VLDL Cancer Research Results

VLDL, Very-Low-Density Lipoprotein: Click to Expand ⟱
Source:
Type:

VLDL (Very-Low-Density Lipoprotein) — Triglyceride-rich lipoprotein produced primarily by the liver that transports endogenous triglycerides, cholesterol, and other lipids through the circulation. VLDL particles are progressively lipolyzed to intermediate-density lipoprotein (IDL) and can ultimately contribute to formation of LDL particles.

Typical modulation: ↑ VLDL, particularly VLDL cholesterol (VLDL-C) or triglyceride-rich VLDL particles, is generally associated with hypertriglyceridemia, insulin resistance, metabolic syndrome, and increased atherogenic lipoprotein burden. ↓ VLDL is generally favorable when baseline triglyceride-rich lipoproteins are elevated.

Typical interpretation: VLDL should be distinguished from LDL and HDL. When a study specifically reports VLDL-C, record VLDL cholesterol rather than assuming that the measurement represents total VLDL particle number or concentration.
Scientific Papers found: Click to Expand⟱
8909- MO,    Effect of Moringa oleifera on inflammatory diseases: an umbrella review of 26 systematic reviews
- Review, Nor, NA
*Ingr↝, *LDL↓, *TG/TAG↓, *TC↓, *HDL↑, *VLDL↓, *ROS↓, *TAC↑, *HK2↑, *Glycolysis↑, *GLUT4↑, Apoptosis↑, P53↑, ROS↑, NF-kB↓, TumCP↓, TumCCA↑, COX2/PTGS2↓, NO↓, MAP2K1/MEK1↓, *GSTs↑, *NQO1↑, *NRF2↑, *ARE↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

MAP2K1/MEK1↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCP↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   NF-kB↓, 1,  
Total Targets: 9

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ARE↑, 1,   GSTs↑, 1,   HDL↑, 1,   NQO1↑, 1,   NRF2↑, 1,   ROS↓, 1,   TAC↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

Glycolysis↑, 1,   HK2↑, 1,   LDL↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT4↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

TC↓, 1,   TG/TAG↓, 1,   VLDL↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 15

Scientific Paper Hit Count for: VLDL, Very-Low-Density Lipoprotein
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1902  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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