Mye Cancer Research Results

Mye, myelosuppression: Click to Expand ⟱

Source:

Type:

Myelosuppression — Suppression of bone-marrow hematopoietic activity resulting in reduced production of one or more blood-cell lineages. It commonly manifests as neutropenia, leukopenia, anemia, thrombocytopenia, or pancytopenia and is a frequent dose-limiting toxicity of cytotoxic chemotherapy and some targeted therapies.

Typical modulation: ↑ myelosuppression is generally unfavorable and indicates greater hematologic toxicity. ↓ myelosuppression is favorable when evaluating treatment tolerability or protective interventions.

Typical mechanistic relationship: Bone-marrow progenitor-cell injury or suppression → hematopoiesis ↓ → neutrophils / leukocytes / erythrocytes / platelets ↓ → infection, fatigue, bleeding, and treatment-delay risk ↑.

Scientific Papers found: Click to Expand⟱

9036-

SP,

The efficacy of dietary Spirulina as an adjunct to chemotherapy to improve immune function and reduce myelosuppression in patients with malignant tumors

Trial,

Var,

cancer patients receiving four cycles of chemotherapy were randomized into control or treatment groups. 40 participants in the control group and 60 in the treatment group

Mye↓, CD8+↑, Imm↑, Dose↝,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD8+↑, 1, Imm↑, 1,

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,

Clinical Biomarkers(tgid=22) ⓘ

Mye↓, 1,
Total Targets: 4

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: Mye, myelosuppression

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells