Database Query Results : , , RAGE

RAGE, Receptor for advanced glycation end-product: Click to Expand ⟱
Source:
Type:
RAGE (receptor for advanced glycation end-product) is thought to be associated with metastasis and poor prognosis of various types of cancer.
Scientific Papers found: Click to Expand⟱
3261- Lyco,    Lycopene and Vascular Health
- Review, Stroke, NA
*Inflam↓, *antiOx↑, *AntiAg↑, *cardioP↑, *SOD↑, *Catalase↑, *ROS↓, *mtDam↓, *cardioP↑, *NF-kB↓, *NO↓, *COX2↓, *LDL↓, *eff↑, *ER Stress↓, *BioAv↑, *eff↑, *MMPs↓, *COX2↓, *RAGE↓,
63- QC,    Quercetin facilitates cell death and chemosensitivity through RAGE/PI3K/AKT/mTOR axis in human pancreatic cancer cells
- in-vitro, Pca, NA
RAGE↓, PI3K↓, mTOR↓, Akt↓, Apoptosis↑, TumAuto↑,
923- QC,    Quercetin as an innovative therapeutic tool for cancer chemoprevention: Molecular mechanisms and implications in human health
- Review, Var, NA
ROS↑, GSH↓, Ca+2↝, MMP↓, Casp3↑, Casp8↑, Casp9↑, other↓, *ROS↓, *NRF2↑, HO-1↑, TumCCA↑, Inflam↓, STAT3↓, DR5↑, P450↓, MMPs↓, IFN-γ↓, IL6↓, COX2↓, IL8↓, iNOS↓, TNF-α↓, cl‑PARP↑, Apoptosis↑, P53↑, Sp1/3/4↓, survivin↓, TRAILR↑, Casp10↑, DFF45↑, TNFR 1↑, Fas↑, NF-kB↓, IKKα↓, cycD1↓, Bcl-2↓, BAX↑, PI3K↓, Akt↓, E-cadherin↓, Vim↓, β-catenin/ZEB1↓, cMyc↓, EMT↓, MMP2↓, NOTCH1↓, MMP7↓, angioG↓, TSP-1↑, CSCs↓, XIAP↓, Snail↓, Slug↓, LEF1↓, P-gp↓, EGFR↓, GSK‐3β↓, mTOR↓, RAGE↓, HSP27↓, VEGF↓, TGF-β↓, COL1↓, COL3A1↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Results for Effect on Cancer/Diseased Cells:
Akt↓,2,   angioG↓,1,   Apoptosis↑,2,   BAX↑,1,   Bcl-2↓,1,   Ca+2↝,1,   Casp10↑,1,   Casp3↑,1,   Casp8↑,1,   Casp9↑,1,   cMyc↓,1,   COL1↓,1,   COL3A1↓,1,   COX2↓,1,   CSCs↓,1,   cycD1↓,1,   DFF45↑,1,   DR5↑,1,   E-cadherin↓,1,   EGFR↓,1,   EMT↓,1,   Fas↑,1,   GSH↓,1,   GSK‐3β↓,1,   HO-1↑,1,   HSP27↓,1,   IFN-γ↓,1,   IKKα↓,1,   IL6↓,1,   IL8↓,1,   Inflam↓,1,   iNOS↓,1,   LEF1↓,1,   MMP↓,1,   MMP2↓,1,   MMP7↓,1,   MMPs↓,1,   mTOR↓,2,   NF-kB↓,1,   NOTCH1↓,1,   other↓,1,   P-gp↓,1,   P450↓,1,   P53↑,1,   cl‑PARP↑,1,   PI3K↓,2,   RAGE↓,2,   ROS↑,1,   Slug↓,1,   Snail↓,1,   Sp1/3/4↓,1,   STAT3↓,1,   survivin↓,1,   TGF-β↓,1,   TNF-α↓,1,   TNFR 1↑,1,   TRAILR↑,1,   TSP-1↑,1,   TumAuto↑,1,   TumCCA↑,1,   VEGF↓,1,   Vim↓,1,   XIAP↓,1,   β-catenin/ZEB1↓,1,  
Total Targets: 64

Results for Effect on Normal Cells:
AntiAg↑,1,   antiOx↑,1,   BioAv↑,1,   cardioP↑,2,   Catalase↑,1,   COX2↓,2,   eff↑,2,   ER Stress↓,1,   Inflam↓,1,   LDL↓,1,   MMPs↓,1,   mtDam↓,1,   NF-kB↓,1,   NO↓,1,   NRF2↑,1,   RAGE↓,1,   ROS↓,2,   SOD↑,1,  
Total Targets: 18

Scientific Paper Hit Count for: RAGE, Receptor for advanced glycation end-product
2 Quercetin
1 Lycopene
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:383  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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