CARTPT Cancer Research Results

CARTPT, CART Prepropeptide: Click to Expand ⟱
Source:
Type:

CARTPT (CART Prepropeptide; CART) — Neuropeptide precursor that is proteolytically processed into biologically active cocaine- and amphetamine-regulated transcript (CART) peptides. CART peptides regulate appetite, energy balance, body weight, reward, addiction, stress responses, and neuroendocrine signaling.

Typical modulation in cancer: No universal cancer-associated direction. CART/CARTPT has been investigated in selected neuroendocrine and tumor contexts, but it is not currently a broadly established oncogenic or tumor-suppressive target.

Typical modulation in Alzheimer’s disease: Potentially relevant through neuropeptide signaling, neuronal survival, energy balance, and stress-response pathways, but there is no sufficiently established universal AD-specific direction.
Scientific Papers found: Click to Expand⟱
8728- M-Blu,    Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue
- Review, AD, NA
*Dose↝, *antiOx↑, *mitResp↑, *neuroP↑, *memory↑, *CellMemb↑, *BBB↑, *other↝, *compV↑, *OCR↑, *ROS↓, *Sepsis↓, *NO↓, *RNS↓, *memory↑, *tau↓, *CX43/GJA1↑, *THBD↑, *CARTPT↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   RNS↓, 1,   ROS↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compV↑, 1,   mitResp↑, 1,   OCR↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   CellMemb↑, 1,   CX43/GJA1↑, 1,   THBD↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

CARTPT↑, 1,  

Protein Aggregation(tgid=19) ⓘ

tau↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  

Functional Outcomes(tgid=23) ⓘ

memory↑, 2,   neuroP↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

Sepsis↓, 1,  
Total Targets: 18

Scientific Paper Hit Count for: CARTPT, CART Prepropeptide
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1889  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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