is a promising therapeutic agent for pulmonary disease
- Review, Var, NA - Review, Sepsis, NA
*ROS↓, eff↝, *Inflam↓, *NRF2↑, *HO-1↑, *SOD↑, *Catalase↑, *MPO↑, *ASK1↓, *NADPH↓, *Sepsis↓, *HMGB1↓, ROS↑, NLRP3↑, GSDMD↑, chemoP↑, eff↑, *antiAll↑,
8517- HNK,  MAG,    Modulation of Rat Hepatic CYP1A and 2C Activity by Honokiol and Magnolol: Differential Effects on Phenacetin and Diclofenac Pharmacokinetics In Vivo
- in-vivo, Nor, NA
Ingr↝, CYP1A1↓, *antiAll↑, *Stress↓, *Inf↓,
7814- ISQ,    Isoquercitrin Attenuates Steatohepatitis by Inhibition of the Activated NLRP3 Inflammasome through HSP90
- in-vivo, Nor, NA
*ROS↓, *AntiCan↑, *cardioP↑, *AntiDiabetic↑, *NLRP3↓, *HSP90↓, *AST↓, *ALAT↓, *antiAll↑,
7791- ISQ,    Isoquercitrin: pharmacology, toxicology, and metabolism
- Review, Nor, NA
*BioAv↑, *chemoP↑, *ROS↓, *cardioP↑, *AntiDiabetic↑, *Dose↝, *antiAll↑,
8105- KAE,    Chemo-preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review
- Review, Var, NA
Apoptosis↑, tumCV↓, TumCCA↑, PI3K↓, Akt↓, EMT↓, N-cadherin↓, E-cadherin↓, Slug?, Snail?, MMP2↓, MMP9↓, CTSB↓, CTSD↓, Casp3↑, Casp8↑, Casp9↑, TIMP2↓, Akt↓, TumCD↑, i-Ca+2↑, MMP↓, *ROS↓, *SOD↑, *Catalase↑, *GPx↑, *GSTs↑, *AST↓, *ALAT↓, *MDA↓, *CYP2E1↓, *NRF2↑, *AGEs↓, *IL6↓, *TNF-α↓, *NF-kB↓, *Casp3↓, *BAX↓, *antiAll↑, *COX2/PTGS2↓, *PGE2↓, *RUNX2↑, *BMP2↑, *COL1↑, *p62↑, *FASN↓, *DGAT1↓, FOXP3↑, DNAdam↑, ROS↑, Catalase↓, *ROS↓, *MMP↑, *Cyt‑c↓, *AntiDiabetic↑, *Obesity↓, *cardioP↑,
8154- lamb,    Anti-allergic effect of lambertianic acid from Thuja orientalis in mouse bone marrow-derived mast cells
- in-vitro, Nor, NA
*IL6↓, *PGD2↓, *LTC4↓, *COX2/PTGS2↓, *β-HEX↓, *antiAll↑,
8150- lamb,    Reactive oxygen species dependent phosphorylation of the liver kinase B1/AMP activated protein kinase/ acetyl-CoA carboxylase signaling is critically involved in apoptotic effect of lambertianic acid in hepatocellular carcinoma cells
- in-vitro, HCC, HepG2 - in-vitro, HCC, SK-HEP-1
lipidLev↓, TumCCA↑, cl‑Casp3↑, cl‑PARP↑, AMPK↑, Akt↓, mTOR↓, Bcl-2↓, Bcl-xL↓, COX2/PTGS2↓, ROS↑, eff↓, p‑STK11/LKB1↑, p‑ACC↑, *Obesity↓, *Stress↓, *antiAll↑, tumCV↓, selectivity↑, TumCP↓, *antiAll↑,
8148- lamb,    Anti-Cancer Effect of Lambertianic Acid by Inhibiting the AR in LNCaP Cells
- in-vitro, Pca, LNCaP
*antiAll↑, *Bacteria↓, AR↓, PSA↓, TumCCA↑, CDK4↓, CDK6↓, cycD1/CCND1↓, P53↑, P21↑, p27/CDKN1B↓, Apoptosis↑, cl‑Casp9↑, cl‑Casp3↑, cl‑PARP↑, BAX↑, Bcl-2↓, Dose↝,
8156- lamb,    A review on chemistry, source and therapeutic potential of lambertianic acid
- Review, Var, NA
*Obesity↓, *AntiCan↑, *AMPK↑, *β-HEX↓, NA↑, TumCCA↑, AMPK↑, ACC↑, p‑Akt↓, FOXM1↓, CycB/CCNB1↓, XIAP↓, Bcl-2↓, p‑STAT3↓, p‑NF-kB↓, Bcl-xL↓, survivin↓, VEGF↓, COX2/PTGS2↓, cMyc↓, IL6↓, TNF-α↓, ROS↑, STK11/LKB1↑, cl‑Casp3↑, cl‑PARP↑, Synergy↑, AR↓, TumCP↓, p‑P53↓, P21↓, p27/CDKN1B↓, cycD1/CCND1↓, CDK4↓, PSA↓, STAT3↓, ac‑p65↓, *antiAll↑,
8237- LCA,    Role of Licochalcone A in Potential Pharmacological Therapy: A Review
- Review, Var, NA
*other↝, *Inflam↓, *Bacteria↓, *antiOx↑, *AntiP↑, *neuroP↑, *glucose↝, *lipid-P↓, PKCδ↓, P70S6K↓, Akt↓, ER Stress↑, Apoptosis↑, Ca+2↑, PI3K↓, mTOR↓, Casp3↑, Bcl-2↓, Cyt‑c↑, BAX↑, cl‑PARP↑, cycD1/CCND1↑, ROS↑, CHOP/DDIT3↑, ERK↑, p38↑, JNK↓, IAP1↓, XIAP↓, survivin↓, cFLIP↓, RIP1↓, EGFR↓, MET↓, HER2/EBBR2↓, p‑4E-BP1↓, PERK↑, eIF2α↑, PD-L1↓, HK2↓, Glycolysis↓, Sp1/3/4↓, FasL↑, MMP↓, ATP↓, TumAuto↑, WEE1↑, P21↑, CDK1↓, TumCCA↑, TumCMig↓, TumCI↓, ABCG2↓, HSP90↓, T-Cell↑, CD4+↑, CD25+↑, FOXP3↑, Imm↝, *Inflam↓, *NF-kB↓, *NRF2↑, *AntiArt↑, *antiAll↑, *MUC5AC↓, *E-sel↓, *CCL11↓,
8241- LCA,    Licochalcone A induces apoptotic cell death via JNK/p38 activation in human nasopharyngeal carcinoma cells
- in-vitro, NPC, NA
tumCV↓, Apoptosis↑, Casp8↑, Casp9↑, Casp3↑, cl‑PARP↑, ERK↑, p38↑, JNK↑, *antiAll↑, *Bacteria↓, *Inflam↓, *antiOx↑, *AntiCan↑,

Showing Research Papers: 1 to 50 of 79
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 79

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

Catalase↓, 2,   GSH↓, 1,   lipid-P?, 1,   NRF2↓, 1,   ROS↓, 4,   ROS↑, 17,   SOD↓, 2,   Trx1↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Tf↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 1,   CDC25↓, 2,   compIV↓, 1,   MFN2↑, 1,   mtDam↑, 2,   PGC-1α↑, 1,   SDH↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↑, 1,   p‑ACC↑, 1,   AMPK↓, 1,   AMPK↑, 3,   ATP↓, 2,   Glycolysis↓, 2,   GSK‐3β↓, 1,   GSK‐3β↑, 1,   p‑GSK‐3β↓, 1,   HK2↓, 2,   lipidLev↓, 1,   SCD1↓, 1,   SREBP2↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 2,   APAF1↑, 1,   Apoptosis↑, 15,   Bak↑, 2,   BAX↑, 10,   Bax:Bcl2↑, 3,   Bcl-2↓, 9,   Bcl-xL↓, 3,   BNIP3↑, 1,   Casp↑, 2,   Casp↝, 1,   Casp3↑, 14,   cl‑Casp3↑, 3,   cl‑Casp3⇅, 1,   Casp8↑, 7,   Casp9↓, 1,   Casp9↑, 9,   cl‑Casp9↑, 1,   proCasp9↓, 1,   cFLIP↓, 1,   Cyt‑c↑, 9,   mt-Cyt‑c↓, 1,   Diablo↑, 1,   DR5↑, 4,   FasL↑, 1,   GranB/GZMB↓, 1,   GSDMD↑, 1,   IAP1↓, 3,   IAP2/BIRC3↓, 2,   ICAD↓, 1,   iNOS↓, 1,   Mcl-1↓, 2,   MDM2↓, 1,   Necroptosis↑, 1,   p38↓, 1,   p38↑, 6,   survivin↓, 7,   TRAIL↑, 1,   TumCD↑, 2,   XIAP↓, 6,   XIAP↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 14,   Akt↑, 1,   p‑Akt↓, 5,   cSrc↓, 1,   EGFR↓, 3,   p‑EGFR↓, 1,   ERK↓, 3,   ERK↑, 2,   p‑ERK↓, 3,   HER2/EBBR2↓, 2,   IKKα↓, 1,   JAK2↓, 2,   JNK↓, 1,   JNK↑, 2,   LIMK1↓, 1,   MAPK↓, 2,   MAPK↑, 2,   MAPK↝, 1,   mTOR↓, 5,   mTOR↝, 1,   P70S6K↓, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 11,   PI3K↑, 1,   PKCδ↓, 2,   PTEN↑, 1,   RIP1↓, 1,   Sp1/3/4↓, 1,   STAT3↓, 11,   STAT3↑, 1,   p‑STAT3↓, 2,   STK11/LKB1↑, 1,   p‑STK11/LKB1↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   cJun↑, 1,   cMyc↓, 4,   EZH2↓, 1,   FOXM1↓, 2,   FOXO1↓, 1,   FOXO3↓, 1,   FOXO4↓, 1,   HDAC8↓, 1,   miR-124-3p↓, 1,   miR-200b↑, 1,   miR-34a↓, 1,   OCT4↓, 1,   PAX2↓, 1,   SOX2↓, 1,   SOX9↓, 1,   tumCV↓, 5,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 3,   eIF2α↑, 1,   ER Stress↑, 4,   GRP78/BiP↑, 1,   HSP90↓, 1,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 2,   CTSB↓, 1,   CTSD↓, 1,   LC3II↑, 1,   lysoMP↑, 1,   p62↓, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 4,   hTERT/TERT↓, 1,   P53↓, 1,   P53↑, 7,   P53↝, 1,   p‑P53↓, 1,   PARP↑, 1,   cl‑PARP↑, 12,   PCNA↓, 3,   TOP1↓, 1,   TOP2↓, 1,   TOP2↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 2,   p‑CDK1↓, 1,   CDK2↓, 3,   CDK4↓, 5,   CDK6↓, 1,   CDK6↑, 1,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 2,   cycD1/CCND1↓, 8,   cycD1/CCND1↑, 1,   cycE/CCNE↓, 1,   GADD45A↑, 1,   Ki-67↓, 1,   mitA↑, 1,   P21↓, 1,   P21↑, 6,   p27/CDKN1B↓, 2,   p‑RB1↓, 2,   TumCCA↑, 17,   WEE1↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑4E-BP1↓, 1,   ALDH↓, 1,   CSCs↓, 2,   EIF4E↓, 1,   Ki-67↓, 1,   Let-7↑, 1,   NOTCH↓, 2,   STAT1↓, 1,   TumCG↓, 2,   TumCG↑, 1,   TumCP↓, 9,   Wnt↓, 4,  

Migration(tgid=13) ⓘ

AntiAg?, 1,   BACH1↓, 1,   Ca+2↑, 1,   i-Ca+2↑, 1,   cal2↓, 1,   E-cadherin↓, 4,   E-cadherin↑, 1,   EMT↓, 5,   FAK↓, 2,   LAMs↓, 1,   MALAT1↓, 1,   MET↓, 1,   MMP1↓, 2,   MMP2↓, 11,   MMP9↓, 12,   MMPs↓, 1,   N-cadherin↓, 3,   PDGF↓, 1,   Slug?, 1,   Snail?, 1,   Snail↓, 1,   TGF-β↓, 1,   TIMP2↓, 1,   TumCI↓, 6,   TumCMig↓, 7,   TumMeta↓, 1,   TumMeta↑, 1,   Twist↓, 1,   Vim↓, 2,   β-catenin/ZEB1↓, 4,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 5,   Hif1a↓, 3,   VEGF↓, 14,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,   MMP↓, 6,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD25+↑, 1,   CD4+↑, 1,   CD47↓, 1,   CD8+↑, 2,   COX2/PTGS2↓, 8,   CXCR4↓, 2,   DR4↑, 1,   FOXP3↑, 2,   HMGB1↓, 1,   IFN-γ↑, 1,   IL1↓, 1,   IL12↑, 1,   IL1α↓, 1,   IL1β↓, 1,   IL6↓, 5,   Imm↝, 1,   Inflam↓, 2,   LTA/TNF-β↑, 1,   MCP1/CCL2↓, 1,   MIP‑1α/CCL3↓, 1,   MIP2↓, 1,   NF-kB↓, 11,   p‑NF-kB↓, 1,   NK cell↑, 1,   NLRP3↑, 2,   p65↓, 2,   ac‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 2,   PGE2↓, 2,   PSA↓, 2,   T-Cell↑, 1,   TNF-α↓, 5,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 5,   ER(estro)↓, 1,   PPARα↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 2,   BioAv↑, 3,   BioAv↝, 1,   ChemoSen↑, 14,   CYP1A1↓, 1,   Dose↑, 2,   Dose↝, 5,   eff↓, 1,   eff↑, 3,   eff↝, 1,   Half-Life↓, 1,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 3,   P450↓, 1,   selectivity↑, 6,   Synergy↑, 10,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 5,   ascitic↓, 1,   EGFR↓, 3,   p‑EGFR↓, 1,   EZH2↓, 1,   FOXM1↓, 2,   HER2/EBBR2↓, 2,   hTERT/TERT↓, 1,   IL6↓, 5,   PD-L1↓, 2,   PSA↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 5,   cachexia↓, 1,   cardioP↑, 2,   chemoP↑, 4,   chemoPv↑, 1,   hepatoP↑, 3,   neuroP↑, 1,   NP/CIPN↓, 2,   OS↑, 1,   Pain↓, 1,   PFS↑, 1,   QoL↑, 2,   radioP↑, 3,   Risk↑, 1,   toxicity↓, 1,   TumVol↓, 2,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 2,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 2,  
Total Targets: 300

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 33,   Catalase↑, 18,   Fenton↓, 1,   GPx↑, 11,   GSH↑, 11,   GSR↑, 1,   GSSG↓, 1,   GSTs↓, 1,   GSTs↑, 4,   H2O2↓, 2,   HDL↑, 3,   HO-1↓, 1,   HO-1↑, 10,   hyperG↓, 1,   Keap1↝, 1,   lipid-P↓, 8,   MDA↓, 19,   MPO↓, 5,   MPO↑, 1,   NOX↓, 1,   NOX4↓, 1,   NQO1↑, 2,   NRF2?, 1,   NRF2↑, 18,   Prx↑, 1,   RNS↓, 2,   ROS↓, 34,   ROS↑, 1,   ROS⇅, 1,   mt-ROS?, 1,   SOD↑, 22,   TAC↑, 3,   TBARS↓, 3,   Thiols↑, 2,   VitE↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compII↑, 1,   compIII↑, 1,   HSP60/HSPD1↓, 1,   Insulin↑, 1,   OXPHOS↑, 1,   PGC-1α↑, 1,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 6,   ALAT↓, 11,   AMPK↑, 2,   ATP↑, 4,   DGAT1↓, 1,   FASN↓, 1,   FFA/NEFA↓, 1,   glucose↓, 1,   glucose↝, 1,   Glycolysis↓, 1,   GSK‐3β↓, 3,   HK2↓, 1,   lactateProd↓, 1,   LDL↓, 4,   LTB4↓, 1,   LTC4↓, 2,   NADPH↓, 3,   NADPH↑, 1,   PFK↓, 1,   PLA2↓, 2,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   Apoptosis↓, 3,   ASK1↓, 1,   BAX↓, 2,   Bcl-2↓, 1,   Bcl-2↑, 1,   Bcl-xL↑, 1,   Casp12↓, 1,   Casp3↓, 7,   Casp9↓, 3,   Cyt‑c↓, 2,   GranB/GZMB↓, 1,   iNOS↓, 4,   p38↓, 2,   p‑p38↓, 1,   survivin↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 6,   ERK↓, 1,   JAK2↑, 2,   p‑JNK↓, 2,   MAPK↓, 1,   MAPK↑, 1,   mTOR↓, 1,   mTOR↑, 3,   PI3K↓, 2,   PI3K↑, 6,   PKCδ↑, 1,   STAT3↓, 1,   STAT3↑, 2,   STAT6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ATF4↓, 1,   HDAC↓, 1,   other↑, 2,   other↝, 5,   RUNX2↑, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 2,   GRP78/BiP↓, 2,   HSP90↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 2,   Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 1,   p62↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,   PARP1↓, 1,   γH2AX↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   neuroG↑, 1,   TumCP↓, 2,  

Migration(tgid=13) ⓘ

AntiAg↑, 5,   AP-1↓, 3,   Ca+2↑, 1,   Ca+2↝, 1,   COL1↑, 1,   COL3A1↓, 1,   E-cadherin↑, 1,   MMP13↓, 1,   MMP3↓, 2,   MMP9↓, 2,   SLIT2↑, 1,   p‑T-cadherin↓, 1,   TGF-β↓, 2,   TGF-β↑, 1,   TGF-β1↑, 1,   TregCell↑, 1,   TumCI↓, 1,   TumCMig↓, 1,   α-SMA↓, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   CD31/PECAM-1↓, 2,   E-sel↓, 1,   Hif1a↓, 2,   LOX1↓, 1,   NO↓, 7,   NO↑, 1,   TXA2↓, 1,   VCAM-1↓, 1,   VEGF↓, 2,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,   GastroP↑, 2,   IBI↑, 2,   MMP↑, 5,   MUC5AC↓, 2,   TRPA1↑, 1,   TRPV3↑, 1,   VGSC↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

BALF-Infl↓, 3,   BALF-Lym↓, 1,   CCL11↓, 2,   CD25+↑, 1,   CD4+↑, 2,   CD40↓, 1,   COX1↓, 3,   COX2/PTGS2↓, 16,   COX2/PTGS2↑, 1,   CXCc↓, 1,   CXCL15↓, 1,   CXCR4↓, 1,   Eos↓, 8,   p‑FcεRI↓, 1,   FOXP3↑, 1,   GM-CSF↓, 1,   HMGB1↓, 3,   ICAM-1↓, 1,   IFN-γ↓, 2,   IFN-γ↑, 3,   IFN-γ∅, 1,   IgE↓, 7,   IgG1↓, 1,   IL10↓, 2,   IL10↑, 5,   IL10∅, 1,   IL12↓, 2,   IL13↓, 7,   IL17↓, 3,   IL17∅, 1,   IL18↓, 1,   IL1RL1/ST2↓, 1,   IL1β↓, 16,   IL33↓, 1,   IL4↓, 13,   IL4↑, 2,   IL4∅, 1,   IL5↓, 9,   IL6↓, 15,   IL8↓, 4,   ILC2↓, 1,   Imm↑, 2,   Inflam↓, 47,   Inflam↑, 1,   IP-10/CXCL-10↓, 2,   LPS↓, 1,   M2 MC↑, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 5,   MIP‑1α/CCL3↓, 1,   Neut↓, 1,   NF-kB↓, 21,   NF-kB↑, 1,   NLRP3↓, 4,   PGD2↓, 1,   PGE2↓, 10,   PGE2↑, 1,   RAGE↓, 1,   RANTES↓, 1,   SOCS-3↓, 1,   Th1 response↓, 1,   Th2↓, 3,   Th2↑, 2,   TLR4↓, 2,   TNF-α↓, 27,   Treg lymp↝, 1,   β-HEX↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 2,   AChE↓, 7,   BChE↓, 2,   BDNF↑, 1,   ChAT↑, 1,   MAOA↓, 1,   NGF↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 2,   APP↓, 1,   Aβ↓, 5,   Aβ42↓, 1,   BACE/β-secretase↓, 4,   tau↓, 2,   p‑tau↓, 1,   XO↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,   PPARγ↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 6,   BioAv↑, 9,   BioAv↝, 8,   BioEnh↑, 2,   CompStab↝, 1,   CYP2E1↓, 1,   Dose?, 1,   Dose↓, 1,   Dose↑, 1,   Dose↝, 19,   eff↑, 13,   eff↝, 2,   eff∅, 1,   Half-Life↑, 1,   Half-Life↝, 3,   P450↓, 1,   selectivity↑, 1,   Synergy↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 11,   ALP↓, 2,   AST↓, 11,   BloodF↑, 1,   BP↓, 1,   BUN↓, 1,   creat↓, 2,   CRP↓, 2,   FEV1↑, 2,   IL6↓, 15,   LDH↑, 1,   NLR↓, 1,   NOS2↓, 1,   PEF↑, 1,   RAGE↓, 1,   SpO2↑, 1,   TG/TAG↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Airway↓, 3,   AirwayM↓, 4,   Analgesic↑, 1,   antiAll?, 1,   antiAll↑, 79,   antiAll∅, 1,   AntiArt↑, 6,   AntiCan↑, 10,   AntiDiabetic↑, 11,   antiPs↑, 2,   AntiTum↑, 2,   cardioP↑, 17,   chemoP↑, 4,   chemoPv↑, 2,   cognitive↑, 9,   cough?, 1,   diuretic↑, 1,   hepatoP↑, 19,   Learn↑, 1,   memory↑, 7,   motorD↑, 2,   Mucositis↓, 2,   neuroP↑, 21,   Obesity↓, 8,   OS↑, 1,   Pain↓, 2,   QoL↓, 1,   radioP↑, 1,   RenoP↑, 2,   SoreThr?, 1,   Strength↓, 1,   Stress↓, 3,   Stroke↓, 7,   toxicity↓, 13,   toxicity↑, 1,   toxicity↝, 4,   Weight↑, 1,   Wound Healing↓, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 12,   AntiFungal↑, 3,   AntiP↑, 1,   AntiViral↑, 6,   Bacteria↓, 7,   Diar↓, 1,   GutMicro↑, 5,   Inf↓, 1,   Sepsis↓, 4,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 3,  
Total Targets: 329

Scientific Paper Hit Count for: antiAll, antiallergic/antiasmatic
15 Hydrogen Gas
14 Thymoquinone
4 Boswellia (frankincense)
4 lambertianic acid
3 Emodin
3 Luteolin
3 Matrine
3 Piperine
2 1,8-Cineole
2 α-Bisabolol / Chamomile oil
2 isoquercitrin
2 Licochalcone A
2 Quercetin
1 Allicin (mainly Garlic)
1 DTS(dibenzyl trisulphide) from Anamu
1 Artemisinin
1 Astaxanthin
1 Baicalein
1 Benzyl isothiocyanate
1 Phenethyl isothiocyanate
1 Allyl isothiocyanate
1 Carvacrol
1 Camu camu
1 Chocolate
1 Chrysin
1 Eugenol
1 Formononetin
1 Geraniol
1 Grapeseed extract
1 Honokiol
1 Magnolol
1 Kaempferol
1 Licorice
1 Propolis -bee glue
1 Resveratrol
1 Curcumin
1 Rosmarinic acid
1 Rutin
1 Vitamin D3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1745  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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