TBIL Cancer Research Results

TBIL, Total Bilirubin: Click to Expand ⟱
Source:
Type: biomarker

TBIL (Total Bilirubin) — Total concentration of bilirubin in blood, consisting primarily of direct (conjugated) and indirect (unconjugated) bilirubin. TBIL is commonly used as a clinical biomarker of hepatic function, bilirubin metabolism, hemolysis, and biliary obstruction.

Typical modulation in disease: ↑ TBIL may indicate impaired bilirubin clearance, hepatocellular injury, cholestasis, biliary obstruction, or increased red blood cell breakdown. Interpretation depends strongly on the relative direct and indirect fractions.
Scientific Papers found: Click to Expand⟱
8550- Matr,    Matrine improves the hepatic microenvironment and reverses epithelial-mesenchymal transition in hepatocellular carcinoma by inhibiting the Wnt-1/β-catenin signaling pathway
- vitro+vivo, Liver, HUH7
other↝, Wnt↓, β-catenin/ZEB1↓, EMT↓, TumCMig↓, TumCI↓, Inflam↓, hepatoP↑, AST?, ALB↑, ALAT↓, ALP↓, GGT/CD224↓, TBIL↓, DBIL↓, IBIL↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Wnt↓, 1,  

Migration(tgid=13) ⓘ

EMT↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   β-catenin/ZEB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GGT/CD224↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   ALB↑, 1,   ALP↓, 1,   AST?, 1,   DBIL↓, 1,   IBIL↓, 1,   TBIL↓, 1,  

Functional Outcomes(tgid=23) ⓘ

hepatoP↑, 1,  
Total Targets: 17

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TBIL, Total Bilirubin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1859  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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